Benjamin A Lipsky

Summary

Country: USA

Publications

  1. doi request reprint The value of a wound score for diabetic foot infections in predicting treatment outcome: a prospective analysis from the SIDESTEP trial
    Benjamin A Lipsky
    Primary Care Clinic, Antibiotic Research, VA Puget Sound Health Care System, University of Washington School of Medicine, 1660 South Columbian Way, Seattle, WA 98108, USA
    Wound Repair Regen 17:671-7. 2009
  2. ncbi request reprint Diagnosis and treatment of diabetic foot infections
    Benjamin A Lipsky
    Medical Service, Veterans Affairs Puget Sound Health Care System, and Division of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98108 9804, USA
    Clin Infect Dis 39:885-910. 2004
  3. ncbi request reprint Treating diabetic foot infections with sequential intravenous to oral moxifloxacin compared with piperacillin-tazobactam/amoxicillin-clavulanate
    Benjamin A Lipsky
    VA Puget Sound Health Care System and University of Washington, Seattle, WA, USA
    J Antimicrob Chemother 60:370-6. 2007
  4. ncbi request reprint Medical treatment of diabetic foot infections
    Benjamin A Lipsky
    Department of Medicine, University of Washington School of Medicine, and General Internal Medicine Clinic, VA Puget Sound Health Care System, Seattle 98108 1597, USA
    Clin Infect Dis 39:S104-14. 2004
  5. ncbi request reprint A report from the international consensus on diagnosing and treating the infected diabetic foot
    Benjamin A Lipsky
    Diabetes Metab Res Rev 20:S68-77. 2004
  6. ncbi request reprint Diagnosing and treating diabetic foot infections
    Benjamin A Lipsky
    University of Washington and VA Puget Sound Health Care System, Seattle, Washington, USA
    Diabetes Metab Res Rev 20:S56-64. 2004
  7. doi request reprint Topical versus systemic antimicrobial therapy for treating mildly infected diabetic foot ulcers: a randomized, controlled, double-blinded, multicenter trial of pexiganan cream
    Benjamin A Lipsky
    Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98116 1597, USA
    Clin Infect Dis 47:1537-45. 2008
  8. ncbi request reprint Treating foot infections in diabetic patients: a randomized, multicenter, open-label trial of linezolid versus ampicillin-sulbactam/amoxicillin-clavulanate
    Benjamin A Lipsky
    Antibiotic Research Clinic, Veterans Affairs Puget Sound Health Care System, and Department of Medicine, University of Washington, Seattle, Washington 98108 1597, USA
    Clin Infect Dis 38:17-24. 2004
  9. ncbi request reprint Ertapenem versus piperacillin/tazobactam for diabetic foot infections (SIDESTEP): prospective, randomised, controlled, double-blinded, multicentre trial
    Benjamin A Lipsky
    University of Washington School of Medicine and Veterans Affairs Puget Sound Health Care System S 111 GIMC, 1660 S Columbian Way, Seattle, WA 98108, USA
    Lancet 366:1695-703. 2005
  10. doi request reprint 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections
    Benjamin A Lipsky
    Department of Medicine, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
    Clin Infect Dis 54:e132-73. 2012

Detail Information

Publications64

  1. doi request reprint The value of a wound score for diabetic foot infections in predicting treatment outcome: a prospective analysis from the SIDESTEP trial
    Benjamin A Lipsky
    Primary Care Clinic, Antibiotic Research, VA Puget Sound Health Care System, University of Washington School of Medicine, 1660 South Columbian Way, Seattle, WA 98108, USA
    Wound Repair Regen 17:671-7. 2009
    ..This easily performed wound score appears to be a reliable, valid, and useful tool for predicting clinical outcomes. Further validation studies in different patient populations should refine the items included...
  2. ncbi request reprint Diagnosis and treatment of diabetic foot infections
    Benjamin A Lipsky
    Medical Service, Veterans Affairs Puget Sound Health Care System, and Division of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98108 9804, USA
    Clin Infect Dis 39:885-910. 2004
  3. ncbi request reprint Treating diabetic foot infections with sequential intravenous to oral moxifloxacin compared with piperacillin-tazobactam/amoxicillin-clavulanate
    Benjamin A Lipsky
    VA Puget Sound Health Care System and University of Washington, Seattle, WA, USA
    J Antimicrob Chemother 60:370-6. 2007
    ....
