J E Hansen

Summary

Affiliation: Los Angeles Biomedical Research Institute
Country: USA

Publications

  1. ncbi request reprint Gas exchange detection of exercise-induced right-to-left shunt in patients with primary pulmonary hypertension
    Xing Guo Sun
    Department of Medicine, Harbor UCLA Medical Center, Torrance, Calif 90509 2910, USA
    Circulation 105:54-60. 2002
  2. ncbi request reprint Mixed-expired and end-tidal CO2 distinguish between ventilation and perfusion defects during exercise testing in patients with lung and heart diseases
    James E Hansen
    Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, 1000 W Carson St, RB 2, Box 405, Torrance CA 90509, USA
    Chest 132:977-83. 2007
  3. doi request reprint Oscillatory breathing and exercise gas exchange abnormalities prognosticate early mortality and morbidity in heart failure
    Xing Guo Sun
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 West Carson Street, Torrance, CA 90502, USA
    J Am Coll Cardiol 55:1814-23. 2010
  4. pmc A simple new visualization of exercise data discloses pathophysiology and severity of heart failure
    James E Hansen
    St John s Cardiovascular Research Center, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Division of Respiratory Physiology and Medicine, Department of Medicine, University of California at Los Angeles David Geffen School of Medicine Torrance, CA
    J Am Heart Assoc 1:e001883. 2012
  5. doi request reprint Calculating gambling odds and lung ages for smokers
    J E Hansen
    Los Angeles Biomedical Research Institute and Division of Respiratory and Critical Care Physiology and Medicine, Dept of Medicine at Harbor UCLA Medical Center, University of California David Geffen School of Medicine, Torrance, CA, USA
    Eur Respir J 35:776-80. 2010
  6. doi request reprint Argument for changing criteria for bronchodilator responsiveness
    James E Hansen
    Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
    Respir Med 102:1777-83. 2008
  7. ncbi request reprint Spirometric criteria for airway obstruction: Use percentage of FEV1/FVC ratio below the fifth percentile, not < 70%
    James E Hansen
    Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90509
    Chest 131:349-55. 2007
  8. ncbi request reprint A perspective on tuberculosis & exercise testing
    James E Hansen
    UCLA School of Medicine, Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Harbor UCLA Medical Center Torrance, CA 90509, USA
    Indian J Med Res 124:383-4. 2006
  9. ncbi request reprint Ethnic- and sex-free formulae for detection of airway obstruction
    James E Hansen
    Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Los Angeles Biomedical Institute at Harbor UCLA Medical Center, Torrance, CA 90509, USA
    Am J Respir Crit Care Med 174:493-8. 2006
  10. ncbi request reprint Discriminating measures and normal values for expiratory obstruction
    James E Hansen
    Department of Respiratory and Critical Care Physiology and Medicine, Harbor UCLA Medical Center, Torrance, CA 90509, USA
    Chest 129:369-77. 2006

