Uffe Hellsten

Summary

Affiliation: Lawrence Berkeley National Laboratory
Country: USA

Publications

  1. ncbi request reprint The sequence and analysis of duplication-rich human chromosome 16
    Joel Martin
    DOE Joint Genome Institute, 2800 Mitchell Avenue, Walnut Creek, California 94598, USA
    Nature 432:988-94. 2004
  2. ncbi request reprint Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization
    Nicholas H Putnam
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA
    Science 317:86-94. 2007
  3. pmc Accelerated gene evolution and subfunctionalization in the pseudotetraploid frog Xenopus laevis
    Uffe Hellsten
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA
    BMC Biol 5:31. 2007
  4. ncbi request reprint The amphioxus genome and the evolution of the chordate karyotype
    Nicholas H Putnam
    Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA
    Nature 453:1064-71. 2008
  5. pmc The genome of the Western clawed frog Xenopus tropicalis
    Uffe Hellsten
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA
    Science 328:633-6. 2010
  6. pmc A segmental genomic duplication generates a functional intron
    Uffe Hellsten
    DOE Joint Genome Institute, Walnut Creek, California 94598, USA
    Nat Commun 2:454. 2011
  7. pmc Genomic analysis of organismal complexity in the multicellular green alga Volvox carteri
    Simon E Prochnik
    U S Department of Energy, Joint Genome Institute, Walnut Creek, CA 94598, USA
    Science 329:223-6. 2010
  8. pmc Phytozome: a comparative platform for green plant genomics
    David M Goodstein
    US Department of Energy, Joint Genome Institute, Walnut Creek, CA 94598, USA
    Nucleic Acids Res 40:D1178-86. 2012
  9. pmc Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing
    Uffe Hellsten
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598
    Proc Natl Acad Sci U S A 110:19478-82. 2013
  10. doi request reprint The dynamic genome of Hydra
    Jarrod A Chapman
    US Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA
    Nature 464:592-6. 2010

Detail Information

Publications14

  1. ncbi request reprint The sequence and analysis of duplication-rich human chromosome 16
    Joel Martin
    DOE Joint Genome Institute, 2800 Mitchell Avenue, Walnut Creek, California 94598, USA
    Nature 432:988-94. 2004
    ....
  2. ncbi request reprint Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization
    Nicholas H Putnam
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA
    Science 317:86-94. 2007
    ..Analysis of diverse pathways suggests that these gene "inventions" along the lineage leading to animals were likely already well integrated with preexisting eukaryotic genes in the eumetazoan progenitor...
  3. pmc Accelerated gene evolution and subfunctionalization in the pseudotetraploid frog Xenopus laevis
    Uffe Hellsten
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA
    BMC Biol 5:31. 2007
    ....
  4. ncbi request reprint The amphioxus genome and the evolution of the chordate karyotype
    Nicholas H Putnam
    Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA
    Nature 453:1064-71. 2008
    ..These genome-scale events shaped the vertebrate genome and provided additional genetic variation for exploitation during vertebrate evolution...
  5. pmc The genome of the Western clawed frog Xenopus tropicalis
    Uffe Hellsten
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA
    Science 328:633-6. 2010
    ..The genome exhibits substantial shared synteny with human and chicken over major parts of large chromosomes, broken by lineage-specific chromosome fusions and fissions, mainly in the mammalian lineage...
  6. pmc A segmental genomic duplication generates a functional intron
    Uffe Hellsten
    DOE Joint Genome Institute, Walnut Creek, California 94598, USA
    Nat Commun 2:454. 2011
    ..This experiment recapitulates in vivo the birth of an intron that arose in the ancestral jawed vertebrate lineage nearly half-a-billion years ago...
  7. pmc Genomic analysis of organismal complexity in the multicellular green alga Volvox carteri
    Simon E Prochnik
    U S Department of Energy, Joint Genome Institute, Walnut Creek, CA 94598, USA
    Science 329:223-6. 2010
    ..Our analysis shows that increases in organismal complexity can be associated with modifications of lineage-specific proteins rather than large-scale invention of protein-coding capacity...
  8. pmc Phytozome: a comparative platform for green plant genomics
    David M Goodstein
    US Department of Energy, Joint Genome Institute, Walnut Creek, CA 94598, USA
    Nucleic Acids Res 40:D1178-86. 2012
    ....
  9. pmc Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing
    Uffe Hellsten
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598
    Proc Natl Acad Sci U S A 110:19478-82. 2013
    ....
  10. doi request reprint The dynamic genome of Hydra
    Jarrod A Chapman
    US Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA
    Nature 464:592-6. 2010
    ....
  11. ncbi request reprint The DNA sequence and biology of human chromosome 19
    Jane Grimwood
    Stanford Human Genome Center, Department of Genetics, Stanford University School of Medicine, 975 California Avenue, Palo Alto, California 94304, USA
    Nature 428:529-35. 2004
    ....
  12. pmc The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans
    Nicole King
    Department of Molecular and Cell Biology and the Center for Integrative Genomics, University of California, Berkeley, California 94720, USA
    Nature 451:783-8. 2008
    ..The completion of the M. brevicollis genome allows us to reconstruct with increasing resolution the genomic changes that accompanied the origin of metazoans...
  13. ncbi request reprint The DNA sequence and comparative analysis of human chromosome 5
    Jeremy Schmutz
    Stanford Human Genome Center, Department of Genetics, Stanford University School of Medicine, 975 California Ave, Palo Alto, California 94304, USA
    Nature 431:268-74. 2004
    ..These duplications are very recent evolutionary events and probably have a mechanistic role in human physiological variation, as deletions in these regions are the cause of debilitating disorders including spinal muscular atrophy...
  14. ncbi request reprint The Trichoplax genome and the nature of placozoans
    Mansi Srivastava
    Center for Integrative Genomics and Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Nature 454:955-60. 2008
    ....