  4. ncbi request reprint Medical treatment of diabetic foot infections
    Benjamin A Lipsky
    Department of Medicine, University of Washington School of Medicine, and General Internal Medicine Clinic, VA Puget Sound Health Care System, Seattle 98108 1597, USA
    Clin Infect Dis 39:S104-14. 2004
    ..Definitive therapy depends on culture results and the clinical response. Bone infection is particularly difficult to treat and often requires surgery. Several adjuvant agents may be beneficial in some cases...
  5. ncbi request reprint A report from the international consensus on diagnosing and treating the infected diabetic foot
    Benjamin A Lipsky
    Diabetes Metab Res Rev 20:S68-77. 2004
    ..Among the factors predisposing diabetic patients to foot infections are ill-defined immunological perturbations 56; foot anatomy may foster proximal spread of infection and ischemic necrosis 78...
  6. ncbi request reprint Diagnosing and treating diabetic foot infections
    Benjamin A Lipsky
    University of Washington and VA Puget Sound Health Care System, Seattle, Washington, USA
    Diabetes Metab Res Rev 20:S56-64. 2004
    ..This paper presents a summary of a minisymposium on infection of the diabetic foot that was held at the fourth International Symposium on the Diabetic Foot, in Noordwijkerhout, The Netherlands...
  7. doi request reprint Topical versus systemic antimicrobial therapy for treating mildly infected diabetic foot ulcers: a randomized, controlled, double-blinded, multicenter trial of pexiganan cream
    Benjamin A Lipsky
    Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98116 1597, USA
    Clin Infect Dis 47:1537-45. 2008
    ....
  8. ncbi request reprint Treating foot infections in diabetic patients: a randomized, multicenter, open-label trial of linezolid versus ampicillin-sulbactam/amoxicillin-clavulanate
    Benjamin A Lipsky
    Antibiotic Research Clinic, Veterans Affairs Puget Sound Health Care System, and Department of Medicine, University of Washington, Seattle, Washington 98108 1597, USA
    Clin Infect Dis 38:17-24. 2004
    ..Linezolid was at least as effective as aminopenicillin/beta-lactamase inhibitors for treating foot infections in diabetic patients...
  9. ncbi request reprint Ertapenem versus piperacillin/tazobactam for diabetic foot infections (SIDESTEP): prospective, randomised, controlled, double-blinded, multicentre trial
    Benjamin A Lipsky
    University of Washington School of Medicine and Veterans Affairs Puget Sound Health Care System S 111 GIMC, 1660 S Columbian Way, Seattle, WA 98108, USA
    Lancet 366:1695-703. 2005
    ..Our aim was to assess the efficacy and safety of ertapenem versus piperacillin/tazobactam for foot infections...
  10. doi request reprint 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections
    Benjamin A Lipsky
    Department of Medicine, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
    Clin Infect Dis 54:e132-73. 2012
    ..Employing multidisciplinary foot teams improves outcomes. Clinicians and healthcare organizations should attempt to monitor, and thereby improve, their outcomes and processes in caring for DFIs...
  11. ncbi request reprint Clinical predictors of treatment failure for diabetic foot infections: data from a prospective trial
    Benjamin A Lipsky
    Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, WA 98108 1597, USA
    Int Wound J 4:30-8. 2007
    ..Increased white blood cell count and severe UT wound grade at baseline, but not other features, were significant independent and additive risk factors for clinical failure in patients treated for a diabetic foot infection...
  12. ncbi request reprint 2012 infectious diseases society of america clinical practice guideline for the diagnosis and treatment of diabetic foot infections
    Benjamin A Lipsky
    Department of Medicine, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle
    J Am Podiatr Med Assoc 103:2-7. 2013
    ..Employing multidisciplinary foot teams improves outcomes. Clinicians and healthcare organizations should attempt to monitor, and thereby improve, their outcomes and processes in caring for DFIs...
