P Correa

Summary

Affiliation: Louisiana State University Health Sciences Center
Country: USA

Publications

  1. pmc Non-alcoholic beverages and risk of bladder cancer in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Montevideo, Uruguay
    BMC Cancer 7:57. 2007
  2. ncbi request reprint Chemoprevention of gastric dysplasia: randomized trial of antioxidant supplements and anti-helicobacter pylori therapy
    P Correa
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112 1393, USA
    J Natl Cancer Inst 92:1881-8. 2000
  3. pmc Is gastric cancer preventable?
    P Correa
    Louisiana State University, Department of Pathology, LSU Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Gut 53:1217-9. 2004
  4. ncbi request reprint Commentary: Is prostate cancer an infectious disease?
    Pelayo Correa
    Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Int J Epidemiol 34:197-8. 2005
  5. ncbi request reprint Etiology of gastric cancer: what is new?
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, 1901 Perdido Street, Box P5 1, New Orleans, LA 70112, USA
    Cancer Epidemiol Biomarkers Prev 14:1865-8. 2005
  6. ncbi request reprint New strategies for the prevention of gastric cancer: Helicobacter pylori and genetic susceptibility
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Surg Oncol 90:134-8; discussion 138. 2005
  7. ncbi request reprint Bacterial infections as a cause of cancer
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112 1393, USA
    J Natl Cancer Inst 95:E3. 2003
  8. ncbi request reprint Chemoprevention of gastric cancer: has the time come?
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    J Clin Oncol 21:270s-271s. 2003
  9. pmc Long term follow up of patients treated for Helicobacter pylori infection
    R Mera
    Department of Pathology, Louisiana State University Health Sciences Center, 1901 Perdido St, New Orleans, LA 70112, USA
    Gut 54:1536-40. 2005
  10. ncbi request reprint Morphometric evaluation of gastric antral atrophy: improvement after cure of Helicobacter pylori infection
    B Ruiz
    Department of Pathology, Louisiana State University Medical Center, New Orleans 70112, USA
    Am J Gastroenterol 96:3281-7. 2001

Collaborators

Detail Information

Publications68

  1. pmc Non-alcoholic beverages and risk of bladder cancer in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Montevideo, Uruguay
    BMC Cancer 7:57. 2007
    ..We conducted an additional case-control study in order to further explore the role of non-alcoholic beverages in bladder carcinogenesis...
  2. ncbi request reprint Chemoprevention of gastric dysplasia: randomized trial of antioxidant supplements and anti-helicobacter pylori therapy
    P Correa
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112 1393, USA
    J Natl Cancer Inst 92:1881-8. 2000
    ..Previous research has identified a high risk of gastric carcinoma as well as a high prevalence of cancer precursor lesions in rural populations living in the province of Nariño, Colombia, in the Andes Mountains...
  3. pmc Is gastric cancer preventable?
    P Correa
    Louisiana State University, Department of Pathology, LSU Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Gut 53:1217-9. 2004
    ..Individuals at the highest risk should be cured of their infection and monitored endoscopically to detect dysplasia and "early" cancer, amenable to successful treatment...
  4. ncbi request reprint Commentary: Is prostate cancer an infectious disease?
    Pelayo Correa
    Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Int J Epidemiol 34:197-8. 2005
  5. ncbi request reprint Etiology of gastric cancer: what is new?
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, 1901 Perdido Street, Box P5 1, New Orleans, LA 70112, USA
    Cancer Epidemiol Biomarkers Prev 14:1865-8. 2005
    ..pylori eradication efforts would be most important. This review examines recent studies on interleukin-1beta polymorphisms and H. pylori CagA variation with respect to their modulation of risk for gastric cancer...
  6. ncbi request reprint New strategies for the prevention of gastric cancer: Helicobacter pylori and genetic susceptibility
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Surg Oncol 90:134-8; discussion 138. 2005
    ..They should be targeted for endoscopic monitoring to detect advanced precancerous lesions. The state of the art is briefly reviewed and the needed research identified...
  7. ncbi request reprint Bacterial infections as a cause of cancer
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112 1393, USA
    J Natl Cancer Inst 95:E3. 2003
  8. ncbi request reprint Chemoprevention of gastric cancer: has the time come?
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    J Clin Oncol 21:270s-271s. 2003
  9. pmc Long term follow up of patients treated for Helicobacter pylori infection
    R Mera
    Department of Pathology, Louisiana State University Health Sciences Center, 1901 Perdido St, New Orleans, LA 70112, USA
    Gut 54:1536-40. 2005
    ..Understanding long term effects resulting from the cure of this infection is needed to design cancer prevention strategies...
