Research Topics
Species | Greg J HermannSummaryAffiliation: Lewis and Clark College Country: USA Publications
| Collaborators
|
Detail Information
Publications
Genetic analysis of lysosomal trafficking in Caenorhabditis elegansGreg J Hermann
Department of Biology, Lewis and Clark College, Portland, OR 97219, USA
Mol Biol Cell 16:3273-88. 2005..The glo mutants thus provide a simple model system for the analysis of lysosome-related organelle biogenesis in animal cells...
C. elegans BLOC-1 functions in trafficking to lysosome-related gut granulesGreg J Hermann
Department of Biology, Lewis and Clark College, Portland, Oregon, USA
PLoS ONE 7:e43043. 2012..Our work opens up the opportunity to address the function of this poorly understood complex in cell and organismal physiology using the genetic approaches available in C. elegans...
glo-3, a novel Caenorhabditis elegans gene, is required for lysosome-related organelle biogenesisBeverley M Rabbitts
Department of Biology, Lewis and Clark College, Portland, Oregon 97219, USA
Genetics 180:857-71. 2008..Our studies identify GLO-3 as a novel player in the formation of lysosome-related organelles...
Role of the Caenorhabditis elegans multidrug resistance gene, mrp-4, in gut granule differentiationErin Currie
Department of Biology, Lewis and Clark College, Portland, Oregon 97219, USA
Genetics 177:1569-82. 2007..In a search for genes that function similarly to mrp-4(+), we identified WHT-2, another ABC transporter that acts in parallel to MRP-4 for the formation of birefringent material in the gut granule...
Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelleLena K Schroeder
Department of Biology, Lewis and Clark College, Portland, OR 97219, USA
Mol Biol Cell 18:995-1008. 2007..Our results provide an explanation for the loss of Nile Red-stained fat in pgp-2(-) animals as well as insight into the specialized function of this lysosome-related organelle...
A Caenorhabditis elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps-1 functionSteven Levitte
Department of Biology, Lewis and Clark College, Portland, OR, USA
FEBS J 277:1420-39. 2010..WHT-2 possibly facilitates the increase in gut granule size of the umps-1(-) mutant by transporting orotic acid into the gut granule and promoting osmotically induced swelling of the compartment...
Characterization of a conserved apoptotic marker expressed in Caenorhabditis elegans phagocytic cellsRobin J Eisenhut
Department of Biology, Lewis and Clark College, Portland, OR 97219, USA
Biochem Biophys Res Commun 335:1231-8. 2005..This observation suggests that F2-P3E3 might recognize an epitope expressed in multiple cells in response to signals from a single corpse. F2-P3E3 represents a new tool for studying cell death in C. elegans...
