R S Erzurumlu

Summary

Affiliation: Louisiana State University Health Sciences Center
Country: USA

Publications

  1. pmc A chemoattractant role for NT-3 in proprioceptive axon guidance
    Bariş Genç
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, USA
    PLoS Biol 2:e403. 2004
  2. pmc Molecular determinants of the face map development in the trigeminal brainstem
    Reha S Erzurumlu
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Anat Rec A Discov Mol Cell Evol Biol 288:121-34. 2006
  3. pmc Neural activity: sculptor of 'barrels' in the neocortex
    R S Erzurumlu
    Department of Cell Biology and Anatomy and Neuroscience Center, LSUHSC, New Orleans, LA 70012, USA
    Trends Neurosci 24:589-95. 2001
  4. ncbi request reprint Regulation of neurotrophin-induced axonal responses via Rho GTPases
    P H Ozdinler
    Department of Cell Biology and Anatomy, LSUHSC, New Orleans, Louisiana 70112, USA
    J Comp Neurol 438:377-87. 2001
  5. pmc Neonatal deafferentation does not alter membrane properties of trigeminal nucleus principalis neurons
    F S Lo
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Neurophysiol 85:1088-96. 2001
  6. ncbi request reprint Target specific differentiation of peripheral trigeminal axons in rat-chick chimeric explant cocultures
    A S Haeberle
    Neuroscience Center, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Brain Res Dev Brain Res 131:1-8. 2001
  7. pmc Whisker-related neural patterns develop normally despite severe whisker defects in Msx2 knockout mice
    B Genc
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Brain Res Dev Brain Res 132:107-11. 2001
  8. pmc Synaptic plasticity in the trigeminal principal nucleus during the period of barrelette formation and consolidation
    W Guido
    Department of Cell Biology and Anatomy, Neuroscience Center for Excellence, Louisiana State Health Science Center, New Orleans, LA 70112, USA
    Brain Res Dev Brain Res 132:97-102. 2001
  9. pmc NMDA receptor-dependent regulation of axonal and dendritic branching
    Li Jen Lee
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Neurosci 25:2304-11. 2005
  10. ncbi request reprint Local neurotrophin effects on central trigeminal axon growth patterns
    P Hande Ozdinler
    Department of Cell Biology and Anatomy, LSU Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Brain Res Dev Brain Res 151:55-66. 2004

Collaborators

  • F S Lo
  • P C Kind
  • Mark F Jacquin
  • Takuji Iwasato
  • P Hande Ozdinler
  • Li Jen Lee
  • Emel Ulupinar
  • Bariş Genç
  • Akash Datwani
  • Shigeyoshi Itohara
  • Gabriel C Quintero
  • W Guido
  • B Genc
  • P H Ozdinler
  • A S Haeberle
  • Anthony L Vaccarino
  • April E Mendoza
  • Nedim Unal
  • L Ma