  13. doi request reprint Executive summary: 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections
    Benjamin A Lipsky
    Department of Medicine, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA
    Clin Infect Dis 54:1679-84. 2012
    ..Employing multidisciplinary foot teams improves outcomes. Clinicians and healthcare organizations should attempt to monitor, and thereby improve, their outcomes and processes in caring for DFIs...
  14. doi request reprint The role of diabetes mellitus in the treatment of skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus: results from three randomized controlled trials
    Benjamin A Lipsky
    Medical Service, VA Puget Sound Health Care System, 1880 S Columbian Way S 111 GIMC, Seattle, WA 98108 1587, USA
    Int J Infect Dis 15:e140-6. 2011
    ..To compare outcomes of treating complicated skin and skin structure infections (cSSSI) caused by methicillin-resistant Staphylococcus aureus (MRSA) with linezolid versus vancomycin in diabetic and non-diabetic patients...
  15. pmc Developing and validating a risk score for lower-extremity amputation in patients hospitalized for a diabetic foot infection
    Benjamin A Lipsky
    Department of Medicine, University of Washington, Seattle, WA, USA
    Diabetes Care 34:1695-700. 2011
    ..We sought to develop and validate a risk score to aid in the early identification of patients hospitalized for diabetic foot infection who are at highest risk of LEA...
  16. doi request reprint The evaluation and treatment of complicated skin and skin structure infections
    Paul B Cornia
    University of Washington School of Medicine, Primary and Specialty Medicine Service, Veterans Affairs Puget Sound Health Care System and Department of Medicine, Seattle, WA 98108 1597, USA
    Expert Opin Pharmacother 9:717-30. 2008
    ..Skin and skin structure infections are frequently encountered in clinical practice. Fortunately, these infections usually produce only mild to moderate symptoms and signs. Some, however, are severe and may even be life-threatening...
  17. ncbi request reprint Does this coughing adolescent or adult patient have pertussis?
    Paul B Cornia
    Primary and Specialty Medical Care Service, Veterans Affairs Puget Sound Health Care System, and Department of Medicine, University of Washington School of Medicine, Seattle, USA
    JAMA 304:890-6. 2010
    ..Pertussis is often overlooked as a cause of chronic cough, especially in adolescents and adults. Several symptoms are classically thought to be suggestive of pertussis, but the diagnostic value of each of them is uncertain...
  18. ncbi request reprint Topical application of a gentamicin-collagen sponge combined with systemic antibiotic therapy for the treatment of diabetic foot infections of moderate severity: a randomized, controlled, multicenter clinical trial
    Benjamin A Lipsky
    Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, WA, USA
    J Am Podiatr Med Assoc 102:223-32. 2012
    ....
  19. ncbi request reprint Risk factors for recurrence of diabetic foot ulcers: prospective follow-up analysis in the Eurodiale subgroup
    Michal Dubsky
    Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic Department of Internal Medicine, University Hospital Maastricht, Maastricht, The Netherlands General Medical Service, VA Puget Sound Health Care System, Department of Medicine, University of Washington, Seattle, WA, USA
    Int Wound J 10:555-61. 2013
    ....
  20. ncbi request reprint Optimising antimicrobial therapy in diabetic foot infections
    Nalini Rao
    Division of Infectious Disease, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232 1381, USA
    Drugs 67:195-214. 2007
    ..Certain other organisms, such as Pseudomonas aeruginosa and Enterococcus spp., while potentially pathogenic, are often colonisers that do not require targeted therapy...
  21. ncbi request reprint Clinical problem-solving. Red snapper or crab?
    Paul B Cornia
    Primary and Specialty Medical Care Service, Veterans Affairs Puget Sound Health Care System, Seattle 98108 1597, USA
    N Engl J Med 350:1443-8. 2004
  22. ncbi request reprint The microbiology of bacteriuria in men: a 5-year study at a Veterans' Affairs hospital
    Paul B Cornia
    Primary and Specialty Medicine Service, Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, WA 98108 1597, USA
    Diagn Microbiol Infect Dis 56:25-30. 2006
    ..1 for GNR). We conclude that the microorganisms causing bacteriuria in older male veterans are substantially different from those found in women, and the Gram-stained smear provides useful information on the causative organisms...
