Sidhartha Ray

Summary

Affiliation: Long Island University
Country: USA

Publications

  1. ncbi request reprint Differential effects of IH636 grape seed proanthocyanidin extract and a DNA repair modulator 4-aminobenzamide on liver microsomal cytochrome 4502E1-dependent aniline hydroxylation
    S D Ray
    Department of Pharmacology, Toxicology and Medicinal Chemistry, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York 11201, USA
    Mol Cell Biochem 218:27-33. 2001
  2. ncbi request reprint Oxidative stress is the master operator of drug and chemically-induced programmed and unprogrammed cell death: Implications of natural antioxidants in vivo
    S D Ray
    Molecular Toxicology Program, Department of Pharmacology, Toxicology and Medicinal Chemistry, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA
    Biofactors 21:223-32. 2004
  3. ncbi request reprint Short-term and long-term in vivo exposure to an ephedra- and caffeine-containing metabolic nutrition system does not induce cardiotoxicity in B6C3F1 mice
    Sidhartha Ray
    Molecular Toxicology Program, Division of Pharmacology, Toxicology and Medicinal Chemistry, Arnold and Marie Schawrtz College of Pharmacy and Health Sciences, Long Island University, 1 University Plaza, Brooklyn, NY 11201, USA
    Arch Toxicol 79:330-40. 2005
  4. pmc A novel dietary supplement containing multiple phytochemicals and vitamins elevates hepatorenal and cardiac antioxidant enzymes in the absence of significant serum chemistry and genomic changes
    Elida Bulku
    Molecular Toxicology Laboratories, Division of Pharmaceutical Sciences, A and M Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY, USA
    Oxid Med Cell Longev 3:129-44. 2010
  5. doi request reprint Long term exposure effect of a unique metabolic nutrition system containing a diverse group of phytochemicals on serum chemistry and genomic and non-genomic changes in the liver of female B6C3F1 mice
    Sidhartha D Ray
    Molecular Toxicology Laboratories, Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York 11201, USA
    Phytother Res 22:458-71. 2008
  6. ncbi request reprint Synergy of Pancratistatin and Tamoxifen in inducing apoptosis in breast cancer cells
    Sidhartha Ray
    Division ofPharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 1120, USA
    Cancer Biol Ther 7:385-6. 2008
  7. ncbi request reprint Pre-exposure to a novel nutritional mixture containing a series of phytochemicals prevents acetaminophen-induced programmed and unprogrammed cell deaths by enhancing BCL-XL expression and minimizing oxidative stress in the liver
    Sidhartha D Ray
    Molecular Toxicology Laboratories, Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA
    Mol Cell Biochem 293:119-36. 2006
  8. ncbi request reprint Proanthocyanidin exposure to B6C3F1 mice significantly attenuates dimethylnitrosamine-induced liver tumor induction and mortality by differentially modulating programmed and unprogrammed cell deaths
    Sidhartha D Ray
    Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA
    Mutat Res 579:81-106. 2005
  9. ncbi request reprint Ca(2+)-calmodulin antagonist chlorpromazine and poly(ADP-ribose) polymerase modulators 4-aminobenzamide and nicotinamide influence hepatic expression of BCL-XL and P53 and protect against acetaminophen-induced programmed and unprogrammed cell death in mic
    S D Ray
    Molecular Toxicology Program, Department of Pharmacology, Toxicology and Medicinal Chemistry, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA
    Free Radic Biol Med 31:277-91. 2001
  10. ncbi request reprint In vivo protection of dna damage associated apoptotic and necrotic cell deaths during acetaminophen-induced nephrotoxicity, amiodarone-induced lung toxicity and doxorubicin-induced cardiotoxicity by a novel IH636 grape seed proanthocyanidin extract
    S D Ray
    Division of Pharmacology, Toxicology and Medicinal Chemistry, Arnold and Marie Schwartz College of Pharmacy and Health Sciences Long Island University, Brooklyn, NY 11201, USA
    Res Commun Mol Pathol Pharmacol 107:137-66. 2000

