Nicholas J Wang

Summary

Affiliation: Lawrence Berkeley National Laboratory
Country: USA

Publications

  1. pmc High-resolution molecular characterization of 15q11-q13 rearrangements by array comparative genomic hybridization (array CGH) with detection of gene dosage
    Nicholas J Wang
    Department of Human Genetics, University of California Los Angeles, Los Angeles, CA 90095, USA
    Am J Hum Genet 75:267-81. 2004
  2. pmc Autistic disorder associated with a paternally derived unbalanced translocation leading to duplication of chromosome 15pter-q13.2: a case report
    David J Wu
    Department of Biological Sciences, University of Delaware, Newark, USA
    Mol Cytogenet 2:27. 2009
  3. pmc Analysis of molecular inversion probe performance for allele copy number determination
    Yuker Wang
    Affymetrix Inc, Shoreline Blvd, South San Francisco, CA 94080, USA
    Genome Biol 8:R246. 2007
  4. pmc Integrated analysis of breast cancer cell lines reveals unique signaling pathways
    Laura M Heiser
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Genome Biol 10:R31. 2009
  5. pmc A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047
    Wen Lin Kuo
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
    BMC Med 7:77. 2009
  6. pmc Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15
    Nicholas J Wang
    Nemours Biomedical Research, Alfred I, duPont Hospital for Children, Wilmington, Delaware, 19803, USA
    BMC Genet 9:2. 2008
  7. ncbi request reprint Atypical breakpoints generating mosaic interstitial duplication and triplication of chromosome 15q11-q13
    Alexander S Parokonny
    Human Genetics Research Laboratory, Nemours Biomedical Research, Wilmington, Delaware 19803, USA
    Am J Med Genet A 143:2473-7. 2007
  8. ncbi request reprint Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin-proteasome pathway processes
    Colin A Baron
    Department of Pathology, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
    Hum Mol Genet 15:853-69. 2006

Collaborators

Detail Information

Publications9

  1. pmc High-resolution molecular characterization of 15q11-q13 rearrangements by array comparative genomic hybridization (array CGH) with detection of gene dosage
    Nicholas J Wang
    Department of Human Genetics, University of California Los Angeles, Los Angeles, CA 90095, USA
    Am J Hum Genet 75:267-81. 2004
    ..These results indicate that array CGH is a powerful technique to study rearrangements of proximal chromosome 15q...
  2. pmc Autistic disorder associated with a paternally derived unbalanced translocation leading to duplication of chromosome 15pter-q13.2: a case report
    David J Wu
    Department of Biological Sciences, University of Delaware, Newark, USA
    Mol Cytogenet 2:27. 2009
    ..This case suggests that biallelically expressed genes on proximal 15q contribute to the idic(15) autism phenotype...
  3. pmc Analysis of molecular inversion probe performance for allele copy number determination
    Yuker Wang
    Affymetrix Inc, Shoreline Blvd, South San Francisco, CA 94080, USA
    Genome Biol 8:R246. 2007
    ....
  4. pmc Integrated analysis of breast cancer cell lines reveals unique signaling pathways
    Laura M Heiser
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Genome Biol 10:R31. 2009
    ..Deregulation in signaling along the EgfR-MAPK pathway is common in breast cancer, though the manner in which deregulation occurs varies between both individuals and cancer subtypes...
  5. pmc A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047
    Wen Lin Kuo
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
    BMC Med 7:77. 2009
    ....
  6. pmc Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15
    Nicholas J Wang
    Nemours Biomedical Research, Alfred I, duPont Hospital for Children, Wilmington, Delaware, 19803, USA
    BMC Genet 9:2. 2008
    ..Five recurrent breakpoints have been described in most cases of segmental aneuploidy of chromosome 15q11-q13 and previous studies have shown that most idic(15) chromosomes arise through BP3:BP3 or BP4:BP5 recombination events...
  7. ncbi request reprint Atypical breakpoints generating mosaic interstitial duplication and triplication of chromosome 15q11-q13
    Alexander S Parokonny
    Human Genetics Research Laboratory, Nemours Biomedical Research, Wilmington, Delaware 19803, USA
    Am J Med Genet A 143:2473-7. 2007
  8. ncbi request reprint Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin-proteasome pathway processes
    Colin A Baron
    Department of Pathology, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
    Hum Mol Genet 15:853-69. 2006
    ..This study provides insight into the direct and indirect effects of copy number gains in chromosome 15 and provides a framework for the study of these effects in neuronal systems...