  23. ncbi request reprint Computer-based order entry decreases duration of indwelling urinary catheterization in hospitalized patients
    Paul B Cornia
    Primary and Specialty Medicine Service, Veterans Affairs Puget Sound Health Care System, and the Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
    Am J Med 114:404-7. 2003
  24. ncbi request reprint Skin, soft tissue, bone, and joint infections in hospitalized patients: epidemiology and microbiological, clinical, and economic outcomes
    Benjamin A Lipsky
    VA Puget Sound Health Care System, Seattle, Washington 98108, USA
    Infect Control Hosp Epidemiol 28:1290-8. 2007
    ..There are currently few published studies on the epidemiology and clinical and economic outcomes of these infections, whether acquired in the community or healthcare setting, in a large population...
  25. ncbi request reprint New developments in diagnosing and treating diabetic foot infections
    Benjamin A Lipsky
    University of Washington, USA
    Diabetes Metab Res Rev 24:S66-71. 2008
    ....
  26. doi request reprint Predicting bacteremia among patients hospitalized for skin and skin-structure infections: derivation and validation of a risk score
    Benjamin A Lipsky
    General Medical Service, Veterans Affairs Puget Sound Health Care System, Department of Medicine, University of Washington, Seattle, Washington 98108, USA
    Infect Control Hosp Epidemiol 31:828-37. 2010
    ..We used selected demographic and clinical characteristics easily assessable at initial evaluation to develop a model for the early identification of patients with SSSI who are at higher risk for bacteremia...
  27. ncbi request reprint Are granulocyte colony-stimulating factors beneficial in treating diabetic foot infections?: A meta-analysis
    Mario Cruciani
    University of Washington, School of Medicine, Director, General Internal Medicine Clinic, VA Puget Sound Health Care System S 111 GIMC, 1660 South Columbian Way, Seattle, WA 98108 1597, USA
    Diabetes Care 28:454-60. 2005
    ..To assess the value of granulocyte colony-stimulating factor (G-CSF) as adjunctive therapy for diabetic foot infections...
  28. doi request reprint Commentary: indwelling urinary catheters in hospitalized patients: when in doubt, pull it out
    Paul B Cornia
    Primary and Specialty Medicine Service, Veterans Affairs Puget Sound Health Care System and the University of Washington School of Medicine, Seattle, Washington, USA
    Infect Control Hosp Epidemiol 29:820-2. 2008
  29. ncbi request reprint Treatment of bacterial prostatitis
    Benjamin A Lipsky
    General Internal Medicine Service, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA
    Clin Infect Dis 50:1641-52. 2010
    ..We review recent pharmacological and clinical data on treating bacterial prostatitis...
  30. ncbi request reprint Topical antimicrobial therapy for treating chronic wounds
    Benjamin A Lipsky
    Veterans Affairs Puget Sound Health Care System and 2University of Washington, School of Medicine, Seattle, WA 98108, USA
    Clin Infect Dis 49:1541-9. 2009
    ..We provide clinically relevant information on currently available topical antimicrobial agents...
  31. ncbi request reprint Which antimicrobial impregnated central venous catheter should we use? Modeling the costs and outcomes of antimicrobial catheter use
    Kristin D Marciante
    Pharmaceutical Outcomes Research and Policy Program, Department of Pharmacy, University of Washington, Seattle WA 98195, USA
    Am J Infect Control 31:1-8. 2003
    ..It remains unclear whether minocycline/rifampin catheters are cost-effective for all high-risk patients or only those requiring longer-term catheterization...
  32. pmc A prospective, multicenter, observational study of complicated skin and soft tissue infections in hospitalized patients: clinical characteristics, medical treatment, and outcomes
    Benjamin A Lipsky
    VA Puget Sound Health Care System and University of Washington, Seattle, WA, USA
    BMC Infect Dis 12:227. 2012
    ..We designed this prospective, multicenter, observational study to to explore the current epidemiology, treatment, and resulting clinical outcomes of cSSTIs to help develop strategies to potentially improve outcomes...