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Differential effects of IH636 grape seed proanthocyanidin extract and a DNA repair modulator 4-aminobenzamide on liver microsomal cytochrome 4502E1-dependent aniline hydroxylation
    S D Ray
    Department of Pharmacology, Toxicology and Medicinal Chemistry, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York 11201, USA
    Mol Cell Biochem 218:27-33. 2001
    ..Collectively, these results may suggest that GSPE has the ability to inhibit CYP-4502E1, and this is an additional cytoprotective attribute, in conjunction with its novel antioxidant and/or antiendonucleolytic potential...
  2. ncbi request reprint Oxidative stress is the master operator of drug and chemically-induced programmed and unprogrammed cell death: Implications of natural antioxidants in vivo
    S D Ray
    Molecular Toxicology Program, Department of Pharmacology, Toxicology and Medicinal Chemistry, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA
    Biofactors 21:223-32. 2004
    ....
  3. ncbi request reprint Short-term and long-term in vivo exposure to an ephedra- and caffeine-containing metabolic nutrition system does not induce cardiotoxicity in B6C3F1 mice
    Sidhartha Ray
    Molecular Toxicology Program, Division of Pharmacology, Toxicology and Medicinal Chemistry, Arnold and Marie Schawrtz College of Pharmacy and Health Sciences, Long Island University, 1 University Plaza, Brooklyn, NY 11201, USA
    Arch Toxicol 79:330-40. 2005
    ....
  4. pmc A novel dietary supplement containing multiple phytochemicals and vitamins elevates hepatorenal and cardiac antioxidant enzymes in the absence of significant serum chemistry and genomic changes
    Elida Bulku
    Molecular Toxicology Laboratories, Division of Pharmaceutical Sciences, A and M Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY, USA
    Oxid Med Cell Longev 3:129-44. 2010
    ..Additionally, this study reiterates the potential benefits of exposure to a pharmacologically relevant combination of phytochemicals compared to a single phytochemical entity...
  5. doi request reprint Long term exposure effect of a unique metabolic nutrition system containing a diverse group of phytochemicals on serum chemistry and genomic and non-genomic changes in the liver of female B6C3F1 mice
    Sidhartha D Ray
    Molecular Toxicology Laboratories, Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York 11201, USA
    Phytother Res 22:458-71. 2008
    ..This study indicates that a caffeine and ephedra containing metabolic nutrition system is non-toxic and non-hepatotoxic in mice at up to 10x the human consumption dose of ephedra...
  6. ncbi request reprint Synergy of Pancratistatin and Tamoxifen in inducing apoptosis in breast cancer cells
    Sidhartha Ray
    Division ofPharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 1120, USA
    Cancer Biol Ther 7:385-6. 2008
  7. ncbi request reprint Pre-exposure to a novel nutritional mixture containing a series of phytochemicals prevents acetaminophen-induced programmed and unprogrammed cell deaths by enhancing BCL-XL expression and minimizing oxidative stress in the liver
    Sidhartha D Ray
    Molecular Toxicology Laboratories, Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA
    Mol Cell Biochem 293:119-36. 2006
    ....
  8. ncbi request reprint Proanthocyanidin exposure to B6C3F1 mice significantly attenuates dimethylnitrosamine-induced liver tumor induction and mortality by differentially modulating programmed and unprogrammed cell deaths
    Sidhartha D Ray
    Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA
    Mutat Res 579:81-106. 2005
    ....
  9. ncbi request reprint Ca(2+)-calmodulin antagonist chlorpromazine and poly(ADP-ribose) polymerase modulators 4-aminobenzamide and nicotinamide influence hepatic expression of BCL-XL and P53 and protect against acetaminophen-induced programmed and unprogrammed cell death in mic
    S D Ray
    Molecular Toxicology Program, Department of Pharmacology, Toxicology and Medicinal Chemistry, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA
    Free Radic Biol Med 31:277-91. 2001
    ....
  10. ncbi request reprint In vivo protection of dna damage associated apoptotic and necrotic cell deaths during acetaminophen-induced nephrotoxicity, amiodarone-induced lung toxicity and doxorubicin-induced cardiotoxicity by a novel IH636 grape seed proanthocyanidin extract
    S D Ray
    Division of Pharmacology, Toxicology and Medicinal Chemistry, Arnold and Marie Schwartz College of Pharmacy and Health Sciences Long Island University, Brooklyn, NY 11201, USA
    Res Commun Mol Pathol Pharmacol 107:137-66. 2000
    ..Taken together, these events undoubtedly establish GSPE's abundant bioavailability, and the power to defend multiple target organs from toxic assaults induced by structurally diverse and functionally different entities in vivo...
  11. ncbi request reprint Unique organoprotective properties of a novel IH636 grape seed proanthocyanidin extract on cadmium chloride-induced nephrotoxicity, dimethylnitrosamine (DMN)-induced splenotoxicity and mocap-induced neurotoxicity in mice
    S D Ray
    Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA
    Res Commun Mol Pathol Pharmacol 107:105-28. 2000
    ..Taken together, this study suggests that in vivo GSPE-preexposure may protect multiple target organs from a variety of toxic assaults induced by diverse chemical entities...
  12. ncbi request reprint Diclofenac induced in vivo nephrotoxicity may involve oxidative stress-mediated massive genomic DNA fragmentation and apoptotic cell death
    E J Hickey
    Molecular Toxicology Program, Division of Pharmacology, Toxicology and Medicinal Chemistry, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA
    Free Radic Biol Med 31:139-52. 2001
    ....
  13. ncbi request reprint Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract
    Debasis Bagchi
    Department of Pharmacy Sciences, Medical Center, School of Pharmacy and Creighton University Health Professions, 2500 California Plaza, Omaha, NE 68178, USA
    Mutat Res 523:87-97. 2003
    ..These results demonstrate that GSPE may serve as a potential therapeutic tool in promoting cardiovascular health via a number of novel mechanisms...
  14. ncbi request reprint Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract
    Debasis Bagchi
    Creighton University School of Pharmacy and Allied Health Professions, Omaha, NE 68178, USA
    Indian J Exp Biol 40:717-26. 2002
    ....