Research Topics
Species | Ramona O HopkinsSummaryAffiliation: LDS Hospital Country: USA Publications
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Publications
Hyperbaric oxygen for acute carbon monoxide poisoningLindell K Weaver
Department of Internal Medicine, Pulmonary and Critical Care Division, LDS Hospital, Salt Lake City, Utah 84143, USA
N Engl J Med 347:1057-67. 2002..Patients with acute carbon monoxide poisoning commonly have cognitive sequelae. We conducted a double-blind, randomized trial to evaluate the effect of hyperbaric-oxygen treatment on such cognitive sequelae...- Brain atrophy and cognitive impairment in survivors of Acute Respiratory Distress SyndromeRamona O Hopkins
Psychology Department and Neuroscience Center, Brigham Young University, Provo, Utah, USA
Brain Inj 20:263-71. 2006..It also compared the medical and cognitive outcome data of patients with ARDS with and without CT scans... - Two-year cognitive, emotional, and quality-of-life outcomes in acute respiratory distress syndromeRamona O Hopkins
Department of Critical Care Medicine, LDS Hospital, Eighth Avenue and C Street, Salt Lake City, UT 84602
Am J Respir Crit Care Med 171:340-7. 2005..ARDS can cause significant long-term, brain-related morbidity manifest by neurocognitive impairments and decreased quality of life... - Chronic neurocognitive effects of critical illnessRamona O Hopkins
Psychology Department and Neuroscience Center, Brigham Young University, Provo, Utah, USA
Curr Opin Crit Care 11:369-75. 2005..This paper examines the current evidence for neurocognitive impairments in survivors of critical illness... - Quality of life, emotional, and cognitive function following acute respiratory distress syndromeRamona O Hopkins
Department of Medicine, Pulmonary and Critical Care Divisions, LDS Hospital, Salt Lake City, Utah, USA
J Int Neuropsychol Soc 10:1005-17. 2004..ARDS is common and may result in significant cognitive and emotional morbidity and decreased quality of life... 
Risk factors for depression and anxiety in survivors of acute respiratory distress syndromeRamona O Hopkins
Pulmonary and Critical Care Division, Department of Medicine, LDS Hospital, Salt Lake City, UT 84107, USA
Gen Hosp Psychiatry 32:147-55. 2010..Depression and anxiety are common morbidities of critical illness. We assessed risk factors of depression and anxiety in Acute Respiratory Distress Syndrome (ARDS) survivors at 1 and 2 years post-hospital discharge...- Neurologic changes during critical illness: brain imaging findings and neurobehavioral outcomesMary R Suchyta
Department of Medicine, Pulmonary and Critical Care Division, LDS Hospital, Salt Lake City, UT, USA
Brain Imaging Behav 4:22-34. 2010..This study further illustrates the adverse effects of critical illness on the brain and highlights the need for additional research in this emerging area... - Blood glucose dysregulation and cognitive outcome in ARDS survivorsRamona O Hopkins
Department of Medicine, Pulmonary and Critical Care Division, LDS Hospital, Salt Lake City, Utah, USA
Brain Inj 24:1478-84. 2010..This study assessed the impact of blood glucose on cognitive outcome in acute respiratory distress syndrome (ARDS) patients' 1 year post-hospital discharge... - Different patterns of cerebral activation in genuine and malingered cognitive effort during performance on the Word Memory TestJames D Larsen
Psychology Department, Brigham Young University, Provo, Utah 84602, USA
Brain Inj 24:89-99. 2010..The second purpose was to investigate the neural networks involved during intentional malingering on the WMT... - Transforming ICU culture to facilitate early mobilityRamona O Hopkins
Department of Medicine, Pulmonary and Critical Care Division, LDS Hospital, Eighth Avenue and C Street, Salt Lake City, UT 84143, USA
Crit Care Clin 23:81-96. 2007..Involvement of front-line staff in early mobility and other components of the care process model resulted in the development of a culture of safety and teamwork... - Spatial memory deficits in a virtual radial arm maze in amnesic participants with hippocampal damageNaomi J Goodrich-Hunsaker
Department of Physiology and Developmental Biology, Brigham Young University, USA
Behav Neurosci 124:405-13. 2010..These data are analogous to previous animal research. Overall, the human hippocampus is necessary for spatial memory and navigation in a virtual radial arm maze task... - Apolipoprotein E genotype and response of carbon monoxide poisoning to hyperbaric oxygen treatmentRamona O Hopkins
Psychology Department and Neuroscience Center, Brigham Young University, Provo, Utah, USA