  33. ncbi request reprint Clinical problem-solving. Nothing to cough at--a 73-year-old man presented to the emergency department with a 4-day history of nonproductive cough that worsened at night
    Paul B Cornia
    Primary and Specialty Medical Care Service, Veterans Affairs Puget Sound Health Care System, and the Department of Medicine, University of Washington School of Medicine, Seattle, WA 98108 1597, USA
    N Engl J Med 357:1432-7. 2007
  34. pmc Influenza vaccination rates of children in households with high-risk adults
    Ru Chien Chi
    Veterans Administration Puget Sound Health Care System, Seattle, WA, USA
    Public Health Rep 125:192-8. 2010
    ..We evaluated influenza vaccine coverage among children to determine whether or not living with a high-risk adult predicts the likelihood of being vaccinated...
  35. ncbi request reprint Daptomycin for treating infected diabetic foot ulcers: evidence from a randomized, controlled trial comparing daptomycin with vancomycin or semi-synthetic penicillins for complicated skin and skin-structure infections
    Benjamin A Lipsky
    University of Washington School of Medicine, and General Internal Medicine Clinic, VA Puget Sound Health Care System S 111 GIMC, 1660 S Columbian Way, Seattle, WA 98108 1597, USA
    J Antimicrob Chemother 55:240-5. 2005
    ....
  36. ncbi request reprint Preventing foot ulcers in patients with diabetes
    Nalini Singh
    Department of Medicine, Division of Endocrinology, Veterans Affairs Puget Sound Healthcare System and University of Washington School of Medicine, Seattle 98108, USA
    JAMA 293:217-28. 2005
    ..0% to 4.1%, and the lifetime incidence may be as high as 25%. These ulcers frequently become infected, cause great morbidity, engender considerable financial costs, and are the usual first step to lower extremity amputation...
  37. ncbi request reprint Vascular catheter site care: the clinical and economic benefits of chlorhexidine gluconate compared with povidone iodine
    Nathorn Chaiyakunapruk
    Pharmaceutical Outcomes Research and Policy Program, Department of Pharmacy, University of Washington, Seattle, WA 98195 7630, USA
    Clin Infect Dis 37:764-71. 2003
    ..Use of chlorhexidine gluconate in place of the current standard solution for vascular catheter site care is a simple and cost-effective method of improving patient safety in the hospital setting...
  38. ncbi request reprint Superior pulmonary sulcus tumor with Pancoast syndrome
    Kier V Huehnergarth
    General Internal Medicine Clinic, University of Washington, Seattle, USA
    Mayo Clin Proc 79:1268. 2004
  39. ncbi request reprint "Are we there yet?"
    LISA H WILLIAMS
    Primary and Specialty Medicine Service, Veterans Affairs Puget Sound Health Care System, Department of Medicine, and the University of Washington School of Medicine, Seattle, Washington 98108, USA
    J Hosp Med 2:181-8. 2007
  40. ncbi request reprint Using maximal sterile barriers to prevent central venous catheter-related infection: a systematic evidence-based review
    Kent K Hu
    Northwest Health Services Research and Development Program, Department of Medicine, University of Washington and VA Puget Sound HCS, 1660 South Columbian Way, HSR and D 152, Seattle, WA 98108, USA
    Am J Infect Control 32:142-6. 2004
    ..Accordingly, we conducted a systematic, evidence-based review of the medical literature to determine the value of maximal sterile barriers...
  41. ncbi request reprint Use of maximal sterile barriers during central venous catheter insertion: clinical and economic outcomes
    Kent K Hu
    Northwest Health Services Research and Development Program, Veterans Affairs Puget Sound Health Care System, University of Washington, Seattle 98108, USA
    Clin Infect Dis 39:1441-5. 2004
    ..Use of MSBs when placing CVCs may reduce the risk of infections but is more cumbersome, time-consuming, and expensive than other techniques...
  42. ncbi request reprint Comparative costs of ertapenem and piperacillin-tazobactam in the treatment of diabetic foot infections
    Alan D Tice
    John A Burns School of Medicine, University of Hawaii, Honolulu, USA
    Am J Health Syst Pharm 64:1080-6. 2007
    ..To evaluate potential cost savings, trial data were used to determine the clinical outcomes for i.v. ertapenem given once daily and i.v. piperacillin-tazobactam given every six hours daily in treating diabetic foot infections...
