Gwenn S Smith

Summary

Affiliation: Long Island Jewish Medical Center
Country: USA

Publications

  1. pmc Serotonin modulation of cerebral glucose metabolism in depressed older adults
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, New York, USA
    Biol Psychiatry 66:259-66. 2009
  2. ncbi request reprint Serotonin modulation of cerebral glucose metabolism measured with positron emission tomography (PET) in human subjects
    Gwenn S Smith
    Department of Psychiatry Research, Hillside Hospital, Neuroscience Institute of the North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Synapse 45:105-12. 2002
  3. ncbi request reprint Effects of serotonin transporter promoter polymorphisms on serotonin function
    Gwenn S Smith
    Department of Psychiatry, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 29:2226-34. 2004
  4. ncbi request reprint Applications of neuroreceptor imaging to psychiatry research
    Gwenn S Smith
    Department of Psychiatry Research, Zucker Hillside Hospital of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Psychopharmacol Bull 37:26-65. 2003
  5. ncbi request reprint Acute and chronic effects of citalopram on cerebral glucose metabolism in geriatric depression
    Gwenn S Smith
    Department of Psychiatry Research, Hillside Hospital and the Neuroscience Institute of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Am J Geriatr Psychiatry 10:715-23. 2002
  6. ncbi request reprint Glucose metabolic response to total sleep deprivation, recovery sleep, and acute antidepressant treatment as functional neuroanatomic correlates of treatment outcome in geriatric depression
    Gwenn S Smith
    Department of Psychiatry Research, Hillside Hospital of the North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Am J Geriatr Psychiatry 10:561-7. 2002
  7. ncbi request reprint Serotonin modulation of cerebral glucose metabolism in normal aging
    Sara Goldberg
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Neurobiol Aging 25:167-74. 2004
  8. pmc Cholinergic modulation of the cerebral metabolic response to citalopram in Alzheimer's disease
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Brain 132:392-401. 2009
  9. pmc Cerebral glucose metabolic response to combined total sleep deprivation and antidepressant treatment in geriatric depression: a randomized, placebo-controlled study
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Psychiatry Res 171:1-9. 2009
  10. doi request reprint Selective serotonin reuptake inhibitor (SSRI) modulation of striatal dopamine measured with [11C]-raclopride and positron emission tomography
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Synapse 63:1-6. 2009