Am J Respir Crit Care Med 176:1001-6. 2007..The apolipoprotein (APOE) epsilon4 allele predicts unfavorable neurologic outcome after brain injury and stroke... - The role of future longitudinal studies in ICU survivors: understanding determinants and pathophysiology of brain dysfunctionRamona O Hopkins
Psychology Department and Neuroscience Center, Brigham Young University, Provo, USA
Curr Opin Crit Care 13:497-502. 2007..In this paper, we examine important areas of investigation heretofore unaddressed and propose directions for clinically oriented outcomes research... - Cognitive sequelae in acute respiratory distress syndrome patients with and without recall of the intensive care unitMichael J Larson
Psychology Department, Brigham Young University, Provo, Utah, USA
J Int Neuropsychol Soc 13:595-605. 2007..Estimated premorbid intelligence scores were inversely related to the magnitude of cognitive sequelae, suggesting greater "cognitive reserve" in patients with fewer cognitive decrements... - Patients with respiratory failure increase ambulation after transfer to an intensive care unit where early activity is a priorityGeorge E Thomsen
Department of Medicine, LDS Hospital, Salt Lake City, UT, USA
Crit Care Med 36:1119-24. 2008..We hypothesized that ambulation of patients with acute respiratory failure would increase with transfer to an intensive care unit where activity is a key component of patient care... - Cognitive and affective outcomes of more severe compared to less severe carbon monoxide poisoningChelsea A Chambers
Psychology Department, Brigham Young University, Provo, Utah, USA
Brain Inj 22:387-95. 2008..To assess cognitive sequelae, depression and anxiety following carbon monoxide (CO) poisoning... - Neuroimaging, cognitive, and neurobehavioral outcomes following carbon monoxide poisoningRamona O Hopkins
Brigham Young University, USA
Behav Cogn Neurosci Rev 5:141-55. 2006..Given the high rate of brain related morbidity and the fact that the majority of carbon monoxide is avoidable, awareness and prevention of carbon monoxide poisoning is warranted... - Clinical rating of cortical atrophy and cognitive correlates following traumatic brain injuryAdam G Bergeson
Neuroscience Center, Brigham Young University, Provo, UT 84602-5543, USA
Clin Neuropsychol 18:509-20. 2004..These findings indicate that clinical ratings of trauma-induced atrophy can be reliably performed and are associated with neuropsychological outcome and quantitative measures of cerebral atrophy... - Substance dependence and psychiatric disorders are related to outcomes in a mixed ICU populationMary R Suchyta
Department of Medicine, Pulmonary and Critical Care Division, LDS Hospital, Salt Lake City, UT, USA
Intensive Care Med 34:2264-7. 2008..We also compared the prevalence of substance dependence and psychiatric disorders to population data... - Spatial deficits in a virtual water maze in amnesic participants with hippocampal damageNaomi J Goodrich-Hunsaker
Department of Physiology and Developmental Biology, Brigham Young University, Provo, Utah 84602, USA
Hippocampus 20:481-91. 2010..These results not only confirm that the hippocampus plays a necessary role in human navigation in large-scale environments but also provides a new link between the mnemonic and navigational roles of the hippocampus... - Quality of life, emotional abnormalities, and cognitive dysfunction in survivors of acute lung injury/acute respiratory distress syndromeRamona O Hopkins
Department of Medicine, Pulmonary and Critical Care Division, LDS Hospital, Salt Lake City, UT 84143, USA
Clin Chest Med 27:679-89; abstract x. 2006..Its main focus is a review of the current knowledge concerning cognitive and emotional outcomes after lung injury and their impact on long-term quality of life... - Early activity is feasible and safe in respiratory failure patientsPolly Bailey
Department of Medicine, Pulmonary and Critical Care Division, LDS Hospital, Salt Lake City, UT, USA
Crit Care Med 35:139-45. 2007..To determine whether early activity is feasible and safe in respiratory failure patients... - Pulmonary function and health-related quality of life in survivors of acute respiratory distress syndromeJames Orme
Department of Medicine, Pulmonary and Critical Care Divisions, LDS Hospital, Salt Lake City, Utah 84143, USA
Am J Respir Crit Care Med 167:690-4. 2003..Acute respiratory distress syndrome survivors treated with high and low tidal volumes have abnormal pulmonary function that was related to decreased health-related quality of life 1 year after hospital discharge... 
