Matthew Jay Budoff

Summary

Affiliation: Los Angeles Biomedical Research Institute
Country: USA

Publications

  1. ncbi request reprint Point: Diabetic Patients and Coronary Calcium: Risk stratification, compliance, and plaque progression
    Matthew J Budoff
    Division of Cardiology, Saint John s Cardiovascular Research Center, Research and Education Institute at Harbor UCLA Medical Center, Torrance, California 90502, USA
    Diabetes Care 26:541-2. 2003
  2. doi request reprint Comparison of transesophageal echocardiography versus computed tomography for detection of left atrial appendage filling defect (thrombus)
    Matthew J Budoff
    Department of Internal Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California Electronic address
    Am J Cardiol 113:173-7. 2014
  3. pmc Particulate matter components and subclinical atherosclerosis: common approaches to estimating exposure in a Multi-Ethnic Study of Atherosclerosis cross-sectional study
    Min Sun
    Department of Environmental and Occupational Health Sciences, University of Washington School of Public Health, 4225 Roosevelt Way NE, 100, Seattle, WA, 98105, USA
    Environ Health 12:39. 2013
  4. pmc An alternative method for quantifying coronary artery calcification: the multi-ethnic study of atherosclerosis (MESA)
    C Jason Liang
    Department of Biostatistics, University of Washington, Seattle, WA, USA
    BMC Med Imaging 12:14. 2012
  5. pmc Genetics of coronary artery calcification among African Americans, a meta-analysis
    Mary K Wojczynski
    Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA
    BMC Med Genet 14:75. 2013
  6. pmc A comparison of outcomes with coronary artery calcium scanning in unselected populations: the Multi-Ethnic Study of Atherosclerosis (MESA) and Heinz Nixdorf RECALL study (HNR)
    Matthew J Budoff
    Los Angeles Biomedical Research Center, 1124 W Carson St, Torrance, CA 90502, USA
    J Cardiovasc Comput Tomogr 7:182-91. 2013
  7. doi request reprint Measurement of phantomless thoracic bone mineral density on coronary artery calcium CT scans acquired with various CT scanner models
    Matthew J Budoff
    Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, 1124 W Carson St, Torrance, CA 90502 2006, USA
    Radiology 267:830-6. 2013
  8. doi request reprint Use of cardiovascular computed tomography in the diagnosis and management of coarctation of the aorta
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, Calif 90502, USA
    J Thorac Cardiovasc Surg 146:229-32. 2013
  9. doi request reprint Diagnostic accuracy of coronary artery calcium for obstructive disease: results from the ACCURACY trial
    Matthew J Budoff
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA, USA
    Int J Cardiol 166:505-8. 2013
  10. doi request reprint Updates on insulin resistance
    Matthew Budoff
    David Geffen School of Medicine at UCLA, Los Angeles Biomedical Research Institute, 1124 W Carson Street, RB2, Torrance, CA 90502, USA
    Expert Rev Cardiovasc Ther 11:283-4. 2013

Research Grants

Detail Information

Publications85

  1. ncbi request reprint Point: Diabetic Patients and Coronary Calcium: Risk stratification, compliance, and plaque progression
    Matthew J Budoff
    Division of Cardiology, Saint John s Cardiovascular Research Center, Research and Education Institute at Harbor UCLA Medical Center, Torrance, California 90502, USA
    Diabetes Care 26:541-2. 2003
  2. doi request reprint Comparison of transesophageal echocardiography versus computed tomography for detection of left atrial appendage filling defect (thrombus)
    Matthew J Budoff
    Department of Internal Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California Electronic address
    Am J Cardiol 113:173-7. 2014
    ..242) improves accuracy of positively detecting LAA thrombus. This technique is especially useful when delayed scanning is not performed and LAA is found incidentally after the patient scanning is complete...
  3. pmc Particulate matter components and subclinical atherosclerosis: common approaches to estimating exposure in a Multi-Ethnic Study of Atherosclerosis cross-sectional study
    Min Sun
    Department of Environmental and Occupational Health Sciences, University of Washington School of Public Health, 4225 Roosevelt Way NE, 100, Seattle, WA, 98105, USA
    Environ Health 12:39. 2013
    ..Concentrations of outdoor fine particulate matter (PM2.5) have been associated with cardiovascular disease. PM2.5 chemical composition may be responsible for effects of exposure to PM2.5...
  4. pmc An alternative method for quantifying coronary artery calcification: the multi-ethnic study of atherosclerosis (MESA)
    C Jason Liang
    Department of Biostatistics, University of Washington, Seattle, WA, USA
    BMC Med Imaging 12:14. 2012
    ..We developed a semi-automated threshold-free scoring method, the spatially weighted calcium score (SWCS) for CAC in the Multi-Ethnic Study of Atherosclerosis (MESA)...