  10. ncbi request reprint Morphometric evaluation of gastric antral atrophy: improvement after cure of Helicobacter pylori infection
    B Ruiz
    Department of Pathology, Louisiana State University Medical Center, New Orleans 70112, USA
    Am J Gastroenterol 96:3281-7. 2001
    ..CONCLUSIONS: We conclude that gastric atrophy improves significantly after long term control of H. pylori infection. This effect can be demonstrated both by conventional histological grading and by morphometry...
  11. ncbi request reprint KRAS mutations are not predictive for progression of preneoplastic gastric lesions
    J D Hunt
    Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, New Orleans 70112, USA
    Cancer Epidemiol Biomarkers Prev 10:79-80. 2001
    ..Cancer Epidemiol. Biomark. Prevy. 8:167-171, 1999). However, after 6 years, baseline KRAS mutations failed to predict histological progression. Also, KRAS mutation in 72-month biopsies did not predict histological progression...
  12. ncbi request reprint Association of interleukin-1beta gene polymorphisms with precancerous gastric lesions in African Americans and Caucasians
    Jovanny Zabaleta
    Department of Pathology, Stanley S Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Am J Gastroenterol 101:163-71. 2006
    ..The aim of this study was to evaluate the relationship between IL1B and IL1 receptor antagonist gene polymorphisms and the risk of multifocal atrophic gastritis in African Americans and Caucasians...
  13. ncbi request reprint Ethnic differences in cytokine gene polymorphisms: potential implications for cancer development
    Jovanny Zabaleta
    Stanley S Scott Cancer Center, LSUHSC, New Orleans, LA, USA
    Cancer Immunol Immunother 57:107-14. 2008
    ..We hypothesize that these dissimilarities may contribute to differences in the inflammatory response and cancer incidence and mortality between African-Americans and Caucasians in Louisiana...
  14. ncbi request reprint Comparison of genotyping of Helicobacter pylori cagA and vacA virulence genes from gastric biopsies and stool specimens
    Liviu A Sicinschi
    Department of Pathology, Louisiana State University Health Sciences Center and S Scott Cancer Center, New Orleans, LA 70112, USA
    Helicobacter 8:601-7. 2003
    ....
  15. ncbi request reprint Detection and typing of Helicobacter pylori cagA/vacA genes by radioactive, one-step polymerase chain reaction in stool samples from children
    Liviu A Sicinschi
    Department of Pathology, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112 1393, USA
    J Microbiol Methods 52:197-207. 2003
    ..pylori cagA/vacA virulence genes in infected individuals...
  16. ncbi request reprint Helicobacter pylori infection and gastric cancer
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112 1393, USA
    Cancer Epidemiol Biomarkers Prev 12:238s-241s. 2003
  17. ncbi request reprint Morphometric assessment of gastric antral atrophy: comparison with visual evaluation
    B Ruiz
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Histopathology 39:235-42. 2001
    ..The visual grading of atrophy as absent, moderate and severe is entirely consistent with objective morphometric observations...
  18. ncbi request reprint Incidence of esophageal and gastric cancers among Hispanics, non-Hispanic whites and non-Hispanic blacks in the United States: subsite and histology differences
    Xiaocheng Wu
    Epidemiology, Louisiana State University Health Sciences Center, School of Public Health, 2021 Lakeshore Dr Suite 210, New Orleans, LA 70122, USA
    Cancer Causes Control 18:585-93. 2007
    ..We examined subsite- and histology-specific esophageal and gastric cancer incidence patterns among Hispanics/Latinos and compared them with non-Hispanic whites and non-Hispanic blacks...
  19. ncbi request reprint Age at acquisition of Helicobacter pylori infection: comparison of two areas with contrasting risk of gastric cancer
    M Constanza Camargo
    Department of Pathology, Louisiana State University Health Science Center, New Orleans 70112, USA
    Helicobacter 9:262-70. 2004
    ..pylori infection were present in the two populations...
  20. ncbi request reprint Incidence of esophageal and gastric carcinomas among American Asians/Pacific Islanders, whites, and blacks: subsite and histology differences
    Xiaocheng Wu
    Epidemiology Program, School of Public Health Louisiana Tumor Registry, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
    Cancer 106:683-92. 2006
    ..The authors examined subsite-specific and histology-specific esophageal and gastric carcinoma incidence patterns among the Asians/Pacific Islander (API) population in the United States and compared them with those among whites and blacks...
