John Game

Summary

Affiliation: Lawrence Berkeley National Laboratory
Country: USA

Publications

  1. pmc X-ray survival characteristics and genetic analysis for nine Saccharomyces deletion mutants that show altered radiation sensitivity
    John C Game
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Genetics 169:51-63. 2005
  2. pmc The RAD6/BRE1 histone modification pathway in Saccharomyces confers radiation resistance through a RAD51-dependent process that is independent of RAD18
    John C Game
    Life Sciences Division, Lawrence Berkeley National Laboratory, CA 94720, USA
    Genetics 173:1951-68. 2006
  3. pmc Excision of misincorporated ribonucleotides in DNA by RNase H (type 2) and FEN-1 in cell-free extracts
    Bjorn Rydberg
    Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 99:16654-9. 2002
  4. ncbi request reprint Use of a genome-wide approach to identify new genes that control resistance of Saccharomyces cerevisiae to ionizing radiation
    John C Game
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Radiat Res 160:14-24. 2003
  5. ncbi request reprint New genome-wide methods bring more power to yeast as a model organism
    John C Game
    Trends Pharmacol Sci 23:445-7. 2002

Collaborators

Detail Information

Publications5

  1. pmc X-ray survival characteristics and genetic analysis for nine Saccharomyces deletion mutants that show altered radiation sensitivity
    John C Game
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Genetics 169:51-63. 2005
    ..Struhl) in which this residue is replaced by other amino acids are also X-ray sensitive, which confirms that methylation of the lysine-79 residue is required for effective repair of radiation damage...
  2. pmc The RAD6/BRE1 histone modification pathway in Saccharomyces confers radiation resistance through a RAD51-dependent process that is independent of RAD18
    John C Game
    Life Sciences Division, Lawrence Berkeley National Laboratory, CA 94720, USA
    Genetics 173:1951-68. 2006
    ..We conclude that IR resistance conferred by BRE1 and DOT1 is mediated through homologous recombinational repair, not postreplication repair, and confirm findings of a G1 checkpoint role for the RAD6/BRE1/DOT1 pathway...
  3. pmc Excision of misincorporated ribonucleotides in DNA by RNase H (type 2) and FEN-1 in cell-free extracts
    Bjorn Rydberg
    Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 99:16654-9. 2002
    ....
  4. ncbi request reprint Use of a genome-wide approach to identify new genes that control resistance of Saccharomyces cerevisiae to ionizing radiation
    John C Game
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Radiat Res 160:14-24. 2003
    ..Our results emphasize that secondary mutations or deviations from euploidy can be a problem in screening this resource for sensitivity to ionizing radiation...
  5. ncbi request reprint New genome-wide methods bring more power to yeast as a model organism
    John C Game
    Trends Pharmacol Sci 23:445-7. 2002
    ..This significantly increases the power of yeast as a model system for studying human cellular responses to these agents, and for identifying human genes that are important in DNA repair and cancer...