  43. ncbi request reprint Risk factors for nosocomial urinary tract-related bacteremia: a case-control study
    Sanjay Saint
    Center for Practice Management and Outcomes Research, Ann Arbor VA Health Services Research and Development Center of Excellence, Ann Arbor, MI, USA
    Am J Infect Control 34:401-7. 2006
    ..Risk factors for bacteremia in patients with hospital-acquired bacteriuria are largely unknown. Given the morbidity and costs associated with nosocomial bacteremia, determining risk factors could enhance the safety of hospitalized patients...
  44. pmc Bacteriology of moderate-to-severe diabetic foot infections and in vitro activity of antimicrobial agents
    Diane M Citron
    R M Alden Research Laboratory, 2001 Santa Monica Blvd, Suite 685W, Santa Monica CA 90404, USA
    J Clin Microbiol 45:2819-28. 2007
    ..Moderate-to-severe DFIs are typically polymicrobial, and almost half include anaerobes. Our antibiotic susceptibility results can help to inform therapeutic choices...
  45. ncbi request reprint Managing skin and soft tissue infections: expert panel recommendations on key decision points
    Lawrence J Eron
    University of Hawaii, John A Burns Medical School, Honolulu, HI, USA
    J Antimicrob Chemother 52:i3-17. 2003
  46. ncbi request reprint What is the shelf life of physician-mixed antibiotic-impregnated calcium sulfate pellets?
    David G Armstrong
    Department of Surgery, Southern Arizona Veterans Affairs Health Care System, Tucson, AZ 85723, USA
    J Foot Ankle Surg 42:302-4. 2003
    ....
  47. ncbi request reprint Condom versus indwelling urinary catheters: a randomized trial
    Sanjay Saint
    Center for Practice Management and Outcomes Research, Ann Arbor Department of Veterans Affairs Health Services Research and Development Center of Excellence, Ann Arbor, Michigan, USA
    J Am Geriatr Soc 54:1055-61. 2006
    ..To compare condom and indwelling urinary catheters in terms of infection risk and patient satisfaction...
  48. ncbi request reprint Diabetic foot infections: stepwise medical and surgical management
    David G Armstrong
    Dr William M Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, Chicago IL, USA
    Int Wound J 1:123-32. 2004
    ..Most foot ulcers occur on the plantar surface of the foot, thus requiring a plantar incision for any drainage procedure...
  49. ncbi request reprint Indwelling urinary catheters: a one-point restraint?
    Sanjay Saint
    Ann Intern Med 137:125-7. 2002
  50. ncbi request reprint Treatment for diabetic foot ulcers
    Peter R Cavanagh
    Diabetic Foot Care Program, Department of Biomedical Engineering, and the Orthopaedic Research Center, Cleveland Clinic Foundation, Cleveland 44195, OH, USA
    Lancet 366:1725-35. 2005
    ..Ulcer recurrence rates are high, but appropriate education for patients, the provision of posthealing footwear, and regular foot care can reduce rates of re-ulceration...
  51. ncbi request reprint Does dermal thermometry predict clinical outcome in diabetic foot infection? Analysis of data from the SIDESTEP* trial
    David G Armstrong
    Rosalind Franklin University, Chicago, IL, USA
    Int Wound J 3:302-7. 2006
    ..While there was no overall relationship between skin temperature and poor clinical outcome, there may be a threshold effect in DT (<10 degrees F versus >10 degrees F) between the limbs at baseline that predicts outcome of therapy...
  52. doi request reprint Bone of contention: diagnosing diabetic foot osteomyelitis
    Benjamin A Lipsky
    Clin Infect Dis 47:528-30. 2008
  53. ncbi request reprint Advances in the treatment of diabetic foot infections
    David G Armstrong
    Podiatry Section, Department of Surgery, Southern Arizona Veterans Affairs Medical Center, and University of Arizona, Tucson, Arizona 85750, USA
    Diabetes Technol Ther 6:167-77. 2004
    ..g., antibiotic beads, impregnated sponges) and novel antibiotics (e.g., levofloxacin, linezolid) are providing possible solutions to the challenges posed by this physically, emotionally, and financially devastating condition...