Cognitive, emotional, and quality of life outcomes in patients with pulmonary arterial hypertensionJoanne White
Psychology Department, Brigham Young University, Provo, Utah, USA
Respir Res 7:55. 2006..Our secondary purpose was to determine the relationships between cognitive sequelae and neuropsychological test scores with depression, anxiety, and quality of life...- Sequences assessed by declarative and procedural tests of memory in amnesic patients with hippocampal damageRamona O Hopkins
Psychology Department and Neuroscience Center, 1122 SWKT, Brigham Young University, Provo, UT 84602, USA
Neuropsychologia 42:1877-86. 2004..The performance differences on the two sequence learning tasks are likely due to the use of different strategies associated with learning sequences based on procedural versus declarative knowledge... - Functional neuroimaging evidence for high cognitive effort on the Word Memory Test in the absence of external incentivesMark D Allen
Psychology Department, Brigham Young University, Provo, UT 84602, USA
Brain Inj 21:1425-8. 2007.... - Word memory test performance in amnesic patients with hippocampal damageNaomi J Goodrich-Hunsaker
Department of Physiology Brigham Young University, Provo, UT 84602, USA
Neuropsychology 23:529-34. 2009..Such an approach where SVT performance is assessed in populations with well-known cognitive impairments adds breadth to SVT clinical interpretations... - Short- and long-term cognitive outcomes in intensive care unit survivorsRamona O Hopkins
Psychology Department, Neuroscience Center, Brigham Young University, Provo, UT, USA
Clin Chest Med 30:143-53, ix. 2009.... - The role of the human hippocampus in odor-place associative memoryNaomi J Goodrich-Hunsaker
1Department of Physiology and Developmental Biology, Brigham Young University, Provo, UT 84602, USA
Chem Senses 34:513-21. 2009..These data provide support for the idea that odor-place associative memory is mediated by the hippocampus in both humans and rodents, suggesting an evolutionary continuity in cognitive function assigned to the hippocampus... - Carbon monoxide poisoning: risk factors for cognitive sequelae and the role of hyperbaric oxygenLindell K Weaver
Department of Internal Medicine, Pulmonary and Critical Care Division, Intermountain Healthcare, Salt Lake City, Utah, USA
Am J Respir Crit Care Med 176:491-7. 2007..Carbon monoxide poisoning is common and causes cognitive sequelae. Hyperbaric oxygen (HBO(2)) reduces cognitive sequelae incidence, but which patients may benefit from HBO(2) is unclear... - Anoxic versus traumatic brain injury: amount of tissue loss, not etiology, alters cognitive and emotional functionRamona O Hopkins
Psychology Department, Neuroscience Center, Brigham Young University, Provo, UT 84602, USA
Neuropsychology 19:233-42. 2005..In the absence of localized lesions, the amount of neural tissue loss, rather than etiology, may be the critical factor in neuropsychological outcome... - Strategies for promoting early activity in critically ill mechanically ventilated patientsRamona O Hopkins
Brigham Young University, Provo, Utah, USA
AACN Adv Crit Care 20:277-89. 2009..ICU culture can be transformed in a way that leads to improved and more reliable treatments and care, including early activity and mobility... - Affective outcome following carbon monoxide poisoning: a prospective longitudinal studyBruce W Jasper
Psychology Department, Brigham Young University, Provo, Utah 84604, USA
Cogn Behav Neurol 18:127-34. 2005..Clinicians need to be aware of affective morbidity following CO poisoning and remain vigilant about CO prevention... - Carbon Monoxide Research Group, LDS Hospital, Utah in reply to Scheinkestel et al. and Emerson: the role of hyperbaric oxygen in carbon monoxide poisoningLindell K Weaver
Department of Medicine, Pulmonary Critical Care Divisions, LDS Hospital, Salt Lake City, Utah, USA
Emerg Med Australas 16:394-9; discussion 481-2. 2004..and the accompanying Commentary: 'The dilemma of managing carbon monoxide poisoning' by Emerson published in the April issue of Emergency Medicine Australasia... - Mnemonic functions of the hippocampus: a comparison between animals and humansRaymond P Kesner
Department of Psychology, University of Utah, Salt Lake City, 84112, USA
Biol Psychol 73:3-18. 2006..These data provide support for evolutionary continuity in cognitive function assigned to the hippocampus of rats and humans... 
