Ted A Laurence

Summary

Affiliation: Lawrence Livermore National Laboratory
Country: USA

Publications

  1. ncbi request reprint Analytical chemistry. How to detect weak pairs
    Ted A Laurence
    Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA
    Science 299:667-8. 2003
  2. doi request reprint Robust SERS enhancement factor statistics using rotational correlation spectroscopy
    Ted A Laurence
    Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States
    Nano Lett 12:2912-7. 2012
  3. doi request reprint Extracting the distribution of laser damage precursors on fused silica surfaces for 351 nm, 3 ns laser pulses at high fluences (20-150 J/cm2)
    Ted A Laurence
    Physical and Life Sciences Directorate and National Ignition Facility, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
    Opt Express 20:11561-73. 2012
  4. pmc Correlation spectroscopy of minor fluorescent species: signal purification and distribution analysis
    Ted A Laurence
    Chemistry, Materials, and Life Sciences, Lawrence Livermore National Laboratory, Livermore, California, USA
    Biophys J 92:2184-98. 2007
  5. pmc Probing structural heterogeneities and fluctuations of nucleic acids and denatured proteins
    Ted A Laurence
    Physical Biosciences Institute, Lawrence Livermore National Laboratory, Livermore, CA 94550, USA
    Proc Natl Acad Sci U S A 102:17348-53. 2005
  6. ncbi request reprint Fast, flexible algorithm for calculating photon correlations
    Ted A Laurence
    Physical Biosciences Institute, Chemistry and Materials Science Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
    Opt Lett 31:829-31. 2006
  7. pmc Motion of a DNA sliding clamp observed by single molecule fluorescence spectroscopy
    Ted A Laurence
    Lawrence Livermore National Laboratory, California 94550, USA
    J Biol Chem 283:22895-906. 2008
  8. pmc Stoichiometry of reconstituted high-density lipoproteins in the hydrated state determined by photon antibunching
    Sonny Ly
    Physical and Life Science Directorate, Lawrence Livermore National Laboratory, Livermore, California, USA
    Biophys J 101:970-5. 2011
  9. pmc Binding of apolipoprotein E inhibits the oligomer growth of amyloid-β peptide in solution as determined by fluorescence cross-correlation spectroscopy
    Sonny Ly
    Physical and Life Science Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
    J Biol Chem 288:11628-35. 2013
  10. doi request reprint Rapid, solution-based characterization of optimized SERS nanoparticle substrates
    Ted A Laurence
    Chemistry, Materials, Earth and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
    J Am Chem Soc 131:162-9. 2009

