Shaun M Sheets

Summary

Affiliation: Loma Linda University
Country: USA

Publications

  1. pmc Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cells
    Shaun M Sheets
    Department of Biochemistry and Microbiology, School of Medicine, Loma Linda University, Loma Linda, CA 92350, USA
    Infect Immun 73:1543-52. 2005
  2. pmc Gingipains from Porphyromonas gingivalis W83 synergistically disrupt endothelial cell adhesion and can induce caspase-independent apoptosis
    Shaun M Sheets
    Department of Biochemistry and Microbiology, School of Medicine, Loma Linda University, Loma Linda, CA 92350, USA
    Infect Immun 74:5667-78. 2006
  3. pmc Gingipain-dependent interactions with the host are important for survival of Porphyromonas gingivalis
    Shaun M Sheets
    Department of Biochemistry and Microbiology, School of Medicine, Loma Linda University, Loma Linda, California 92350, USA
    Front Biosci 13:3215-38. 2008
  4. pmc Gingipain RgpB is excreted as a proenzyme in the vimA-defective mutant Porphyromonas gingivalis FLL92
    G Jon Olango
    Division of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350, USA
    Infect Immun 71:3740-7. 2003
  5. ncbi request reprint Antinuclear autoantibodies in prostate cancer: immunity to LEDGF/p75, a survival protein highly expressed in prostate tumors and cleaved during apoptosis
    Tracy Daniels
    Loma Linda University School of Medicine, Department of Biochemistry and Microbiology and Center for Molecular Biology and Gene Therapy, 11085 Campus Street, Loma Linda, CA 92350, USA
    Prostate 62:14-26. 2005

Collaborators

Detail Information

Publications5

  1. pmc Gingipains from Porphyromonas gingivalis W83 induce cell adhesion molecule cleavage and apoptosis in endothelial cells
    Shaun M Sheets
    Department of Biochemistry and Microbiology, School of Medicine, Loma Linda University, Loma Linda, CA 92350, USA
    Infect Immun 73:1543-52. 2005
    ..Taken together, these results indicate that gingipains from P. gingivalis can alter cell adhesion molecules and induce endothelial cell death, which could have implications for the pathogenicity of this organism...
  2. pmc Gingipains from Porphyromonas gingivalis W83 synergistically disrupt endothelial cell adhesion and can induce caspase-independent apoptosis
    Shaun M Sheets
    Department of Biochemistry and Microbiology, School of Medicine, Loma Linda University, Loma Linda, CA 92350, USA
    Infect Immun 74:5667-78. 2006
    ..Degradation of integrin beta1 was inhibited only in the presence of z-VAD-FMK. These results further clarify the role P. gingivalis plays in tissue destruction occurring in the periodontal pocket...
  3. pmc Gingipain-dependent interactions with the host are important for survival of Porphyromonas gingivalis
    Shaun M Sheets
    Department of Biochemistry and Microbiology, School of Medicine, Loma Linda University, Loma Linda, California 92350, USA
    Front Biosci 13:3215-38. 2008
    ..We can postulate a model, in which gingipains may be part of the mechanism for P. gingivalis virulence...
  4. pmc Gingipain RgpB is excreted as a proenzyme in the vimA-defective mutant Porphyromonas gingivalis FLL92
    G Jon Olango
    Division of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350, USA
    Infect Immun 71:3740-7. 2003
    ..In addition, these results provide the first evidence of posttranslational regulation of protease activity in P. gingivalis and may suggest an important role for the vimA gene in protease activation in this organism...
  5. ncbi request reprint Antinuclear autoantibodies in prostate cancer: immunity to LEDGF/p75, a survival protein highly expressed in prostate tumors and cleaved during apoptosis
    Tracy Daniels
    Loma Linda University School of Medicine, Department of Biochemistry and Microbiology and Center for Molecular Biology and Gene Therapy, 11085 Campus Street, Loma Linda, CA 92350, USA
    Prostate 62:14-26. 2005
    ..These autoantibodies represent potentially valuable tools for identifying novel biomarkers and therapeutic targets. This study was designed to identify TAA in prostate cancer (PCa)...