Detail Information

Publications23

  1. pmc A chemoattractant role for NT-3 in proprioceptive axon guidance
    Bariş Genç
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, USA
    PLoS Biol 2:e403. 2004
    ..Our results show that survival factor NT-3 acts as a short-distance axon guidance molecule for muscle sensory afferents as they approach their proper targets...
  2. pmc Molecular determinants of the face map development in the trigeminal brainstem
    Reha S Erzurumlu
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Anat Rec A Discov Mol Cell Evol Biol 288:121-34. 2006
    ..Similar mechanisms may also be used by trigeminothalamic and thalamocortical projections in establishing patterned neural modules upstream from the trigeminal brainstem...
  3. pmc Neural activity: sculptor of 'barrels' in the neocortex
    R S Erzurumlu
    Department of Cell Biology and Anatomy and Neuroscience Center, LSUHSC, New Orleans, LA 70012, USA
    Trends Neurosci 24:589-95. 2001
    ..Here we review recent evidence that is finally opening the doors to understanding the cellular and molecular mechanisms of pattern formation in the neocortex...
  4. ncbi request reprint Regulation of neurotrophin-induced axonal responses via Rho GTPases
    P H Ozdinler
    Department of Cell Biology and Anatomy, LSUHSC, New Orleans, Louisiana 70112, USA
    J Comp Neurol 438:377-87. 2001
    ..Our results demonstrate that Rho GTPases play a major role in neurotrophin-induced axonal differentiation of embryonic trigeminal axons...
  5. pmc Neonatal deafferentation does not alter membrane properties of trigeminal nucleus principalis neurons
    F S Lo
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Neurophysiol 85:1088-96. 2001
    ..The results of the present study demonstrate that distinct membrane properties of barrelette and interbarrelette cells are maintained even in the absence of input from the whiskers during the critical period of pattern formation...
  6. ncbi request reprint Target specific differentiation of peripheral trigeminal axons in rat-chick chimeric explant cocultures
    A S Haeberle
    Neuroscience Center, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Brain Res Dev Brain Res 131:1-8. 2001
    ..Collectively these results indicate that both the chick and rat TG cells respond to similar target-specific peripheral cues in the establishment of innervation density and patterning in peripheral orofacial targets...
  7. pmc Whisker-related neural patterns develop normally despite severe whisker defects in Msx2 knockout mice
    B Genc
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Brain Res Dev Brain Res 132:107-11. 2001
    ..We conclude that whisker-related neural patterns can form in the absence of normal whiskers, as long as whisker follicle innervation is intact...
  8. pmc Synaptic plasticity in the trigeminal principal nucleus during the period of barrelette formation and consolidation
    W Guido
    Department of Cell Biology and Anatomy, Neuroscience Center for Excellence, Louisiana State Health Science Center, New Orleans, LA 70112, USA
    Brain Res Dev Brain Res 132:97-102. 2001
    ..These associative processes may regulate the patterning and maintenance of whisker-specific patterns in the brainstem trigeminal nuclei...
  9. pmc NMDA receptor-dependent regulation of axonal and dendritic branching
    Li Jen Lee
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Neurosci 25:2304-11. 2005
    ..These results indicate that NMDARs regulate growth of presynaptic terminal arbors and postsynaptic dendritic branching, thereby leading to consolidation of synapses and patterning of presynaptic and postsynaptic elements...
  10. ncbi request reprint Local neurotrophin effects on central trigeminal axon growth patterns
    P Hande Ozdinler
    Department of Cell Biology and Anatomy, LSU Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Brain Res Dev Brain Res 151:55-66. 2004
    ....
  11. pmc Lesion-induced thalamocortical axonal plasticity in the S1 cortex is independent of NMDA receptor function in excitatory cortical neurons
    Akash Datwani
    Department of Cell Biology and Anatomy and Neuroscience Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Neurosci 22:9171-5. 2002
    ....
  12. pmc L-type calcium channel-mediated plateau potentials in barrelette cells during structural plasticity
    Fu Sun Lo
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans 70112, USA
    J Neurophysiol 88:794-801. 2002
    ..Increased Ca(2+) entry may play a key role in injury-induced structural remodeling, and/or transsynaptic cell death...
  13. ncbi request reprint Slit2, a branching-arborization factor for sensory axons in the Mammalian CNS