Detail Information

Publications23

  1. pmc Serotonin modulation of cerebral glucose metabolism in depressed older adults
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, New York, USA
    Biol Psychiatry 66:259-66. 2009
    ..The hypothesis was tested that smaller decreases in metabolism would be observed in cortical and limbic regions in depressed older adults relative to control subjects...
  2. ncbi request reprint Serotonin modulation of cerebral glucose metabolism measured with positron emission tomography (PET) in human subjects
    Gwenn S Smith
    Department of Psychiatry Research, Hillside Hospital, Neuroscience Institute of the North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Synapse 45:105-12. 2002
    ..Future studies will evaluate how the acute metabolic response to citalopram relates to the metabolic response after chronic treatment in patients with geriatric depression...
  3. ncbi request reprint Effects of serotonin transporter promoter polymorphisms on serotonin function
    Gwenn S Smith
    Department of Psychiatry, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 29:2226-34. 2004
    ....
  4. ncbi request reprint Applications of neuroreceptor imaging to psychiatry research
    Gwenn S Smith
    Department of Psychiatry Research, Zucker Hillside Hospital of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Psychopharmacol Bull 37:26-65. 2003
    ..These data will provide important insights into the neurochemical substrates of treatment response variability in psychiatric disorders that will have important implications for the refinement of pharmacotherapy...
  5. ncbi request reprint Acute and chronic effects of citalopram on cerebral glucose metabolism in geriatric depression
    Gwenn S Smith
    Department of Psychiatry Research, Hillside Hospital and the Neuroscience Institute of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Am J Geriatr Psychiatry 10:715-23. 2002
    ....
  6. ncbi request reprint Glucose metabolic response to total sleep deprivation, recovery sleep, and acute antidepressant treatment as functional neuroanatomic correlates of treatment outcome in geriatric depression
    Gwenn S Smith
    Department of Psychiatry Research, Hillside Hospital of the North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Am J Geriatr Psychiatry 10:561-7. 2002
    ....
  7. ncbi request reprint Serotonin modulation of cerebral glucose metabolism in normal aging
    Sara Goldberg
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Neurobiol Aging 25:167-74. 2004
    ..These results suggest different compensatory processes in anterior compared to posterior brain regions secondary to the age-related loss of serotonin innervation...
  8. pmc Cholinergic modulation of the cerebral metabolic response to citalopram in Alzheimer's disease
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Brain 132:392-401. 2009
    ..The combined cerebral metabolic effects of galantamine and citalopram suggest, consistent with preclinical data, a synergistic interaction of cholinergic and serotonergic systems...
  9. pmc Cerebral glucose metabolic response to combined total sleep deprivation and antidepressant treatment in geriatric depression: a randomized, placebo-controlled study
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Psychiatry Res 171:1-9. 2009
    ....
  10. doi request reprint Selective serotonin reuptake inhibitor (SSRI) modulation of striatal dopamine measured with [11C]-raclopride and positron emission tomography
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Synapse 63:1-6. 2009
    ....
  11. pmc The functional neuroanatomy of geriatric depression
    Gwenn S Smith
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, New York, USA
    Int J Geriatr Psychiatry 24:798-808. 2009
    ....
  12. ncbi request reprint Neuroendocrine response to intravenous citalopram in healthy control subjects: pharmacokinetic influences
    Francis E Lotrich
    Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
    Psychopharmacology (Berl) 178:268-75. 2005
    ..The neuroendocrine response to intravenous citalopram may provide an acute, functional, in vivo measure of the neural serotonin (5-HT) system...
  13. doi request reprint Cerebral glucose metabolism and D2/D3 receptor availability in young adults with cannabis dependence measured with positron emission tomography
    Serge Sevy
    The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, NY 11004, USA
    Psychopharmacology (Berl) 197:549-56. 2008
    ....
  14. pmc Diffusion tensor imaging of neuropsychiatric symptoms in mild cognitive impairment and Alzheimer's dementia
    Sarah K Tighe
    Johns Hopkins University School of Medicine, Department of Psychiatry, Baltimore, MD, USA
    J Neuropsychiatry Clin Neurosci 24:484-8. 2012
    ..Further imaging studies are necessary to elucidate the role of the AC in the pathophysiology of neuropsychiatric symptoms in AD and MCI...
  15. ncbi request reprint Evidence for a role of the arachidonic acid cascade in affective disorders: a review
    M Elizabeth Sublette
    Psychiatry Department, The Zucker Hillside Hospital North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Bipolar Disord 6:95-105. 2004
    ..Possible links between this and other prevailing hypotheses are considered, and implications for further research and for treatment are discussed...
  16. ncbi request reprint Relevance of assessing drug concentration exposure in pharmacogenetic and imaging studies
    Francis E Lotrich
    Department of Psychiatry, Western Psychiatric Institute and Clinics, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Psychopharmacol 20:33-40. 2006
    ..For the design and interpretation of neuroimaging, pharmacogenetic, and behavioural studies, the assessment of drug concentration exposure is therefore feasible and has potentially important ramifications...
  17. pmc Functional neuroimaging in geriatric depression
    Faith M Gunning
    Department of Psychiatry, Institute of Geriatric Psychiatry, Weill Cornell Medical College, 21 Bloomingdale Road, White Plains, NY 10605, USA
    Psychiatr Clin North Am 34:403-22, viii. 2011
    ..Furthermore, geriatric depression provides a logical context within which to study the role of specific functional abnormalities in both antidepressant response and key behavioral and cognitive abnormalities of mood disorders...
  18. doi request reprint Diffusion tensor imaging atlas-based analyses in major depression after mild traumatic brain injury
    Vani Rao
    Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD, USA
    J Neuropsychiatry Clin Neurosci 24:309-15. 2012
    ..These preliminary results highlight the need for additional studies, including studies using a larger sample and appropriate controls...
  19. ncbi request reprint Accelerating symptom-reduction in late-life depression: a double-blind, randomized, placebo-controlled trial of sleep deprivation
    Charles F Reynolds
    Intervention Research Center for Late Life Mood Disorders IRC LLMD, Univ of Pittsburgh School of Medicine, 3811 O Hara Street, E 113521, Pittsburgh, PA 15213, USA
    Am J Geriatr Psychiatry 13:353-8. 2005
    ..Authors tested the hypothesis that one night of total sleep deprivation (TSD) would accelerate antidepressant response to paroxetine, as compared with TSD+placebo (PBO) and paroxetine-alone, in late-life major depression...
  20. ncbi request reprint Microstructural white matter changes in carriers of the DYT1 gene mutation
    Maren Carbon
    Center for Neurosciences, North Shore Long Island Jewish Research Institute, Manhasset, NY 11030, USA
    Ann Neurol 56:283-6. 2004
    ..Abnormal anatomical connectivity of the supplementary motor area may contribute to the susceptibility of DYT1 carriers to develop clinical manifestations of dystonia...
  21. ncbi request reprint Neuroimaging in geriatric psychiatry
    Gwenn S Smith
    Am J Geriatr Psychiatry 12:551-3. 2004
  22. ncbi request reprint Structural neuroimaging in geriatric psychiatry
    Gwenn S Smith
    Am J Geriatr Psychiatry 14:809-11. 2006
  23. ncbi request reprint Translational research in late-life mood disorders: implications for future intervention and prevention research
    Gwenn S Smith
    PET Centre, Centre for Addiction and Mental Health, Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Neuropsychopharmacology 32:1857-75. 2007
    ..Geriatric depression could serve as a model for translational research integrating basic and clinical neuroscience approaches that would have implications for the study of other neuropsychiatric disorders...