Research Topics
Genomes and GenesSpecies | Pamela DeRosseSummaryAffiliation: Long Island Jewish Medical Center Country: USA Publications
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Detail Information
Publications
Molecular genetics of the psychosis phenotypePamela DeRosse
Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA
Can J Psychiatry 57:446-53. 2012....
Cannabis use disorders in schizophrenia: effects on cognition and symptomsPamela DeRosse
Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, NY, USA
Schizophr Res 120:95-100. 2010..Although several studies have suggested that CUD in patients with SZ may be associated with variation in cognitive function, clinical presentation and course of illness, the effects have been inconsistent...
Dysbindin genotype and negative symptoms in schizophreniaPamela DeRosse
Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
Am J Psychiatry 163:532-4. 2006....
Interferon-induced obsessive-compulsive disorderPamela DeRosse
Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, NY 11004, USA
Gen Hosp Psychiatry 28:357-8. 2006
COMT genotype and manic symptoms in schizophreniaPamela DeRosse
Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, and Harvard Partners Center for Genetics and Genomics, Boston, MA, United States
Schizophr Res 87:28-31. 2006..These data suggest that the effect of COMT variation may be associated with comorbid manic symptoms in SZ...
Disrupted in schizophrenia 1 genotype and positive symptoms in schizophreniaPamela DeRosse
Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
Biol Psychiatry 61:1208-10. 2007....
The genetics of symptom-based phenotypes: toward a molecular classification of schizophreniaPamela DeRosse
Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, NY, USA
Schizophr Bull 34:1047-53. 2008..We examined these chromosomal regions for association to positive, negative, and disorganized symptom clusters, using a dense set of single-nucleotide polymorphisms (SNPs)...
Genetic variation in the DAOA gene complex: impact on susceptibility for schizophrenia and on cognitive performanceCarolin Opgen-Rhein
Division of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, United States
Schizophr Res 103:169-77. 2008..Our aim in this study was to investigate the relationship between DAOA variation and schizophrenia, and the influence of DAOA on cognitive performance...
Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive bindingKatherine E Burdick
Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
Hum Mol Genet 17:2462-73. 2008..These data suggest that NDEL1 significantly influences risk for SZ via an interaction with DISC1. We propose a model where NDEL1 and NDE1 compete for binding with DISC1...
Association of genetic variation in the MET proto-oncogene with schizophrenia and general cognitive abilityKatherine E Burdick
Hillside Hospital, North Shore Long Island Jewish Health System, Department of Psychiatry Research, Glen Oaks, NY 11004, USA
Am J Psychiatry 167:436-43. 2010..Thus, MET may be of particular interest as a candidate gene for neuropsychiatric diseases with a developmental etiology, including schizophrenia...
Runs of homozygosity reveal highly penetrant recessive loci in schizophreniaTodd Lencz
Department of Psychiatry Research, Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
Proc Natl Acad Sci U S A 104:19942-7. 2007..Other risk ROHs feature haplotypes that are also common in healthy individuals, possibly indicating a source of balancing selection...
Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypesTodd Lencz
The Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd Street, Glen Oaks, New York 11004, USA
Br J Psychiatry 194:313-8. 2009..Brain-derived neurotrophic factor variants may help clarify the status of schizoaffective disorder...
DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophreniaPhilip R Szeszko
Feinstein Institute for Medical Research, Manhasset, NY, USA
Biol Psychol 79:103-10. 2008..Given that DISC1 plays a role in cerebral cortex development, polymorphisms in this gene may have relevance for neurobiological models of schizophrenia that have implicated cortical deficits in its pathophysiology...
Association of the DTNBP1 locus with schizophrenia in a U.S. populationBirgit Funke
Harvard Medical School Partners Center for Genetics and Genomics, Boston, MA 02115, USA
Am J Hum Genet 75:891-8. 2004..005). Our study provides further evidence for a role of the DTNBP1 gene in the genetic etiology of schizophrenia...