  54. ncbi request reprint Complicated infections of skin and skin structures: when the infection is more than skin deep
    Mark J DiNubile
    Merck Research Laboratories, BL 3 4, PO Box 4, West Point, PA 19486, USA
    J Antimicrob Chemother 53:ii37-50. 2004
    ..Surgical debridement is important for many complicated infections, and is the critical element in managing necrotizing fasciitis and myonecrosis...
  55. ncbi request reprint Probe-to-bone test for diagnosing diabetic foot osteomyelitis: reliable or relic?
    Lawrence A Lavery
    Department of Surgery, Scott and White Hospital, 703 Highland Spring Lane, Georgetown, TX 78628, USA
    Diabetes Care 30:270-4. 2007
    ..We sought to assess the accuracy of the probe-to-bone (PTB) test in diagnosing foot osteomyelitis in a cohort of diabetic patients with bone culture proven disease...
  56. ncbi request reprint Diabetic foot infections: microbiology made modern? Array of hope
    Benjamin A Lipsky
    Diabetes Care 30:2171-2. 2007
  57. ncbi request reprint Clinical management of diabetic foot infection: diagnostics, therapeutics and the future
    Philippa C Matthews
    Bone Infection Unit, Nuffield Orthopaedic Centre NHS Trust, Windmill Road, Headington, Oxford OX3 7LD, UK
    Expert Rev Anti Infect Ther 5:117-27. 2007
    ..We discuss this complex group of infections with a particular emphasis on medical management of osteomyelitis, while also highlighting the importance of a broad multidisciplinary approach to eradicating infection...
  58. ncbi request reprint Chlorhexidine compared with povidone-iodine solution for vascular catheter-site care: a meta-analysis
    Nathorn Chaiyakunapruk
    Department of Pharmacy Practice, School of Pharmacy, Naresuan University, Pitsanuloak 65000, Thailand
    Ann Intern Med 136:792-801. 2002
    ..This study evaluated the efficacy of skin disinfection with chlorhexidine gluconate compared with povidone-iodine solution in preventing catheter-related bloodstream infection...
  59. ncbi request reprint Validation of the Infectious Diseases Society of America's diabetic foot infection classification system
    Lawrence A Lavery
    Department of Surgery, Scott and White Hospital, Texas A and M University Health Science Center College of Medicine, Temple, Texas, USA
    Clin Infect Dis 44:562-5. 2007
    ..6; P<.001) with increasing infection severity. The Infectious Diseases Society of America's foot infection classification system may be a useful tool for grading foot infections...
  60. ncbi request reprint Risk factors for foot infections in individuals with diabetes
    Lawrence A Lavery
    Department of Surgery, Scott and White Hospital, Texas A and M University Health Science Center College of Medicine, Temple, TX, USA
    Diabetes Care 29:1288-93. 2006
    ..To prospectively determine risk factors for foot infection in a cohort of people with diabetes...
  61. doi request reprint Nothing to cough at
    Perrianne Lurie
    N Engl J Med 358:857; author reply 857. 2008
  62. ncbi request reprint Controversies in diagnosing and managing osteomyelitis of the foot in diabetes
    William J Jeffcoate
    Department of Diabetes and Endocrinology, City Hospital, Nottingham, United Kingdom
    Clin Infect Dis 39:S115-22. 2004
    ..We review the microbiology of osteomyelitis of the foot in diabetes, the benefits and limitations of various diagnostic procedures, and the evidence for the effectiveness of both surgical and nonsurgical approaches to management...
  63. ncbi request reprint The Biogun: a novel way of eradicating methicillin-resistant Staphylococcus aureus colonization in diabetic foot ulcers. Response to Dang et al
    Benjamin A Lipsky
    Diabetes Care 29:2181; author reply 2181-2. 2006
  64. ncbi request reprint Antibiotic treatment of osteomyelitis: what have we learned from 30 years of clinical trials?
    Luca Lazzarini
    Department of Infectious Diseases and Tropical Medicine, S Bortolo Hospital, 36100 Vicenza, Italy
    Int J Infect Dis 9:127-38. 2005
    ..To determine the most appropriate approach to antibiotic therapy for osteomyelitis, the medical literature for articles published from 1968 to 2000 was reviewed...