  5. pmc Genetics of coronary artery calcification among African Americans, a meta-analysis
    Mary K Wojczynski
    Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA
    BMC Med Genet 14:75. 2013
    ..African Americans (AA) have higher rates of CHD but are less well-studied in genomic studies. We assembled the largest AA data resource currently available with measured CAC to identify associated genetic variants...
  6. pmc A comparison of outcomes with coronary artery calcium scanning in unselected populations: the Multi-Ethnic Study of Atherosclerosis (MESA) and Heinz Nixdorf RECALL study (HNR)
    Matthew J Budoff
    Los Angeles Biomedical Research Center, 1124 W Carson St, Torrance, CA 90502, USA
    J Cardiovasc Comput Tomogr 7:182-91. 2013
    ....
  7. doi request reprint Measurement of phantomless thoracic bone mineral density on coronary artery calcium CT scans acquired with various CT scanner models
    Matthew J Budoff
    Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, 1124 W Carson St, Torrance, CA 90502 2006, USA
    Radiology 267:830-6. 2013
    ..To determine the accuracy and precision of thoracic phantomless bone mineral density (BMD) measurements obtained on coronary artery calcium (CAC) computed tomography (CT) scans by using a variety of commercially available CT scanners...
  8. doi request reprint Use of cardiovascular computed tomography in the diagnosis and management of coarctation of the aorta
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, Calif 90502, USA
    J Thorac Cardiovasc Surg 146:229-32. 2013
    ..We present various forms of coarctation of the aorta on cardiac computed tomography...
  9. doi request reprint Diagnostic accuracy of coronary artery calcium for obstructive disease: results from the ACCURACY trial
    Matthew J Budoff
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA, USA
    Int J Cardiol 166:505-8. 2013
    ..We evaluated the diagnostic accuracy of CAC by 64-row CT to detect obstructive coronary stenosis compared to quantitative coronary angiography (QCA) in the ACCURACY multicenter trial...
  10. doi request reprint Updates on insulin resistance
    Matthew Budoff
    David Geffen School of Medicine at UCLA, Los Angeles Biomedical Research Institute, 1124 W Carson Street, RB2, Torrance, CA 90502, USA
    Expert Rev Cardiovasc Ther 11:283-4. 2013
    ..In recent years, the Congress has advanced awareness of the contribution of multiple endocrine and paracrine systems to obesity, diabetes and cardiovascular disease...
  11. doi request reprint Trabecular bone mineral density measurement using thoracic and lumbar quantitative computed tomography
    Matthew J Budoff
    Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    Acad Radiol 19:179-83. 2012
    ..To evaluate the agreement of bone mineral density (BMD) between lumbar (L) and individual thoracic (T) vertebrae and identify a standard thoracic spine level for BMD assessment in cardiac computed tomography (CT) images...
  12. ncbi request reprint Triaging patients with acute chest pain in the emergency department: implications of the CT-STAT trial
    Jennifer M Malpeso
    Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, 1124 W Carson St, Torrance, CA 90502, USA
    Expert Rev Cardiovasc Ther 10:155-7. 2012
    ..CT-STAT is the first multicenter trial to demonstrate the power of coronary CTA to streamline patient care in the acute setting and radically transform current treatment algorithms...
  13. pmc Low fingertip temperature rebound measured by digital thermal monitoring strongly correlates with the presence and extent of coronary artery disease diagnosed by 64-slice multi-detector computed tomography
    Naser Ahmadi
    Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, Torrance, CA 90502, USA
    Int J Cardiovasc Imaging 25:725-38. 2009
    ..88 for the prediction of obstructive CAD. In patients suspected of CAD, low fingertip temperature rebound measured by DTM significantly predicted CTA-diagnosed obstructive disease...
  14. pmc Central aortic valve coaptation area during diastole as seen by 64-multidetector computed tomography (MDCT)
    Irfan Zeb
    Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    Int J Cardiovasc Imaging 26:947-51. 2010
    ..80, P ≤ 0.001). Central aortic valve coaptation area is a central area present at the coaptation of nodules of arantius of aortic cusps during diastole; it is incompetent and increased in size in patients with aortic regurgitation...
  15. pmc Validation of the severity index by cardiac catheterization and Doppler echocardiography in patients with aortic sclerosis and stenosis
    David M Shavelle
    Los Angeles BioMedical Research Institute at Harbor UCLA Research, Division of Cardiology, Torrance, CA, USA
    Cardiovasc Ultrasound 4:12. 2006
    ..0001; r = 0.84, p < 0.0001, respectively). These results confirm that the severity index correlates with hemodynamic severity of aortic valve disease and may prove to be a useful measure in patients with aortic sclerosis and AS...