A schizophrenia risk gene, ZNF804A, influences neuroanatomical and neurocognitive phenotypesTodd Lencz
Department of Psychiatry, Division of Research, The Zucker Hillside Hospital Division of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
Neuropsychopharmacology 35:2284-91. 2010..05). The risk allele dosage also predicted impairments on a timed visuomotor performance task (trails A). Results support a role of ZNF804A in phenotypes reflecting altered neural connectivity...
The MATRICS consensus cognitive battery in patients with bipolar I disorderKatherine E Burdick
Department of Psychiatry, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
Neuropsychopharmacology 36:1587-92. 2011..Additional studies should address important psychometric features such as repeatability and potential practice and/or ceiling effects...
Analysis of TBX1 variation in patients with psychotic and affective disordersBirgit H Funke
Harvard Partners Center for Genetics and Genomics, Boston, MA 02139, USA
Mol Med 13:407-14. 2007..Based on these results we conclude that TBX1 variation does not make a strong contribution to the genetic etiology of nonsyndromic forms of psychiatric disorders commonly seen in patients with 22q11DS...
Cognitive and symptomatic predictors of functional disability in schizophreniaSyed Shamsi
Department of Psychiatry, Division of Psychiatry Research, Glen Oaks, NY 11004, United States
Schizophr Res 126:257-64. 2011..Few studies have assessed the relationship between functional outcomes and the MATRICS consensus cognition battery (MCCB), which will be central to future clinical trials of cognitive enhancing agents...
Emotional modulation of response inhibition in stable patients with bipolar I disorder: a comparison with healthy and schizophrenia subjectsChaya B Gopin
Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
Bipolar Disord 13:164-72. 2011..We examined the pattern of affective processing in stable BD patients and compared their profile to that of healthy controls (HC) and patients diagnosed with schizophrenia (SZ)...
A voxel-based diffusion tensor imaging study of white matter in bipolar disorderKatie Mahon
Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
Neuropsychopharmacology 34:1590-600. 2009..Our findings are consistent with models of bipolar disorder that implicate dysregulation of cortico-subcortical and cerebellar regions in the disorder and may have relevance for phenomenology...
Genetic variation in BDNF is associated with antipsychotic treatment resistance in patients with schizophreniaJian Ping Zhang
Department of Psychiatry, Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY, United States Feinstein Institute for Medical Research, North Shore Long Island Jewish Health System, Manhasset, NY, United States Electronic address
Schizophr Res 146:285-8. 2013..In the present study, we utilized this phenotype to test previously-identified candidate genes for antipsychotic treatment response...
Cognitive and clinical outcomes associated with cannabis use in patients with bipolar I disorderRaphael J Braga
The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Department of Psychiatry Research, Glen Oaks, NY, USA
Psychiatry Res 200:242-5. 2012..Interestingly, bipolar patients with history of CUD had better neurocognitive performance as compared to patients with no history of CUD...
The contextually controlled, feature-mediated classification of symbolsPamela DeRosse
The Zucker Hillside Hospital of the North Shore LIJ Health System, Glen Oaks, NY 11004, USA
J Exp Anal Behav 93:225-45. 2010..These data describe one set of conditions that could account for the establishment of complex classification repertoires that occur in natural settings...
White matter development in adolescence: diffusion tensor imaging and meta-analytic resultsBart D Peters
Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA
Schizophr Bull 38:1308-17. 2012..However, the WM tracts that show FA increases have been variable across studies. Here, we aimed to assess which WM tracts show the most pronounced changes across adolescence...
The FEZ1 gene shows no association to schizophrenia in Caucasian or African American populationsColin A Hodgkinson
Section of Human Neurogenetics, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA
Neuropsychopharmacology 32:190-6. 2007..Neuropsychopharmacology (2007) 32, 190-196. doi:10.1038/sj.npp.1301177; published online 16 August 2006...
