D L Bellinger
Affiliation: Loma Linda University
- Changes in the density and distribution of sympathetic nerves in spleens from Lewis rats with adjuvant-induced arthritis suggest that an injury and sprouting response occursDianne Lorton
Hoover Arthritis Research Center, Sun Health Research Institute, Sun City, Arizona 85351, USA
J Comp Neurol 489:260-73. 2005..The redistribution of NA nerves into the red pulp may be critical in modulating immune functions that contribute to the chronic inflammatory stages of arthritis...
- Effects of interleukin-2 on the expression of corticotropin-releasing hormone in nerves and lymphoid cells in secondary lymphoid organs from the Fischer 344 ratD L Bellinger
Center for Neuroimmunology, Department of Neurobiology and Anatomy, Loma Linda University School of Medicine, Box 603, 11021 Campus Street, Loma Linda, CA 92352, USA
J Neuroimmunol 119:37-50. 2001..These findings indicate that IL-2 stimulates the synthesis of CRH in nerves that innervate the F344 rat spleen, and promote the appearance of CRH(+) immunocytes into draining mesenteric lymph nodes...
- Strain differences in the expression of corticotropin-releasing hormone immunoreactivity in nerves that supply the spleen and thymusD L Bellinger
Center for Neuroimmunology, Loma Linda University School of Medicine, Loma Linda, Calif, USA
Neuroimmunomodulation 9:78-87. 2001..These findings indicate strain differences in neurotransmitter-specific nerves that innervate the rat spleen and thymus under basal conditions...
- Aging and sympathetic modulation of immune function in Fischer 344 rats: effects of chemical sympathectomy on primary antibody responseDenise L Bellinger
Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, 11021 Campus Street, AH 325, Loma Linda, CA 92350, United States
J Neuroimmunol 165:21-32. 2005..Thus, the SNS can inhibit antibody produced in response to a protein antigen in both young and old F344 rats...
- Sympathetic innervation of the spleen in male Brown Norway rats: a longitudinal aging studySam D Perez
Department of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA 92350, USA
Brain Res 1302:106-17. 2009..Given the unique T-helper-2 bias in BN rats, altered sympathetic-immune communication may be important for understanding the age-related rise in asthma and autoimmunity...
- Sympathetic modulation of immunity: relevance to diseaseDenise L Bellinger
Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, 11021 Campus Street, Alumni Hall 325, Loma Linda, CA 92352, USA
Cell Immunol 252:27-56. 2008..However, a better understanding of neural-immune interactions is needed to develop strategies for treatment of immune-mediated diseases that are designed to return homeostasis and restore normal functioning neural-immune networks...
- Sympathetic nervous system and lymphocyte proliferation in the Fischer 344 rat spleen: a longitudinal studyDenise L Bellinger
Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, Loma Linda, CA 92350, USA
Neuroimmunomodulation 15:260-71. 2008..These studies suggested potential sympathetic nervous system involvement in age-induced immune dysregulation...
- Maternal and early life stress effects on immune function: relevance to immunotoxicologyDenise L Bellinger
Department of Human Anatomy and Pathology, Loma Linda University School of Medicine, Loma Linda, CA 92352, USA
J Immunotoxicol 5:419-44. 2008..Aging, exposure to teratogens, and psychological stress interact to increase vulnerability and put the elderly at the greatest risk for disease...
- The importance of timing of adrenergic drug delivery in relation to the induction and onset of adjuvant-induced arthritisCheri L Lubahn
Hoover Arthritis Research Center, Sun Health Research Institute, 10515 W Sante Fe Drive, Sun City, AZ 85351, USA
Brain Behav Immun 18:563-71. 2004..Given current drug therapies are not effective in preventing bone destruction, these data support using adrenergic drugs as bone sparing treatments in RA...
- Bidirectional communication between the brain and the immune system: implications for physiological sleep and disorders with disrupted sleepDianne Lorton
Hoover Arthritis Research Center, Sun Health Research Institute, Sun City, AZ 85372, USA
Neuroimmunomodulation 13:357-74. 2006..This article reviews our current understanding of neuroimmune interactions in normal sleep and sleep deprivation, and the influence of these interactions on selected disorders characterized by pathological sleep...
- Mechanisms of Psychosocial Influences on Prostate CancerDenise Bellinger; Fiscal Year: 2007....