  16. pmc Outcome of coronary plaque burden: a 10-year follow-up of aggressive medical management
    Victor K Goh
    Imaging Centre, Matilda International Hospital, 41 Mount Kellett Road, The Peak, Hong Kong, SAR China
    Cardiovasc Ultrasound 8:5. 2010
    ..The effect of aggressive medical therapy on quantitative coronary plaque burden is not generally known, especially in ethnic Chinese...
  17. ncbi request reprint Multiphase contrast medium injection for optimization of computed tomographic coronary angiography
    Matthew Jay Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    Acad Radiol 13:159-65. 2006
    ..We hypothesized that vascular image opacification and uniformity of vascular enhancement between slices can be improved using multiphase contrast medium injection protocols...
  18. ncbi request reprint Computed tomographic cardiovascular imaging
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    Semin Ultrasound CT MR 27:32-41. 2006
    ..g., non-invasive stress imaging) and intensification of medical therapy; CAC should have a significant impact on early detection and management of CAD...
  19. ncbi request reprint Long-term prognosis associated with coronary calcification: observations from a registry of 25,253 patients
    Matthew J Budoff
    Harbor UCLA Los Angeles Biomedical Research Institute, Torrance, California 90502, USA
    J Am Coll Cardiol 49:1860-70. 2007
    ....
  20. pmc Expert review on coronary calcium
    Matthew J Budoff
    Division of Cardiology, Saint John s Cardiovascular Research Center, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, California 90502, USA
    Vasc Health Risk Manag 4:315-24. 2008
    ..This article reviews information pertaining to the clinical use of CAC for assessing coronary atherosclerosis as a useful predictor of coronary artery disease (CAD) in certain population of patients...
  21. ncbi request reprint Coronary CT Angiography after Invasive Angiography: Is It Worth It?
    Matthew J Budoff
    Los Angeles Biomedical Research Institute at Harbor UCLA, 1124 W Carson Street, RB2, Torrance, CA, 90502, USA
    J Invasive Cardiol 20:7-8. 2008
  22. ncbi request reprint Cardiac CT angiography (CTA) and nuclear myocardial perfusion imaging (MPI)-a comparison in detecting significant coronary artery disease
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, 1124 W Carson Street, RB2, Torrance, CA 90502, USA
    Acad Radiol 14:252-7. 2007
    ..In this study, we sought to compare the accuracies of CTA and myocardial perfusion imaging (MPI) for identifying symptomatic patients with hemodynamically significant obstructive coronary artery disease (CAD)...
  23. ncbi request reprint Coronary calcium: does it still play a role in the age of CT angiography
    Matthew J Budoff
    Los Angeles Biomedical Research Institute at Harbor UCLA, 1124 W Carson Street, RB2 Torrance, CA, USA
    Expert Rev Cardiovasc Ther 5:1-3. 2007
  24. ncbi request reprint Cardiac computed tomography: diagnostic utility and integration in clinical practice
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California 90502, USA
    Clin Cardiol 29:I4-14. 2006
    ..This paper reviews the diagnostic utility and limitations of cardiac CT and how it could be integrated into clinical practice...
  25. ncbi request reprint Incidental findings with cardiac CT evaluation: should we read beyond the heart?
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA USA
    Catheter Cardiovasc Interv 68:965-73. 2006
    ..If a non-cardiac abnormality is visualized by the primary interpreter of the cardiac CT, appropriate referral or follow-up is prudent...
  26. ncbi request reprint Comparison of electron beam computed tomography and technetium stress testing in differentiating cause of dilated versus ischemic cardiomyopathy
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
    J Comput Assist Tomogr 29:699-703. 2005
    ..The diagnostic accuracy of nuclear stress testing and electron beam tomography (EBT) was evaluated to differentiate between nonischemic and ischemic CM, using coronary angiography as the reference standard...
  27. doi request reprint Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coro
    Matthew J Budoff
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, California, USA
    J Am Coll Cardiol 52:1724-32. 2008
    ..The purpose of this study was to evaluate the diagnostic accuracy of electrocardiographically gated 64-multidetector row coronary computed tomographic angiography (CCTA) in individuals without known coronary artery disease (CAD)...
  28. pmc Relationship of estimated GFR and coronary artery calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study
    Matthew J Budoff
    Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA, USA
    Am J Kidney Dis 58:519-26. 2011
    ..Although individuals with chronic kidney disease (CKD) are at markedly increased mortality risk, the incidence, prevalence, and prognosis of CAC in CKD are not well understood...
