D S Dwyer

Summary

Affiliation: Louisiana State University Health Sciences Center
Country: USA

Publications

  1. ncbi An ethanol-sensitive variant of the PC12 neuronal cell line: sensitivity to alcohol is associated with increased cell adhesion and decreased glucose accumulation
    D S Dwyer
    Department of Psychiatry, LSU Medical Center Shreveport, Shreveport, Louisiana, 71130, USA
    J Cell Physiol 178:93-101. 1999
  2. ncbi Molecular simulation of the effects of alcohols on peptide structure
    D S Dwyer
    Department of Psychiatry, LSU Medical Center Shreveport 71130, USA
    Biopolymers 49:635-45. 1999
  3. ncbi Antipsychotic drugs affect glucose uptake and the expression of glucose transporters in PC12 cells
    D S Dwyer
    Department of Psychiatry, LSU Medical Center Shreveport Shreveport, USA
    Prog Neuropsychopharmacol Biol Psychiatry 23:69-80. 1999
  4. ncbi Dopamine receptor antagonists modulate glucose uptake in rat pheochromocytoma (PC12) cells
    D S Dwyer
    Department of Psychiatry, Louisiana State University Medical Center, Shreveport 71130 3932, USA
    Neurosci Lett 274:151-4. 1999
  5. ncbi Chemical properties of alcohols and their protein binding sites
    D S Dwyer
    LSU Medical Center Shreveport, Department of Psychiatry, Louisiana 71130, USA
    Cell Mol Life Sci 57:265-75. 2000
  6. ncbi Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine
    T D Ardizzone
    Department of Pharmacology, LSU Health Sciences Center, 1501 Kings Hwy, Shreveport, LA 71130, USA
    Brain Res 923:82-90. 2001
  7. ncbi Glucose metabolism in relation to schizophrenia and antipsychotic drug treatment
    D S Dwyer
    Department of Psychiatry, LSU Health Sciences Center Shreveport, Louisiana 71130 3932, USA
    Ann Clin Psychiatry 13:103-13. 2001
  8. ncbi Electronic properties of the amino acid side chains contribute to the structural preferences in protein folding
    D S Dwyer
    Department of Psychiatry, LSU Health Sciences Center Shreveport, 71130 3932, USA
    J Biomol Struct Dyn 18:881-92. 2001

Detail Information

Publications8

  1. ncbi An ethanol-sensitive variant of the PC12 neuronal cell line: sensitivity to alcohol is associated with increased cell adhesion and decreased glucose accumulation
    D S Dwyer
    Department of Psychiatry, LSU Medical Center Shreveport, Shreveport, Louisiana, 71130, USA
    J Cell Physiol 178:93-101. 1999
    ..Thus, there appears to be an interplay between energy metabolism in the cell and the response to ethanol...
  2. ncbi Molecular simulation of the effects of alcohols on peptide structure
    D S Dwyer
    Department of Psychiatry, LSU Medical Center Shreveport 71130, USA
    Biopolymers 49:635-45. 1999
    ..The data suggest that alcohols at low concentrations affect protein structure mainly through a combination of hydrogen-bonding and hydrophobic interactions that are influenced by the properties of the solvent...
  3. ncbi Antipsychotic drugs affect glucose uptake and the expression of glucose transporters in PC12 cells
    D S Dwyer
    Department of Psychiatry, LSU Medical Center Shreveport Shreveport, USA
    Prog Neuropsychopharmacol Biol Psychiatry 23:69-80. 1999
    ....
  4. ncbi Dopamine receptor antagonists modulate glucose uptake in rat pheochromocytoma (PC12) cells
    D S Dwyer
    Department of Psychiatry, Louisiana State University Medical Center, Shreveport 71130 3932, USA
    Neurosci Lett 274:151-4. 1999
    ..These findings may have implications for the adverse effects of these drugs and for the interpretation of imaging studies of brain glucose metabolism in patients on antipsychotic medications...
  5. ncbi Chemical properties of alcohols and their protein binding sites
    D S Dwyer
    LSU Medical Center Shreveport, Department of Psychiatry, Louisiana 71130, USA
    Cell Mol Life Sci 57:265-75. 2000
    ..Binding at these sites may alter the local protein structure or displace bound solvent molecules and perturb the function of key proteins...
  6. ncbi Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine
    T D Ardizzone
    Department of Pharmacology, LSU Health Sciences Center, 1501 Kings Hwy, Shreveport, LA 71130, USA
    Brain Res 923:82-90. 2001
    ..Furthermore, this work may provide clues about how the antipsychotic drugs produce hyperglycemia in vivo...
  7. ncbi Glucose metabolism in relation to schizophrenia and antipsychotic drug treatment
    D S Dwyer
    Department of Psychiatry, LSU Health Sciences Center Shreveport, Louisiana 71130 3932, USA
    Ann Clin Psychiatry 13:103-13. 2001
    ..This paper reviews the relevant literature in a preliminary attempt to understand the implications of such clinical findings in the light of basic research...
  8. ncbi Electronic properties of the amino acid side chains contribute to the structural preferences in protein folding
    D S Dwyer
    Department of Psychiatry, LSU Health Sciences Center Shreveport, 71130 3932, USA
    J Biomol Struct Dyn 18:881-92. 2001
    ..A theoretical model has been proposed to explain how the electronic properties of the side chain groups might influence folding along the peptide backbone...