R D Christensen

Summary

Affiliation: LDS Hospital
Country: USA

Publications

  1. ncbi request reprint A pilot trial testing the feasibility of administering D-penicillamine to extremely low birth weight neonates
    R D Christensen
    Department of Women and Newborn, Intermountain Health Care and the McKay Dee Hospital Center, Ogden, UT 84403, USA
    J Perinatol 26:120-4. 2006
  2. ncbi request reprint Center differences in NEC within one health-care system may depend on feeding protocol
    Susan E Wiedmeier
    LDS Hospital and the University of Utah School of Medicine, Salt Lake City, Utah
    Am J Perinatol 25:5-11. 2008
  3. doi request reprint A de novo T73I mutation in PTPN11 in a neonate with severe and prolonged congenital thrombocytopenia and Noonan syndrome
    Robert D Christensen
    Department of Women and Newborns, Intermountain Healthcare, University of Utah School of Medicine, Salt Lake City, Utah 84403, USA
    Neonatology 104:1-5. 2013
  4. ncbi request reprint A neonate with congenital amegakaryocytic thrombocytopenia associated with a chromosomal microdeletion at 21q22.11 including the gene RUNX1
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Ogden, UT 84403, USA
    J Perinatol 33:242-4. 2013
  5. doi request reprint Severe neonatal anemia from fetomaternal hemorrhage: report from a multihospital health-care system
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 33:429-34. 2013
  6. doi request reprint Neonates presenting with bloody stools and eosinophilia can progress to two different types of necrotizing enterocolitis
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 32:874-9. 2012
  7. doi request reprint Unexplained extreme hyperbilirubinemia among neonates in a multihospital healthcare system
    Robert D Christensen
    Women and Newborn s Clinical Program, Intermountain Healthcare, Salt Lake City, UT, USA
    Blood Cells Mol Dis 50:105-9. 2013
  8. doi request reprint Reference ranges for lymphocyte counts of neonates: associations between abnormal counts and outcomes
    Robert D Christensen
    Women and Newborn s Clinical Program, Intermountain Healthcare, Ogden, Utah 84403, USA
    Pediatrics 129:e1165-72. 2012
  9. doi request reprint A neonate with the Pelger-Huët anomaly, cleft lip and palate, and agenesis of the corpus callosum, with a chromosomal microdeletion involving 1q41 to 1q42.12
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT 84403, USA
    J Perinatol 32:238-40. 2012
  10. ncbi request reprint Necrotizing enterocolitis in term neonates: data from a multihospital health-care system
    D K Lambert
    Intermountain Health Care, Ogden, UT 84403, USA
    J Perinatol 27:437-43. 2007

Collaborators

Detail Information

Publications110 found, 100 shown here

  1. ncbi request reprint A pilot trial testing the feasibility of administering D-penicillamine to extremely low birth weight neonates
    R D Christensen
    Department of Women and Newborn, Intermountain Health Care and the McKay Dee Hospital Center, Ogden, UT 84403, USA
    J Perinatol 26:120-4. 2006
    ....
  2. ncbi request reprint Center differences in NEC within one health-care system may depend on feeding protocol
    Susan E Wiedmeier
    LDS Hospital and the University of Utah School of Medicine, Salt Lake City, Utah
    Am J Perinatol 25:5-11. 2008
    ..Changing the feeding practices at Center A to those at Centers B and C is planned to test this theory...
  3. doi request reprint A de novo T73I mutation in PTPN11 in a neonate with severe and prolonged congenital thrombocytopenia and Noonan syndrome
    Robert D Christensen
    Department of Women and Newborns, Intermountain Healthcare, University of Utah School of Medicine, Salt Lake City, Utah 84403, USA
    Neonatology 104:1-5. 2013
    ..We propose this specific PTPN11 mutation results in abnormalities of the protein product SHP-2, which, because of its role in signal transduction, results in severe congenital thrombocytopenia refractory to c-MPL agonists. ..
  4. ncbi request reprint A neonate with congenital amegakaryocytic thrombocytopenia associated with a chromosomal microdeletion at 21q22.11 including the gene RUNX1
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Ogden, UT 84403, USA
    J Perinatol 33:242-4. 2013
    ..We propose that a 21q22 deletion resulting in RUNX1 haploinsufficiency can produce a phenotype similar to CAMT with various associated anomalies depending on which adjacent genes are absent or disrupted...
  5. doi request reprint Severe neonatal anemia from fetomaternal hemorrhage: report from a multihospital health-care system
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 33:429-34. 2013
    ..We performed a large, muiticentered, sequential, case series to determine the incidence, antecedents and outcomes...
  6. doi request reprint Neonates presenting with bloody stools and eosinophilia can progress to two different types of necrotizing enterocolitis
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 32:874-9. 2012
    ..We hypothesized that neonates with bloody stools and concomitant eosinophilia are likely to have atopic enteropathy rather than necrotizing enterocolitis (NEC)...
  7. doi request reprint Unexplained extreme hyperbilirubinemia among neonates in a multihospital healthcare system
    Robert D Christensen
    Women and Newborn s Clinical Program, Intermountain Healthcare, Salt Lake City, UT, USA
    Blood Cells Mol Dis 50:105-9. 2013
    ..With this in mind, we propose a "consistent approach" to evaluating the cause(s) of hyperbilirubinemia among neonates with a TSB >25mg/dL...
