Research Topics
| Xudong YuanSummaryAffiliation: Long Island University Country: USA Publications
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Detail Information
Publications
The development and mechanism studies of cationic chitosan-modified biodegradable PLGA nanoparticles for efficient siRNA drug deliveryXudong Yuan
Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy, Long Island University, 75 DeKalb Avenue, Brooklyn, New York 11201 5497, USA
Pharm Res 27:1285-95. 2010....
The analysis of heavy metals in Chinese herbal medicine by flow injection-mercury hydride system and graphite furnace atomic absorption spectrometryXudong Yuan
Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA
Phytochem Anal 20:293-7. 2009..Simple and robust atomic absorption spectrometry (AAS) analytical methods were developed to determine the contents of arsenic (As), lead (Pb) and mercury (Hg) contained in Chinese herbal medicine products or Chinese proprietary medicine...
Analytical methods for heavy metals in herbal medicinesXudong Yuan
Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA
Phytochem Anal 22:189-98. 2011..In this review, different analytical methods for analysis of heavy metals in herbal medicines are discussed...
Recent advances of siRNA delivery by nanoparticlesXudong Yuan
Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201 5497, USA
Expert Opin Drug Deliv 8:521-36. 2011..Pharmacology and pharmacokinetic studies also present another great challenge for nanoparticle delivery systems, owing to the unique nature of siRNA oligonucleotides compared with small molecules...
The preformulation stability studies of a proline prodrug of methotrexateAnn Stephenson
Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York 11201, USA
Med Chem 8:622-8. 2012..It was also found that the prodrug is stable in the HPLC diluent, consisting of water and acetonitrile; stored bench-top and protected from light for up to two weeks...
SiRNA drug delivery by biodegradable polymeric nanoparticlesXudong Yuan
Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, 75 DeKalb Avenue, NY 11201, USA
J Nanosci Nanotechnol 6:2821-8. 2006....
Development of methotrexate proline prodrug to overcome resistance by MDA-MB-231 cellsZhiqian Wu
Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA
Bioorg Med Chem Lett 20:5108-12. 2010..But for methotrexate resistant MDA-MB-231 cells, Pro-MTX showed stronger activity than methotrexate. The results indicated that the proline prodrug of methotrexate may overcome the resistance of human breast cancer cells in culture...
Physicochemical studies of binary eutectic of ibuprofen and ketoprofen for enhanced transdermal drug deliveryXudong Yuan
Department of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY, USA
Drug Dev Ind Pharm 36:1168-76. 2010..The thermodynamic, eutectic, and crystalline properties of ibuprofen and ketoprofen binary mixtures were investigated using differential scanning calorimetry (DSC) and X-ray powder diffractometry (XRPD)...
Development of acetaminophen proline prodrugZhiqian Wu
Long Island University, Brooklyn, NY 11201, United States
Bioorg Med Chem Lett 20:3851-4. 2010..Physicochemical characteristics such as melting point and stability of newly synthesized prodrug were determined by MDSC technique...
