Research Topics
Genomes and GenesSpecies | S SevySummaryAffiliation: Long Island Jewish Medical Center Country: USA Publications
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Publications
Olanzapine vs. risperidone in patients with first-episode schizophrenia and a lifetime history of cannabis use disorders: 16-week clinical and substance use outcomesSerge Sevy
The Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, NY 11030, USA
Psychiatry Res 188:310-4. 2011..If clinicians are choosing between olanzapine versus risperidone treatment for this population, their decision should be based upon factors other than symptom response and short-term substance misuse...
Contingency valuation and preferences of health states associated with side effects of antipsychotic medications in schizophreniaS Sevy
Department of Psychiatry, Mt Sinai School of Medicine, New York, NY, USA
Schizophr Bull 27:643-51. 2001..Our results suggest that WTP has some construct validity in valuating and measuring preferences of health states associated with side effects of antipsychotics in schizophrenia...
Are cannabis use disorders associated with an earlier age at onset of psychosis? A study in first episode schizophreniaSerge Sevy
The Zucker Hillside Hospital of the North Shore Long Island Jewish Health System, Psychiatry Research, Glen Oaks, NY 11004, USA
Schizophr Res 120:101-7. 2010..The purpose of this study is to determine if an earlier age at onset of positive symptoms in schizophrenia is associated with cannabis use disorders (CUD)...
Cerebral glucose metabolism and D2/D3 receptor availability in young adults with cannabis dependence measured with positron emission tomographySerge Sevy
The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, NY 11004, USA
Psychopharmacology (Berl) 197:549-56. 2008....
Relationship between costs and symptoms in schizophrenia patients treated with antipsychotic medication: a reviewSerge Sevy
Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
J Clin Psychiatry 65:756-65. 2004..The purpose of this review is to understand how changes in costs of illness are related to the effects of antipsychotic medications on symptoms in schizophrenia patients...
Iowa gambling task in schizophrenia: a review and new data in patients with schizophrenia and co-occurring cannabis use disordersSerge Sevy
Department of Psychiatry Research, Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY, 11004, USA
Schizophr Res 92:74-84. 2007..To test this hypothesis, we compared schizophrenia patients with (SCZ((+))) or without (SCZ((-))) cannabis use disorders, to healthy subjects, on measures of cognition and IGT performance...
Emotion-based decision-making in healthy subjects: short-term effects of reducing dopamine levelsSerge Sevy
Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Yeshiva University, Bronx, and Psychiatry Research Department, The Zucker Hillside Hospital, Glen Oaks, NY, USA
Psychopharmacology (Berl) 188:228-35. 2006..So far, it is unclear what aspects of addictive behaviors are related to a dopaminergic dysfunction...
Double-blind, placebo-controlled study of modafinil for fatigue and cognition in schizophrenia patients treated with psychotropic medicationsSerge Sevy
The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
J Clin Psychiatry 66:839-43. 2005..To assess the effects of modafinil on fatigue, symptoms, attention, working memory, and executive functioning in schizophrenia patients treated with psychotropic medications...
Correlates of substance misuse in patients with first-episode schizophrenia and schizoaffective disorderS Sevy
Long Island Jewish Medical Center, Hillside Division, Leon Lowenstein Research Building, 266th Street @ 7th Avenue, Glen Oaks, NY 11004, USA
Acta Psychiatr Scand 104:367-74. 2001..CONCLUSION: First-episode patients with a history of substance misuse have higher intellectual functioning, which may be associated with higher premorbid socioeconomic status and cognitive functioning...
Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formationP R Szeszko
Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
Mol Psychiatry 10:631-6. 2005..These findings implicate genetic involvement of BDNF in variation of human hippocampal volume and suggest that this effect may be greater among patients compared to healthy volunteers...
Cortical thinning in cingulate and occipital cortices in first episode schizophreniaKatherine L Narr
Laboratory of Neuro Imaging, Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California, USA
Biol Psychiatry 58:32-40. 2005....
The relationship between insight and symptoms in schizophreniaSerge Sevy
Department of Psychiatry, Mt. Sinai School of Medicine, New York, NY, USA
Compr Psychiatry 45:16-9. 2004..Treatment studies that measure insight could answer the question of whether these deficits in awareness improve along with positive and cognitive symptoms...
Patterns of stress in schizophreniaJulia D Betensky
Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
Psychiatry Res 160:38-46. 2008....
Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophreniaPhilip R Szeszko
Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
Neuropsychopharmacology 33:976-84. 2008..These abnormalities have clinical and neuropsychological correlates, which may be useful in further characterizing structure-function relations in schizophrenia and constraining neurobiological models of the disorder...
CSF sub-compartments in relation to plasma osmolality in healthy controls and in patients with first episode schizophreniaHandan Gunduz-Bruce
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
Psychiatry Res 155:57-66. 2007..These results suggest that plasma osmolality is related to ventricle size in healthy volunteers and that this physiological link is impaired in patients with first episode schizophrenia...
DRD2 promoter region variation as a predictor of sustained response to antipsychotic medication in first-episode schizophrenia patientsTodd Lencz
Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
Am J Psychiatry 163:529-31. 2006....
Anterior cingulate grey-matter deficits and cannabis use in first-episode schizophreniaPhilip R Szeszko
Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd Street, Glen Oaks, NY 11004, USA
Br J Psychiatry 190:230-6. 2007..Despite the high prevalence of cannabis use in schizophrenia, few studies have examined the potential relationship between cannabis exposure and brain structural abnormalities in schizophrenia...
White matter abnormalities in first-episode schizophrenia or schizoaffective disorder: a diffusion tensor imaging studyPhilip R Szeszko
The Zucker Hillside Hospital, Department of Psychiatry Research, 75 59 263rd St, Glen Oaks, NY 11004, USA
Am J Psychiatry 162:602-5. 2005..The goal of this study was to investigate brain white matter abnormalities by using diffusion tensor imaging in patients with schizophrenia or schizoaffective disorder close to illness onset...
Decision-making impairments in adolescents with early-onset schizophreniaHana M Kester
Department of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
Schizophr Res 85:113-23. 2006..These findings have potential implications for understanding the increased vulnerability for the development of substance abuse in adolescents with schizophrenia...
The Insight-Adherence-Abstinence triad: an integrated treatment focus for cannabis-using first-episode schizophrenia patientsRachel Miller
Research Department, The Zucker Hillside Hospital NSLIJ, Glen Oaks, New York 11004, USA
Bull Menninger Clin 69:220-36. 2005..Interventions recognize the many needs of cannabis-using first-episode patients and therefore include supportive, cognitive-behavioral, behavioral, and motivational therapies, as well as skill building and psychoeducation...
Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizotypal personality disorderVivian Mitropoulou
Department of Psychiatry, Mt Sinai School of Medicine Clinical Reseach Center, New York, NY 10029, USA
Schizophr Res 70:27-31. 2004..We hypothesized that SPD patients would demonstrate comparable or lower DA and HPA responses after 2-DG to HV...
Mapping cortical thickness and gray matter concentration in first episode schizophreniaKatherine L Narr
Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1769, USA
Cereb Cortex 15:708-19. 2005..Cortical thickness and gray matter concentration mapping produce similar results, although the concentration metric may be influenced by diagnostic differences in extra-cortical cerebrospinal fluid and surface curvature/complexity...
Research Grants
- Addiction and Subsequent Schizophrenia: A Link?Serge Sevy; Fiscal Year: 2007..abstract_text> ..
