Katerina V Savelieva

Summary

Affiliation: Lexicon Pharmaceuticals
Country: USA

Publications

  1. pmc Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants
    Katerina V Savelieva
    Lexicon Pharmaceuticals Incorporated, The Woodlands, TX, USA
    PLoS ONE 3:e3301. 2008
  2. doi request reprint Differential sensitivity to SSRI and tricyclic antidepressants in juvenile and adult mice of three strains
    Sara S Mason
    Department of Neuroscience, Lexicon Pharmaceuticals, Inc, The Woodlands, TX 77381, USA
    Eur J Pharmacol 602:306-15. 2009
  3. pmc Characterization of PTPRG in knockdown and phosphatase-inactive mutant mice and substrate trapping analysis of PTPRG in mammalian cells
    Wandong Zhang
    Neuroscience Research, Lexicon Pharmaceuticals, Inc, The Woodlands, TX, USA
    PLoS ONE 7:e45500. 2012
  4. doi request reprint Learning and memory impairment in Eph receptor A6 knockout mice
    Katerina V Savelieva
    Neuroscience Research, Lexicon Pharmaceuticals Incorporated, 8800 Technology Forest Place, The Woodlands, TX 77381 1160, USA
    Neurosci Lett 438:205-9. 2008
  5. pmc Loss of the putative catalytic domain of HDAC4 leads to reduced thermal nociception and seizures while allowing normal bone development
    Indrani Rajan
    Neuroscience Research, Lexicon Pharmaceuticals Inc, The Woodlands, TX, USA
    PLoS ONE 4:e6612. 2009
  6. ncbi request reprint Use of a platform in an automated open-field to enhance assessment of anxiety-like behaviors in mice
    Vladimir M Pogorelov
    Lexicon Genetics Inc, Department of Neuroscience, 8800 Technology Forest Place, The Woodlands, TX 77381, USA
    J Neurosci Methods 162:222-8. 2007

Collaborators

Detail Information

Publications6

  1. pmc Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants
    Katerina V Savelieva
    Lexicon Pharmaceuticals Incorporated, The Woodlands, TX, USA
    PLoS ONE 3:e3301. 2008
    ..The behavioral effects observed in the TPH2 KO and DKO mice strongly confirm the role of 5-HT and its synthetic enzymes in the etiology and treatment of affective disorders...
  2. doi request reprint Differential sensitivity to SSRI and tricyclic antidepressants in juvenile and adult mice of three strains
    Sara S Mason
    Department of Neuroscience, Lexicon Pharmaceuticals, Inc, The Woodlands, TX 77381, USA
    Eur J Pharmacol 602:306-15. 2009
    ..Further examination of these effects is needed to determine whether it may be related to age-dependent difference in the clinical response to antidepressants of these classes...
  3. pmc Characterization of PTPRG in knockdown and phosphatase-inactive mutant mice and substrate trapping analysis of PTPRG in mammalian cells
    Wandong Zhang
    Neuroscience Research, Lexicon Pharmaceuticals, Inc, The Woodlands, TX, USA
    PLoS ONE 7:e45500. 2012
    ..Additional investigation of RPTPĪ³ activity and regulation may lead to a better understanding of the biochemical underpinnings of human depression...
  4. doi request reprint Learning and memory impairment in Eph receptor A6 knockout mice
    Katerina V Savelieva
    Neuroscience Research, Lexicon Pharmaceuticals Incorporated, 8800 Technology Forest Place, The Woodlands, TX 77381 1160, USA
    Neurosci Lett 438:205-9. 2008
    ..These findings suggest that EphA6, in line with a number of other Eph receptors and their ephrin ligands, is involved in neural circuits underlying aspects of learning and memory...
  5. pmc Loss of the putative catalytic domain of HDAC4 leads to reduced thermal nociception and seizures while allowing normal bone development
    Indrani Rajan
    Neuroscience Research, Lexicon Pharmaceuticals Inc, The Woodlands, TX, USA
    PLoS ONE 4:e6612. 2009
    ..As the mutant mice aged past 5 months, convulsions appeared, often elicited by handling. Our findings confirm the sufficiency of the N-terminal domain for muscle and bone development, while revealing other roles of HDAC4...
  6. ncbi request reprint Use of a platform in an automated open-field to enhance assessment of anxiety-like behaviors in mice
    Vladimir M Pogorelov
    Lexicon Genetics Inc, Department of Neuroscience, 8800 Technology Forest Place, The Woodlands, TX 77381, USA
    J Neurosci Methods 162:222-8. 2007
    ....