TODD E LENCZ

Summary

Affiliation: Long Island Jewish Medical Center
Country: USA

Publications

  1. ncbi Implications for health and disease in the genetic signature of the Ashkenazi Jewish population
    Saurav Guha
    Department of Psychiatry, Division of Research, The Zucker Hillside Hospital Division of the North Shore Long Island Jewish Health System, 75 59, 263rd St Glen Oaks, NY 11004, USA
    Genome Biol 13:R2. 2012
  2. ncbi The assessment of "prodromal schizophrenia": unresolved issues and future directions
    Todd Lencz
    Albert Einstein College of Medicine, Bronx, NY, USA
    Schizophr Bull 29:717-28. 2003
  3. ncbi Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia
    T Lencz
    Department of Psychiatry Research, The Zucker Hillside Hospital, Division of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Mol Psychiatry 12:572-80. 2007
  4. ncbi Runs of homozygosity reveal highly penetrant recessive loci in schizophrenia
    Todd Lencz
    Department of Psychiatry Research, Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Proc Natl Acad Sci U S A 104:19942-7. 2007
  5. ncbi DRD2 promoter region variation as a predictor of sustained response to antipsychotic medication in first-episode schizophrenia patients
    Todd Lencz
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Am J Psychiatry 163:529-31. 2006
  6. ncbi Generalized and specific neurocognitive deficits in prodromal schizophrenia
    Todd Lencz
    Recognition and Prevention Program, Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York, USA
    Biol Psychiatry 59:863-71. 2006
  7. ncbi Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes
    Todd Lencz
    The Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd Street, Glen Oaks, New York 11004, USA
    Br J Psychiatry 194:313-8. 2009
  8. ncbi Nonspecific and attenuated negative symptoms in patients at clinical high-risk for schizophrenia
    Todd Lencz
    Recognition and Prevention Program, Lake Success, NY 11042, USA
    Schizophr Res 68:37-48. 2004
  9. ncbi Impairments in perceptual competency and maintenance on a visual delayed match-to-sample test in first-episode schizophrenia
    Todd Lencz
    Department of Psychiatry, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Arch Gen Psychiatry 60:238-43. 2003
  10. ncbi Neurodevelopmental models of schizophrenia: pathophysiologic synthesis and directions for intervention research
    T Lencz
    Division of High Risk Studies, Hillside Hospital, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Psychopharmacol Bull 35:95-125. 2001

Research Grants

  1. Identifying & Characterizing Prodromal Schizophrenia
    Todd Lencz; Fiscal Year: 2007
  2. Identifying Molecular Subtypes of Schizophrenia: A Novel Genomic Approach
    Todd Lencz; Fiscal Year: 2009
  3. Identifying Molecular Subtypes of Schizophrenia: A Novel Genomic Approach
    Todd Lencz; Fiscal Year: 2010