  29. pmc Coronary artery and thoracic calcium on noncontrast thoracic CT scans: comparison of ungated and gated examinations in patients from the COPD Gene cohort
    Matthew J Budoff
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 West Carson Street, Building RB2, Torrance, CA 90502, USA
    J Cardiovasc Comput Tomogr 5:113-8. 2011
    ..We sought to evaluate concordance of CAC and TAC scores on ungated (thoracic) and electrocardiogaphically (ECG)-gated (cardiac) MDCT scans...
  30. doi request reprint Progression of coronary artery calcium predicts all-cause mortality
    Matthew J Budoff
    Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, California 90502, USA
    JACC Cardiovasc Imaging 3:1229-36. 2010
    ..This study examined a large cohort to assess whether progression of coronary artery calcium (CAC) was associated with all-cause mortality, and which among 3 different methods to assess CAC progression provided the best estimate of risk...
  31. doi request reprint Cost-effectiveness of multidetector computed tomography compared with myocardial perfusion imaging as gatekeeper to invasive coronary angiography in asymptomatic firefighters with positive treadmill tests
    Matthew J Budoff
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 W Carson Street, Torrance, CA 90502, USA
    J Cardiovasc Comput Tomogr 3:323-30. 2009
    ....
  32. pmc Cardiovascular events with absent or minimal coronary calcification: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Center, Torrance, CA 90502, USA
    Am Heart J 158:554-61. 2009
    ..In this study, we sought to evaluate the characteristics associated with incident CHD events in the setting of minimal (score <or=10) or absent CAC (score of zero)...
  33. doi request reprint Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA, USA
    Prev Med 49:101-7. 2009
    ..This study was designed to assess whether aged garlic extract therapy with supplements (AGE+S) favorably affects inflammatory and oxidation biomarkers, vascular function and progression of atherosclerosis as compared to placebo...
  34. doi request reprint Reproducibility of coronary artery calcified plaque with cardiac 64-MDCT: the Multi-Ethnic Study of Atherosclerosis
    Matthew Jay Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 W Carson St, RB2, Torrance, CA 90502, USA
    AJR Am J Roentgenol 192:613-7. 2009
    ..The aim of this study was to compare the interscan variability for both Agatston and volume scores derived with newer (16- and 64-MDCT) scanners with that derived with older scanners in the Multi-Ethnic Study of Atherosclerosis...
  35. ncbi request reprint Effects of hormone replacement on progression of coronary calcium as measured by electron beam tomography
    Matthew J Budoff
    Division of Cardiology, Harbor UCLA Research and Education Institute, Torrance, California 90502, USA
    J Womens Health (Larchmt) 14:410-7. 2005
    ..We sought to evaluate the progression of subclinical atherosclerosis in postmenopausal women using no hormone replacement therapy (HRT), combined therapy, and estrogen alone in an observational study...
  36. ncbi request reprint Diabetes and progression of coronary calcium under the influence of statin therapy
    Matthew J Budoff
    Division of Cardiology, Harbor UCLA Medical Center Research and Education Institute, Torrance, Calif 90502, USA
    Am Heart J 149:695-700. 2005
    ..We sought to evaluate the progression of atherosclerosis in asymptomatic persons with type 2 diabetes and measure the influence of statin therapy on CAC progression...
  37. doi request reprint Incidental findings on cardiac computed tomography. Should we look?
    Matthew J Budoff
    Division of Cardiology, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    J Cardiovasc Comput Tomogr 1:97-105. 2007
    ..Until data are available to the opposite, we should use our good judgment and restraint and not perform large-field reconstructions for the explicit purpose of screening...
  38. ncbi request reprint Coronary anomalies by cardiac computed tomographic angiography
    Matthew J Budoff
    Division of Cardiology, Department of Internal Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, California 90502, USA
    Clin Cardiol 29:489-93. 2006
    ..It not only provides high-resolution anatomical information of the coronary artery tree but also helps define other aspects of the cardiovascular anatomy, be it normal or abnormal...
  39. doi request reprint Comparison of coronary artery calcium scores between electron beam computed tomography and 64-multidetector computed tomographic scanner
    Song S Mao
    Division of Cardiology, Los Angeles Biomedical Research Institute and Saint John s Cardiovascular Research Center, Torrance, California, USA
    J Comput Assist Tomogr 33:175-8. 2009
    ..We evaluated the interscan variation in coronary artery calcium (CAC), Agatston score (AS), and volume score (VS) between EBT and 64-MDCT (VCT; GE, Milwaukee, Wis)...
  40. doi request reprint Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium
    Naser Ahmadi
    Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, Torrance, California, USA
    Am J Cardiol 105:459-66. 2010
    ..Increases in OxPL/apoB and lipoprotein(a) correlated strongly with increases in vascular function and predicted a lack of progression of CAC...