Pattern separation deficits following damage to the hippocampusC Brock Kirwan
Department of Psychology, Brigham Young University, 1001 Kimball Tower, Provo, UT 84602 5543, USA
Neuropsychologia 50:2408-14. 2012..However, patients were less likely to uniquely identify lures as "similar" than matched controls, indicating an impairment in pattern separation processes following damage to the hippocampus...- Memory, visual discrimination performance, and the human hippocampusSoyun Kim
Department of Psychiatry, Brigham Young University, Provo, Utah 84602, USA
J Neurosci 31:2624-9. 2011..The findings support the fundamental idea that memory is a distinct cerebral function separable from other perceptual and cognitive abilities... - Prevalence of white matter hyperintensities in a young healthy populationRamona O Hopkins
Psychology Department, Brigham Young University, Provo, UT 84602, USA
J Neuroimaging 16:243-51. 2006..We assessed the prevalence of WMHs in a cohort of younger healthy subjects... - Long-term neurocognitive function after critical illnessRamona O Hopkins
Department of Internal Medicine, Critical Care Medicine, LDS Hospital, Eighth Ave and C St, Salt Lake City, UT 84143, USA
Chest 130:869-78. 2006..However, neurocognitive outcomes have been the subject of extensive investigation in other medical populations for many years... - Neurobehavioral Grand Rounds introduction: Does near drowning in ice water prevent anoxic induced brain injury?Ramona O Hopkins
Psychology Department and Neuroscience Center, Brigham Young University, Provo, Utah 84602, USA
J Int Neuropsychol Soc 14:656-9. 2008.... - Basal ganglia lesions following carbon monoxide poisoningRamona O Hopkins
Pyschology Department, Brigham Young University, Provo, Utah 84602 5543, USA
Brain Inj 20:273-81. 2006..Research design: Literature review and prospective cohort study... - Physical therapy on the wards after early physical activity and mobility in the intensive care unitRamona O Hopkins
Department of Medicine, Pulmonary and Critical Care, Intermountain Medical Center, 5121 S Cottonwood St, Murray, UT 84107, USA
Phys Ther 92:1518-23. 2012..Weakness and debilitation are common following critical illness. Studies that assess whether early physical activity initiated in the intensive care unit (ICU) continues after a patient is transferred to a ward are lacking... - Visual working memory capacity and the medial temporal lobeAnnette Jeneson
Departments of Psychology, Psychiatry, and Neurosciences, University of California, San Diego, California 92093, USA
J Neurosci 32:3584-9. 2012.... - Assessing neurocognitive outcomes after critical illness: are delirium and long-term cognitive impairments related?Ramona O Hopkins
Psychology Department and Neuroscience Center, Brigham Young University, Provo, USA
Curr Opin Crit Care 12:388-94. 2006..In this paper we examine possible relationships between delirium and long-term cognitive impairments and explore this in the context of critical illness... - Neuropsychological and neuropathological effects of anoxic or ischemic induced brain injuryRamona O Hopkins
Psychology Department, 1122 SWKT, Brigham Young University, Provo, UT 84602, USA
J Int Neuropsychol Soc 10:957-61. 2004 - Hypothermia-induced platelet aggregation and cognitive decline in coronary artery bypass surgery: a pilot studyMatthew W Hall
Department of Chemical Engineering, 350 CB, Brigham Young University, Provo, UT 84602, USA
Perfusion 20:157-67. 2005..The findings of our study suggest the long-term cognitive effects of hypothermia-induced platelet aggregation need to be explored... - Sleep and cognitive performance of flight nurses after 12-hour evening versus 18-hour shiftsFrank Thomas
Department of Medicine, Pulmonary and Critical Care Division, LDS Hospital, Salt Lake City, Utah 84143, USA
Air Med J 25:216-25. 2006..Using a prospective within-subjects design, this study compared the amount of daily sleep and the cognitive performance in flight nurses working 12-hour evening versus 18-hour shifts during a 72-hour duty schedule... - Neuroimaging of anoxic injury: implications for neurorehabilitationRamona O Hopkins
Psychology Department, Brigham Young University, Provo, UT 84093, USA