  21. ncbi request reprint The future of gastric cancer prevention
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, 1901 Perdido St, New Orleans, LA 70112, USA
    Gastric Cancer 7:9-16. 2004
    ..Curing the infection in such subjects and supplying adequate amounts of antioxidants should prevent a neoplastic outcome, and this intervention should be monitored by endoscopic surveillance...
  22. ncbi request reprint Phenotypic differences between esophageal and gastric intestinal metaplasia
    M Blanca Piazuelo
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Mod Pathol 17:62-74. 2004
    ..However, the progression to more advanced lesions could be modulated by the nature of the carcinogenic insult...
  23. ncbi request reprint Effects of a new Helicobacter pylori infection on height and weight in Colombian children
    Robertino Manuel Mera
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
    Ann Epidemiol 16:347-51. 2006
    ..The aim of the study is to investigate whether a new infection caused by Helicobacter pylori in preschool children transiently or permanently affects height and weight...
  24. ncbi request reprint Duration of exposure, a neglected factor in chemoprevention trials
    Elizabeth T H Fontham
    School of Public Health, Louisiana State University Health Sciences Center, 1600 Canal Street, Suite 800, New Orleans, LA 70112, USA
    Cancer Epidemiol Biomarkers Prev 14:2465-6. 2005
  25. ncbi request reprint A positive assay for identification of cagA negative strains of Helicobacter pylori
    Liviu A Sicinschi
    Department of Pathology, Louisiana State University Health Sciences Center and S Scott Cancer Center, 1901 Perdido Street, New Orleans, LA 70112 1393, USA
    J Microbiol Methods 55:625-33. 2003
    ..This noninvasive assay discriminates consistently cagA negative cases from cagA positive strains and from amplification failures. It can be a useful tool for clinical and epidemiological studies of H. pylori infection...
  26. ncbi request reprint Gastric cancer risk in a Mexican population: role of Helicobacter pylori CagA positive infection and polymorphisms in interleukin-1 and -10 genes
    Liviu A Sicinschi
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Int J Cancer 118:649-57. 2006
    ..pylori. Our results support the identification of the IL1B-31 promoter polymorphism as a useful marker for risk of intestinal type gastric cancer in persons with CagA positive H. pylori infections...
  27. ncbi request reprint Gastric neoplasia
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Curr Gastroenterol Rep 4:463-70. 2002
    ..MALT lymphomas have been causally associated with H. pylori infection. Molecular markers are useful to distinguish tumors that respond to H. pylori eradication from those requiring classic chemotherapy...
  28. ncbi request reprint Gene expression in gastric biopsies from patients infected with Helicobacter pylori
    E E Mannick
    Louisiana State University, Stanley S Scott Cancer and Depts of Pathology and Genetics, New Orlands, Louisiana 70112, USA
    Scand J Gastroenterol 39:1192-200. 2004
    ..In this study the effects of H. pylori infection on host gene expression in the gastric antral mucosa in patients were examined...
  29. ncbi request reprint 13C-urea breath test for Helicobacter pylori in young children: cut-off point determination by finite mixture model
    Joanna X Du
    Department of Pathology, Louisiana State University Health Science Center, New Orleans 70112, USA
    Stat Med 23:2049-60. 2004
    ..The cut-off points from those UBT data sets are similar. The advantage of the finite mixture model is that it may be used to calculate sensitivity and specificity in the absence of other diagnostic tests...
  30. ncbi request reprint Infrequency of microsatellite instability in complete and incomplete gastric intestinal metaplasia
    Jone Garay
    Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Hum Pathol 35:102-6. 2004
    ..Our results indicate that MSI is a rare event in intestinal metaplasia in subjects who do not have gastric cancer...
  31. ncbi request reprint Does Helicobacter pylori cause gastric cancer via oxidative stress?
    Pelayo Correa
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Biol Chem 387:361-4. 2006
    ..This review discusses some of the evidence accumulated so far to support such a role. Numerous avenues of research are open and represent an intriguing challenge to the scientific community...
  32. ncbi request reprint Helicobacter pylori arginase inhibits T cell proliferation and reduces the expression of the TCR zeta-chain (CD3zeta)
    Jovanny Zabaleta
    Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    J Immunol 173:586-93. 2004
    ..Furthermore, arginase inhibitors reversed these events. These results suggest that H. pylori arginase is not only important for urea production, but may also impair T cell function during infection...