  41. ncbi request reprint Association between progression of aortic valve calcification and coronary calcification: assessment by electron beam tomography
    Junichiro Takasu
    Division of Cardiology, Harbor UCLA Research and Education Institute, 1124 W Carson Street, RB2, Torrance, CA 90502
    Acad Radiol 12:298-304. 2005
    ..We sought to examine the relationship of AVC to coronary artery calcification (CC), to assess whether similar risk factors affect the process in a similar way...
  42. ncbi request reprint Coronary calcium scanning
    Ambarish Gopal
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA Research and Education Institute, Torrance, CA 90502, USA
    Am Heart Hosp J 4:43-50. 2006
    ..In summary, coronary calcium detection significantly improves the accuracy of global cardiovascular risk prevention, the noninvasive tracking of the atherosclerotic burden, and the prediction of cardiovascular events...
  43. doi request reprint Mortality incidence and the severity of coronary atherosclerosis assessed by computed tomography angiography
    Matthew P Ostrom
    Division of Cardiology, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California 90502, USA
    J Am Coll Cardiol 52:1335-43. 2008
    ..This study investigated whether cardiac computed tomography angiography (CTA) can predict all-cause mortality in symptomatic patients...
  44. ncbi request reprint Inhibiting progression of coronary calcification using Aged Garlic Extract in patients receiving statin therapy: a preliminary study
    Matthew J Budoff
    Division of Cardiology, Harbor UCLA Medical Center Research and Education Institute, Torrance, CA 90502, USA
    Prev Med 39:985-91. 2004
    ..However, no study has evaluated the ability of AGE to inhibit vascular calcification, a marker of plaque formation in human coronary arteries...
  45. ncbi request reprint Underlying risk factors incrementally add to the standard risk estimate in detecting subclinical atherosclerosis in low- and intermediate-risk middle-aged asymptomatic individuals
    Milind Y Desai
    Ciccarone Preventive Cardiology Center, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Am Heart J 148:871-7. 2004
    ..High burden of coronary artery calcification (CAC) on electron beam tomography (EBT) is a CHD risk equivalent...
  46. ncbi request reprint Ethnic differences of the presence and severity of coronary atherosclerosis
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, 1124 W Carson Street, Bldg RB 2, Torrance, CA, USA
    Atherosclerosis 187:343-50. 2006
    ..The objective of the study is to assess the differences in the prevalence and severity of coronary artery calcification, as a measure of atherosclerosis, in these different ethnic groups...
  47. ncbi request reprint Coronary calcium progression rates with a zero initial score by electron beam tomography
    Ambarish Gopal
    Division of Cardiology, Los Angeles Biomedical Research Center at Harbor UCLA, Torrance, CA, USA
    Int J Cardiol 117:227-31. 2007
    ..In this study, we sought to determine the rate of new calcifications in patients initially presenting with a zero initial score on electron beam tomography (EBT)...
  48. doi request reprint MESA: the NIH-sponsored study that validates atherosclerosis imaging for primary prevention
    Irfan Zeb
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 W Carson Street, Torrance, CA 90502, USA
    Curr Atheroscler Rep 13:353-8. 2011
    ..That is why the US national guidelines have recently elevated their recommendation levels to Class IIa for use of CAC and CIMT in risk stratification of the asymptomatic intermediate-risk population...
  49. doi request reprint Screening for heart disease: C-reactive protein versus coronary artery calcium
    Amish A Patel
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, 1124 W Carson Street, RB2, Torrance, CA 90502, USA
    Expert Rev Cardiovasc Ther 8:125-31. 2010
    ..Current review of the literature available suggests CAC to be more relevant in evaluating CHD in a clinical setting. Given the higher cost of CAC scanning compared with CRP, cost-effectiveness studies are still needed...
  50. doi request reprint Association between coronary artery calcification progression and microalbuminuria: the MESA study
    Andrew P DeFilippis
    Division of Cardiology, The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, Maryland, USA
    JACC Cardiovasc Imaging 3:595-604. 2010
    ..This study sought to evaluate the relationship between microalbuminuria (MA) and the development and progression of atherosclerosis, as assessed by incident and progression of coronary artery calcification (CAC)...
  51. ncbi request reprint Tracking progression of heart disease with cardiac computed tomography
    Matthew J Budoff
    Division of Cardiology, Harbor UCLA Medical Center Research and Education Institute, Torrance, CA 90502, USA
    J Cardiovasc Pharmacol Ther 9:75-82. 2004
    ..An increased rate of progression of coronary calcium seems to indicate a substantially increased risk for adverse cardiac events, suggesting that this modality can be used to monitor the efficacy of therapy...