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Gas exchange detection of exercise-induced right-to-left shunt in patients with primary pulmonary hypertension
    Xing Guo Sun
    Department of Medicine, Harbor UCLA Medical Center, Torrance, Calif 90509 2910, USA
    Circulation 105:54-60. 2002
    ..This article first hypothesizes and then describes unique changes in gas exchange when right-to-left exercise-induced shunting (EIS) occurs...
  2. ncbi request reprint Mixed-expired and end-tidal CO2 distinguish between ventilation and perfusion defects during exercise testing in patients with lung and heart diseases
    James E Hansen
    Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, 1000 W Carson St, RB 2, Box 405, Torrance CA 90509, USA
    Chest 132:977-83. 2007
    ....
  3. doi request reprint Oscillatory breathing and exercise gas exchange abnormalities prognosticate early mortality and morbidity in heart failure
    Xing Guo Sun
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 West Carson Street, Torrance, CA 90502, USA
    J Am Coll Cardiol 55:1814-23. 2010
    ..Potential predictors, derived from cardiopulmonary exercise testing, were compared with other commonly used cardiovascular measurements...
  4. pmc A simple new visualization of exercise data discloses pathophysiology and severity of heart failure
    James E Hansen
    St John s Cardiovascular Research Center, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Division of Respiratory Physiology and Medicine, Department of Medicine, University of California at Los Angeles David Geffen School of Medicine Torrance, CA
    J Am Heart Assoc 1:e001883. 2012
    ..The complexity of cardiopulmonary exercise testing data and their displays tends to make assessment of patients, including those with heart failure, time consuming...
  5. doi request reprint Calculating gambling odds and lung ages for smokers
    J E Hansen
    Los Angeles Biomedical Research Institute and Division of Respiratory and Critical Care Physiology and Medicine, Dept of Medicine at Harbor UCLA Medical Center, University of California David Geffen School of Medicine, Torrance, CA, USA
    Eur Respir J 35:776-80. 2010
    ..Using odds and Deltalung ages rather than traditional 95% confidence limits might better persuade smokers to quit...
  6. doi request reprint Argument for changing criteria for bronchodilator responsiveness
    James E Hansen
    Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
    Respir Med 102:1777-83. 2008
    ..We hypothesized that BD responsiveness was better assessed using a statistical approach, linked to each individual's spirometric measurements, rather than the variability of others...
  7. ncbi request reprint Spirometric criteria for airway obstruction: Use percentage of FEV1/FVC ratio below the fifth percentile, not < 70%
    James E Hansen
    Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90509
    Chest 131:349-55. 2007
    ....
  8. ncbi request reprint A perspective on tuberculosis & exercise testing
    James E Hansen
    UCLA School of Medicine, Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Harbor UCLA Medical Center Torrance, CA 90509, USA
    Indian J Med Res 124:383-4. 2006
  9. ncbi request reprint Ethnic- and sex-free formulae for detection of airway obstruction
    James E Hansen
    Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Los Angeles Biomedical Institute at Harbor UCLA Medical Center, Torrance, CA 90509, USA
    Am J Respir Crit Care Med 174:493-8. 2006
    ....
  10. ncbi request reprint Discriminating measures and normal values for expiratory obstruction
    James E Hansen
    Department of Respiratory and Critical Care Physiology and Medicine, Harbor UCLA Medical Center, Torrance, CA 90509, USA
    Chest 129:369-77. 2006
    ....
  11. ncbi request reprint Should forced expiratory volume in six seconds replace forced vital capacity to detect airway obstruction?
    J E Hansen
    Harbor UCLA Medical Center, Box 405, 1000 W Carson Street, Torrance, CA 90509, USA
    Eur Respir J 27:1244-50. 2006
    ....
  12. ncbi request reprint A noninvasive assessment of pulmonary perfusion abnormality in patients with primary pulmonary hypertension
    H Ting
    Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Harbor-UCLA Medical Center, Torrance, CA, USA
    Chest 119:824-32. 2001
    ..Further studies are needed to elucidate whether noninvasive gas exchange measurements may be clinically useful in the evaluation of the severity of pulmonary vascular disease and the effectiveness of pulmonary vasodilator therapy...
  13. ncbi request reprint Carbon dioxide pressure-concentration relationship in arterial and mixed venous blood during exercise
    X G Sun
    Division of Respiratory and Critical Care Physiology and Medicine, Harbor-University of California Los Angeles Medical Center, Torrance 90509-2910, USA
    J Appl Physiol 90:1798-810. 2001
    ..4 to 15.2 mM. We conclude that changes in buffer base and pH dominate the PCO(2)-CCO(2) relationship during exercise, with changes in Hb and blood oxyhemoglobin saturation exerting much less influence...
  14. ncbi request reprint End-tidal PCO2 abnormality and exercise limitation in patients with primary pulmonary hypertension
