Genomes and Genes
Affiliation: Lexicon Pharmaceuticals
- The adaptor protein Sh2d3c is critical for marginal zone B cell development and functionAmin Al-Shami
Lexicon Pharmaceuticals, The Woodlands, TX 77381, USA
J Immunol 185:327-34. 2010....
- Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse developmentAmin Al-Shami
Lexicon Pharmaceuticals, Inc, The Woodlands, Texas, United States of America
PLoS ONE 5:e13654. 2010..In conclusion, this is the first report characterizing the physiological roles of Uch37 and Rpn13 in murine development and implicating a non-ATPase proteasomal protein, Rpn13, in the process of gametogenesis...
- Integrin-α FG-GAP repeat-containing protein 2 is critical for normal B cell differentiation and controls disease development in a lupus modelAmin Al-Shami
Lexicon Pharmaceuticals, Inc, The Woodlands, TX 77381
J Immunol 191:3789-98. 2013..These results identify Itfg2 as a novel contributor to B cell differentiation and a negative regulator of the autoimmune response during lupus. ..