Research Topics
| F A LederleSummaryCountry: USA Publications
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Publications
Smokers' relative risk for aortic aneurysm compared with other smoking-related diseases: a systematic reviewFrank A Lederle
Center for Chronic Disease Outcomes Research, Minneapolis VA Medical Center III 0, One Veterans Drive, Minneapolis, MN 55417, USA
J Vasc Surg 38:329-34. 2003..Study design: We conducted a systematic review of studies providing relative risk associated with smoking for both aortic aneurysm and other smoking-related diseases...
A summary of the contributions of the VA cooperative studies on abdominal aortic aneurysmsFrank A Lederle
University of Minnesota, Center for Epidemiological and Clinical Research, VA Medical Center, Minneapolis, MN 55417, USA
Ann N Y Acad Sci 1085:29-38. 2006..5 cm, and 25% within 6 months for AAA larger than 8.0 cm. The third, the Open Versus Endovascular Repair (OVER) Trial, is a multicenter randomized trial comparing long-term survival following two methods of elective AAA repair...
The prophylaxis of medical patients for thromboembolism pilot studyFrank A Lederle
Department of Medicine, Minneapolis Center for Epidemiological and Clinical Research, Veterans Affairs Medical Center, Minneapolis, Minn 55417, USA
Am J Med 119:54-9. 2006..We assessed the feasibility of a large randomized trial intended to determine whether low-dose heparin prophylaxis given throughout hospitalization reduces mortality and morbidity in general medical patients...
The natural history of abdominal aortic aneurysmF A Lederle
Center for Epidemiological and Clinical Research, VA Medical Center, Minneapolis 55417, USA
Acta Chir Belg 109:7-12. 2009..The search is on for drugs to favorably alter this natural history, and if successful, will doubtless shed much light on the pathophysiology of AAA enlargement...
Quality of life, impotence, and activity level in a randomized trial of immediate repair versus surveillance of small abdominal aortic aneurysmFrank A Lederle
Department of Medicine, Vetertans Affairs Medical Center III 0, Minneapolis, MN 55417, USA
J Vasc Surg 38:745-52. 2003....
Ultrasonographic screening for abdominal aortic aneurysmsFrank A Lederle
Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
Ann Intern Med 139:516-22. 2003..If elective repair is reserved for larger AAAs, one-time ultrasonographic screening for AAA can be recommended for men 65 to 79 years of age who have ever smoked [correction]...
Rupture rate of large abdominal aortic aneurysms in patients refusing or unfit for elective repairFrank A Lederle
Department of Medicine, Veterans Affairs Medical Center, Minneapolis, Minn 55417, USA
JAMA 287:2968-72. 2002....
Immediate repair compared with surveillance of small abdominal aortic aneurysmsFrank A Lederle
Veterans Affairs Medical Centers in Minneapolis, MN 55417, USA
N Engl J Med 346:1437-44. 2002..Whether elective surgical repair of small abdominal aortic aneurysms improves survival remains controversial...
Abdominal aortic aneurysm in womenF A Lederle
Department of Medicine, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
J Vasc Surg 34:122-6. 2001..The purpose of this study was to compare abdominal aortic aneurysm (AAA) associations in men and women...
Risk of rupture of large abdominal aortic aneurysms. Disagreement among vascular surgeonsF A Lederle
Department of Medicine, Minneapolis Veterans Affairs Medical Center, University of Minnesota, USA
Arch Intern Med 156:1007-9. 1996..The risk of rupture is usually estimated by a consulting vascular surgeon, but whether these estimates are well-supported or consistent has not previously been assessed...
Accuracy of teledermatology for pigmented neoplasmsErin M Warshaw
Minneapolis Veterans Affairs Medical Center, Center for Chronic Disease Outcomes Research, Minneapolis, Minnesota, USA
J Am Acad Dermatol 61:753-65. 2009..Accurate diagnosis and management of pigmented lesions is critical because of the morbidity and mortality associated with melanoma...
