Research Topics
| Gregory A NelsonSummaryAffiliation: Loma Linda University Country: USA Publications
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Publications
Fundamental space radiobiologyGregory A Nelson
Loma Linda University, Loma Linda, CA, USA
Gravit Space Biol Bull 16:29-36. 2003....
Radiation-induced gene expression in the nematode Caenorhabditis elegansGregory A Nelson
Loma Linda University Radiobiology Program, 11175 Campus St, Chan Shun Pavilion A1010 Loma Linda, California 92354, USA
J Radiat Res 43:S199-203. 2002..This suggests that independent homeostatic mechanisms are activated in response to radiation exposure as a function of track structure or ionization density...
Hypergravity-induced immunomodulation in a rodent model: hematological and lymphocyte function analysesMichael J Pecaut
Department of Radiation Medicina, Loma Linda University School of Medicine, Loma Linda, CA 92354, USA
J Appl Physiol 97:29-38. 2004....
Long-term effects of low-dose proton radiation on immunity in mice: shielded vs. unshieldedMichael J Pecaut
Department of Radiation Medicine, Radiobiology Program, Loma Linda University School of Medicine, Loma Linda, CA 92354, USA
Aviat Space Environ Med 74:115-24. 2003..These fields and their biological risks are modified in complex ways by the presence of protective shielding...
Dose and dose rate effects of whole-body proton-irradiation on lymphocyte blastogenesis and hematological variables: part IIMichael J Pecaut
Department of Radiation Medicine, Radiobiology Program, Loma Linda University School of Medicine and Medical Center, Chan Shun Pavilion, Room A 1010, 11175 Campus Street, Loma Linda, CA 92354, USA
Immunol Lett 80:67-73. 2002..A difference, however, was found between protons and gamma-rays in the degree of change induced in some of the measurements...
(56)Fe-particle radiation reduces neuronal output and attenuates lipopolysaccharide-induced inhibition of long-term potentiation in the mouse hippocampusRoman Vlkolinsky
Radiation Medicine, Loma Linda University, Loma Linda, CA 92354, USA
Radiat Res 169:523-30. 2008..Our data show that (56)Fe-particle radiation affects the response of the hippocampus to an immunological stressor and that the alterations progress over time...
Genetic models in applied physiology: selected contribution: effects of spaceflight on immunity in the C57BL/6 mouse. I. Immune population distributionsMichael J Pecaut
Department of Radiation Medicine, Radiobiology Program, Division of Microbiology and Molecular Genetics, Loma Linda University and Medical Center, Loma Linda, California 92354, USA
J Appl Physiol 94:2085-94. 2003..Many of the results are similar to those using other models. Clearly, spaceflight can influence immune parameters ranging from hematopoiesis to mature leukocyte mechanisms...
Behavioral consequences of radiation exposure to simulated space radiation in the C57BL/6 mouse: open field, rotorod, and acoustic startleMichael J Pecaut
Department of Radiation Medicine, Loma Linda University, Loma Linda, California 92350, USA
Cogn Affect Behav Neurosci 2:329-40. 2002..These results suggest that the performance deficits may have been mediated by radiation damage to hippocampal, cerebellar, and possibly, forebrain dopaminergic function...
The effects of low-dose, high-LET radiation exposure on three models of behavior in C57BL/6 miceMichael J Pecaut
Department of a Radiation Medicine, Radiobiology Program, Loma Linda University School of Medicine and Medical Center, Loma Linda, California 92354, USA
Radiat Res 162:148-56. 2004..These results suggest that there may be negligible effects of HZE radiation on many behaviors during a 2-8-week period immediately after radiation...
High-LET radiation-induced response of microvessels in the HippocampusXiao Wen Mao
Departments of Radiation Medicine, Molecular Radiation Biology Laboratories, Loma Linda University, Loma Linda, California 92350, USA
Radiat Res 173:486-93. 2010..The correlation between radiation-induced alterations in the hippocampal microvessels and their functional consequences must be investigated in further studies...
Effects of lipopolysaccharide on 56Fe-particle radiation-induced impairment of synaptic plasticity in the mouse hippocampusRoman Vlkolinsky
Department of Radiation Medicine, Loma Linda University, Loma Linda, California 92354, USA
Radiat Res 168:462-70. 2007..Our results indicate that HZE-particle radiation alters normal electrophysiological properties of the CNS and the hippocampal response to LPS...
"Out-of-field" effects of head-localized proton irradiation on peripheral immune parametersMichael J Pecaut
Departments of Radiation Medicine, Radiobiology Program, Loma Linda University School of Medicine and Medical Center, Chan Shun Pavilion, Room A 1010, 11175 Campus Street, Loma Linda, CA 92354, USA
In Vivo 17:513-21. 2003..The data also suggest that immune modulation induced by localized proton, as well as other forms of radiation, should be taken into consideration when evaluating adjunctive immunotherapies in patients receiving radiotherapy...
Effects of protons and HZE particles on glutamate transport in astrocytes, neurons and mixed culturesMartha C Sanchez
Molecular Radiation Biology Laboratories, Department of Radiation Medicine, Loma Linda University, Loma Linda, California 92350 1700, USA
Radiat Res 174:669-78. 2010..Uptake in mixed cultures after exposure to all three forms of radiation revealed a muted interactive response suggestive of the individual responses of each cellular phenotype acting in opposition...
Cytoskeletal and functional changes in bioreactor assembled thyroid tissue organoids exposed to gamma radiationLora M Green
Radiobiology Program, Loma Linda University Chan Shun Pavilion, Rm A1010, 11175 Campus Street, Loma Linda, CA 92354, USA
J Radiat Res 43:S213-8. 2002..Thus, the engineered tissue responses to radiation differed from those of conventional tissue culture making it a potentially better mimic of the in vivo situation...
Dose and dose rate effects of whole-body proton irradiation on leukocyte populations and lymphoid organs: part IDaila S Gridley
Department of Radiation Medicine, Radiobiology Program, Loma Linda University School of Medicine and Medical Center, Chan Shun Pavilion, Room A 1010, 11175 Campus Street, Loma Linda, CA 92354, USA
Immunol Lett 80:55-66. 2002..Results from gamma- and proton-irradiated groups (both at 3 Gy HDR) were similar, although proton-irradiation gave consistently lower values in some measurements...