  33. ncbi request reprint Coming unglued
    Richard M Peek
    Division of Gastroenterology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Clin Cancer Res 12:2951-4. 2006
  34. ncbi request reprint Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: a meta-analysis
    M Constanza Camargo
    Division of Gastroenterology, Hepatology, and Nutrition, Vanderbilt University Medical Center, 2215 Garland Avenue, 1005 MRB IV, Nashville, TN 37232 0252, USA
    Cancer Epidemiol Biomarkers Prev 15:1674-87. 2006
    ..Polymorphisms of interleukin-1B (IL1B) and its receptor antagonist (IL1RN) genes have been inconsistently associated with gastric cancer risk. We examined these associations by performing meta-analyses...
  35. pmc Eosinophils and mast cells in chronic gastritis: possible implications in carcinogenesis
    M Blanca Piazuelo
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Hum Pathol 39:1360-9. 2008
    ..In contrast, in the high-risk area, eosinophils might promote a T helper 1-type response leading to progression of precancerous lesions...
  36. pmc Re: long term follow up of patients treated for Helicobacter pylori infection
    Robertino Mera
    Gut 56:436. 2007
  37. doi request reprint Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions
    Altaf A Dar
    Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Cancer 112:1688-98. 2008
    ..In this study, the authors investigated the prevalence and biological significance of Aurora Kinase A (AURKA) overexpression in upper gastrointestinal adenocarcinomas...
  38. ncbi request reprint Effect of smoking on failure of H. pylori therapy and gastric histology in a high gastric cancer risk area of Colombia
    M Constanza Camargo
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, School of Medicine, Vanderbilt University, Nashville, TN 37232 0252, USA
    Acta Gastroenterol Latinoam 37:238-45. 2007
    ..In the antrum, no significant differences were observed between active-smokers and non-smokers. In summary, in patients who smoked, H. pylori treatment was less effective. Smoking cessation may benefit H. pylori eradication rates...
  39. pmc Interaction of Helicobacter pylori with gastric epithelial cells is mediated by the p53 protein family
    Jinxiong Wei
    Department of Surgery, Vanderbilt University Medical Center and Vanderbilt Ingram Cancer Center, Nashville, Tennessee, USA
    Gastroenterology 134:1412-23. 2008
    ..Accumulating evidence suggests that both p73 and p63 play important roles in regulation of apoptosis, cell differentiation, and therapeutic drug sensitivity...
  40. pmc Regulation of gastric carcinogenesis by Helicobacter pylori virulence factors
    Aime T Franco
    Division of Gastroenterology, Department of Medicine, Vanderbilt University, Nashville, TN 37232 2279, USA
    Cancer Res 68:379-87. 2008
    ..In addition to defining factors that mediate H. pylori-induced cancer, these results provide insight into mechanisms that may regulate the development of other malignancies arising within the context of inflammatory states...
  41. ncbi request reprint Carcinogenesis of Helicobacter pylori
    Pelayo Correa
    Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Gastroenterology 133:659-72. 2007
    ....
  42. pmc Plasma selenium measurements in subjects from areas with contrasting gastric cancer risks in Colombia
    M Constanza Camargo
    Department of Medicine, School of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University, Nashville, Tennessee 37232 0253, USA
    Arch Med Res 39:443-51. 2008
    ..This pilot study aimed to determine and compare selenium status in two Colombian populations with different gastric cancer risks: a high-risk area in the volcanic region of the Andes Mountains and a low-risk area on the Pacific coast...
  43. doi request reprint Exploratory factor analysis of squamous cell carcinoma of the esophagus in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clínicas Facultad de Medicina, Montevideo, Uruguay
    Nutr Cancer 60:188-95. 2008
    ..Because diet represents a complex set of highly correlated exposures, dietary patterns could be more explicative of the etiology of squamous cell carcinoma of the esophagus than the traditional reductionist approach...
  44. ncbi request reprint Nutrient intake and risk of squamous cell carcinoma of the esophagus: a case-control study in Uruguay
    Eduardo De Stefani
    Grupo de Epidemiologia, Departamento de Anatomia Patologica, Hospital de Clinicas, Facultad de Medicina, Montevideo, Uruguay
    Nutr Cancer 56:149-57. 2006
    ..4 (95% confidence interval, CI = 1.2-1.6), whereas lycopene displayed a strong protective effect (OR = 0.7; 95% CI = 0.6-0.9). The possible role of these and other dietary constituents in esophageal carcinogenesis is discussed...
