Peter Hraber

Summary

Affiliation: Los Alamos National Laboratory
Country: USA

Publications

  1. doi request reprint Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants
    Peter Hraber
    Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Viruses 7:5443-75. 2015
  2. pmc HIV-1 subtype C superinfected individuals mount low autologous neutralizing antibody responses prior to intrasubtype superinfection
    Debby Basu
    Immunology and Molecular Pathogenesis Graduate Program, Emory University, Atlanta, GA, USA
    Retrovirology 9:76. 2012
  3. pmc Timing and source of subtype-C HIV-1 superinfection in the newly infected partner of Zambian couples with disparate viruses
    Colleen S Kraft
    Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA
    Retrovirology 9:22. 2012
  4. pmc Classification of hepatitis C virus and human immunodeficiency virus-1 sequences with the branching index
    Peter Hraber
    Theoretical Biology and Biophysics, T 10 MS K710, LANL, Los Alamos, NM 87545, USA
    J Gen Virol 89:2098-107. 2008
  5. ncbi request reprint Evidence for human leukocyte antigen heterozygote advantage against hepatitis C virus infection
    Peter Hraber
    Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Hepatology 46:1713-21. 2007
  6. pmc Comparative analysis of hepatitis C virus phylogenies from coding and non-coding regions: the 5' untranslated region (UTR) fails to classify subtypes
    Peter T Hraber
    Theoretical Biology and Biophysics, T 10 MS K710, Los Alamos National Laboratory, Los Alamos NM 87545, USA
    Virol J 3:103. 2006
  7. pmc The hepatitis C sequence database in Los Alamos
    Carla Kuiken
    HCV database, Los Alamos National Laboratory, Los Alamos, NM, USA
    Nucleic Acids Res 36:D512-6. 2008
  8. ncbi request reprint Los Alamos hepatitis C virus sequence and human immunology databases: an expanding resource for antiviral research
    Peter T Hraber
    Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos NM, USA
    Antivir Chem Chemother 18:113-23. 2007
  9. pmc A multiple-alignment based primer design algorithm for genetically highly variable DNA targets
    Johanna Brodin
    Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    BMC Bioinformatics 14:255. 2013
  10. pmc Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies
    Peter Hraber
    Los Alamos National Laboratory, Los Alamos, New Mexico, USA
    J Virol 88:12623-43. 2014

Collaborators

Detail Information

Publications12

  1. doi request reprint Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants
    Peter Hraber
    Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Viruses 7:5443-75. 2015
    ....
  2. pmc HIV-1 subtype C superinfected individuals mount low autologous neutralizing antibody responses prior to intrasubtype superinfection
    Debby Basu
    Immunology and Molecular Pathogenesis Graduate Program, Emory University, Atlanta, GA, USA
    Retrovirology 9:76. 2012
    ..We hypothesized that this reflected a blunted NAb response, which may have made these individuals more susceptible to superinfection...
  3. pmc Timing and source of subtype-C HIV-1 superinfection in the newly infected partner of Zambian couples with disparate viruses
    Colleen S Kraft
    Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA
    Retrovirology 9:22. 2012
    ..We have, therefore, investigated the incidence and viral origin of superinfection in these couples...
  4. pmc Classification of hepatitis C virus and human immunodeficiency virus-1 sequences with the branching index
    Peter Hraber
    Theoretical Biology and Biophysics, T 10 MS K710, LANL, Los Alamos, NM 87545, USA
    J Gen Virol 89:2098-107. 2008
    ..In synthetic recombinants, regions without breakpoints are recognized accurately; regions with breakpoints do not represent any known subtype uniquely. Web-based services for viral subtype classification with the BI are available online...
  5. ncbi request reprint Evidence for human leukocyte antigen heterozygote advantage against hepatitis C virus infection
    Peter Hraber
    Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Hepatology 46:1713-21. 2007
    ..05 x 10(-6)) than as low-resolution genotypes (P = 1.99 x 10(-3)). No significant associations between zygosity and HCV infection were found for other HLA loci...
  6. pmc Comparative analysis of hepatitis C virus phylogenies from coding and non-coding regions: the 5' untranslated region (UTR) fails to classify subtypes
    Peter T Hraber
    Theoretical Biology and Biophysics, T 10 MS K710, Los Alamos National Laboratory, Los Alamos NM 87545, USA
    Virol J 3:103. 2006
    ..This study used the Shimodaira-Hasegawa test and related statistical techniques to compare phylogenetic trees obtained from coding and non-coding regions of a whole-genome alignment for the reliability of subtyping in different regions...
  7. pmc The hepatitis C sequence database in Los Alamos
    Carla Kuiken
    HCV database, Los Alamos National Laboratory, Los Alamos, NM, USA
    Nucleic Acids Res 36:D512-6. 2008
    ..The HCV website can be accessed via http://hcv.lanl.gov and http://hcv-db.org...
  8. ncbi request reprint Los Alamos hepatitis C virus sequence and human immunology databases: an expanding resource for antiviral research
    Peter T Hraber
    Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos NM, USA
    Antivir Chem Chemother 18:113-23. 2007
    ..This paper describes the types of data and the services that these databases offer, the tools they provide, and their configuration and use. Examples of applications to clonal analysis for drug-resistance mutations are shown...
  9. pmc A multiple-alignment based primer design algorithm for genetically highly variable DNA targets
    Johanna Brodin
    Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    BMC Bioinformatics 14:255. 2013
    ....
  10. pmc Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies
    Peter Hraber
    Los Alamos National Laboratory, Los Alamos, New Mexico, USA
    J Virol 88:12623-43. 2014
    ..These findings highlight important considerations for the design and testing of candidate HIV-1 vaccines that aim to elicit effective nAbs...
  11. pmc Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing
    Will Fischer
    Theoretical Biology, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
    PLoS ONE 5:e12303. 2010
    ..Dramatic shifts in the frequencies of epitope variants during the first weeks of infection revealed a complex interplay between viral fitness and immune escape...
  12. ncbi request reprint Advantage of rare HLA supertype in HIV disease progression
    Elizabeth Trachtenberg
    Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way Oakland, California 94609, USA
    Nat Med 9:928-35. 2003
    ..The correlation of the frequency of the HLA supertypes with viral load suggests that HIV adapts to the most frequent alleles in the population, providing a selective advantage for those individuals who express rare alleles...