  8. doi request reprint Reference ranges for lymphocyte counts of neonates: associations between abnormal counts and outcomes
    Robert D Christensen
    Women and Newborn s Clinical Program, Intermountain Healthcare, Ogden, Utah 84403, USA
    Pediatrics 129:e1165-72. 2012
    ....
  9. doi request reprint A neonate with the Pelger-Huët anomaly, cleft lip and palate, and agenesis of the corpus callosum, with a chromosomal microdeletion involving 1q41 to 1q42.12
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT 84403, USA
    J Perinatol 32:238-40. 2012
    ..A chromosomal microdeletion was identified at1q41-42.12...
  10. ncbi request reprint Necrotizing enterocolitis in term neonates: data from a multihospital health-care system
    D K Lambert
    Intermountain Health Care, Ogden, UT 84403, USA
    J Perinatol 27:437-43. 2007
    ....
  11. ncbi request reprint Reference ranges for blood concentrations of eosinophils and monocytes during the neonatal period defined from over 63 000 records in a multihospital health-care system
    R D Christensen
    Intermountain Healthcare Women and Newborns Clinical Program, Ogden, UT, USA 2 McKay Dee Hospital Center, Ogden, UT, USA
    J Perinatol 30:540-5. 2010
    ..Reference ranges for these concentrations during the neonatal period, established by very large sample sizes and modern methods, are needed for identifying abnormally low or high values...
  12. ncbi request reprint Is "transfusion-associated necrotizing enterocolitis" an authentic pathogenic entity?
    Robert D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Ogden, Utah 84403, USA
    Transfusion 50:1106-12. 2010
    ..Necrotizing enterocolitis (NEC) sometimes occurs after a transfusion, but it is unclear whether this is a chance association or cause and effect...
  13. ncbi request reprint West Nile virus in 2006 and 2007: the Canadian Blood Services' experience
    Sheila F O'Brien
    Canadian Blood Services, Ottawa, Ontario, Canada
    Transfusion 50:1118-25. 2010
    ..In 2007, Canada experienced a larger epidemic than in previous years providing an opportunity to evaluate the ID-NAT triggering algorithm in higher-risk areas...
  14. doi request reprint Hereditary spherocytosis in neonates with hyperbilirubinemia
    Robert D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, Utah 84403, USA
    Pediatrics 125:120-5. 2010
    ..Neonates with HS can develop significant hyperbilirubinemia, but we suspect that HS is underrecognized as a cause of neonatal jaundice...
  15. ncbi request reprint Identifying patients, on the first day of life, at high-risk of developing parenteral nutrition-associated liver disease
    R D Christensen
    Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 27:284-90. 2007
    ..Therefore, preparatory to devising studies of prophylaxis against PNALD, we conducted an evaluation of all NICU patients who received PN for >or=14 day, assessing their likelihood of developing PNALD...
  16. ncbi request reprint Advances and controversies in neonatal ICU platelet transfusion practice
    Robert D Christensen
    Intermountain Healthcare, 36 S State Street, Salt Lake City, UT, USA
    Adv Pediatr 55:255-69. 2008
    ..Only that type of study is likely to generate the evidence base needed for widespread implementation of improvements in NICU platelet transfusion practice...
  17. ncbi request reprint Case report: perianal necrotizing fasciitis in a near-term neonate
    R D Christensen
    Intermountain Healthcare, Neonatology, Ogden and Salt Lake City, UT 84403, USA
    J Perinatol 27:390-1. 2007
    ..Each probe sheath cover examined had three areas that, in our opinion, could possibly generate a minor mucosal injury...
  18. doi request reprint Antecedents of Bell stage III necrotizing enterocolitis
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT 84403, USA
    J Perinatol 30:54-7. 2010
    ..This study was undertaken to assess this issue based on data from every case of Bell stage III NEC cared for during the past 7 years at Intermountain Healthcare...
  19. doi request reprint Can we cut the incidence of necrotizing enterocolitis in half--today?
    Robert D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Ogden and Salt Lake City, Utah, USA
    Fetal Pediatr Pathol 29:185-98. 2010
    ....
  20. doi request reprint Postponing or eliminating red blood cell transfusions of very low birth weight neonates by obtaining all baseline laboratory blood tests from otherwise discarded fetal blood in the placenta
    Robert D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, Utah 84403, USA
    Transfusion 51:253-8. 2011
    ..Safely reducing the proportion of very low birth weight neonates (<1500 g) that receive a red blood cell (RBC) transfusion would be an advance in transfusion practice...
  21. ncbi request reprint D-Penicillamine administration and the incidence of retinopathy of prematurity
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, McKay Dee Hospital Center, Ogden, UT 84403, USA
    J Perinatol 27:103-11. 2007
    ..We compared the development of retinopathy of prematurity (ROP) among 49 preterm neonates:; 15 who were treated during the first 2 weeks of life with D-penicillamine and 34 who were not...
  22. doi request reprint Six children with pyruvate kinase deficiency from one small town: molecular characterization of the PK-LR gene
    Robert D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT, USA
    J Pediatr 159:695-7. 2011
    ..Six were found to be homozygous for the mutation 1529G-A (510 Arg-Gln). Two previously thought to have pyruvate kinase deficiency did not, because they were heterozygous...