  45. pmc Helicobacter pylori genotyping and sequencing using paraffin-embedded biopsies from residents of colombian areas with contrasting gastric cancer risks
    Liviu A Sicinschi
    Division of Gastroenterology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Helicobacter 13:135-45. 2008
    ....
  46. ncbi request reprint IL1B polymorphisms and gastric cancer risk
    M Constanza Camargo
    Cancer Epidemiol Biomarkers Prev 16:635; author reply 635-6. 2007
  47. ncbi request reprint Re: Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions
    Robertino Mera
    J Natl Cancer Inst 98:1426. 2006
  48. pmc Genomic changes during chronic Helicobacter pylori infection
    Christian Kraft
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Bacteriol 188:249-54. 2006
    ..These results suggest that adaptation of H. pylori to the host individual may principally occur through sequence changes rather than loss or gain of genes...
  49. ncbi request reprint [Microsatellite instability and loss of heterozygosity in neoplastic and preneoplastic gastric lesions]
    Juan Carlos Roa
    Departamento de Patologia, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 131:1227-36. 2003
    ..7 per 105 in males in the IX region. A chain of genetic and morphological events precedes the intestinal type of gastric carcinoma. One of them is the called multifocal atrophic gastritis often associated with intestinal metaplasia...
  50. ncbi request reprint Impact of Helicobacter pylori infection on growth of children: a prospective cohort study
    Luis Eduardo Bravo
    Department of Pathology, Universidad del Valle, Cali, Colombia
    J Pediatr Gastroenterol Nutr 37:614-9. 2003
    ....
  51. ncbi request reprint Determinants of Helicobacter pylori seroprevalence in Mexican adolescents
    M Constanza Camargo
    Center for Population Health Research, National Institute of Public Health, Cuernauaca, Mexico
    Helicobacter 9:106-14. 2004
    ..In this study we determined the H. pylori seroprevalence among adolescents in Morelos, Mexico, and explored the association between seroprevalence and socioeconomic, dietary and lifestyle variables...
  52. ncbi request reprint Increased reflux symptoms after calcium carbonate supplementation and successful anti-Helicobacter pylori treatment
    Lori A Fischbach
    School of Public Health, University of Texas, Dallas Regional Campus, Dallas, Texas, USA
    Dig Dis Sci 48:1487-94. 2003
    ..0001). Therefore, the interaction of calcium carbonate use, chronic multifocal atrophic gastritis, and the absence of Helicobacter pylori may increase reflux symptoms...
  53. ncbi request reprint Role and limitations of epidemiology in establishing a causal association
    Eduardo L Franco
    Department of Epidemiology, McGill University, 546 Pine Avenue West, Montreal, QC, Canada H2W1S6
    Semin Cancer Biol 14:413-26. 2004
    ..Both examples serve as paradigms of successful cooperation between epidemiologists and laboratory scientists in the pursuit of the understanding of cancer etiology...
  54. ncbi request reprint Squamous and small cell carcinomas of the lung: similarities and differences concerning the role of tobacco smoking
    Eduardo De Stefani
    Registro Nacional de Cancer, Avenida Brasil 3080 dep 402, Montevideo, Uruguay
    Lung Cancer 47:1-8. 2005
    ..These results suggests that SCLC display the strongest relation with tobacco smoking than SCC...
  55. ncbi request reprint MUC1 polymorphism confers increased risk for intestinal metaplasia in a Colombian population with chronic gastritis
    Filipe Silva
    1Institute of Molecular Pathology and Immunology of the University of Porto, IPATIMUP, Porto, Portugal
    Eur J Hum Genet 11:380-4. 2003
    ..Our study also shows that small MUC1 genotypes are associated with increased risk for IM development in Colombian patients...
  56. ncbi request reprint Microsatellite instability in preneoplastic and neoplastic lesions of the gallbladder
    Juan Carlos Roa
    Department of Pathology, Universidad de La Frontera, Faculty of Medicine, Manuel Montt 112, Temuco, Chile
    J Gastroenterol 40:79-86. 2005
    ..Our findings were then correlated with clinicopathological variables and survival time...
  57. ncbi request reprint Cytokine polymorphisms and gastric cancer risk: an evolving view
    Barbara G Schneider
    Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    Cancer Biol Ther 7:157-62. 2008
    ..In this review, we discuss challenges in experimental design of gene association studies in gastric cancer, with attention to gene-environment interactions that may lead to inconsistency in findings across populations...