  52. ncbi request reprint Usefulness of aortic valve calcium scores by electron beam computed tomography as a marker for aortic stenosis
    David M Shavelle
    Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Am J Cardiol 92:349-53. 2003
    ..Results of this study suggest that AVC scores should be calculated routinely for coronary calcium screening EBT scans, and that patients with Agatston AVC scores above a certain level (e.g., >150) should be referred for echocardiography...
  53. ncbi request reprint Continuous probabilistic prediction of angiographically significant coronary artery disease using electron beam tomography
    Matthew J Budoff
    Division of Cardiology, Harbor UCLA Research and Education Institute, Torrance, Calif 90502 2064, USA
    Circulation 105:1791-6. 2002
    ..Such a model could greatly facilitate clinical triage in symptomatic patients with no known CAD...
  54. ncbi request reprint Plasma homocysteine predicts progression of atherosclerosis
    M Leila Rasouli
    Division of Cardiology, Harbor UCLA Medical Center Research and Education Institute, Torrance, CA 90502, USA
    Atherosclerosis 181:159-65. 2005
    ..8 mg/L) had a median yearly progression of 22%, compared to 21% for those with CRP value = 0.9-11 mg/L (p = ns). Presence of elevated HCY (>12 micromol/L) strongly and independently predicts progression of coronary plaque burden...
  55. ncbi request reprint Measures of brachial artery distensibility in relation to coronary calcification
    Matthew J Budoff
    Division of Cardiology, Harbor UCLA Medical Center Research and Education Institute, Torrance, California 90502, USA
    Am J Hypertens 16:350-5. 2003
    ..This study sought to compare measures of brachial artery distensibility to subclinical atherosclerosis as measured by electron beam tomography (EBT)...
  56. ncbi request reprint Electron beam tomography and angiography: sex differences
    Matthew J Budoff
    Division of Cardiology, Saint John s Cardiovascular Research Center, Harbor UCLA Medical Center Research and Education Institute, Torrance, CA 90502, USA
    Am Heart J 143:877-82. 2002
    ....
  57. ncbi request reprint Coronary calcium scanning adds incremental value to patients with positive stress tests
    Daniel H Lamont
    Department of Medicine, Division of Cardiology, Department of Veterans Affairs Medical Center, Long Beach, CA, USA
    Am Heart J 143:861-7. 2002
    ..This study evaluated the negative predictive value and potential clinical utility of EBT to identify patients with a falsely abnormal TMST...
  58. pmc Reduction in downstream test utilization following introduction of coronary computed tomography in a cardiology practice
    Ronald P Karlsberg
    Cardiovascular Research Foundation of Southern California, Beverly Hills, CA, USA
    Int J Cardiovasc Imaging 26:359-66. 2010
    ....
  59. ncbi request reprint Comparison of coronary artery calcium screening image quality between C-150 and e-Speed electron beam scanners
    Matthew J Budoff
    Division of Cardiology, Harbor UCLA Research and Education Institute, 1124 W Carson Street, RB2, Torrance, California 90502, USA
    Acad Radiol 12:309-12. 2005
    ..The aim of this study was to evaluate coronary artery calcium screening image quality between the e-Speed and C-150 scanners (GE Imatron, San Francisco, CA)...
  60. pmc Computed tomography: new horizons
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, California 90502, USA
    Tex Heart Inst J 33:197-200. 2006
  61. doi request reprint Relationship of thoracic aortic calcium to coronary calcium and its progression (from the Multi-Ethnic Study of Atherosclerosis [MESA])
    Juan J Rivera
    Division of Cardiology, Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Hospital, Baltimore, Maryland, USA
    Am J Cardiol 103:1562-7. 2009
    ..25 to 30.18). In conclusion, TAC is associated with the incidence and progression of CAC. The detection of TAC may improve risk stratification efforts. Future clinical outcomes studies are needed to support such an approach...
  62. doi request reprint Cardiac computed tomographic angiography in an outpatient setting: an analysis of clinical outcomes over a 40-month period
    Ambarish Gopal
    Los Angeles Biomedical Research Institute at Harbor UCLA, 1124 W Carson Street, RB2, Torrance, CA 90502, USA
    J Cardiovasc Comput Tomogr 3:90-5. 2009
    ..Cardiac computed tomographic angiography (CTA) provides for accurate noninvasive diagnosis of coronary artery disease (CAD)...
  63. ncbi request reprint Visualizing coronary calcium is associated with improvements in adherence to statin therapy
    Nove K Kalia
    Division of Cardiology, Harbor UCLA Medical Center, Research and Education Institute, Torrance, CA, USA
    Atherosclerosis 185:394-9. 2006
    ..We evaluated whether visualization of coronary calcium would positively affect patients' adherence rates...