  23. ncbi request reprint An unusual case of severe neonatal thrombocytopenia
    Cindy K Barney
    Neonatal Intensive Care Unit, McKay Dee Hospital, Intermountain Health Care, 4401 Harrison Boulevard, Ogden, UT 84403, USA
    Adv Neonatal Care 7:66-8. 2007
    ..The patient's platelet count remains normal at a 2-year follow-up. This case is reported as an instructive atypical case of NAIT, in which the relevant platelet antigen could not be identified...
  24. ncbi request reprint Comparing two methods of delivering high-flow gas therapy by nasal cannula following endotracheal extubation: a prospective, randomized, masked, crossover trial
    D D Woodhead
    Intermountain Healthcare, McKay Dee Hospital, Ogden, UT 84403, USA
    J Perinatol 26:481-5. 2006
    ..We compared two methods of delivering high-flow gas therapy by nasal cannula, applied immediately after planned endotracheal extubations of NICU patients...
  25. doi request reprint Platelet transfusion in the neonatal intensive care unit: benefits, risks, alternatives
    Robert D Christensen
    Women and Newborns Program, Intermountain Healthcare, Ogden, UT 84403, USA
    Neonatology 100:311-8. 2011
    ..Initiating specific programs to improve compliance with transfusion guidelines can further improve NICU transfusion practice...
  26. doi request reprint Reference ranges for blood concentrations of nucleated red blood cells in neonates
    Robert D Christensen
    Women and Newborn s Clinical Program, Intermountain Healthcare, Ogden, Utah 84403, USA
    Neonatology 99:289-94. 2011
    ..Previous studies reported a relationship between high nucleated red blood cells (NRBC) in neonates and the development of intraventricular hemorrhage (IVH) and/or retinopathy of prematurity (ROP)...
  27. ncbi request reprint A low-sodium solution for airway care: results of a multicenter trial
    Robert D Christensen
    Neonatal Intensive Care, McKay Dee Hospital Center, Intermountain Healthcare, 4403 Harrison Boulevard, Ogden, UT 84403, USA
    Respir Care 55:1680-5. 2010
    ..We now report a multicenter trial of that solution...
  28. ncbi request reprint Necrotizing enterocolitis during the first week of life: a multicentered case-control and cohort comparison study
    G Stout
    Neonatology, Intermountain Healthcare, Ogden, UT 84403, USA
    J Perinatol 28:556-60. 2008
    ..To test this, we sought to identify every case of NEC diagnosed during the first week within the Intermountain Healthcare system during the most recent 6-year period...
  29. doi request reprint Adherence to NICU transfusion guidelines: data from a multihospital healthcare system
    V L Baer
    Intermountain Healthcare, Ogden, UT 84403, USA
    J Perinatol 28:492-7. 2008
    ....
  30. doi request reprint Fulminant necrotizing enterocolitis in a multihospital healthcare system
    D K Lambert
    Women and Newborns Program, Intermountain Healthcare, Salt Lake City, UT 84403, USA
    J Perinatol 32:194-8. 2012
    ..We sought to identify and report all such cases in a multihospital healthcare system during the past 9 years and to characterize this entity using case-control methodologies...
  31. ncbi request reprint Thrombocytopenia among extremely low birth weight neonates: data from a multihospital healthcare system
    R D Christensen
    Intermountain Healthcare Clinical Research, McKay Dee Hospital Center, Ogden, UT 84403, USA
    J Perinatol 26:348-53. 2006
    ..However, little is known about thrombocytopenia in the ELBW population. We sought to determine the incidence, timing, causes, platelet transfusions given, and outcomes of thrombocytopenia among ELBW neonates...
  32. doi request reprint Effect of ampicillin on bleeding time in very low birth-weight neonates during the first week after birth
    M J Sheffield
    Intermountain Healthcare, McKay Dee Hospital Center, Ogden, UT 84403, USA
    J Perinatol 31:477-80. 2011
    ..Ampicillin can prolong the bleeding times of term and late preterm neonates, but its effect on VLBW neonates, who already have a somewhat prolonged bleeding time initially, is not known...
  33. ncbi request reprint Isolated elevated blood neutrophil concentration at altitude does not require NICU admission if appropriate reference ranges are used
    R M Lambert
    Intermountain Healthcare, Ogden, UT 84403, USA
    J Perinatol 29:822-5. 2009
    ..On this basis, we speculated that some well babies with risk factors for infection are mistakenly judged as having an abnormal CBC, and are unnecessarily admitted to the NICU...
  34. ncbi request reprint ETCare: a randomized, controlled, masked trial comparing two solutions for upper airway care in the NICU
    R D Christensen
    Neonatal Intensive Care, McKay Dee Hospital Center, Intermountain Healthcare, Ogden, UT 84403, USA
    J Perinatol 27:479-84. 2007
    ....
  35. doi request reprint Platelet reference ranges for neonates, defined using data from over 47,000 patients in a multihospital healthcare system
    S E Wiedmeier
    Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 29:130-6. 2009
    ..However, the published reference ranges for platelet counts in neonates may be imprecise, as they were generated from relatively small sample sizes and compiled before modern platelet enumeration methods...