  58. ncbi request reprint The role of vegetable and fruit consumption in the aetiology of squamous cell carcinoma of the oesophagus: a case-control study in Uruguay
    Eduardo De Stefani
    Departamento de Patologia, Instituto Nacional de Oncologia, Montevideo, Uruguay
    Int J Cancer 116:130-5. 2005
    ..47, 95% CI 0.34-0.67). The results of our study point towards an important role of fruits in the prevention of squamous cell carcinoma of the oesophagus...
  59. ncbi request reprint Histopathology of gastritis in Helicobacter pylori-infected children from populations at high and low gastric cancer risk
    Alvaro Bedoya
    Hospital Infantil, Pasto, Colombia
    Hum Pathol 34:206-13. 2003
    ..B lymphocytes were relatively more abundant in the lower-risk population. The possibility that the aforementioned characteristics of H. pylori infection in children are related to cancer risk in adults is discussed...
  60. ncbi request reprint Intestinal helminthiasis in Colombian children promotes a Th2 response to Helicobacter pylori: possible implications for gastric carcinogenesis
    Mark T Whary
    Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Building 16 825A, Cambridge, Massachusetts 02139, USA
    Cancer Epidemiol Biomarkers Prev 14:1464-9. 2005
    ..Considering the risk for H. pylori disease seems affected by features of bacterial virulence and host polymorphisms, other poorly understood influences, such as concurrent helminthiasis, may also be important...
  61. ncbi request reprint Virulence-associated genotypes of Helicobacter pylori: do they explain the African enigma?
    Luis E Bravo
    Department of Pathology, Universidad del Valle, Cali, Columbia
    Am J Gastroenterol 97:2839-42. 2002
    ..The aim of this study was to compare the distribution of virulence-associated genotypes of Helicobacter pylori in two Colombian populations with contrasting gastric cancer risk but with similar H. pylori infection prevalence...
  62. ncbi request reprint Delayed rise in incidence of gastric cancer in females results in unique sex ratio (M/F) pattern: etiologic hypothesis
    Pentti Sipponen
    Department of Pathology, HUCH Jorvi Hospital, 02740 Espoo, Finland
    Gastric Cancer 5:213-9. 2002
    ..The age-standardized and cumulative incidence rates of gastric cancer (GCA) are twice as high in males as in females...
  63. ncbi request reprint Antioxidant supplements for prevention of gastrointestinal cancers
    Pelayo Correa
    Lancet 365:470; author reply 471-2. 2005
  64. ncbi request reprint Supraglottic and glottic carcinomas: epidemiologically distinct entities?
    Eduardo De Stefani
    Registro Nacional de Cancer, Montevideo, Uruguay
    Int J Cancer 112:1065-71. 2004
    ..It could be suggested that concerning tobacco and alcohol effects, supraglottic and glottic squamous cell cancers are probably distinct epidemiologic entities...
  65. ncbi request reprint Dietary patterns and risk of gastric cancer: a case-control study in Uruguay
    Eduardo De Stefani
    Registro Nacional de Cancer, Avenida Brasil 3080 dep 402, Montevideo, Uruguay
    Gastric Cancer 7:211-20. 2004
    ..For this purpose, we included 240 cases and 960 controls...
  66. ncbi request reprint Dietary patterns and risk of cancer of the oral cavity and pharynx in Uruguay
    Eduardo De Stefani
    Departamento de Patologia, Instituto Nacional de Oncologia, Montevideo, Uruguay
    Nutr Cancer 51:132-9. 2005
    ..0 (95% CI, 4.1-34.6). Our study confirms the important role of dietary factors in oral and pharyngeal cancer risk and suggests that the analysis of dietary patterns is a powerful tool to investigate the links between nutrition and cancer...
  67. ncbi request reprint Functional adaptation of BabA, the H. pylori ABO blood group antigen binding adhesin
    Marina Aspholm-Hurtig
    Department of Odontology, Section of Oral Microbiology, Umea University, SE 901 87 Umea, Sweden
    Science 305:519-22. 2004
    ....
  68. ncbi request reprint Alcohol intake and risk of adenocarcinoma of the lung. A case-control study in Uruguay
    Eduardo De Stefani
    Registro Nacional de Cancer, Montevideo, Uruguay
    Lung Cancer 38:9-14. 2002
    ..These findings suggest that wine drinking has a protective effect in adenocarcinoma of the lung, whereas hard liquor increases moderately the risk of this cell type of lung cancer...