Heinz Ulrich Weier

Summary

Affiliation: Lawrence Berkeley National Laboratory
Country: USA

Publications

  1. ncbi request reprint Assignment of the RNA-specific adenosine deaminase gene (Adar) to mouse chromosome 3F2 by in situ hybridization
    H U Weier
    Life Sciences Division, University of California, Lawrence Berkeley National Laboratory, Berkeley, USA
    Cytogenet Cell Genet 89:214-5. 2000
  2. pmc Somatic genomic variations in extra-embryonic tissues
    Jingly F Weier
    University of California UC, San Francisco, CA, USA
    Curr Genomics 11:402-8. 2010
  3. pmc Validation of DNA probes for molecular cytogenetics by mapping onto immobilized circular DNA
    Karin M Greulich-Bode
    Division Genetics of Skin Carcinogenesis, German Cancer Research Center DKFZ, Heidelberg, Germany
    Mol Cytogenet 1:28. 2008
  4. pmc Kinase expression and chromosomal rearrangements in papillary thyroid cancer tissues: investigations at the molecular and microscopic levels
    H U G Weier
    Life Sciences Division, University of California, E O Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    J Physiol Pharmacol 60:47-55. 2009
  5. ncbi request reprint Applications and technical challenges of fluorescence in situ hybridization in stem cell research
    Heinz Ulli G Weier
    Life Sciences Division 74 157, University of California, E O Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Blood Cells Mol Dis 32:68-76. 2004
  6. ncbi request reprint FISH in cancer diagnosis and prognostication: from cause to course of disease
    Heinz Ulrich G Weier
    Life Sciences Division 74 157, University of California, E O Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Expert Rev Mol Diagn 2:109-19. 2002
  7. ncbi request reprint Towards a full karyotype screening of interphase cells: 'FISH and chip' technology
    H Weier
    Department of Subcellular Structure, Life Sciences Division MS 74 157, University of California, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Mol Cell Endocrinol 183:S41-5. 2001
  8. ncbi request reprint Monitoring signal transduction in cancer: tyrosine kinase gene expression profiling
    H U Weier
    Life Sciences Division, E O Lawrence Berkeley National Laboratory, University of California, 1 Cyclotron Road, MS 74 157, Berkeley, CA 94720, USA
    J Histochem Cytochem 49:673-4. 2001
  9. ncbi request reprint Aneuploidy involving chromosome 1 in failed-fertilized human oocytes is unrelated to maternal age
    Jingly Fung Weier
    Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California, San Francisco, USA
    J Assist Reprod Genet 22:285-93. 2005
  10. ncbi request reprint Human cytotrophoblasts acquire aneuploidies as they differentiate to an invasive phenotype
    Jingly F Weier
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA 94143 0720, USA
    Dev Biol 279:420-32. 2005

Research Grants

  1. RADIATION-INDUCED THYROID CANCER
    Heinz Ulrich G Weier; Fiscal Year: 2010
  2. RADIATION INDUCED THYROID CANCER
    Heinz Ulrich Weier; Fiscal Year: 2000
  3. RADIATION-INDUCED THYROID CANCER
    Heinz Ulrich Weier; Fiscal Year: 2009
  4. BAC-FISH Assays for Sensitive Karyotyping of Cancer Cells
    Heinz Ulrich Weier; Fiscal Year: 2007
  5. Aneuploid Cells in the Human Placenta
    Heinz Ulrich Weier; Fiscal Year: 2006
  6. Aneuploid Cells in the Human Placenta
    Heinz Ulrich Weier; Fiscal Year: 2005
  7. Aneuploid Cells in the Human Placenta
    Heinz Ulrich Weier; Fiscal Year: 2004
  8. RADIATION INDUCED THYROID CANCER
    Heinz Ulrich Weier; Fiscal Year: 2002
  9. RADIATION INDUCED THYROID CANCER
    Heinz Ulrich Weier; Fiscal Year: 2001

