Pamela DeRosse

Summary

Affiliation: Long Island Jewish Medical Center
Country: USA

Publications

  1. pmc Empirical support for DSM-IV schizoaffective disorder: clinical and cognitive validators from a large patient sample
    Pamela DeRosse
    Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, New York, USA
    PLoS ONE 8:e63734. 2013
  2. ncbi request reprint Molecular genetics of the psychosis phenotype
    Pamela DeRosse
    Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA
    Can J Psychiatry 57:446-53. 2012
  3. pmc Cannabis use disorders in schizophrenia: effects on cognition and symptoms
    Pamela DeRosse
    Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, NY, USA
    Schizophr Res 120:95-100. 2010
  4. pmc The genetics of symptom-based phenotypes: toward a molecular classification of schizophrenia
    Pamela DeRosse
    Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, NY, USA
    Schizophr Bull 34:1047-53. 2008
  5. ncbi request reprint Disrupted in schizophrenia 1 genotype and positive symptoms in schizophrenia
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Biol Psychiatry 61:1208-10. 2007
  6. ncbi request reprint COMT genotype and manic symptoms in schizophrenia
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, and Harvard Partners Center for Genetics and Genomics, Boston, MA, United States
    Schizophr Res 87:28-31. 2006
  7. ncbi request reprint Interferon-induced obsessive-compulsive disorder
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Gen Hosp Psychiatry 28:357-8. 2006
  8. ncbi request reprint Dysbindin genotype and negative symptoms in schizophrenia
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Am J Psychiatry 163:532-4. 2006
  9. pmc Genetic variation in the DAOA gene complex: impact on susceptibility for schizophrenia and on cognitive performance
    Carolin Opgen-Rhein
    Division of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, United States
    Schizophr Res 103:169-77. 2008
  10. pmc Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding
    Katherine E Burdick
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Hum Mol Genet 17:2462-73. 2008