  36. ncbi request reprint Do platelet transfusions in the NICU adversely affect survival? Analysis of 1600 thrombocytopenic neonates in a multihospital healthcare system
    V L Baer
    Department of Women and Newborns, Intermountain Healthcare, McKay Dee Hospital Center, Ogden, UT, USA
    J Perinatol 27:790-6. 2007
    ..The number of platelet transfusions might be a marker for level of illness, and thus predictive of mortality. However, an alternative hypothesis is that multiple platelet transfusions themselves are harmful in this population...
  37. ncbi request reprint Urinary excretion of darbepoetin after intravenous vs subcutaneous administration to preterm neonates
    T L Warwood
    Intermountain Healthcare, Neonatology Clinical Research Group, McKay Dee Hospital, 4401 Harrison Boulevard, Ogden, UT 84403, USA
    J Perinatol 26:636-9. 2006
    ..v. dosing result in urinary loss of the drug. However, this theory has not been tested systematically, and no direct comparisons have been made between s.c. and i.v. dosing of darbepoetin in preterm neonates...
  38. doi request reprint Using umbilical cord blood for the initial blood tests of VLBW neonates results in higher hemoglobin and fewer RBC transfusions
    V L Baer
    Women and Newborns Clinical Program, Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 33:363-5. 2013
    ....
  39. doi request reprint Expected ranges for blood neutrophil concentrations of neonates: the Manroe and Mouzinho charts revisited
    N Schmutz
    Intermountain Healthcare, Ogden, UT 84403, USA
    J Perinatol 28:275-81. 2008
    ....
  40. ncbi request reprint Avoiding endotracheal intubation of neonates undergoing laser surgery for retinopathy of prematurity
    D D Woodhead
    Intermountain Healthcare, McKay Dee Hospital Center, Ogden, UT, USA
    J Perinatol 27:209-13. 2007
    ..One of the three level III neonatal intensive care units (NICUs) in the Intermountain Healthcare system initiated a program of using nasopharyngeal prongs, rather than endotracheal intubation, for respiratory support during ROP surgery...
  41. ncbi request reprint Low blood neutrophil concentrations among extremely low birth weight neonates: data from a multihospital health-care system
    R D Christensen
    Intermountain Healthcare Clinical Research, McKay Dee Hospital Center, Ogden, UT, USA
    J Perinatol 26:682-7. 2006
    ..We also tabulated the treatments used for this condition and associations with mortality...
  42. ncbi request reprint Treating feeding intolerance with an enteral solution patterned after human amniotic fluid: a randomized, controlled, masked trial
    C K Barney
    Intermountain Healthcare Neonatology Clinical Research Group and McKay Dee Hospital, Ogden, UT 84033, USA
    J Perinatol 27:28-31. 2007
    ..We speculated that for such patients, feeding tolerance might improve after oral administration of enterocyte growth factors in a sterile, isotonic solution patterned after amniotic fluid...
  43. doi request reprint Whole-blood viscosity in the neonate: effects of gestational age, hematocrit, mean corpuscular volume and umbilical cord milking
    R D Christensen
    1 Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT, USA 2 Department of Women and Newborns, Neonatal Intensive Care Units, McKay Dee Hospital Center, Ogden, UT, USA
    J Perinatol 34:16-21. 2014
    ....
  44. doi request reprint Very low birth weight infants qualifying for a 'late' erythrocyte transfusion: does giving darbepoetin along with the transfusion counteract the transfusion's erythropoietic suppression?
    T L Warwood
    Women and Newborns Clinical Program, Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 31:S17-21. 2011
    ..Red blood cell (RBC) transfusions can suppress erythropoiesis. On this basis, RBC transfusions administered to very low birth weight (VLBW) neonates potentially render them more likely to qualify for a subsequent transfusion...
  45. doi request reprint Thrombocytosis in neonates and young infants: a report of 25 patients with platelet counts of > or = 1000000 microl(-1)
    S E Wiedmeier
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT 84157 7000, USA
    J Perinatol 30:222-6. 2010
    ....
  46. ncbi request reprint Intravenous administration of darbepoetin to NICU patients
    T L Warwood
    Intermountain Healthcare, Neonatology Clinical Research Group, McKay Dee Hospital, Ogden, UT 84403, USA
    J Perinatol 26:296-300. 2006
    ..Darbepoetin can be administered either intravenously (i.v.) or subcutaneously (s.c.). However, no information is available regarding pharmacokinetics and pharmacodynamics following its i.v. administration to neonates...
  47. doi request reprint Pyruvate kinase deficiency as a cause of extreme hyperbilirubinemia in neonates from a polygamist community
    R D Christensen
    Division of Neonatology, Intermountain Healthcare, Salt Lake City, UT 84403, USA
    J Perinatol 30:233-6. 2010
    ..Such cases should be recognized early and managed aggressively to prevent kernicterus...
  48. doi request reprint Hematological abnormalities during the first week of life among neonates with trisomy 18 and trisomy 13: data from a multi-hospital healthcare system
    S E Wiedmeier
    Department of Women and Newborns, Intermountain Healthcare, Institute for Health Care Delivery Research, Salt Lake City, Utah 84143, USA
    Am J Med Genet A 146:312-20. 2008
    ..These data should assist clinicians caring for neonates with trisomy 18 or 13, demonstrating how common hematological abnormalities exist among these patients...
