CYNTHIA THERESE MCMURRAY

Summary

Affiliation: Lawrence Berkeley National Laboratory
Country: USA

Publications

  1. ncbi Mechanisms of trinucleotide repeat instability during human development
    Cynthia T McMurray
    Lawrence Berkeley National Laboratory, Life Sciences Division, 1 Cyclotron Rd, 83R0101, Berkeley, California 94720, USA
    Nat Rev Genet 11:786-99. 2010
  2. ncbi Resolving brain regions using nanostructure initiator mass spectrometry imaging of phospholipids
    Do Yup Lee
    Lawrence Berkeley Laboratories, Life Sciences Division, 1 Cyclotron Rd, Berkeley, CA 94720, USA
    Integr Biol (Camb) 4:693-9. 2012

Research Grants

  1. Mismatch Repair and DNA expansion
    CYNTHIA THERESE MCMURRAY; Fiscal Year: 2010
  2. Chemical Fingerprinting
    CYNTHIA THERESE MCMURRAY; Fiscal Year: 2010
  3. Age of Onset and Huntingtons Disease
    CYNTHIA THERESE MCMURRAY; Fiscal Year: 2010
  4. Mismatch Repair and DNA expansion
    CYNTHIA THERESE MCMURRAY; Fiscal Year: 2010

Collaborators

  • Do Yup Lee
  • Ben Bowen
  • KATHERINE LOUIE
  • Christie A Canaria
  • Trent Northen
  • Virginia Platt

Detail Information

Publications2

  1. ncbi Mechanisms of trinucleotide repeat instability during human development
    Cynthia T McMurray
    Lawrence Berkeley National Laboratory, Life Sciences Division, 1 Cyclotron Rd, 83R0101, Berkeley, California 94720, USA
    Nat Rev Genet 11:786-99. 2010
    ..We need now to connect the dots among human genetics, pathway biochemistry and the appropriate model systems to understand the mechanism of expansion as it occurs in human disease...
  2. ncbi Resolving brain regions using nanostructure initiator mass spectrometry imaging of phospholipids
    Do Yup Lee
    Lawrence Berkeley Laboratories, Life Sciences Division, 1 Cyclotron Rd, Berkeley, CA 94720, USA
    Integr Biol (Camb) 4:693-9. 2012
    ..This method accurately distinguished the frontal (or somatomotor) and dorsal (or retrosplenial) regions of the cortex from each other and from the pons region...

Research Grants4

  1. Mismatch Repair and DNA expansion
    CYNTHIA THERESE MCMURRAY; Fiscal Year: 2010
    ..These studies will not only provide insights into how mutations in the mismatch repair genes cause expansion and disease, but will also broaden our conceptual framework for DNA damage recognition. ..
  2. Chemical Fingerprinting
    CYNTHIA THERESE MCMURRAY; Fiscal Year: 2010
    ..Inhibitors selected by the conventional methods are predicted to overlap with those identified from the global screen. ..
  3. Age of Onset and Huntingtons Disease
    CYNTHIA THERESE MCMURRAY; Fiscal Year: 2010
    ..In a reverse approach, we will reduce biomarker production in HD150KI mice by treatment with anti-oxidants, and test whether somatic expansion is also reduced. ..
  4. Mismatch Repair and DNA expansion
    CYNTHIA THERESE MCMURRAY; Fiscal Year: 2010
    ..These studies will not only provide insights into how mutations in the mismatch repair genes cause expansion and disease, but will also broaden our conceptual framework for DNA damage recognition. ..