Detail Information

Publications51

  1. ncbi Implications for health and disease in the genetic signature of the Ashkenazi Jewish population
    Saurav Guha
    Department of Psychiatry, Division of Research, The Zucker Hillside Hospital Division of the North Shore Long Island Jewish Health System, 75 59, 263rd St Glen Oaks, NY 11004, USA
    Genome Biol 13:R2. 2012
    ..Comparison of the genotyping data with that of neighboring European and Asian populations enabled the Ashkenazi Jewish-specific component of the variance to be characterized with respect to disease-relevant alleles and pathways...
  2. ncbi The assessment of "prodromal schizophrenia": unresolved issues and future directions
    Todd Lencz
    Albert Einstein College of Medicine, Bronx, NY, USA
    Schizophr Bull 29:717-28. 2003
    ..The dimensional quantification of prodromal symptom severity may be an important direction for future studies of the assessment of at-risk states...
  3. ncbi Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia
    T Lencz
    Department of Psychiatry Research, The Zucker Hillside Hospital, Division of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Mol Psychiatry 12:572-80. 2007
    ..The presence of cytokine receptor abnormalities in schizophrenia may help explain prior epidemiologic data relating the risk for this illness to altered rates of autoimmune disorders, prenatal infection and familial leukemia...
  4. ncbi Runs of homozygosity reveal highly penetrant recessive loci in schizophrenia
    Todd Lencz
    Department of Psychiatry Research, Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Proc Natl Acad Sci U S A 104:19942-7. 2007
    ..Other risk ROHs feature haplotypes that are also common in healthy individuals, possibly indicating a source of balancing selection...
  5. ncbi DRD2 promoter region variation as a predictor of sustained response to antipsychotic medication in first-episode schizophrenia patients
    Todd Lencz
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Am J Psychiatry 163:529-31. 2006
    ....
  6. ncbi Generalized and specific neurocognitive deficits in prodromal schizophrenia
    Todd Lencz
    Recognition and Prevention Program, Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York, USA
    Biol Psychiatry 59:863-71. 2006
    ..The present study examined performance on a broad neuropsychological battery of young subjects considered to be at clinical high risk for schizophrenia, who were subsequently followed to determine clinical outcome...
  7. ncbi Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes
    Todd Lencz
    The Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd Street, Glen Oaks, New York 11004, USA
    Br J Psychiatry 194:313-8. 2009
    ..Brain-derived neurotrophic factor variants may help clarify the status of schizoaffective disorder...
  8. ncbi Nonspecific and attenuated negative symptoms in patients at clinical high-risk for schizophrenia
    Todd Lencz
    Recognition and Prevention Program, Lake Success, NY 11042, USA
    Schizophr Res 68:37-48. 2004
    ....
  9. ncbi Impairments in perceptual competency and maintenance on a visual delayed match-to-sample test in first-episode schizophrenia
    Todd Lencz
    Department of Psychiatry, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Arch Gen Psychiatry 60:238-43. 2003
    ..It was hypothesized that patients in the first episode of schizophrenia would exhibit dissociable deficits in both WM domains...
  10. ncbi Neurodevelopmental models of schizophrenia: pathophysiologic synthesis and directions for intervention research
    T Lencz
    Division of High Risk Studies, Hillside Hospital, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Psychopharmacol Bull 35:95-125. 2001
    ..Such information could have significant implications in terms of understanding the prediction, treatment, and, ultimately, prevention of schizophrenia...
  11. ncbi A schizophrenia risk gene, ZNF804A, influences neuroanatomical and neurocognitive phenotypes
    Todd Lencz
    Department of Psychiatry, Division of Research, The Zucker Hillside Hospital Division of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 35:2284-91. 2010
    ..05). The risk allele dosage also predicted impairments on a timed visuomotor performance task (trails A). Results support a role of ZNF804A in phenotypes reflecting altered neural connectivity...
  12. ncbi DRD2 promoter region variation predicts antipsychotic-induced weight gain in first episode schizophrenia
    Todd Lencz
    Division of Psychiatry Research, The Zucker Hillside Hospital, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Pharmacogenet Genomics 20:569-72. 2010
    ..Given earlier evidence that deletion carriers show reduced symptom response to medication, additional study of appropriate treatment options for these patients seems warranted...
  13. ncbi Genetic variation in the DAOA gene complex: impact on susceptibility for schizophrenia and on cognitive performance
    Carolin Opgen-Rhein
    Division of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, United States
    Schizophr Res 103:169-77. 2008
