Jeetain Mittal

Summary

Affiliation: Lehigh University
Country: USA

Publications

  1. pmc Dependence of protein folding stability and dynamics on the density and composition of macromolecular crowders
    Jeetain Mittal
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania, USA
    Biophys J 98:315-20. 2010
  2. pmc Tackling force-field bias in protein folding simulations: folding of Villin HP35 and Pin WW domains in explicit water
    Jeetain Mittal
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania, USA
    Biophys J 99:L26-8. 2010
  3. doi Structural ensemble of an intrinsically disordered polypeptide
    Jeetain Mittal
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States
    J Phys Chem B 117:118-24. 2013
  4. pmc Pair diffusion, hydrodynamic interactions, and available volume in dense fluids
    Jeetain Mittal
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, USA
    J Chem Phys 137:034110. 2012
  5. pmc Interfacial thermodynamics of confined water near molecularly rough surfaces
    Jeetain Mittal
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, USA
    Faraday Discuss 146:341-52; discussion 367-93, 395-401. 2010
  6. ncbi Does confining the hard-sphere fluid between hard walls change its average properties?
    Jeetain Mittal
    Department of Chemical Engineering, The University of Texas at Austin, Austin, Texas 78712, USA
    J Chem Phys 126:244708. 2007
  7. ncbi How short-range attractions impact the structural order, self-diffusivity, and viscosity of a fluid
    William P Krekelberg
    Department of Chemical Engineering, University of Texas at Austin, Austin, Texas 78712, USA
    J Chem Phys 127:044502. 2007
  8. ncbi Quantitative link between single-particle dynamics and static structure of supercooled liquids
    Jeetain Mittal
    Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA
    J Phys Chem B 110:18147-50. 2006
  9. ncbi Anomalous structure and dynamics of the Gaussian-core fluid
    William P Krekelberg
    Department of Chemical Engineering, University of Texas at Austin, Austin, Texas 78712, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 79:031203. 2009
  10. doi Modest protein-crowder attractive interactions can counteract enhancement of protein association by intermolecular excluded volume interactions
    Jonathan Rosen
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, USA
    J Phys Chem B 115:2683-9. 2011

Collaborators

Detail Information

Publications15

  1. pmc Dependence of protein folding stability and dynamics on the density and composition of macromolecular crowders
    Jeetain Mittal
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania, USA
    Biophys J 98:315-20. 2010
    ..A simple extension of the scaled-particle theory model, assuming additivity, can also describe the behavior of mixtures of crowding particles...
  2. pmc Tackling force-field bias in protein folding simulations: folding of Villin HP35 and Pin WW domains in explicit water
    Jeetain Mittal
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania, USA
    Biophys J 99:L26-8. 2010
    ..0 A RMSD of the experimental structures. This demonstrates that a simple backbone correction results in a more transferable force field, an important requirement if simulations are to be used to interpret folding mechanism...
  3. doi Structural ensemble of an intrinsically disordered polypeptide
    Jeetain Mittal
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States
    J Phys Chem B 117:118-24. 2013
    ..We show that p53 populates solution structures that strongly resemble the ligand (MDM2)-bound structure, but at the same time, the conformational free-energy landscape is relatively flat in the absence of the ligand...
  4. pmc Pair diffusion, hydrodynamic interactions, and available volume in dense fluids
    Jeetain Mittal
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, USA
    J Chem Phys 137:034110. 2012
    ..The procedure used here to determine the pair diffusion coefficients can also be used for single-particle diffusion in confinement with spherical symmetry...
  5. pmc Interfacial thermodynamics of confined water near molecularly rough surfaces
    Jeetain Mittal
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, USA
    Faraday Discuss 146:341-52; discussion 367-93, 395-401. 2010
    ..These microscopic changes in the density, hydrogen bonding, and water orientation contribute to the large increase in the interfacial free energy, and the change from a hydrophilic to a hydrophobic character of the surface...
  6. ncbi Does confining the hard-sphere fluid between hard walls change its average properties?
    Jeetain Mittal
    Department of Chemical Engineering, The University of Texas at Austin, Austin, Texas 78712, USA
    J Chem Phys 126:244708. 2007
    ..These paired thermodynamic/kinetic deviations from bulk behavior appear to reflect the geometric packing frustration that arises when the confined space cannot naturally accommodate an integer number of particle layers...
  7. ncbi How short-range attractions impact the structural order, self-diffusivity, and viscosity of a fluid
    William P Krekelberg
    Department of Chemical Engineering, University of Texas at Austin, Austin, Texas 78712, USA
    J Chem Phys 127:044502. 2007
    ..We discuss how these couplings reflect dynamic heterogeneities. Finally, we note that the simulation data suggest how repulsive and attractive glasses may generally be characterized by two distinct levels of short-range structural order...
  8. ncbi Quantitative link between single-particle dynamics and static structure of supercooled liquids
    Jeetain Mittal
    Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA
    J Phys Chem B 110:18147-50. 2006
    ..The generality of this observed structure-property relationship is supported by its ability to successfully describe the nontrivial behaviors of these very different types of model systems...
  9. ncbi Anomalous structure and dynamics of the Gaussian-core fluid
    William P Krekelberg
    Department of Chemical Engineering, University of Texas at Austin, Austin, Texas 78712, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 79:031203. 2009
    ..This finding, which deserves more comprehensive future study, appears to underscore the significance of higher-body correlations for the behavior of fluids with bounded interactions...
  10. doi Modest protein-crowder attractive interactions can counteract enhancement of protein association by intermolecular excluded volume interactions
    Jonathan Rosen
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, USA
    J Phys Chem B 115:2683-9. 2011
    ..We propose a simple theoretical model based on the scaled particle theory augmented by a mean-field attraction term that can explain our simulation results semiquantitatively...
  11. ncbi Thermodynamics predicts how confinement modifies the dynamics of the equilibrium hard-sphere fluid
    Jeetain Mittal
    Department of Chemical Engineering, The University of Texas at Austin, USA
    Phys Rev Lett 96:177804. 2006
    ..Thus, thermodynamics can be used to predict how confinement impacts dynamics...
  12. doi Structural characteristics of oligomeric DNA strands adsorbed onto single-walled carbon nanotubes
    Daniel Roxbury
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States
    J Phys Chem B 117:132-40. 2013
    ..Finally, we provide a summary of DNA structures observed for various DNA-SWCNT hybrids as a preliminary set of motifs that may be involved in the functional role of these hybrids...
  13. pmc Smoothing of the GB1 hairpin folding landscape by interfacial confinement
    Apratim Bhattacharya
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania, USA
    Biophys J 103:596-600. 2012
    ..These results from a simple confinement model may provide clues about the role of chaperonin confinement in smoothing folding landscapes by avoiding trapped intermediates...
  14. doi Binding between DNA and carbon nanotubes strongly depends upon sequence and chirality
    Akshaya Shankar
    Department of Chemical Engineering, and Bioengineering Program, Lehigh University, Bethlehem, Pennsylvania 18015, United States
    Langmuir 30:3176-83. 2014
    ..For the shorter sequences, the activation energy on the CNT varies periodically with the sequence. ..
  15. doi DNA base dimers are stabilized by hydrogen-bonding interactions including non-Watson-Crick pairing near graphite surfaces
    Akshaya Shankar
    Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, USA
    J Phys Chem B 116:12088-94. 2012
    ..This clearly highlights the importance of non-Watson-Crick base pairing in the development of secondary structures of oligonucleotides near surfaces...