  49. doi request reprint Ibuprofen lysine administration to neonates with a patent ductus arteriosus: effect on platelet plug formation assessed by in vivo and in vitro measurements
    M J Sheffield
    Intermountain Healthcare, McKay Dee Hospital Center, Ogden, UT, USA
    J Perinatol 29:39-43. 2009
    ..Several previous studies indicate that platelet plug formation is impaired after administration of indomethacin, but it is not clear whether a similar impairment occurs following ibuprofen dosing...
  50. ncbi request reprint The erythrocyte indices of neonates, defined using data from over 12,000 patients in a multihospital health care system
    R D Christensen
    Intermountain Healthcare, Ogden, UT 84403, USA
    J Perinatol 28:24-8. 2008
    ..Modern blood cell analyzers measure the MCV, and calculate the MCHC and MCH, on the basis of logs higher sample sizes than employed in the original methods...
  51. ncbi request reprint Hematological abnormalities during the first week of life among neonates with Down syndrome: data from a multihospital healthcare system
    E Henry
    Department of Women and Newborns, Intermountain Healthcare, Institute for Health Care Delivery Research, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Am J Med Genet A 143:42-50. 2007
    ..Hematological abnormalities were so common in this group that it seems reasonable to recommend that one or more CBCs be obtained on all neonates with Down syndrome...
  52. doi request reprint Attitudes of NICU professionals regarding feeding blood-tinged colostrum or milk
    M M Phelps
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 29:119-23. 2009
    ..We know of no evidence that establishes best practice in this area, and thus we sought to determine attitudes of NICU professionals on which to base a potentially best practice...
  53. doi request reprint Using umbilical cord tissue to detect fetal exposure to illicit drugs: a multicentered study in Utah and New Jersey
    D P Montgomery
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT 84403, USA
    J Perinatol 28:750-3. 2008
    ..We assessed umbilical cord tissue as a means of detecting fetal exposure to five classes of drugs of abuse...
  54. ncbi request reprint Effect of ampicillin on the bleeding time of neonatal intensive care unit patients
    M J Sheffield
    Department of Neonatology, Intermountain Healthcare, McKay Dee Hospital Center, Ogden, UT 84403, USA
    J Perinatol 30:527-30. 2010
    ..Ampicillin is administered commonly to neonatal intensive care unit (NICU) patients, but its effect on bleeding time in this population has not been reported earlier...
  55. ncbi request reprint A phase 1 trial testing an enteral solution patterned after human amniotic fluid to treat feeding intolerance
    Cindy K Barney
    Intermountain Health Care Neonatology Collaborative Research Group, Ogden, Utah, USA
    Adv Neonatal Care 6:89-95. 2006
    ..In these infants, feeding tolerance might improve after oral administration of enterocyte growth factors in a sterile, isotonic, noncaloric solution patterned after human amniotic fluid...
  56. ncbi request reprint Severe Thrombocytopenia in the NICU
    Vickie L Baer
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, Utah 84403, USA
    Pediatrics 124:e1095-100. 2009
    ..Severe thrombocytopenia (platelets <or= 50000/microL) in a NICU patient can have significant consequences; however, previous reports have not focused exclusively on NICU patients with counts this low...
  57. ncbi request reprint The effect of instituting a prehospital-discharge newborn bilirubin screening program in an 18-hospital health system
    Larry D Eggert
    NICU Development Team, Intermountain Health Care, Salt Lake City, Utah, USA
    Pediatrics 117:e855-62. 2006
    ..Data during 2 periods of time, before versus after initiating the program, were compared to assess the effect of the program on significant hyperbilirubinemia and rehospitalization...
  58. ncbi request reprint Implementing feeding guidelines for NICU patients<2000 g results in less variability in nutrition outcomes
    Jennifer L Street
    Intermountain Healthcare Neonatology Research, McKay Dee Hospital Center, Ogden 84403, and Department of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City, USA
    JPEN J Parenter Enteral Nutr 30:515-8. 2006
    ..We then assessed variability in feeding-related outcomes during a period before (period 1) vs after (period 2) implementing these guidelines...
  59. doi request reprint The CBC: reference ranges for neonates
    Robert D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Institute for Healthcare Delivery Research, University of Utah School of Medicine, Salt Lake City, UT, USA
    Semin Perinatol 33:3-11. 2009
    ..The present review brings together several of our recent reports, displaying reference ranges for elements of the CBC among neonates at various gestational and postnatal ages...
  60. ncbi request reprint Causes of hemolysis in neonates with extreme hyperbilirubinemia
    R D Christensen
    Women and Newborn s Clinical Program, Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 34:616-9. 2014
    ..We instituted a quality improvement process to enhance our capacity to diagnose genetic hemolytic conditions in neonates with extreme hyperbilirubinemia...
  61. doi request reprint A neonate with Coombs-negative hemolytic jaundice with spherocytes but normal erythrocyte indices: a rare case of autosomal-recessive hereditary spherocytosis due to alpha-spectrin deficiency
    H M Yaish
    Division of Hematology Oncology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA
    J Perinatol 33:404-6. 2013
    ....
  62. ncbi request reprint Neonatal outcomes following a tight nuchal cord
    E Henry
    Institute for Healthcare Delivery Research, Salt Lake City, UT, USA
    J Perinatol 33:231-4. 2013
    ..As a step toward this, we compared the outcomes of neonates born after a tight nuchal cord vs those born after a loose nuchal cord vs those born after no nuchal cord...
