John S Torday
Affiliation: Los Angeles Biomedical Research Institute
- Torday J, Miller W. Phenotype as Agent for Epigenetic Inheritance. Biology (Basel). 2016;5: pubmed publisher..Furthermore, as first principles of physiology determine the limits of epigenetic inheritance, a coherent justification can thereby be provided for the obligate return of all multicellular eukaryotes to the unicellular state. ..
- Torday J, Rehan V. Up-regulation of fetal rat lung parathyroid hormone-related protein gene regulatory network down-regulates the Sonic Hedgehog/Wnt/betacatenin gene regulatory network. Pediatr Res. 2006;60:382-8 pubmed..This is the first evidence that alveolar fluid distension is an organizing principle for PTHrP signaling down-regulation of the Shh/Wnt/betacatenin pathway. ..
- TORDAY J, Rehan V. A cell-molecular approach predicts vertebrate evolution. Mol Biol Evol. 2011;28:2973-81 pubmed publisher..As a result, it predicts how cell-molecular changes in this process can cause disease and offers counterintuitive insights to diagnosis and treatment based on evolutionary principles. ..
- Torday J, Rehan V. Neutral lipid trafficking regulates alveolar type II cell surfactant phospholipid and surfactant protein expression. Exp Lung Res. 2011;37:376-86 pubmed publisher..The authors propose, therefore, that ADRP is the physiologic determinant for the elusive coordinated, stoichiometric synthesis of surfactant phospholipid and protein by pulmonary ATII cells. ..
- Torday J, Miller W. The resolution of ambiguity as the basis for life: A cellular bridge between Western reductionism and Eastern holism. Prog Biophys Mol Biol. 2017;131:288-297 pubmed publisher..Viewing the life circumstance in this manner permits a reasoned unification between Western rational reductionism and Eastern holism. ..
- Tozzi A, Peters J, Chafin C, De Falco D, Torday J. A timeless biology. Prog Biophys Mol Biol. 2018;134:38-43 pubmed publisher..We discuss the implications in biology: when assessing living beings, the underrated role of isolated "spatial" modifications needs to be emphasized, living apart the evolutionary role of time. ..