    ..Our aim in this study was to investigate the relationship between DAOA variation and schizophrenia, and the influence of DAOA on cognitive performance...
  14. ncbi Lack of an inverse relationship between duration of untreated psychosis and cognitive function in first episode schizophrenia
    Terry E Goldberg
    Psychiatry Research, Zucker Hillside Hospital, United States
    Schizophr Res 107:262-6. 2009
    ..Furthermore, assuming that cognition is a core symptom of schizophrenia, the notion that ongoing psychosis is somehow toxic for a variety of information processing domains appears questionable...
  15. ncbi Patterns of stress in schizophrenia
    Julia D Betensky
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Psychiatry Res 160:38-46. 2008
    ....
  16. ncbi D2 receptor genetic variation and clinical response to antipsychotic drug treatment: a meta-analysis
    Jian Ping Zhang
    Division of Psychiatry Research, Department of Psychiatry, The Zucker Hillside Hospital, 75 59 263rd St, Glen Oaks, NY 11004, USA
    Am J Psychiatry 167:763-72. 2010
    ..The authors conducted the first meta-analysis to examine the relationship between DRD2 polymorphisms and antipsychotic drug response...
  17. ncbi Cognitive improvement after treatment with second-generation antipsychotic medications in first-episode schizophrenia: is it a practice effect?
    Terry E Goldberg
    Zucker Hillside Hospital, 7559 263rd Street, Glen Oaks, NY 11004, USA
    Arch Gen Psychiatry 64:1115-22. 2007
    ..However, none of these studies included healthy controls undergoing repeated testing to assess the possibility that improvements might reflect simple practice effects...
  18. ncbi Neurocognitive profile in adolescents with early-onset schizophrenia: clinical correlates
    Joseph P Rhinewine
    Department of Psychiatry Research Zucker Hillside Hospital, Glen Oaks, New York 11004, USA
    Biol Psychiatry 58:705-12. 2005
    ..The overall pattern is similar to that observed in severely ill first-episode adult patients. The impairments across multiple neurocognitive domains suggest widespread brain dysfunction in EOS...
  19. ncbi Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 33:976-84. 2008
    ..These abnormalities have clinical and neuropsychological correlates, which may be useful in further characterizing structure-function relations in schizophrenia and constraining neurobiological models of the disorder...
  20. ncbi Pharmacogenetics of antipsychotic-induced side effects
    Todd Lencz
    Center for Translational Psychiatry, Feinstein Institute for Medical Research, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Dialogues Clin Neurosci 11:405-15. 2009
    ..Effects of these genes and others on risk for TD, extrapyramidal side effects, hyperprolactinemia, and weight gain are reviewed in this article...
  21. ncbi DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia
    Philip R Szeszko
    Feinstein Institute for Medical Research, Manhasset, NY, USA
    Biol Psychol 79:103-10. 2008
    ..Given that DISC1 plays a role in cerebral cortex development, polymorphisms in this gene may have relevance for neurobiological models of schizophrenia that have implicated cortical deficits in its pathophysiology...
  22. ncbi Deficits in memory strategy use are related to verbal memory impairments in adolescents with schizophrenia-spectrum disorders
    David Roofeh
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Schizophr Res 85:201-12. 2006
    ..To assess the nature of learning and verbal memory deficits in adolescents with schizophrenia-spectrum disorders (SzS) (i.e., schizophrenia, schizoaffective disorder, and schizophreniform disorder)...
  23. ncbi Gray matter structural alterations in psychotropic drug-naive pediatric obsessive-compulsive disorder: an optimized voxel-based morphometry study
    Philip R Szeszko
    Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd St, Glen Oaks, NY 11004, USA
    Am J Psychiatry 165:1299-307. 2008
    ....
  24. ncbi Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding
    Katherine E Burdick
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Hum Mol Genet 17:2462-73. 2008
    ..These data suggest that NDEL1 significantly influences risk for SZ via an interaction with DISC1. We propose a model where NDEL1 and NDE1 compete for binding with DISC1...
  25. ncbi The genetics of symptom-based phenotypes: toward a molecular classification of schizophrenia
    Pamela DeRosse
    Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, NY, USA
    Schizophr Bull 34:1047-53. 2008
    ..We examined these chromosomal regions for association to positive, negative, and disorganized symptom clusters, using a dense set of single-nucleotide polymorphisms (SNPs)...
  26. ncbi Predictors of remission, schizophrenia, and bipolar disorder in adolescents with brief psychotic disorder or psychotic disorder not otherwise specified considered at very high risk for schizophrenia
    Christoph U Correll
    The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    J Child Adolesc Psychopharmacol 18:475-90. 2008
    ....