  63. doi request reprint Evaluating neonatal hyperbilirubinemia in late preterm Hispanic twins led to the diagnosis of hereditary spherocytosis in them, and in their sibling and in their mother
    M J Sheffield
    Women and Newborns Clinical Program, Intermountain Healthcare, Salt Lake City, UT 84403, USA
    J Perinatol 31:625-7. 2011
    ..These cases are consistent with our earlier report, which identified an MCHC cutoff of >36 as suggestive of further evaluation for HS...
  64. doi request reprint Very high users of platelet transfusions in the neonatal intensive care unit
    M Lynn Dohner
    Department of Women and Newborns, Intermountain Healthcare, Ogden, Utah 84403, USA
    Transfusion 49:869-72. 2009
    ..To accomplish this, records of all NICU patients in a multihospital health care system who, during a recent 5(1/2)-year period, received 20 or more PLT transfusions were examined...
  65. ncbi request reprint Randomized, controlled trial of slow versus rapid feeding volume advancement in preterm infants
    Robert D Christensen
    Neonatology Research, Intermountain Health Care, Salt Lake City, UT 84111, USA
    J Pediatr 146:710-1. 2005
  66. doi request reprint Estimating the nucleated red blood cell 'emergence time' in neonates
    R D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT, USA
    J Perinatol 34:116-9. 2014
    ..In this study, we estimated the latter as the time required for NRBC to appear in the blood after administering a dose of recombinant EPO...
  67. ncbi request reprint Pattern of daily weights among low birth weight neonates in the neonatal intensive care unit: data from a multihospital health-care system
    R D Christensen
    Intermountain Health Care Clinical Research, and the Institute for Health Care Delivery Research, Salt Lake City, UT, USA
    J Perinatol 26:37-43. 2006
    ....
  68. ncbi request reprint Enteral administration of a simulated amniotic fluid to very low birth weight neonates
    Robert D Christensen
    The Intermountain Health Care Neonatology Collaborative Research Group, Ogden, UT 84403, USA
    J Perinatol 25:380-5. 2005
    ..To reduce feeding intolerance among very low birth weight neonates...
  69. doi request reprint Testing platelet mass versus platelet count to guide platelet transfusions in the neonatal intensive care unit
    Erick Gerday
    Department of Women and Newborns, Intermountain Healthcare, Division of Pediatric Pathology, Primary Children s Medical Center, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Transfusion 49:2034-9. 2009
    ....
  70. doi request reprint Reference ranges for hematocrit and blood hemoglobin concentration during the neonatal period: data from a multihospital health care system
    Jeffery Jopling
    Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, Utah, USA
    Pediatrics 123:e333-7. 2009
    ..Reference ranges for the hematocrit and the blood hemoglobin concentration of newborn infants have previously been reported from relatively small sample sizes by using measurement methods that now are considered outmoded...
  71. ncbi request reprint Single-dose darbepoetin administration to anemic preterm neonates
    Teresa L Warwood
    Intermountain Health Care, Neonatology Clinical Research Group, McKay Dee Hospital, Ogden, UT 84403, USA
    J Perinatol 25:725-30. 2005
    ..In certain situations, preterm neonates might benefit from rEpo, and for such patients darbepoetin would require fewer doses at a lower cost. However, the proper dose and dosing interval have not been established...
  72. ncbi request reprint Effects of instituting the "BEST Program" (Breast Milk Early Saves Trouble) in a level III NICU
    Dianne Montgomery
    McKay Dee Hospital, Ogden, Utah 84403, USA
    J Hum Lact 24:248-51. 2008
    ..001), and a trend was seen in more mothers who initially wanted to bottle-feed but subsequently changed to breastfeeding (P=.08). A trend was also seen in more infants discharged home breastfeeding (P=.09)...
  73. ncbi request reprint In-hospital falls of newborn infants: data from a multihospital health care system
    Sherry A Monson
    Department of Women and Newborns, Intermountain Healthcare, Ogden, Utah 84403, USA
    Pediatrics 122:e277-80. 2008
    ..We sought to analyze the circumstances surrounding all such falls that occurred in an 18-hospital health care system during a 3-year period...
  74. ncbi request reprint Fatal bowel necrosis in two polycytemic term neonates
    Robert D Christensen
    Department of Women and Newborns, Intermountain Healthcare, Ogden and Provo, Utah, USA
    Fetal Pediatr Pathol 27:41-4. 2008
    ..Both required laparotomy, after which the surgeons stated that the entire bowel appeared nonviable. Both had been fed formula exclusively and both received full feedings (> or = 160 mL/kg/day) by 72 hr after birth...
  75. doi request reprint Lansoprazole, ranitidine, and metoclopramide: comparison of practice patterns at 4 level III NICUs within one healthcare system
    Cindy K Barney
    Intermountain Healthcare, McKay Dee Hospital Center, Ogden, Utah 84403, USA
    Adv Neonatal Care 9:129-31. 2009
    ..As a step toward that goal, we conducted a historic cohort analysis of all patients who received any of these medications in 4 Intermountain Healthcare NICUs during the year 2006...
  76. ncbi request reprint Hematopoietic growth factors in neonatal medicine: the use of enterally administered hematopoietic growth factors in the neonatal intensive care unit
    Darlene A Calhoun
    Department of Pediatrics, Division of Neonatology, University of South Florida College of Medicine and All Children s Hospital, Children s Research Institute, 140 7th Avenue South CRI 2006, St Petersburg, FL 33701, USA
    Clin Perinatol 31:169-82. 2004
    ..This article reviews advances in administering synthetic amniotic fluid-like solutions in the NICU...