Detail Information

Publications31

  1. pmc Empirical support for DSM-IV schizoaffective disorder: clinical and cognitive validators from a large patient sample
    Pamela DeRosse
    Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, New York, USA
    PLoS ONE 8:e63734. 2013
    ....
  2. ncbi request reprint Molecular genetics of the psychosis phenotype
    Pamela DeRosse
    Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA
    Can J Psychiatry 57:446-53. 2012
    ....
  3. pmc Cannabis use disorders in schizophrenia: effects on cognition and symptoms
    Pamela DeRosse
    Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, NY, USA
    Schizophr Res 120:95-100. 2010
    ..Although several studies have suggested that CUD in patients with SZ may be associated with variation in cognitive function, clinical presentation and course of illness, the effects have been inconsistent...
  4. pmc The genetics of symptom-based phenotypes: toward a molecular classification of schizophrenia
    Pamela DeRosse
    Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, NY, USA
    Schizophr Bull 34:1047-53. 2008
    ..We examined these chromosomal regions for association to positive, negative, and disorganized symptom clusters, using a dense set of single-nucleotide polymorphisms (SNPs)...
  5. ncbi request reprint Disrupted in schizophrenia 1 genotype and positive symptoms in schizophrenia
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Biol Psychiatry 61:1208-10. 2007
    ....
  6. ncbi request reprint COMT genotype and manic symptoms in schizophrenia
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, and Harvard Partners Center for Genetics and Genomics, Boston, MA, United States
    Schizophr Res 87:28-31. 2006
    ..These data suggest that the effect of COMT variation may be associated with comorbid manic symptoms in SZ...
  7. ncbi request reprint Interferon-induced obsessive-compulsive disorder
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Gen Hosp Psychiatry 28:357-8. 2006
  8. ncbi request reprint Dysbindin genotype and negative symptoms in schizophrenia
    Pamela DeRosse
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Am J Psychiatry 163:532-4. 2006
    ....
  9. pmc Genetic variation in the DAOA gene complex: impact on susceptibility for schizophrenia and on cognitive performance
    Carolin Opgen-Rhein
    Division of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, United States
    Schizophr Res 103:169-77. 2008
    ..Our aim in this study was to investigate the relationship between DAOA variation and schizophrenia, and the influence of DAOA on cognitive performance...
  10. pmc Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding
    Katherine E Burdick
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Hum Mol Genet 17:2462-73. 2008
    ..These data suggest that NDEL1 significantly influences risk for SZ via an interaction with DISC1. We propose a model where NDEL1 and NDE1 compete for binding with DISC1...
  11. pmc Association of genetic variation in the MET proto-oncogene with schizophrenia and general cognitive ability
    Katherine E Burdick
    Hillside Hospital, North Shore Long Island Jewish Health System, Department of Psychiatry Research, Glen Oaks, NY 11004, USA
    Am J Psychiatry 167:436-43. 2010
    ..Thus, MET may be of particular interest as a candidate gene for neuropsychiatric diseases with a developmental etiology, including schizophrenia...
  12. pmc Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes
    Todd Lencz
    The Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd Street, Glen Oaks, New York 11004, USA
    Br J Psychiatry 194:313-8. 2009
    ..Brain-derived neurotrophic factor variants may help clarify the status of schizoaffective disorder...
  13. pmc Runs of homozygosity reveal highly penetrant recessive loci in schizophrenia
    Todd Lencz
    Department of Psychiatry Research, Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Proc Natl Acad Sci U S A 104:19942-7. 2007
    ..Other risk ROHs feature haplotypes that are also common in healthy individuals, possibly indicating a source of balancing selection...
  14. pmc DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia
    Philip R Szeszko
    Feinstein Institute for Medical Research, Manhasset, NY, USA
    Biol Psychol 79:103-10. 2008
    ..Given that DISC1 plays a role in cerebral cortex development, polymorphisms in this gene may have relevance for neurobiological models of schizophrenia that have implicated cortical deficits in its pathophysiology...
  15. pmc A schizophrenia risk gene, ZNF804A, influences neuroanatomical and neurocognitive phenotypes
    Todd Lencz
    Department of Psychiatry, Division of Research, The Zucker Hillside Hospital Division of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 35:2284-91. 2010
    ..05). The risk allele dosage also predicted impairments on a timed visuomotor performance task (trails A). Results support a role of ZNF804A in phenotypes reflecting altered neural connectivity...
  16. pmc Association of the DTNBP1 locus with schizophrenia in a U.S. population
    Birgit Funke
    Harvard Medical School Partners Center for Genetics and Genomics, Boston, MA 02115, USA
    Am J Hum Genet 75:891-8. 2004
    ..005). Our study provides further evidence for a role of the DTNBP1 gene in the genetic etiology of schizophrenia...
  17. doi request reprint Cognitive and clinical outcomes associated with cannabis use in patients with bipolar I disorder
    Raphael J Braga
    The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Department of Psychiatry Research, Glen Oaks, NY, USA
    Psychiatry Res 200:242-5. 2012
    ..Interestingly, bipolar patients with history of CUD had better neurocognitive performance as compared to patients with no history of CUD...
  18. pmc The MATRICS consensus cognitive battery in patients with bipolar I disorder
    Katherine E Burdick
    Department of Psychiatry, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 36:1587-92. 2011
