Judith Mourant

Summary

Affiliation: Los Alamos National Laboratory
Country: USA

Publications

  1. ncbi request reprint Angular dependent light scattering from multicellular spheroids
    J R Mourant
    Los Alamos National Laboratory, Bioscience Division, Los Alamos, New Mexico 87545, USA
    J Biomed Opt 7:93-9. 2002
  2. ncbi request reprint In vivo light scattering measurements for detection of precancerous conditions of the cervix
    Judith R Mourant
    Bioscience Division, Los Alamos National Laboratory, PO Box 1663, MS E535, Los Alamos, NM 87545, USA
    Gynecol Oncol 105:439-45. 2007
  3. ncbi request reprint Comparison of vibrational spectroscopy to biochemical and flow cytometry methods for analysis of the basic biochemical composition of mammalian cells
    Judith R Mourant
    Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA
    J Biomed Opt 11:064024. 2006
  4. ncbi request reprint Vibrational spectroscopy for identification of biochemical changes accompanying carcinogenesis and the formation of necrosis
    Judith Mourant
    Bioscience Division, Los Alamos National Laboratory, MSE535, Los Alamos, NM 87545, USA
    Gynecol Oncol 99:S58-60. 2005
  5. ncbi request reprint Biochemical differences in tumorigenic and nontumorigenic cells measured by Raman and infrared spectroscopy
    Judith R Mourant
    Los Alamos National Laboratory, MS E535, Bioscience Division, Los Alamos, New Mexico 87544, USA
    J Biomed Opt 10:031106. 2005
  6. pmc FTIR spectroscopy demonstrates biochemical differences in mammalian cell cultures at different growth stages
    J R Mourant
    Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA
    Biophys J 85:1938-47. 2003
  7. ncbi request reprint Polarized angular dependent spectroscopy of epithelial cells and epithelial cell nuclei to determine the size scale of scattering structures
    J R Mourant
    Los Alamos National Laboratory, Bioscience Division, Los Alamos, New Mexico 87545, USA
    J Biomed Opt 7:378-87. 2002
  8. pmc In vivo light scattering for the detection of cancerous and precancerous lesions of the cervix
    Judith R Mourant
    Bioscience Division, Los Alamos National Laboratory, P O Box 1663, MS E535, Los Alamos, New Mexico 87545, USA
    Appl Opt 48:D26-35. 2009
  9. pmc Raman spectroscopy detects biochemical changes due to proliferation in mammalian cell cultures
    Kurt W Short
    Bioscience Division, Los Alamos National Laboratory, NM 87545, USA
    Biophys J 88:4274-88. 2005
  10. ncbi request reprint Methods for measuring the infrared spectra of biological cells
    Judith R Mourant
    Bioscience Division MS E535, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Phys Med Biol 48:243-57. 2003

Research Grants

Detail Information

Publications10

  1. ncbi request reprint Angular dependent light scattering from multicellular spheroids
    J R Mourant
    Los Alamos National Laboratory, Bioscience Division, Los Alamos, New Mexico 87545, USA
    J Biomed Opt 7:93-9. 2002
    ..The cause of the differences in light scattering are likely due to the nontumorigenic cells arresting in the G1 phase of the cell cycle, while the tumorigenic cells continue to proliferate...
  2. ncbi request reprint In vivo light scattering measurements for detection of precancerous conditions of the cervix
    Judith R Mourant
    Bioscience Division, Los Alamos National Laboratory, PO Box 1663, MS E535, Los Alamos, NM 87545, USA
    Gynecol Oncol 105:439-45. 2007
    ..To examine the utility of in vivo elastic light scattering measurements to diagnose high grade squamous interepithelial lesions (HSIL) of the cervix...
  3. ncbi request reprint Comparison of vibrational spectroscopy to biochemical and flow cytometry methods for analysis of the basic biochemical composition of mammalian cells
    Judith R Mourant
    Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA
    J Biomed Opt 11:064024. 2006
    ..These results demonstrate that vibrational spectroscopy can provide reliable estimates of the biochemical composition of mammalian cells...
  4. ncbi request reprint Vibrational spectroscopy for identification of biochemical changes accompanying carcinogenesis and the formation of necrosis
    Judith Mourant
    Bioscience Division, Los Alamos National Laboratory, MSE535, Los Alamos, NM 87545, USA
    Gynecol Oncol 99:S58-60. 2005
  5. ncbi request reprint Biochemical differences in tumorigenic and nontumorigenic cells measured by Raman and infrared spectroscopy
    Judith R Mourant
    Los Alamos National Laboratory, MS E535, Bioscience Division, Los Alamos, New Mexico 87544, USA
    J Biomed Opt 10:031106. 2005
    ..The smallness of the spectral changes associated with tumorgenicity may be due to the subtle nature of the oncogenic change in this system (a single mutant oncogene)...
  6. pmc FTIR spectroscopy demonstrates biochemical differences in mammalian cell cultures at different growth stages
    J R Mourant
    Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA
    Biophys J 85:1938-47. 2003
    ....
  7. ncbi request reprint Polarized angular dependent spectroscopy of epithelial cells and epithelial cell nuclei to determine the size scale of scattering structures
    J R Mourant
    Los Alamos National Laboratory, Bioscience Division, Los Alamos, New Mexico 87545, USA
    J Biomed Opt 7:378-87. 2002
    ..Light scattering is likely sensitive to structures smaller than those commonly investigated by standard pathology methods...
  8. pmc In vivo light scattering for the detection of cancerous and precancerous lesions of the cervix
    Judith R Mourant
    Bioscience Division, Los Alamos National Laboratory, P O Box 1663, MS E535, Los Alamos, New Mexico 87545, USA
    Appl Opt 48:D26-35. 2009
    ..Furthermore, the robustness of the optical system for use by different doctors and to changes in fiber-optic probe are also assessed, and potential improvements in the optical system are discussed...
  9. pmc Raman spectroscopy detects biochemical changes due to proliferation in mammalian cell cultures
    Kurt W Short
    Bioscience Division, Los Alamos National Laboratory, NM 87545, USA
    Biophys J 88:4274-88. 2005
    ..Finally, the lipid/DNA ratio decreases for tumorigenic exponential nuclei. This knowledge will be important for Raman detection of rapidly dividing populations of cancer cells in vivo...
  10. ncbi request reprint Methods for measuring the infrared spectra of biological cells
    Judith R Mourant
    Bioscience Division MS E535, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Phys Med Biol 48:243-57. 2003
    ....

Research Grants20

  1. Light scattering and normal tissue models
    Judith R Mourant; Fiscal Year: 2010
    ....
  2. RAMAN SPECTROSCOPY FOR CANCER DIAGNOSIS AND MONITORING
    Judith Mourant; Fiscal Year: 2005
    ..Consequently, treatments could be customized. ..
  3. Interdisciplinary researchers to address biomedical optics challenges, BIOMED 06
    Judith Mourant; Fiscal Year: 2006
    ....
  4. Light scattering and normal tissue models
    Judith Mourant; Fiscal Year: 2005
    ..ASCUS is the most common anomaly detected by Pan smears and annual follow up is estimated to cost 4.5 billion dollars per year. ..
  5. LIGHT SCATTERING IN TUMOR AND NORMAL TISSUE MODELS
    Judith Mourant; Fiscal Year: 2000
    ....