    P Hande Ozdinler
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Neurosci 22:4540-9. 2002
    ..Spatiotemporal expression of Slit2 and Robo receptor mRNAs within the brainstem trigeminal nuclei and the trigeminal ganglion during elongation and branching-arborization further corroborates our experimental results...
  14. pmc Altered parcellation of neocortical somatosensory maps in N-methyl-D-aspartate receptor-deficient mice
    Li Jen Lee
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Comp Neurol 485:57-63. 2005
    ..Our findings indicate that both subcortical and cortical mechanisms contribute to cortical parcellation of body map subdivisions in an NMDA receptor-dependent manner...
  15. pmc Conversion of functional synapses into silent synapses in the trigeminal brainstem after neonatal peripheral nerve transection
    Fu Sun Lo
    Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Neurosci 27:4929-34. 2007
    ..Sensory deprivation most likely results in AMPA receptor endocytosis and/or lateral diffusion to the extrasynaptic membrane...
  16. pmc Decreased pain response in mice following cortex-specific knockout of the N-methyl-D-aspartate NR1 subunit
    Gabriel C Quintero
    Neuroscience Center of Excellence, Louisiana State University Health Science Center, New Orleans, LA 70112, USA
    Neurosci Lett 425:89-93. 2007
    ..01). By contrast, no differences among groups were found in PWL to a noxious thermal stimulus. Taken together, these results demonstrate dissociation in the role of cortical NMDA receptors in mediating different types of pain...
  17. pmc Differential Trk expression in explant and dissociated trigeminal ganglion cell cultures
    Bariş Genç
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, Louisiana 70112, USA
    J Neurobiol 64:145-56. 2005
    ..Our results indicate that wholemount explant cultures of sensory ganglia represent in vivo conditions in terms of Trk expression patterns; whereas dissociation dramatically alters Trk expression by primary sensory neurons...
  18. pmc Exuberant thalamocortical axon arborization in cortex-specific NMDAR1 knockout mice
    Li Jen Lee
    Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Comp Neurol 485:280-92. 2005
    ..Given that thalamic NMDARs are spared in CxNR1KO mice, the present results show that postsynaptic NMDARs play an important role in refinement of presynaptic afferent arbors and whisker-specific patterning in the developing barrel cortex...
  19. ncbi request reprint Dose and age-dependent axonal responses of embryonic trigeminal neurons to localized NGF via p75NTR receptor
    P Hande Ozdinler
    Department of Cell Biology and Anatomy, LSU Health Sciences Center, 1901 Perdido Street, New Orleans, Louisiana 70112, USA
    J Neurobiol 62:189-206. 2005
    ..Collectively, our results suggest that localized sources of NGF can direct axon outgrowth from trigeminal ganglion in a dose- and age-dependent fashion, mediated by p75NTR signaling through TrkA expressing axons...
  20. ncbi request reprint Morphometric analysis of embryonic rat trigeminal neurons treated with different neurotrophins
    Emel Ulupinar
    Department of Anatomy, Osmangazi University Faculty of Medicine, Eskisehir, Turkey
    Anat Rec A Discov Mol Cell Evol Biol 277:396-407. 2004
    ..These results show that exposure to NGF leads to phenotypic changes in TrkA-expressing trigeminal neurons at early embryonic development, but selective survival of small diameter neurons at later ages...
  21. pmc Somatosensory cortical plasticity: recruiting silenced barrels by active whiskers
    Reha S Erzurumlu
    Department of Cell Biology and Anatomy and Neuroscience Center, LSU Health Sciences Center, New Orleans, LA 70112, USA
    Exp Neurol 184:565-9. 2003
  22. pmc NMDA receptor-dependent pattern transfer from afferents to postsynaptic cells and dendritic differentiation in the barrel cortex
    Akash Datwani
    Laboratory for Behavioral Genetics, Brain Science Institute BSI, RIKEN, 2 1 Hirosawa, Wako Shi, Saitama, 351 0198, Japan
    Mol Cell Neurosci 21:477-92. 2002
    ..When postsynaptic NMDAR function is disrupted, layer IV spiny stellate cells remain imperceptive to patterning of their presynaptic inputs and elaborate exuberant dendritic specializations...
  23. pmc Cortical adenylyl cyclase 1 is required for thalamocortical synapse maturation and aspects of layer IV barrel development
    Takuji Iwasato
    Laboratory for Behavioral Genetics, RIKEN Brain Science Institute, Saitama 351 0198, Japan
    J Neurosci 28:5931-43. 2008
    ..They also suggest that the formation of the gross morphological features of barrels is independent of postsynaptic AC1 in the barrel cortex...