  77. ncbi request reprint Persistent perianal abscess in early infancy as a presentation of autoimmune neutropenia
    Marisa Lejkowski
    Department of Pediatrics, University of South Florida College of Medicine and All Children s Hospital, St Petersburg, FL 31020, USA
    J Perinatol 23:428-30. 2003
    ..We report two infants with autoimmune neutropenia who presented with a persistent perianal abscess, which has not been documented previously in this population...
  78. ncbi request reprint Tolerance of simulated amniotic fluid in premature neonates
    Sandra E Sullivan
    Division of Neonatology, University of Florida, Gainesville, FL, USA
    Ann Pharmacother 36:1518-24. 2002
    ..To assess the tolerance of simulated amniotic fluid enterally administered in premature neonates...
  79. ncbi request reprint Multicenter analysis of platelet transfusion usage among neonates on extracorporeal membrane oxygenation
    Srinivas C Chevuru
    Department of Pediatrics, University of Florida, Gainesville, Florida, USA
    Pediatrics 109:e89. 2002
    ....
  80. ncbi request reprint Absorption of enteral recombinant human erythropoietin by neonates
    Sandra E Juul
    Department of Pediatrics, Division of Neonatology, University of Washington, Seattle, WA 98195 6320, USA
    Ann Pharmacother 37:782-6. 2003
    ..One possible function of ingested EPO might be to stimulate erythropoiesis. However, it is unclear whether human neonates absorb recombinant human erythropoietin (rhEPO) after oral administration...
  81. ncbi request reprint Effect of beginning recombinant erythropoietin treatment within the first week of life, among very-low-birth-weight neonates, on "early" and "late" erythrocyte transfusions: a meta-analysis
    Anne C Kotto-Kome
    Division of Neonatology, Department of Pediatrics, University of South Florida College of Medicine and All Children s Hospital, St Petersburg, FL 33772, USA
    J Perinatol 24:24-9. 2004
    ....
  82. ncbi request reprint Effect of recombinant erythropoietin on "late" transfusions in the neonatal intensive care unit: a meta-analysis
    Maria G Garcia
    The National Institute of Perinatology, Mexico City, Mexico
    J Perinatol 22:108-11. 2002
    ....
  83. ncbi request reprint The concentration of circulating megakaryocyte progenitors in preterm neonates is a function of post-conceptional age
    Matthew A Saxonhouse
    Division of Neonatology, Department of Pediatrics, University of Florida, College of Medicine, P O Box 100296, Gainesville, FL 32610 0296, USA
    Early Hum Dev 78:119-24. 2004
    ..We found an inverse relationship between concentration of circulating Mk progenitors and post-conceptional age (r=-0.54, p=0.0002)...
  84. ncbi request reprint A neonate with severe thrombocytopenia and radio-ulnar synostosis
    Martha C Sola
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    J Perinatol 24:528-30. 2004
    ..This entity can be distinguished from the TAR syndrome (thrombocytopenia and absent radii) by the distinctive orthopedic issues, different underlying genetic mutations, and a more worrisome prognosis for CAMT than for TAR...
  85. ncbi request reprint Severe thrombocytopenia in a neonate with congenital HIV infection
    Patrick Tighe
    Department of Pediatrics, University of Florida, Gainesville 32610, USA
    J Pediatr 146:408-13. 2005
  86. ncbi request reprint Pseudothrombocytopenia in a preterm neonate
    Robert D Christensen
    Division of Neonatology, Department of Pediatrics, University of South Florida College of Medicine and All Children s Hospital, St Petersburg, Florida, USA
    Pediatrics 114:273-5. 2004
    ....
  87. ncbi request reprint Benign B-cell precursors (hematogones) are the predominant lymphoid population in the bone marrow of preterm infants
    Lisa M Rimsza
    Department of Pathology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA
    Biol Neonate 86:247-53. 2004
    ..These findings are pertinent for the interpretation of BM and peripheral blood samples in this age group as survival improves and diagnostic samples become more common...
  88. ncbi request reprint Developmental changes in the expression of transcription factors GATA-1, -2 and -3 during the onset of human medullary haematopoiesis
    Christof Dame
    Department of Pediatrics, University of Florida, Gainesville 32610 0296, USA
    Br J Haematol 119:510-5. 2002
    ....
  89. ncbi request reprint Reticulated platelet percentages in term and preterm neonates
    Matthew A Saxonhouse
    Division of Neonatology, Department of Pediatrics, University of Florida College of Medicine, P O Box 100296, Gainesville, FL 32610 0296, USA
    J Pediatr Hematol Oncol 26:797-802. 2004
    ..The authors aimed to determine whether their reticulated platelet percentage (RP%) analysis technique was suitable for use in term and preterm neonates and to characterize RP% values among nonthrombocytopenic neonates...
  90. ncbi request reprint Megakaryocyte size and concentration in the bone marrow of thrombocytopenic and nonthrombocytopenic neonates
    Martha C Sola-Visner
    Department of Pediatrics, University of Florida, Gainesville, FL 32611, USA
    Pediatr Res 61:479-84. 2007
    ..001). This was not observed among thrombocytopenic neonates, suggesting a developmental limitation in their ability to increase megakaryocyte size...