NeuroRehabilitation 31:319-29. 2012..Research is needed to understand cognitive and functional outcomes following ABI as well as whether specific rehabilitation techniques or strategies will result in better outcomes... - Neuroimaging after critical illness: implications for neurorehabilitation outcomeRamona O Hopkins
Psychology Department, Brigham Young University, Provo, UT, USA
NeuroRehabilitation 31:311-8. 2012.... - Impaired probabilistic category learning in hypoxic subjects with hippocampal damageRamona O Hopkins
Psychology Department and Neuroscience Center, Brigham Young University, Provo, UT, USA
Neuropsychologia 42:524-35. 2004..These results may suggest a qualification of the generally held conclusion that amnesic patients are not impaired at probabilistic category learning: at least under some circumstances, amnesic patients show an early and lasting deficit... - Clinical identification of cognitive impairment in ICU survivors: insights for intensivistsSharon M Gordon
Center for Health Services Research, Vanderbilt University, 6100 Medical Center East, Nashville, TN 37232, USA
Intensive Care Med 30:1997-2008. 2004..However, it can be identified by objective (test scores) or subjective evidence (clinical judgment, patient observation, family interaction)... - Effects of hypoxia on the brain: neuroimaging and neuropsychological findings following carbon monoxide poisoning and obstructive sleep apneaShawn D Gale
Department of Clinical Neuropsychology, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona 85013, USA
J Int Neuropsychol Soc 10:60-71. 2004..The observed group differences provide insight into the relationship between etiology of injury, neuropathological changes, and clinical presentation... - Learning and generalization deficits in patients with memory impairments due to anterior communicating artery aneurysm rupture or hypoxic brain injuryCatherine E Myers
Department of Psychology, Rutgers University Newark, Newark, NJ 07102, USA
Neuropsychology 22:681-6. 2008..These results highlight a difference in feedback-based learning in 2 amnesic etiologies, despite similar levels of declarative memory impairment... - Validation of a brief telephone battery for neurocognitive assessment of patients with pulmonary arterial hypertensionDarren B Taichman
Pulmonary, Allergy and Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Respir Res 6:39. 2005..We undertook this study to validate telephone administration of the tests... - Recognition memory and the human hippocampusJoseph R Manns
University of California, San Diego, La Jolla, CA 92093, USA
Neuron 37:171-80. 2003.... - Traumatic brain injury and atrophy of the cingulate gyrusRyan Yount
Department of Psychology, University of San Francisco, San Francisco, CA, USA
J Neuropsychiatry Clin Neurosci 14:416-23. 2002..Despite significant atrophy of the posterior CG, neuropsychological performance was not related to changes in CG cross-sectional surface area in the TBI subjects. This apparent discrepancy is discussed... - Does critical illness and intensive care unit treatment contribute to neurocognitive and functional morbidity in pediatric patients?Ramona O Hopkins
J Pediatr (Rio J) 83:488-90. 2007 - Research issues in the evaluation of cognitive impairment in intensive care unit survivorsJames C Jackson
Division of Allergy, Pulmonary and Critical Care Medicine, T 1218 Medical Center North, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
Intensive Care Med 30:2009-16. 2004.... - Impaired visual and odor recognition memory span in patients with hippocampal lesionsDaniel A Levy
Veterans Affairs Healthcare System, San Diego, California 92161, USA
Learn Mem 10:531-6. 2003..The patients were impaired on all three tasks. We consider possible explanations for the difference between the findings for humans and rats, including the fact that olfactory function is particularly well-developed in rodents... - Spatial memory and the human hippocampusYael Shrager
Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093, USA
Proc Natl Acad Sci U S A 104:2961-6. 2007..We conclude that damage to the hippocampus does not selectively impair viewpoint-independent spatial memory. Rather, hippocampal damage impairs memory as the memory load increases... - Post-traumatic stress disorder and post-traumatic stress symptoms following critical illness in medical intensive care unit patients: assessing the magnitude of the problemJames C Jackson
