Affiliation: Lawrence Livermore National Laboratory
- Ovcharenko I, Loots G, Nobrega M, Hardison R, Miller W, Stubbs L. Evolution and functional classification of vertebrate gene deserts. Genome Res. 2005;15:137-45 pubmed..Stable gene deserts resist chromosomal rearrangements and appear to harbor multiple distant regulatory elements physically linked to their neighboring genes, with the linearity of conservation invariant throughout vertebrate evolution. ..
- Ovcharenko I, Stubbs L, Loots G. Interpreting mammalian evolution using Fugu genome comparisons. Genomics. 2004;84:890-5 pubmed..This newly defined threshold identifies 90% of all human/Fugu noncoding ECRs without the assistance of human-Fugu genome alignments and provides a very efficient filter for identifying functional human/mouse ECRs. ..