  91. ncbi request reprint Immune neutropenia in the neonate
    Akhil Maheshwari
    Department of Pediatrics, University of South Florida College of Medicine and All Children s Hospital, St Petersburg, USA
    Adv Pediatr 49:317-39. 2002
    ..A review of these disorders is presented, with basic information on the neutrophil antigen systems, pathophysiologic mechanisms, laboratory diagnosis, and therapeutic options...
  92. ncbi request reprint Evidence that the granulocyte colony-stimulating factor (G-CSF) receptor plays a role in the pharmacokinetics of G-CSF and PegG-CSF using a G-CSF-R KO model
    Anne C Kotto-Kome
    All Children s Hospital, Children s Research Institute, University of South Florida, 140 Seventh Avenue South CRI Room 2006, St Petersburg, FL 33701, USA
    Pharmacol Res 50:55-8. 2004
    ..In both WT and KO mice, increasing the dose of figrastim or pegfilgrastim resulted in a proportional increase in the AUC. A functional G-CSF-R is an important mechanism in the plasma clearance of both filgrastim and pegfilgrastim...
  93. ncbi request reprint Circulating concentrations of chemokines in cord blood, neonates, and adults
    Sandra E Sullivan
    Division of Neonatology, University of Florida College of Medicine, Gainesville, Florida 32610 0296, USA
    Pediatr Res 51:653-7. 2002
    ..We conclude that the chemotactic defect observed in premature neonates is not the result of diminished circulating concentrations of any of the specific chemokines we measured...
  94. ncbi request reprint Resistance to recombinant human granulocyte colony-stimulating factor in neonatal alloimmune neutropenia associated with anti-human neutrophil antigen-2a (NB1) antibodies
    Akhil Maheshwari
    Division of Neonatology, Department of Pediatrics, University of South Florida College of Medicine and All Children s Hospital, St Petersburg, Florida 33701, USA
    Pediatrics 109:e64. 2002
    ....
  95. ncbi request reprint Recombinant granulocyte colony-stimulating factor administered enterally to neonates is not absorbed
    Darlene A Calhoun
    Division of Neonatology, Department of Pediatrics, University of South Florida College of Medicine, All Children s Hospital, St Petersburg, FL 33710, USA
    Pediatrics 112:421-3. 2003
    ..On this basis, we conclude that orally administered rhG-CSF is not absorbed in significant quantities, and we speculate that the G-CSF swallowed by the fetus and neonate has local but not systemic effects...
  96. ncbi request reprint Effects of interleukin-8 on the developing human intestine
    Akhil Maheshwari
    Division of Neonatology, Department of Pediatrics, University of South Florida College of Medicine, Tampa, FL, USA
    Cytokine 20:256-67. 2002
    ..IL-8 also protects intestinal cells against chemical injury. These results suggest that besides its better-known role as a neutrophil chemoattractant, IL-8 has a trophic function in the developing human intestine...
  97. ncbi request reprint Tolerance of an enterally administered simulated amniotic fluid-like solution by neonates recovering from surgery for congenital bowel abnormalities
    Victoria Lima-Rogel
    Division of Neonatology Hospital General Dr Ignacio Morones Prieto, Univesidad Autónoma de San Luis Potosi City, San Luis Potosi, Mexico
    J Perinatol 24:295-8. 2004
    ..The overall hypothesis was that the trophic effect of the solution on intestinal villi would facilitate advancement to full enteral feedings. The specific hypothesis tested in this pilot trial was that the solution would be tolerated...
  98. ncbi request reprint Effects of hypoxia on megakaryocyte progenitors obtained from the umbilical cord blood of term and preterm neonates
    Matthew A Saxonhouse
    Department of Pediatrics, University of Florida, Gainesville, 32610 0296, USA
    Biol Neonate 89:104-8. 2006
    ..We hypothesized that decreased Mk production is the result of a direct inhibitory effect of hypoxia on the proliferation of Mk progenitors, or a hypoxia-induced change in the fetal hematopoietic environment...
  99. ncbi request reprint Effects of enterally administering granulocyte colony-stimulating factor to suckling mice
    Jason A Gersting
    Department of Pediatrics, University of Florida, Divsion of Neonatology, Gainesville, FL 32610, USA
    Pediatr Res 55:802-6. 2004
    ..We speculate that the G-CSF present in amniotic fluid, colostrum, and milk acts as a topical intestinal growth factor and has little or no granulocytopoietic action...
  100. ncbi request reprint Effect of administering recombinant erythropoietin to women with postpartum anemia: a meta-analysis
    Anne C Kotto-Kome
    Division of Neonatology, Department of Pediatrics, University of South Florida College of Medicine, All Children s Hospital, St Petersburg, FL 33772, USA
    J Perinatol 24:11-5. 2004
    ..However, it is not clear whether such an approach can be supported by evidence and should be generally recommended...
  101. ncbi request reprint Effects of anoxia on megakaryocyte progenitors derived from cord blood CD34pos cells
    Matthew A Saxonhouse
    Department of Pediatrics, University of Florida, Gainesville, FL, USA
    Eur J Haematol 71:359-65. 2003
    ..The thrombocytopenia in some cases is the result of disseminated intravascular coagulation, but that mechanism fails to account for all, perhaps the majority, of cases...