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Analytical chemistry. How to detect weak pairs
    Ted A Laurence
    Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA
    Science 299:667-8. 2003
  2. doi request reprint Robust SERS enhancement factor statistics using rotational correlation spectroscopy
    Ted A Laurence
    Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States
    Nano Lett 12:2912-7. 2012
    ..This significant statistical sampling shows that very high SERS enhancement factors can be obtained on a consistent basis using nanoparticle linking...
  3. doi request reprint Extracting the distribution of laser damage precursors on fused silica surfaces for 351 nm, 3 ns laser pulses at high fluences (20-150 J/cm2)
    Ted A Laurence
    Physical and Life Sciences Directorate and National Ignition Facility, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
    Opt Express 20:11561-73. 2012
    ....
  4. pmc Correlation spectroscopy of minor fluorescent species: signal purification and distribution analysis
    Ted A Laurence
    Chemistry, Materials, and Life Sciences, Lawrence Livermore National Laboratory, Livermore, California, USA
    Biophys J 92:2184-98. 2007
    ..By monitoring the detachment of weakly-bound 30-mer DNA oligomers from a single-stranded DNA plasmid, we show that single-molecule FCS can distinguish between bursts from species that differ by a factor of 5 in diffusion constant...
  5. pmc Probing structural heterogeneities and fluctuations of nucleic acids and denatured proteins
    Ted A Laurence
    Physical Biosciences Institute, Lawrence Livermore National Laboratory, Livermore, CA 94550, USA
    Proc Natl Acad Sci U S A 102:17348-53. 2005
    ..We propose that the larger fluctuations may indicate transient residual structure in the unfolded state...
  6. ncbi request reprint Fast, flexible algorithm for calculating photon correlations
    Ted A Laurence
    Physical Biosciences Institute, Chemistry and Materials Science Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
    Opt Lett 31:829-31. 2006
    ..Execution speed is comparable to the commonly used multiple-tau correlation technique. Wide bin spacings are possible that allow for real-time software calculation of correlations, even for high count rates...
  7. pmc Motion of a DNA sliding clamp observed by single molecule fluorescence spectroscopy
    Ted A Laurence
    Lawrence Livermore National Laboratory, California 94550, USA
    J Biol Chem 283:22895-906. 2008
    ..These results may imply that the clamp not only acts to hold the polymerase on the DNA but also prevents excessive drifting along the DNA...
  8. pmc Stoichiometry of reconstituted high-density lipoproteins in the hydrated state determined by photon antibunching
    Sonny Ly
    Physical and Life Science Directorate, Lawrence Livermore National Laboratory, Livermore, California, USA
    Biophys J 101:970-5. 2011
    ..Both the photon antibunching and photon-counting analyses show that reconstituted high-density lipoprotein particles contain two apo A-I molecules, which is in agreement with the commonly accepted double-belt model...
  9. pmc Binding of apolipoprotein E inhibits the oligomer growth of amyloid-β peptide in solution as determined by fluorescence cross-correlation spectroscopy
    Sonny Ly
    Physical and Life Science Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
    J Biol Chem 288:11628-35. 2013
    ....
  10. doi request reprint Rapid, solution-based characterization of optimized SERS nanoparticle substrates
    Ted A Laurence
    Chemistry, Materials, Earth and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
    J Am Chem Soc 131:162-9. 2009
    ....
  11. ncbi request reprint Quantifying Interactions of a Membrane Protein Embedded in a Lipid Nanodisc using Fluorescence Correlation Spectroscopy
    Sonny Ly
    Lawrence Livermore National Laboratory, Livermore, California
    Biophys J 106:L05-8. 2014
    ..Straightforward sample preparation, acquisition, and analysis procedures make this combined technology attractive for accurately measuring binding kinetics for this important class of protein-protein interactions. ..
  12. pmc Shot-noise limited single-molecule FRET histograms: comparison between theory and experiments
    Eyal Nir
    Department of Chemistry and Biochemistry, and California NanoScience Institute, University of California at Los Angeles, Los Angeles, California 90095, USA
    J Phys Chem B 110:22103-24. 2006
    ..6 A. Finally, we briefly mention the results of a future publication and illustrate them with a simple two-state model system (DNA hairpin), for which the kinetic transition rates between the open and closed conformations are extracted...
  13. ncbi request reprint Alternating-laser excitation of single molecules
    Achillefs N Kapanidis
    Department of Chemistry and Biochemistry, University of California, Los Angeles, 607 Charles E Young Drive East, Los Angeles, California 90095 1569, USA
    Acc Chem Res 38:523-33. 2005
    ..The principle of alternation is compatible with several time scales, allowing monitoring of fast dynamics or simultaneous monitoring of a large number of individual molecules...
  14. pmc Fluorescence-aided molecule sorting: analysis of structure and interactions by alternating-laser excitation of single molecules
    Achillefs N Kapanidis
    Department of Chemistry and Biochemistry, University of California, 607 Charles E Young Drive East, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 101:8936-41. 2004
    ....
  15. ncbi request reprint Retention of transcription initiation factor sigma70 in transcription elongation: single-molecule analysis
    Achillefs N Kapanidis
    Department of Chemistry and Biochemistry, and California Nanosystems Institute, University of California, Los Angeles, 607 Charles E Young Drive East, Los Angeles, California 90095, USA
    Mol Cell 20:347-56. 2005
    ....