Clinical Research Center of Excellence, VA Tennessee Valley Geriatric Research, Education and Clinical Center, Nashville, TN 37212, USA
Crit Care 11:R27. 2007..Recently, investigators have reported that the experience of critical illness can also lead to PTSD, although details of the association between critical illness and PTSD remain unclear... - The association between delirium and cognitive decline: a review of the empirical literatureJames C Jackson
Division of Allergy Pulmonary Critical Care Medicine, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 8300, USA
Neuropsychol Rev 14:87-98. 2004..Additional research on delirium-related effects on long-term cognitive outcome is needed... - Impaired odor recognition memory in patients with hippocampal lesionsDaniel A Levy
Veterans Affairs Healthcare System, San Diego, California 92161, USA
Learn Mem 11:794-6. 2004..Olfactory recognition memory, similar to recognition memory in other sensory modalities, depends on the integrity of the hippocampal region... - The hippocampus supports both the recollection and the familiarity components of recognition memoryPeter E Wais
Department of Psychology, University of California, San Diego, La Jolla, California 92093, USA
Neuron 49:459-66. 2006..These results suggest that the component processes that determine the shape of the ROC are operative in the absence of the hippocampus, and they argue against the idea that the hippocampus selectively supports the recollection process... - The pathophysiology of long-term neuromuscular and cognitive outcomes following critical illnessMargaret S Herridge
Pulmonary and Critical Care Medicine, University of Toronto, Toronto General Hospital, Toronto, Ontario, Canada M5G 2C4
Crit Care Clin 24:179-99, x. 2008..Additionally, it presents a roadmap outlining future directions in this area of research... - Item memory, source memory, and the medial temporal lobe: concordant findings from fMRI and memory-impaired patientsJeffrey J Gold
Veterans Affairs Medical Center, San Diego, CA 92161, USA
Proc Natl Acad Sci U S A 103:9351-6. 2006..Together, the findings suggest that medial temporal lobe structures broadly support recognition memory function and that item memory and source memory similarly depend on these structures... - The neuroanatomy of remote memoryPeter J Bayley
University of California, San Diego, La Jolla, California 92093, USA
Neuron 46:799-810. 2005.... - Working memory and the organization of brain systemsYael Shrager
University of California, San Diego, La Jolla, California 92093, USA
J Neurosci 28:4818-22. 2008..These findings support the conclusion that working memory (active maintenance) is intact after medial temporal lobe damage... - Formation and validation of a telephone battery to assess cognitive function in acute respiratory distress syndrome survivorsJason D Christie
Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Crit Care 21:125-32. 2006..Describe initial development and validation of a test battery composed of established instruments designed to detect, via telephone interview, cognitive abnormalities in survivors of acute respiratory distress syndrome... - Hemorrhagic infarction in white matter following acute carbon monoxide poisoningLindell K Weaver
Neurology 64:1101; author reply 1101. 2005 - Hippocampal and ventricular volumes in psychotic and nonpsychotic bipolar patients compared with schizophrenia patients and community control subjects: a pilot studyHeather C Strasser
Division of Psychiatric Neuroimaging, Johns Hopkins University, Baltimore, Catonsville, Maryland
Biol Psychiatry 57:633-9. 2005..CONCLUSIONS: These results suggest that PBP but not NPBP is associated with increased ventricle volumes and a trend toward smaller left hippocampal volumes, as observed in SZ... - Intact visual perception in memory-impaired patients with medial temporal lobe lesionsYael Shrager
Department of Neurosciences, University of California, San Diego, La Jolla, California 92093, USA
J Neurosci 26:2235-40. 2006..Furthermore, the results support the principle that the ability to acquire new memories is a distinct cerebral function, dissociable from other perceptual and cognitive functions...