Amin Al-Shami

Summary

Affiliation: Lexicon Pharmaceuticals
Country: USA

Publications

  1. ncbi The adaptor protein Sh2d3c is critical for marginal zone B cell development and function
    Amin Al-Shami
    Lexicon Pharmaceuticals, The Woodlands, TX 77381, USA
    J Immunol 185:327-34. 2010
  2. pmc Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development
    Amin Al-Shami
    Lexicon Pharmaceuticals, Inc, The Woodlands, Texas, United States of America
    PLoS ONE 5:e13654. 2010
  3. doi Integrin-α FG-GAP repeat-containing protein 2 is critical for normal B cell differentiation and controls disease development in a lupus model
    Amin Al-Shami
    Lexicon Pharmaceuticals, Inc, The Woodlands, TX 77381
    J Immunol 191:3789-98. 2013
  4. ncbi Genetic deletion of Mst1 alters T cell function and protects against autoimmunity
    Konstantin V Salojin
    Lexicon Pharmaceuticals, Inc, The Woodlands, Texas, United States of America
    PLoS ONE 9:e98151. 2014

Detail Information

Publications4

  1. ncbi The adaptor protein Sh2d3c is critical for marginal zone B cell development and function
    Amin Al-Shami
    Lexicon Pharmaceuticals, The Woodlands, TX 77381, USA
    J Immunol 185:327-34. 2010
    ....
  2. pmc Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development
    Amin Al-Shami
    Lexicon Pharmaceuticals, Inc, The Woodlands, Texas, United States of America
    PLoS ONE 5:e13654. 2010
    ..In conclusion, this is the first report characterizing the physiological roles of Uch37 and Rpn13 in murine development and implicating a non-ATPase proteasomal protein, Rpn13, in the process of gametogenesis...
  3. doi Integrin-α FG-GAP repeat-containing protein 2 is critical for normal B cell differentiation and controls disease development in a lupus model
    Amin Al-Shami
    Lexicon Pharmaceuticals, Inc, The Woodlands, TX 77381
    J Immunol 191:3789-98. 2013
    ..These results identify Itfg2 as a novel contributor to B cell differentiation and a negative regulator of the autoimmune response during lupus. ..
  4. ncbi Genetic deletion of Mst1 alters T cell function and protects against autoimmunity
    Konstantin V Salojin
    Lexicon Pharmaceuticals, Inc, The Woodlands, Texas, United States of America
    PLoS ONE 9:e98151. 2014
    ..In conclusion, this report implicates Mst1 as a critical regulator of adaptive immune responses, Th1/Th2-dependent cytokine production, and as a potential therapeutic target for immune disorders. ..