    Yuji Yasunobu
    Department of Medicine, Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, Torrance, CA 90509 2910, USA
    Chest 127:1637-46. 2005
    ..Our aim was to determine the size of the reduction in end-tidal Pco(2) (Petco(2)) as a reflection of the abnormality in ventilatory efficiency and ventilatory drive in PPH patients...
  15. ncbi request reprint Reproducibility of cardiopulmonary exercise measurements in patients with pulmonary arterial hypertension
    James E Hansen
    Department of Medicine, Harbor UCLA Medical Center, Torrance, CA 90509, USA
    Chest 126:816-24. 2004
    ..Setting and patients: Over a 15-month period at two tertiary-care teaching hospitals, 42 patients with PAH underwent repeated, paired CPETs using cycle ergometry...
  16. pmc Usefulness of right-to-left shunting and poor exercise gas exchange for predicting prognosis in patients with pulmonary arterial hypertension
    Ronald J Oudiz
    Department of Medicine, Division of Cardiology, Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, Torrance, CA, USA
    Am J Cardiol 105:1186-91. 2010
    ..In conclusion, a persistent exercise-induced right-to-left shunt and poor ventilatory efficiency were highly predictive of poor outcomes in patients with pulmonary arterial hypertension...
  17. ncbi request reprint Effect of biventricular pacing on the exercise pathophysiology of heart failure
    Karlman Wasserman
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 W Carson St, Torrance, CA 90502, USA
    Chest 132:250-61. 2007
    ..Biventricular pacing (BVP) is used for cardiac resynchronization therapy in wide-QRS-complex heart failure. We sought to quantify the effect of BVP on the exercise pathophysiology of heart failure patients...
  18. ncbi request reprint Ventilatory efficiency during exercise in healthy subjects
    Xing Guo Sun
    Division of Respiratory and Critical Care Physiology and Medicine, Research and Education Institute, Harbor UCLA Medical Center, St John s Cardiovascular Research Center, Torrance, California 90509, USA
    Am J Respir Crit Care Med 166:1443-8. 2002
    ..94 + 0.108 x age + (0.97 = F, 0.0 = M) - 0.0376 x height, where age is in years and height is in centimeters. We conclude that the lowest VE/CO2 output ratio is the preferred noninvasive method to estimate ventilatory inefficiency...
  19. ncbi request reprint Cardiopulmonary exercise testing and six-minute walk correlations in pulmonary arterial hypertension
    Ronald J Oudiz
    Saint John s Cardiovascular Research Center, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California, USA
    Am J Cardiol 97:123-6. 2006
    ..Weight adjustment of the 6MW improved its correlation with peak VO2. In conclusion, in future multicenter trials, CPET expertise should be validated at all sites before subject enrollment...
  20. ncbi request reprint Exercise pathophysiology in patients with primary pulmonary hypertension
    X G Sun
    Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA
    Circulation 104:429-35. 2001
    ..CONCLUSIONS: Patients with PPH can safely undergo noninvasive cycle ergometer CPET to their maximal tolerance. The CPET abnormalities were consistent and characteristic and correlated well with NYHA class...
  21. ncbi request reprint Ethnic differences in pulmonary function in healthy nonsmoking Asian-Americans and European-Americans
    B Korotzer
    Division of Respiratory and Critical Care Physiology and Medicine, Harbor UCLA Medical Center, Torrance, California 90509, USA
    Am J Respir Crit Care Med 161:1101-8. 2000
    ..Ethnic differences between individuals of Asian and European backgrounds should be considered when interpreting pulmonary function tests, especially when predicted values are based on populations of European descent...
  22. ncbi request reprint Pulmonary function in primary pulmonary hypertension
    Xing Guo Sun
    Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Research and Education Institute, Harbor UCLA Medical Center, Torrance, CA 90509, USA
    J Am Coll Cardiol 41:1028-35. 2003
    ..The study was done to ascertain the degree to which abnormalities in resting lung function correlate with the disease severity of patients with primary pulmonary hypertension (PPH)...
  23. pmc Effect of sildenafil on ventilatory efficiency and exercise tolerance in pulmonary hypertension
    Ronald J Oudiz
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA, USA
    Eur J Heart Fail 9:917-21. 2007
    ..The pulmonary vasculopathy in pulmonary arterial hypertension (PAH) results in increased resistance to pulmonary blood flow, limiting the cardiac output required for the increased O(2) demands of exercise...
  24. ncbi request reprint Muscle deoxygenation as related to work rate
    Ming Lung Chuang
    Division of Respiratory and Critical Care Physiology and Medicine, Department of Medicine, Harbor UCLA Medical Center, Torrance, CA 90509, USA
    Med Sci Sports Exerc 34:1614-23. 2002
    ..We hypothesized that similar differences, with respect to the LAT, will be observed in muscle deoxygenation kinetics when studied with near-infrared spectroscopy (NIRS)...
  25. ncbi request reprint Sarcoidosis and gas exchange measures
    James E Hansen
    Chest 121:1004-5. 2002