  64. ncbi request reprint Prognostic significance of zero coronary calcium scores on cardiac computed tomography
    Shahrzad Shareghi
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 W Carson Street, RB2, Torrance, CA 90502, USA
    J Cardiovasc Comput Tomogr 1:155-9. 2007
    ..Several studies reported event rates of zero for those persons without CAC by cardiac computed tomography (CT)...
  65. ncbi request reprint Noninvasive coronary angiography using computed tomography
    Matthew J Budoff
    Harbor UCLA Medical Center, Division of Cardiology, Torrance, CA 90502 2064, USA
    Expert Rev Cardiovasc Ther 3:123-32. 2005
    ..Compared with magnetic resonance imaging, with a reported accuracy of 72% in the only multicenter study, computed tomography has great promise to become the primary method of noninvasive coronary angiography...
  66. ncbi request reprint Detection of small vessels with electron beam computed tomographic angiography using 1.5 and 3 mm collimator protocols
    Songshou Mao
    Division of Cardiology, Harbor UCLA Research and Education Institute, Torrance, CA 90502, USA
    Int J Cardiovasc Imaging 22:275-82. 2006
    ..To evaluate the effect of scanner collimation on the ability to detect small cardiac vessels using electron beam CT coronary angiography (EBA)...
  67. ncbi request reprint Aortic atherosclerosis detected with electron-beam CT as a predictor of obstructive coronary artery disease
    Junichiro Takasu
    Division of Cardiology, Harbor UCLA Medical Center, Research and Education Institute, 1124 W Carson St, Bldg RB 2, Torrance, CA 90502 2064, USA
    Acad Radiol 10:631-7. 2003
    ..The aim of this study was to evaluate the usefulness of measurement of aortic atherosclerosis with electron-beam CT as an independent predictor of obstructive coronary artery disease (CAD)...
  68. ncbi request reprint Ability of calibration phantom to reduce the interscan variability in electron beam computed tomography
    Matthew J Budoff
    Department of Medicine, Division of Cardiology, Harbor UCLA Research and Education Institute, 1124 W Carson Street RB 2, Torrance, CA 90502, USA
    J Comput Assist Tomogr 26:886-91. 2002
    ..To test the hypothesis that a calibration phantom would improve interpatient and interscan variability in coronary artery calcium (CAC) studies...
  69. ncbi request reprint Reproducibility of three different scoring systems for measurement of coronary calcium
    Hideya Yamamoto
    Saint John s Cardiovacular Research Center, Harbor UCLA Research and Education Institute, Torrance, CA, USA
    Int J Cardiovasc Imaging 18:391-7. 2002
    ..We sought to assess the reproducibility of two new software systems, InSight and AccuImage, and the console workstation of an EBT scanner for measuring coronary calcification...
  70. ncbi request reprint Coronary calcium scanning in geriatric cardiology
    Ambarish Gopal
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    Am J Geriatr Cardiol 16:369-75. 2007
    ..This article will review such a screening method, namely coronary calcium scanning, in the field of geriatric cardiology...
  71. ncbi request reprint Assessment of coronary plaque morphology by contrast-enhanced computed tomographic angiography: comparison with intravascular ultrasound
    Margaret Leila Rasouli
    Division of Cardiology, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California, USA
    Coron Artery Dis 17:359-64. 2006
    ..Computed tomographic (CT) angiography provides accurate noninvasive assessment for coronary artery stenosis. The ability of CT angiography to determine plaque morphology remains unclear...
  72. pmc Relationships of thoracic aortic wall calcification to cardiovascular risk factors: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Junichiro Takasu
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    Am Heart J 155:765-71. 2008
    ..We performed a cross-sectional study to determine which of these variables are independently associated with thoracic calcium...
  73. doi request reprint Comparison of methods to measure heart size using noncontrast-enhanced computed tomography: correlation with left ventricular mass
    Kurt R Daniel
    Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Comput Assist Tomogr 32:934-41. 2008
    ..Left ventricular (LV) mass is a useful independent predictor of cardiovascular events. We sought to develop a new correlate of LV mass using noncontrast-enhanced cardiac computed tomography (NCE-CCT)...
  74. ncbi request reprint Electron beam CT versus helical CT scans for assessing coronary calcification: current utility and future directions
    Khurram Nasir
    Division of Cardiology, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Am Heart J 146:969-77. 2003
    ..Traditional risk factors for coronary artery disease predict the development of atherosclerosis; however, their ability to identify individual patients at risk of events is limited...
  75. ncbi request reprint Framingham risk equation underestimates subclinical atherosclerosis risk in asymptomatic women
    Erin D Michos
    Ciccarone Preventive Cardiology Center, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Atherosclerosis 184:201-6. 2006
    ..However, the adequacy of FRE for identifying asymptomatic women with CAC is unknown...
