Andrew Catling

Summary

Affiliation: Louisiana State University Health Sciences Center
Country: USA

Publications

  1. pmc Epidermal growth factor stimulates extracellular-signal regulated kinase phosphorylation of a novel site on cytoplasmic Dynein intermediate chain 2
    Ashok K Pullikuth
    Department of Pharmacology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Int J Mol Sci 14:3595-620. 2013
  2. pmc Differential requirement for MEK Partner 1 in DU145 prostate cancer cell migration
    Electa R Park
    Department of Pharmacology, LSU Health Sciences Center New Orleans, LA, USA
    Cell Commun Signal 7:26. 2009
  3. pmc The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals
    Ashok Pullikuth
    Department of Pharmacology, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Mol Cell Biol 25:5119-33. 2005
  4. pmc Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation
    Mourad Zerfaoui
    Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    J Immunol 185:1894-902. 2010
  5. pmc Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP
    Ashok K Pullikuth
    Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Mol Cell Biol 30:3233-48. 2010
  6. pmc Gonadal hormones modulate the potency of the disruptive effects of donepezil in male rats responding under a nonspatial operant learning and performance task
    Stuart T Leonard
    Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112 1393, USA
    Behav Pharmacol 21:121-34. 2010
  7. pmc Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective
    Ashok K Pullikuth
    Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Cell Signal 19:1621-32. 2007
  8. pmc MEK1 activation by PAK: a novel mechanism
    Electa R Park
    Department of Biochemistry, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Cell Signal 19:1488-96. 2007
  9. pmc Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion
    Scott T Eblen
    Department of Microbiology, School of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    Mol Cell Biol 24:2308-17. 2004
  10. pmc PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
    Jill K Slack-Davis
    Department of Microbiology, University of Virginia Health System, Charlottesville, VA 22908, USA
    J Cell Biol 162:281-91. 2003

Research Grants

  1. COMBINATORIAL SIGNALING THROUGH MEK1
    Andrew Catling; Fiscal Year: 2009

Collaborators

Detail Information

Publications11

  1. pmc Epidermal growth factor stimulates extracellular-signal regulated kinase phosphorylation of a novel site on cytoplasmic Dynein intermediate chain 2
    Ashok K Pullikuth
    Department of Pharmacology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Int J Mol Sci 14:3595-620. 2013
    ..These data suggest that ERK phosphorylation of IC-2 regulates dynein function through mechanisms other than its interaction with dynactin...
  2. pmc Differential requirement for MEK Partner 1 in DU145 prostate cancer cell migration
    Electa R Park
    Department of Pharmacology, LSU Health Sciences Center New Orleans, LA, USA
    Cell Commun Signal 7:26. 2009
    ..MP1 may function by regulating the stability or expression of paxillin, a key regulator of motility...
  3. pmc The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals
    Ashok Pullikuth
    Department of Pharmacology, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Mol Cell Biol 25:5119-33. 2005
    ....
  4. pmc Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation
    Mourad Zerfaoui
    Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    J Immunol 185:1894-902. 2010
    ..These results provide novel insights into the mechanism by which PARP-1 promotes NF-kappaB nuclear retention, which ultimately can influence NF-kappaB-dependent gene regulation...
  5. pmc Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP
    Ashok K Pullikuth
    Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Mol Cell Biol 30:3233-48. 2010
    ..These observations reveal a novel role for ERK signaling in adhesion assembly in addition to its established role in adhesion disassembly...
  6. pmc Gonadal hormones modulate the potency of the disruptive effects of donepezil in male rats responding under a nonspatial operant learning and performance task
    Stuart T Leonard
    Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112 1393, USA
    Behav Pharmacol 21:121-34. 2010
    ....
  7. pmc Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective
    Ashok K Pullikuth
    Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA
    Cell Signal 19:1621-32. 2007
    ..Here we review data supporting the view that localized ERK signaling mediated through recently identified scaffold proteins may regulate cell migration...
  8. pmc MEK1 activation by PAK: a novel mechanism
    Electa R Park
    Department of Biochemistry, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Cell Signal 19:1488-96. 2007
    ....
  9. pmc Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion
    Scott T Eblen
    Department of Microbiology, School of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    Mol Cell Biol 24:2308-17. 2004
    ..We propose that activation of ERK during adhesion creates a feedback system in which ERK phosphorylates MEK1 on T292, and this in turn blocks additional S298 phosphorylation in response to integrin signaling...
  10. pmc PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
    Jill K Slack-Davis
    Department of Microbiology, University of Virginia Health System, Charlottesville, VA 22908, USA
    J Cell Biol 162:281-91. 2003
    ....
  11. pmc Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes
    Scott T Eblen
    Department of Microbiology, School of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    Mol Cell Biol 22:6023-33. 2002
    ..These findings reveal a novel mechanism by which adhesion and growth factor signals are integrated during ERK activation...

Research Grants9

  1. COMBINATORIAL SIGNALING THROUGH MEK1
    Andrew Catling; Fiscal Year: 2009
    ..These studies have the potential to reveal a universal mechanism by which MEK1 senses both adhesion and growth factor signals to regulate directional cell motility. ..