    ..Additional studies should address important psychometric features such as repeatability and potential practice and/or ceiling effects...
  19. pmc Analysis of TBX1 variation in patients with psychotic and affective disorders
    Birgit H Funke
    Harvard Partners Center for Genetics and Genomics, Boston, MA 02139, USA
    Mol Med 13:407-14. 2007
    ..Based on these results we conclude that TBX1 variation does not make a strong contribution to the genetic etiology of nonsyndromic forms of psychiatric disorders commonly seen in patients with 22q11DS...
  20. pmc Cognitive and symptomatic predictors of functional disability in schizophrenia
    Syed Shamsi
    Department of Psychiatry, Division of Psychiatry Research, Glen Oaks, NY 11004, United States
    Schizophr Res 126:257-64. 2011
    ..Few studies have assessed the relationship between functional outcomes and the MATRICS consensus cognition battery (MCCB), which will be central to future clinical trials of cognitive enhancing agents...
  21. pmc Sex differences in resilience to childhood maltreatment: effects of trauma history on hippocampal volume, general cognition and subclinical psychosis in healthy adults
    Erin Samplin
    Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, NY, USA
    J Psychiatr Res 47:1174-9. 2013
    ..Further research is needed to elucidate the mechanisms involved in these different levels of resilience. ..
  22. doi request reprint Age-related differences in white matter tract microstructure are associated with cognitive performance from childhood to adulthood
    Bart D Peters
    Division of Psychiatry Research BDP, TI, PD, MJ, PRS, AKM, Zucker Hillside Hospital, Glen Oaks, New York Center for Psychiatric Neuroscience BDP, TI, PD, MJ, PRS, AKM, Feinstein Institute for Medical Research, Manhasset, New York Electronic address
    Biol Psychiatry 75:248-56. 2014
    ..In the present cross-sectional study, we examined whether these differences are associated with neurocognitive performance from childhood to late adulthood...
  23. pmc Genetic variation in BDNF is associated with antipsychotic treatment resistance in patients with schizophrenia
    Jian Ping Zhang
    Department of Psychiatry, Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, United States
    Schizophr Res 146:285-8. 2013
    ..In the present study, we utilized this phenotype to test previously-identified candidate genes for antipsychotic treatment response...
  24. pmc Emotional modulation of response inhibition in stable patients with bipolar I disorder: a comparison with healthy and schizophrenia subjects
    Chaya B Gopin
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Bipolar Disord 13:164-72. 2011
    ..We examined the pattern of affective processing in stable BD patients and compared their profile to that of healthy controls (HC) and patients diagnosed with schizophrenia (SZ)...
  25. pmc Resting-state FMRI connectivity impairment in schizophrenia and bipolar disorder
    Miklos Argyelan
    To whom correspondence should be addressed Psychiatry Research, Zucker Hillside Hospital, North Shore LIJ Health System, 75 59 263rd Street, Glen Oaks, NY 11004, US tel 718 470 4486, fax 718 343 1659, E mail
    Schizophr Bull 40:100-10. 2014
    ..Conclusions: These findings are consistent with the hypothesis that schizophrenia and bipolar disorder may represent a continuum of global disconnectivity in the brain but that regional functional specificity may not be evident. ..
  26. pmc White matter development in adolescence: diffusion tensor imaging and meta-analytic results
    Bart D Peters
    Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA
    Schizophr Bull 38:1308-17. 2012
    ..However, the WM tracts that show FA increases have been variable across studies. Here, we aimed to assess which WM tracts show the most pronounced changes across adolescence...
  27. pmc A voxel-based diffusion tensor imaging study of white matter in bipolar disorder
    Katie Mahon
    Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 34:1590-600. 2009
    ..Our findings are consistent with models of bipolar disorder that implicate dysregulation of cortico-subcortical and cerebellar regions in the disorder and may have relevance for phenomenology...
  28. pmc Judgements of agency in schizophrenia: an impairment in autonoetic metacognition
    Janet Metcalfe
    Department of Psychology, Columbia University, 1190 Amsterdam Avenue, New York, NY 10027, USA
    Philos Trans R Soc Lond B Biol Sci 367:1391-400. 2012
    ....
  29. pmc The contextually controlled, feature-mediated classification of symbols
    Pamela DeRosse
    The Zucker Hillside Hospital of the North Shore LIJ Health System, Glen Oaks, NY 11004, USA
    J Exp Anal Behav 93:225-45. 2010
    ..These data describe one set of conditions that could account for the establishment of complex classification repertoires that occur in natural settings...
  30. doi request reprint Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder
    Todd Lencz
    1 Division of Research, Department of Psychiatry, The Zucker Hillside Hospital Division of the North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA 2 Center for Psychiatric Neuroscience, The Feinstein Institute for Medical Research, Manhasset, New York 11030, USA 3 Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461, USA 4 Department of Psychiatry, Hofstra University School of Medicine, Hempstead, New York 11550, USA 5 Department of Molecular Medicine, Hofstra University School of Medicine, Hempstead, New York 11550, USA 6
    Nat Commun 4:2739. 2013
    ..Heparan sulphate binding is critical to neurite outgrowth, axon formation and synaptic processes thought to be aberrant in these disorders. ..
  31. ncbi request reprint The FEZ1 gene shows no association to schizophrenia in Caucasian or African American populations
    Colin A Hodgkinson
    Section of Human Neurogenetics, Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA
    Neuropsychopharmacology 32:190-6. 2007
    ..Neuropsychopharmacology (2007) 32, 190-196. doi:10.1038/sj.npp.1301177; published online 16 August 2006...