  27. ncbi Gray matter structural alterations in obsessive-compulsive disorder: relationship to neuropsychological functions
    Christopher J Christian
    Zucker Hillside Hospital, Psychiatry Research, Glen Oaks, NY, United States
    Psychiatry Res 164:123-31. 2008
    ..Moreover, our data suggest that gray matter structural alterations in OCD have neuropsychological correlates, which may be useful in further characterizing structure-function relations in this disorder...
  28. ncbi Lower orbital frontal white matter integrity in adolescents with bipolar I disorder
    Vivian Kafantaris
    Feinstein Institute for Medical Research, North Shore Long Island Jewish Health System
    J Am Acad Child Adolesc Psychiatry 48:79-86. 2009
    ..To examine white matter microstructure, as assessed via diffusion tensor imaging (DTI), in adolescents with bipolar I disorder compared with control volunteers...
  29. ncbi Association of genetic variation in the MET proto-oncogene with schizophrenia and general cognitive ability
    Katherine E Burdick
    Hillside Hospital, North Shore Long Island Jewish Health System, Department of Psychiatry Research, Glen Oaks, NY 11004, USA
    Am J Psychiatry 167:436-43. 2010
    ..Thus, MET may be of particular interest as a candidate gene for neuropsychiatric diseases with a developmental etiology, including schizophrenia...
  30. ncbi The schizophrenia prodrome: treatment and high-risk perspectives
    Barbara Cornblatt
    Department of Psychiatry Research, Hillside Hospital of the North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Schizophr Res 54:177-86. 2002
    ..Depending upon clinical characteristics and phase of the prodrome, anti-depressants also appear highly effective...
  31. ncbi Cannabis use disorders in schizophrenia: effects on cognition and symptoms
    Pamela DeRosse
    Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, NY, USA
    Schizophr Res 120:95-100. 2010
    ..Although several studies have suggested that CUD in patients with SZ may be associated with variation in cognitive function, clinical presentation and course of illness, the effects have been inconsistent...
  32. ncbi Genomics and the future of pharmacotherapy in psychiatry
    Anil K Malhotra
    Division of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Int Rev Psychiatry 19:523-30. 2007
    ..These increasingly comprehensive approaches should provide informative data on the genes associated with psychotropic drug response, a critical step towards the ultimate goal of 'personalized' medicine...
  33. ncbi Overview of the First Annual Workshop on the Schizophrenia Prodrome
    Andrea M Auther
    Recognition and Prevention Program, Zucker Hillside Hospital, USA
    Schizophr Bull 29:625-31. 2003
    ..Two additional results were the decision to hold similar workshops in the future and the formation of the International Prodromal Research Network to foster international multisite collaborations...
  34. ncbi The schizophrenia prodrome revisited: a neurodevelopmental perspective
    Barbara A Cornblatt
    Albert Einstein College of Medicine, Bronx, NY, USA
    Schizophr Bull 29:633-51. 2003
    ..We conclude that a neurodevelopmental model of schizophrenia is supported by our data and that a range of novel treatment strategies may be neuroprotective by directly affecting the disorder's vulnerability core...
  35. ncbi Left middle temporal gyrus activation during a phonemic discrimination task
    Manzar Ashtari
    Department of Radiology, North Shore Long Island Jewish Health System, New Hyde Park, NY 11004, USA
    Neuroreport 15:389-93. 2004
    ..This study also demonstrates the advantage of tone discrimination control blocks as opposed to conventional rest periods to isolate the pure language component of phonemic discrimination...
  36. ncbi DISC1 and neurocognitive function in schizophrenia
    Katherine E Burdick
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York, USA
    Neuroreport 16:1399-402. 2005
    ..These data suggest that DISC1 is associated with neurocognitive functioning in schizophrenia...
  37. ncbi Prospective study of adolescents with subsyndromal psychosis: characteristics and outcome
    Christoph U Correll
    The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    J Child Adolesc Psychopharmacol 15:418-33. 2005
    ..The aim of this study was to examine the characteristics and outcome of adolescents with psychotic disorder not otherwise specified (PsyNOS) and brief psychotic disorder (BrPsy), two neglected subsyndromal diagnostic entities...
  38. ncbi White matter abnormalities in early-onset schizophrenia: a voxel-based diffusion tensor imaging study
    Sanjiv Kumra
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    J Am Acad Child Adolesc Psychiatry 44:934-41. 2005
    ..To investigate abnormalities in the structural integrity of brain white matter as suggested by diffusion tensor imaging in adolescents with early-onset schizophrenia (onset of psychosis by age 18)...
  39. ncbi Early-onset schizophrenia is associated with impaired adolescent development of attentional capacity using the identical pairs continuous performance test
    Emily Thaden
