Research Topics
| Ted A LaurenceSummaryAffiliation: Lawrence Livermore National Laboratory Country: USA Publications
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Detail Information
Publications
Analytical chemistry. How to detect weak pairsTed A Laurence
Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, USA
Science 299:667-8. 2003
Robust SERS enhancement factor statistics using rotational correlation spectroscopyTed A Laurence
Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States
Nano Lett 12:2912-7. 2012..This significant statistical sampling shows that very high SERS enhancement factors can be obtained on a consistent basis using nanoparticle linking...- Extracting the distribution of laser damage precursors on fused silica surfaces for 351 nm, 3 ns laser pulses at high fluences (20-150 J/cm2)Ted A Laurence
Physical and Life Sciences Directorate and National Ignition Facility, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
Opt Express 20:11561-73. 2012.... 
Correlation spectroscopy of minor fluorescent species: signal purification and distribution analysisTed A Laurence
Chemistry, Materials, and Life Sciences, Lawrence Livermore National Laboratory, Livermore, California, USA
Biophys J 92:2184-98. 2007..By monitoring the detachment of weakly-bound 30-mer DNA oligomers from a single-stranded DNA plasmid, we show that single-molecule FCS can distinguish between bursts from species that differ by a factor of 5 in diffusion constant...- Probing structural heterogeneities and fluctuations of nucleic acids and denatured proteinsTed A Laurence
Physical Biosciences Institute, Lawrence Livermore National Laboratory, Livermore, CA 94550, USA
Proc Natl Acad Sci U S A 102:17348-53. 2005..We propose that the larger fluctuations may indicate transient residual structure in the unfolded state... - Fast, flexible algorithm for calculating photon correlationsTed A Laurence
Physical Biosciences Institute, Chemistry and Materials Science Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
Opt Lett 31:829-31. 2006..Execution speed is comparable to the commonly used multiple-tau correlation technique. Wide bin spacings are possible that allow for real-time software calculation of correlations, even for high count rates... - Motion of a DNA sliding clamp observed by single molecule fluorescence spectroscopyTed A Laurence
Lawrence Livermore National Laboratory, California 94550, USA
J Biol Chem 283:22895-906. 2008..These results may imply that the clamp not only acts to hold the polymerase on the DNA but also prevents excessive drifting along the DNA... - Stoichiometry of reconstituted high-density lipoproteins in the hydrated state determined by photon antibunchingSonny Ly
Physical and Life Science Directorate, Lawrence Livermore National Laboratory, Livermore, California, USA
Biophys J 101:970-5. 2011..Both the photon antibunching and photon-counting analyses show that reconstituted high-density lipoprotein particles contain two apo A-I molecules, which is in agreement with the commonly accepted double-belt model... - Binding of apolipoprotein E inhibits the oligomer growth of amyloid-β peptide in solution as determined by fluorescence cross-correlation spectroscopySonny Ly
Physical and Life Science Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
J Biol Chem 288:11628-35. 2013.... - Rapid, solution-based characterization of optimized SERS nanoparticle substratesTed A Laurence
Chemistry, Materials, Earth and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
J Am Chem Soc 131:162-9. 2009.... - Quantifying Interactions of a Membrane Protein Embedded in a Lipid Nanodisc using Fluorescence Correlation SpectroscopySonny Ly
Lawrence Livermore National Laboratory, Livermore, California
Biophys J 106:L05-8. 2014..Straightforward sample preparation, acquisition, and analysis procedures make this combined technology attractive for accurately measuring binding kinetics for this important class of protein-protein interactions. .. - Shot-noise limited single-molecule FRET histograms: comparison between theory and experimentsEyal Nir
Department of Chemistry and Biochemistry, and California NanoScience Institute, University of California at Los Angeles, Los Angeles, California 90095, USA
J Phys Chem B 110:22103-24. 2006..6 A. Finally, we briefly mention the results of a future publication and illustrate them with a simple two-state model system (DNA hairpin), for which the kinetic transition rates between the open and closed conformations are extracted... - Alternating-laser excitation of single moleculesAchillefs N Kapanidis
Department of Chemistry and Biochemistry, University of California, Los Angeles, 607 Charles E Young Drive East, Los Angeles, California 90095 1569, USA
Acc Chem Res 38:523-33. 2005..The principle of alternation is compatible with several time scales, allowing monitoring of fast dynamics or simultaneous monitoring of a large number of individual molecules... - Fluorescence-aided molecule sorting: analysis of structure and interactions by alternating-laser excitation of single moleculesAchillefs N Kapanidis
Department of Chemistry and Biochemistry, University of California, 607 Charles E Young Drive East, Los Angeles, CA 90095, USA
Proc Natl Acad Sci U S A 101:8936-41. 2004.... - Retention of transcription initiation factor sigma70 in transcription elongation: single-molecule analysisAchillefs N Kapanidis
Department of Chemistry and Biochemistry, and California Nanosystems Institute, University of California, Los Angeles, 607 Charles E Young Drive East, Los Angeles, California 90095, USA
Mol Cell 20:347-56. 2005....