  76. doi request reprint Relationship of aortic valve calcification with coronary artery calcium severity: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Khurram Nasir
    Division of Cardiology, Blalock 524 C, Johns Hopkins University, 600N Wolfe Street, Baltimore, MD 21287, USA
    J Cardiovasc Comput Tomogr 4:41-6. 2010
    ..Aortic valve calcification (AVC) and atherosclerosis share causative and pathologic features...
  77. ncbi request reprint Comparison of three generations of electron beam tomography on image noise and reproducibility, a phantom study
    Alex Chau
    Department of Medicine, Division of Cardiology, Harbor UCLA Research and Education Institute, Torrance, CA 90502, USA
    Invest Radiol 41:522-6. 2006
    ..We sought to evaluate the image quality of each machine to examine whether patients scanned on a previous model would have similar image quality and results to those scanned on the newest scanner...
  78. doi request reprint Association of plaque in the carotid and coronary arteries, using MDCT angiography
    Yasmin S Hamirani
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Department of Cardiovascular Computed Tomography, 1124 W, Carson Street, Torrance, CA 90502, United States
    Atherosclerosis 211:141-5. 2010
    ..We evaluated MDCT correlation of total plaque and various plaque subtypes in carotid and coronary arteries...
  79. pmc Impaired aortic distensibility measured by computed tomography is associated with the severity of coronary artery disease
    Naser Ahmadi
    Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, 1124 W Carson Street, RB2, Torrance, CA 90502, USA
    Int J Cardiovasc Imaging 27:459-69. 2011
    ..05). Impaired aortic distensibility strongly correlates with the severity of coronary atherosclerosis. Addition of ADI to CAC and traditional risk factors provides incremental value to predict at-risk individuals...
  80. doi request reprint Noninvasive anatomical coronary artery imaging versus myocardial perfusion imaging: which confers superior diagnostic and prognostic information?
    Yalcin Hacioglu
    Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
    J Comput Assist Tomogr 34:637-44. 2010
    ..Further studies comparing the short- and long-term clinical outcomes and cost-effectiveness of these tests are required to determine their optimal role in the management of symptomatic patients with suspected CAD...
  81. doi request reprint The diagnostic accuracy of 64-detector cardiac computed tomography compared with stress nuclear imaging in patients undergoing invasive cardiac catheterization
    Yasmin S Hamirani
    Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA, USA
    J Comput Assist Tomogr 34:645-51. 2010
    ..The aim of this study was to evaluate the diagnostic accuracy of nuclear stress imaging as compared with noninvasive coronary artery imaging using 64-detector row cardiac computed tomography...
  82. doi request reprint Diagnostic accuracy of coronary computed tomography angiography as interpreted on a mobile handheld phone device
    Troy M LaBounty
    Department of Medicine, Weill Cornell Medical College New York Presbyterian Hospital, New York, New York 10021, USA
    JACC Cardiovasc Imaging 3:482-90. 2010
    ....
  83. ncbi request reprint Thebesian valve imaging with electron beam CT angiography: implications for resynchronization therapy
    Jerold S Shinbane
    Division of Cardiology, Harbor UCLA Research and Education Institute, Torrance, California 90502 2064, USA
    Pacing Clin Electrophysiol 27:1566-7. 2004
    ..Electron beam computed tomographic angiography can provide detailed information for coronary sinus instrumentation, including anomalies potentially affecting the approach to resynchronization therapy...
  84. ncbi request reprint Methodology for improved detection of coronary stenoses with computed tomographic angiography
    Matthew J Budoff
    Department of Medicine, Division of Cardiology, Harbor UCLA Medical Center and Saint John s Cardiovascular Research Center, Torrance 90502, USA
    Am Heart J 148:1085-90. 2004
    ..We assessed the accuracy of electron beam computed tomographic angiography (EBA) for detection of coronary stenoses, using improved triggering techniques and thinner slice collimation...
  85. ncbi request reprint Comparison of prevalence and severity of coronary calcium determined by electron beam tomography among various ethnic groups
    Arun Hatwalkar
    Division of Cardiology, Department of Medicine, Harbor UCLA Medical Center, Torrance 90502 2064, USA
    Am J Cardiol 91:1225-7. 2003

Research Grants6

  1. Ventricular Size and Valve Calcification Measures by CT
    Matthew J Budoff; Fiscal Year: 2010
    ..abstract_text> ..
  2. Ventricular Size and Value Calcification Measures by CT
    Matthew Budoff; Fiscal Year: 2006
    ..abstract_text> ..
  3. Ventricular Size and Valve Calcification Measures by CT
    Matthew Budoff; Fiscal Year: 2009
    ..abstract_text> ..