Research Topics
Genomes and GenesSpecies | R ReadSummaryAffiliation: Lexicon Pharmaceuticals Country: USA Publications
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Detail Information
Publications
Situs inversus in Dpcd/Poll-/-, Nme7-/- , and Pkd1l1-/- miceP Vogel
Pathology Department, Lexicon Pharmaceuticals Inc, 8800 Technology Forest Place, The Woodlands, TX 77381, USA
Vet Pathol 47:120-31. 2010..However, the heart and great vessels of Pkd1l1(-/-) mice were not examined, and it is possible that the decreased viability of Pkd1l1(-/-) mice is due to undiagnosed cardiovascular defects associated with heterotaxy...
Ectonucleoside triphosphate diphosphohydrolase type 5 (Entpd5)-deficient mice develop progressive hepatopathy, hepatocellular tumors, and spermatogenic arrestR Read
Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, TX 77381, USA
Vet Pathol 46:491-504. 2009..This mouse model could contribute to the understanding of the influence of ENTPD5/PCPH on cellular proliferation and neoplasia...
Histopathological and neurological features of Atg4b knockout miceR Read
Department of Pathology, Lexicon Pharmaceuticals, The Woodlands, TX 77381, USA
Vet Pathol 48:486-94. 2011..These findings appear to be different than those reported for inactivation of other Atg4 homologs, suggesting that these homologs have tissue-specific functions beyond redundancy...
Tubulin tyrosine ligase-like 1 deficiency results in chronic rhinosinusitis and abnormal development of spermatid flagella in miceP Vogel
Lexicon Pharmaceuticals, Pathology Department, 8800 Technology Forest Place, The Woodlands, TX 77381 1160, USA
Vet Pathol 47:703-12. 2010....
Pathology of congenital generalized lipodystrophy in Agpat2-/- miceP Vogel
Lexicon Pharmaceuticals, Inc, Pathology Department, The Woodlands, TX 77381 1160, USA
Vet Pathol 48:642-54. 2011....
Comparative pathology of murine mucolipidosis types II and IIICP Vogel
Lexicon Pharmaceuticals, Pathology Department, 8800 Technology Forest Place, The Woodlands, TX 77381 1160, USA
Vet Pathol 46:313-24. 2009..We conclude that mice lacking either alpha/beta or gamma subunits displayed clinical and pathologic features that differed substantially from those reported in humans having mutations in orthologous genes...
An alternative splicing variant in Clcn7-/- mice prevents osteopetrosis but not neural and retinal degenerationI Rajan
Lexicon Pharmaceuticals, Pathology Department, The Woodlands, TX 77381 1160, USA
Vet Pathol 48:663-75. 2011....