Cost-effectiveness of abdominal aortic aneurysm repair: a systematic reviewYvonne C Jonk
University of Minnesota, Minneapolis VA Center for Chronic Disease Outcomes Research, USA
Int J Technol Assess Health Care 23:205-15. 2007..Although open surgery has been considered the gold standard for prevention of AAA rupture, emerging less-invasive endovascular treatments have led to increased interest in evaluating the cost and cost-effectiveness of treatment options...
Abdominal aortic aneurysm events in the women's health initiative: cohort studyFrank A Lederle
VA Medical Center, Minneapolis, MN 55417, USA
BMJ 337:a1724. 2008..To assess the association between potential risk factors and subsequent clinically important abdominal aortic aneurysm events (repairs and ruptures) in women...
Endoscopic ultrasound and positron emission tomography for lung cancer stagingMandeep S Sawhney
Section of Gastroenterology, Minneapolis VA Medical Center, Minneapolis, Minnesota 55417, USA
Clin Gastroenterol Hepatol 4:846-51. 2006..We prospectively compared 2 promising new modalities, positron emission tomography (PET) and endoscopic ultrasound (EUS), for staging mediastinal lymph nodes...
Accuracy of teledermatology for nonpigmented neoplasmsErin M Warshaw
Minneapolis Veterans Affairs Medical Center, Center for Chronic Disease Outcomes Research, Minneapolis, Minnesota 55417, USA
J Am Acad Dermatol 60:579-88. 2009..Studies of teledermatology utilizing the standard reference of histopathology are lacking...
Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trialFrank A Lederle
Medicine Service, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
JAMA 302:1535-42. 2009..Limited data are available to assess whether endovascular repair of abdominal aortic aneurysm (AAA) improves short-term outcomes compared with traditional open repair...
Pulse versus continuous terbinafine for onychomycosis: a randomized, double-blind, controlled trialErin M Warshaw
Center for Chronic Disease Outcomes Research, Minneapolis, Minnesota, USA
J Am Acad Dermatol 53:578-84. 2005..Previous studies suggest that less costly, pulsed doses of antifungal medications may be as effective as standard, continuous doses. Terbinafine is the current treatment of choice for toenail onychomycosis...
A pilot evaluation of pulse itraconazole vs. terbinafine for treatment of Candida toenail onychomycosisErin M Warshaw
University of Minnesota, Minneapolis, MN, USA
Int J Dermatol 44:785-8. 2005
Are all commonly prescribed antipsychotics associated with greater mortality in elderly male veterans with dementia?Rebecca C Rossom
Department of Psychiatry, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
J Am Geriatr Soc 58:1027-34. 2010..To estimate mortality risk associated with individual commonly prescribed antipsychotics...
Impact of preoperative endoscopic ultrasound on non-small cell lung cancer stagingMandeep S Sawhney
Section of Gastroenterology, Minneapolis VA Medical Center, Minneapolis, MN, USA
Chest 132:916-21. 2007..To determine if the addition of preoperative endoscopic ultrasound (EUS) to non-small cell lung cancer staging can reduce the proportion of patients in whom malignant mediastinal lymph nodes (inoperable disease) are discovered at surgery...
The strange relationship between diabetes and abdominal aortic aneurysmF A Lederle
Department of Medicine III 0, Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
Eur J Vasc Endovasc Surg 43:254-6. 2012..Research focused on a protective effect of diabetes has already increased our understanding of the etiology of AAA, and might eventually pave the way for new therapies to slow AAA progression...
Should abdominal aortic aneurysm be managed differently in women?F A Lederle
Center for Epidemiological and Clinical Research, VA Medical Center, Minneapolis, MN 55417, USA
Scand J Surg 97:125-7. 2008..The totality of evidence available at present provides no good reason to alter for women the 5.5 cm threshold for elective repair established for men by the small AAA trials...