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Assignment of the RNA-specific adenosine deaminase gene (Adar) to mouse chromosome 3F2 by in situ hybridization
    H U Weier
    Life Sciences Division, University of California, Lawrence Berkeley National Laboratory, Berkeley, USA
    Cytogenet Cell Genet 89:214-5. 2000
  2. pmc Somatic genomic variations in extra-embryonic tissues
    Jingly F Weier
    University of California UC, San Francisco, CA, USA
    Curr Genomics 11:402-8. 2010
    ..Thus, under the special circumstances of human reproduction, somatic genomic variations may exert a beneficial, anti-neoplastic effect on the organism...
  3. pmc Validation of DNA probes for molecular cytogenetics by mapping onto immobilized circular DNA
    Karin M Greulich-Bode
    Division Genetics of Skin Carcinogenesis, German Cancer Research Center DKFZ, Heidelberg, Germany
    Mol Cytogenet 1:28. 2008
    ..However, when developing probes for the quantitative analysis of rearrangements involving genomic intervals of less than 100 kb, careful probe selection and characterization are of paramount importance...
  4. pmc Kinase expression and chromosomal rearrangements in papillary thyroid cancer tissues: investigations at the molecular and microscopic levels
    H U G Weier
    Life Sciences Division, University of California, E O Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    J Physiol Pharmacol 60:47-55. 2009
    ..Knowledge of the kind of genetic alterations may facilitate the early detection and staging of chPTC as well as provide guidance for therapeutic intervention...
  5. ncbi request reprint Applications and technical challenges of fluorescence in situ hybridization in stem cell research
    Heinz Ulli G Weier
    Life Sciences Division 74 157, University of California, E O Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Blood Cells Mol Dis 32:68-76. 2004
    ..This report summarizes our technical achievements relevant to stem cell research and outlines plans for future research and developments...
  6. ncbi request reprint FISH in cancer diagnosis and prognostication: from cause to course of disease
    Heinz Ulrich G Weier
    Life Sciences Division 74 157, University of California, E O Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Expert Rev Mol Diagn 2:109-19. 2002
    ..This information provides disease-specific information to the attending physician and should enable the design of patient-specific protocols for disease intervention...
  7. ncbi request reprint Towards a full karyotype screening of interphase cells: 'FISH and chip' technology
    H Weier
    Department of Subcellular Structure, Life Sciences Division MS 74 157, University of California, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Mol Cell Endocrinol 183:S41-5. 2001
    ..Finally, DNA micro-arrays are under development to score all of the human chromosomes in a single experiment and to increase the resolution with which micro-deletions can be delineated...
  8. ncbi request reprint Monitoring signal transduction in cancer: tyrosine kinase gene expression profiling
    H U Weier
    Life Sciences Division, E O Lawrence Berkeley National Laboratory, University of California, 1 Cyclotron Road, MS 74 157, Berkeley, CA 94720, USA
    J Histochem Cytochem 49:673-4. 2001
    ..Examples demonstrate how this innovative assay might help to define new markers for tumor progression and potential targets for disease intervention. (J Histochem Cytochem 49:673-674, 2001)..
  9. ncbi request reprint Aneuploidy involving chromosome 1 in failed-fertilized human oocytes is unrelated to maternal age
    Jingly Fung Weier
    Department of Obstetrics, Gynecology, and Reproductive Sciences, School of Medicine, University of California, San Francisco, USA
    J Assist Reprod Genet 22:285-93. 2005
    ..To study whether maternal meiotic errors in failed-fertilized oocytes involving chromosome 1 occur at frequencies similar to those involving other autosomes, and whether their frequency is affected by maternal age...
  10. ncbi request reprint Human cytotrophoblasts acquire aneuploidies as they differentiate to an invasive phenotype
    Jingly F Weier
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA 94143 0720, USA
    Dev Biol 279:420-32. 2005
    ..Thus, aneuploidy appears to be an important component of normal placentation, perhaps limiting the proliferative and invasive potential of cytotrophoblasts within the uterus...
  11. ncbi request reprint Quantitative DNA fiber mapping in genome research and construction of physical maps
    Heinz Ulrich G Weier
    Department of Genome Biology, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
    Methods Mol Biol 338:31-57. 2006
    ....
  12. pmc Chromosome-specific DNA repeat probes
    Adolf Baumgartner
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California, CA 94720, USA
    J Histochem Cytochem 54:1363-70. 2006
    ....
  13. pmc Independence of replisomes in Escherichia coli chromosomal replication
    Adam M Breier
    Graduate Group in Biophysics and Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 102:3942-7. 2005
    ..We suggest an improved version of the factory model that retains the advantages of threading DNA through colocalized replisomes at about equal rates, but allows the cell flexibility to overcome obstacles encountered during elongation...

Research Grants11

  1. RADIATION-INDUCED THYROID CANCER
    Heinz Ulrich G Weier; Fiscal Year: 2010
    ..We expect this research to lead to improved control of PTC with regard to early disease detection and better disease management and, thus, to enhance public health services. ..
  2. RADIATION INDUCED THYROID CANCER
    Heinz Ulrich Weier; Fiscal Year: 2000
    ..We will prepare stable cell lines carrying the oncogenic rearrangements for further characterization and distribution. Finally, we will examine the levels and localization of mRNAs with Northern and in situ hybridization analysis. ..
  3. RADIATION-INDUCED THYROID CANCER
    Heinz Ulrich Weier; Fiscal Year: 2009
    ..We expect this research to lead to improved control of PTC with regard to early disease detection and better disease management and, thus, to enhance public health services. ..
  4. BAC-FISH Assays for Sensitive Karyotyping of Cancer Cells
    Heinz Ulrich Weier; Fiscal Year: 2007
    ....
  5. Aneuploid Cells in the Human Placenta
    Heinz Ulrich Weier; Fiscal Year: 2006
    ..We will also have detailed information about the frequency, localization and types of aneuploid cells at the fetal-maternal interface and the effects of aneuploidy on CTB proliferation and HLA-G gene expression. ..
  6. Aneuploid Cells in the Human Placenta
    Heinz Ulrich Weier; Fiscal Year: 2005
    ..We will also have detailed information about the frequency, localization and types of aneuploid cells at the fetal-maternal interface and the effects of aneuploidy on CTB proliferation and HLA-G gene expression. ..
  7. Aneuploid Cells in the Human Placenta
    Heinz Ulrich Weier; Fiscal Year: 2004
    ..We will also have detailed information about the frequency, localization and types of aneuploid cells at the fetal-maternal interface and the effects of aneuploidy on CTB proliferation and HLA-G gene expression. ..
  8. RADIATION INDUCED THYROID CANCER
    Heinz Ulrich Weier; Fiscal Year: 2002
    ..We will prepare stable cell lines carrying the oncogenic rearrangements for further characterization and distribution. Finally, we will examine the levels and localization of mRNAs with Northern and in situ hybridization analysis. ..
  9. RADIATION INDUCED THYROID CANCER
    Heinz Ulrich Weier; Fiscal Year: 2001
    ..We will prepare stable cell lines carrying the oncogenic rearrangements for further characterization and distribution. Finally, we will examine the levels and localization of mRNAs with Northern and in situ hybridization analysis. ..