Research Topics
Species | Christina C LewisSummaryCountry: USA Publications
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Publications
Disease-specific gene expression profiling in multiple models of lung diseaseChristina C Lewis
Cincinnati Children s Hospital Medical Center Division of Immunobiology, 3333 Burnet Avenue, MLC 7038, Cincinnati, OH 45229, USA
Am J Respir Crit Care Med 177:376-87. 2008..However, analyses of individual diseases or models of diseases frequently yield extensive lists of differentially expressed genes with uncertain relationships to disease pathogenesis...
Differences in expression, affinity, and function of soluble (s)IL-4Ralpha and sIL-13Ralpha2 suggest opposite effects on allergic responsesMarat Khodoun
Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, USA
J Immunol 179:6429-38. 2007....
Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lungChristina C Lewis
Division of Immunobiology, Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio 45229, USA
J Allergy Clin Immunol 123:795-804.e8. 2009..Although these 2 cytokines share signaling components, the molecular mechanisms by which they mediate different phases of the allergic asthmatic response remain elusive...
Interleukin-4 and interleukin-13 augment the proliferative effect of dexamethasone on distal lung fibroblastsChristina C Lewis
National Jewish Medical and Research Center, Denver, CO 80206, USA
Chest 123:356S. 2003
Increased expression of platelet-derived growth factor receptor-beta in airway fibroblasts of severe asthmaticsChristina C Lewis
National Jewish Medical and Research Center, Denver, CO 80206, USA
Chest 123:428S-9S. 2003
Airway fibroblasts exhibit a synthetic phenotype in severe asthmaChristina C Lewis
Division of Pulmonary Sciences and Critical Care Medicine, National Jewish Medical and Research Center, Denver, Colo, USA
J Allergy Clin Immunol 115:534-40. 2005..Platelet-derived growth factor (PDGF) may have a significant role in airway remodeling in asthma, because it is a powerful inductor of many airway fibroblast activities such as collagen synthesis...
Dissecting asthma using focused transgenic modeling and functional genomicsDouglas A Kuperman
Department of Medicine, Allergy-Immunology Division, Northwestern University Feinberg School of Medicine, Chicago, USA
J Allergy Clin Immunol 116:305-11. 2005....