EUS-guided FNA for the diagnosis of advanced lung cancerMandeep S Sawhney
Section of Gastroenterology, Center for Epidemiological and Clinical Research, Minneapolis VA Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
Gastrointest Endosc 63:959-65. 2006..02). Two self-limited complications were noted during the study. CONCLUSIONS: EUS was an accurate and a safe method for obtaining a tissue diagnosis in patients with advanced incurable lung cancer...
The rational clinical examination. Does this patient have abdominal aortic aneurysm? F A Lederle
Department of Medicine, Minneapolis Veterans Affairs Medical Center, University of Minnesota, 55417, USA
JAMA 281:77-82. 1999....
Screening for AAA in the USAF A Lederle
Center for Epidemiological and Clinical Research, VA Medical Center, Minneapolis, MN 55417, USA
Scand J Surg 97:139-41. 2008..s...
Systematic review: repair of unruptured abdominal aortic aneurysmFrank A Lederle
Veterans Affairs Medical Center and University of Minnesota School of Public Health, Minneapolis, Minnesota 55417, USA
Ann Intern Med 146:735-41. 2007....
Should patients with anemia and low normal or normal serum ferritin undergo colonoscopy?Mandeep S Sawhney
Section of Gastroenterology, Minneapolis VA Medical Center, Minneapolis, Minnesota 55417, USA
Am J Gastroenterol 102:82-8. 2007..Patients with unexplained iron deficiency anemia have a greater prevalence of colonic neoplasia, and should be evaluated for a colonoscopy. The approach to patients with anemia without iron deficiency remains unclear...
Colorectal cancers found after a complete colonoscopyWilliam D Farrar
Section of Gastroenterology, Minneapolis VA Medical Center, Minneapolis, Minnesota, USA
Clin Gastroenterol Hepatol 4:1259-64. 2006..CONCLUSIONS: Incomplete polypectomy might play an important role in the development of interval colorectal cancer. No association between other colonoscopy-related factors or tumor characteristics and interval cancers was found...
Anticoagulant prophylaxis for hospitalized medical patientsFrank A Lederle
Ann Intern Med 147:523-4; author reply 524. 2007
Comment on "Screening for abdominal aortic aneurysm reduces overall mortality in men"Frank A Lederle
Eur J Vasc Endovasc Surg 36:620-1; author reply 621-2. 2008
Central intranodal blood vessel: a new EUS sign described in mediastinal lymph nodesMandeep S Sawhney
Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Gastrointest Endosc 65:602-8. 2007..The vascular architecture of normal lymph nodes is composed of prominent centrally located blood vessels. In malignant nodes, this pattern is distorted because of tumor infiltration and neovascularization...
Abdominal aortic aneurysm--open versus endovascular repairFrank A Lederle
N Engl J Med 351:1677-9. 2004
Endovascular repair of abdominal aortic aneurysm--round twoFrank A Lederle
N Engl J Med 352:2443-5. 2005
Screening for abdominal aortic aneurysm: a best-evidence systematic review for the U.S. Preventive Services Task ForceCraig Fleming
Oregon Evidence-based Practice Center and Center for Health Research, Kaiser Permanente, Portland, Oregon 97227, USA
Ann Intern Med 142:203-11. 2005..Since all trials were conducted in countries other than the United States, generalizability to the U.S. population is uncertain. CONCLUSION: For men age 65 to 75 years, an invitation to attend AAA screening reduces AAA-related mortality...
Repair of small abdominal aortic aneurysmsFrank A Lederle
N Engl J Med 354:1537-8. 2006
Regarding "Informed consent for AAA repair: assessing variations in surgeon opinion through a national survey"Frank A Lederle
J Vasc Surg 48:255; author reply 255. 2008
ACE inhibitors and aortic ruptureFrank A Lederle
Lancet 368:1571; author reply 1572. 2006