    The Zucker Hillside Hospital, Department of Psychiatry Research 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Schizophr Res 81:157-66. 2006
    ....
  40. ncbi Genetic variation in DTNBP1 influences general cognitive ability
    Katherine E Burdick
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Albert Einstein College of Medicine, Glen Oaks, NY 11004, USA
    Hum Mol Genet 15:1563-8. 2006
    ..These data suggest that DTNBP1 genetic variation influences human intelligence...
  41. ncbi Dysbindin genotype and negative symptoms in schizophrenia
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Am J Psychiatry 163:532-4. 2006
    ....
  42. ncbi Early identification and high-risk strategies for bipolar disorder
    Christoph U Correll
    The Zucker Hillside Hospital, Psychiatry Research, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Bipolar Disord 9:324-38. 2007
    ..To describe and compare the relative merits of different identification strategies for individuals at risk for bipolar disorder (BPD)...
  43. ncbi Can antidepressants be used to treat the schizophrenia prodrome? Results of a prospective, naturalistic treatment study of adolescents
    Barbara A Cornblatt
    Recognition and Prevention RAP Program, Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    J Clin Psychiatry 68:546-57. 2007
    ..This study reports the results of a prospective, naturalistic treatment study of adolescents considered to be in the prodromal (i.e., prepsychotic) phase of schizophrenia...
  44. ncbi Anterior cingulate grey-matter deficits and cannabis use in first-episode schizophrenia
    Philip R Szeszko
    Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Br J Psychiatry 190:230-6. 2007
    ..Despite the high prevalence of cannabis use in schizophrenia, few studies have examined the potential relationship between cannabis exposure and brain structural abnormalities in schizophrenia...
  45. ncbi Increased stress and smaller anterior hippocampal volume
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Neuroreport 17:1825-8. 2006
    ..Our results may also have implications for neuropsychiatric disorders that have implicated stress and hippocampal abnormalities in their pathogenesis...
  46. ncbi DTNBP1 genotype influences cognitive decline in schizophrenia
    Katherine E Burdick
    Division of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, United States
    Schizophr Res 89:169-72. 2007
    ..The current study assessed the relationship between intellectual decline in schizophrenia and genetic variation in dysbindin-1 (DTNBP1)...
  47. ncbi Disrupted in schizophrenia 1 genotype and positive symptoms in schizophrenia
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Biol Psychiatry 61:1208-10. 2007
    ....
  48. ncbi COMT genotype and manic symptoms in schizophrenia
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, and Harvard Partners Center for Genetics and Genomics, Boston, MA, United States
    Schizophr Res 87:28-31. 2006
    ..These data suggest that the effect of COMT variation may be associated with comorbid manic symptoms in SZ...
  49. ncbi Smaller anterior hippocampal formation volume in antipsychotic-naive patients with first-episode schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, 75 59 263rd St, Glen Oaks, NY 11004, USA
    Am J Psychiatry 160:2190-7. 2003
    ..The authors investigated volumetric alterations of the anterior hippocampal formation in patients experiencing a first episode of schizophrenia relative to healthy comparison subjects...
  50. ncbi Brain morphometry using diffusion-weighted magnetic resonance imaging: application to schizophrenia
    Babak A Ardekani
    Center for Advanced Brain Imaging, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York, USA
    Neuroreport 16:1455-9. 2005
    ..Affected areas included the bilateral insular cortex, hippocampus, temporal lobe, and occipital areas. These results largely concur with previous findings of cortical volume deficits in schizophrenia...
  51. ncbi Novel multi-nucleotide polymorphisms in the human genome characterized by whole genome and exome sequencing
    Jeffrey A Rosenfeld
    Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, USA
    Nucleic Acids Res 38:6102-11. 2010
    ..We have found a TNP causing a single amino acid change in LAMC2 and a TNP causing a truncation of HUWE1...

Research Grants4

  1. Identifying & Characterizing Prodromal Schizophrenia
    Todd Lencz; Fiscal Year: 2007
    ..This study will provide the candidate with the knowledge and research experience necessary to apply for an R01 to expand upon this research from a neurodevelopmental perspective. ..
  2. Identifying Molecular Subtypes of Schizophrenia: A Novel Genomic Approach
    Todd Lencz; Fiscal Year: 2009
    ..Findings will create new opportunities for diagnosis and prediction of schizophrenia, and for understanding its biology. ..
  3. Identifying Molecular Subtypes of Schizophrenia: A Novel Genomic Approach
    Todd Lencz; Fiscal Year: 2010
    ..Findings will create new opportunities for diagnosis and prediction of schizophrenia, and for understanding its biology. ..