I Dubchak

Summary

Affiliation: Lawrence Berkeley National Laboratory
Country: USA

Publications

  1. pmc Multiple whole genome alignments and novel biomedical applications at the VISTA portal
    Michael Brudno
    Department of Computer Science, Banting and Best Department of Medical Research, University of Toronto, 6 King s College Road, Toronto, ON, Canada M5S 3G4
    Nucleic Acids Res 35:W669-74. 2007
  2. pmc The genome portal of the Department of Energy Joint Genome Institute: 2014 updates
    Henrik Nordberg
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA
    Nucleic Acids Res 42:D26-31. 2014
  3. pmc Whole-Genome rVISTA: a tool to determine enrichment of transcription factor binding sites in gene promoters from transcriptomic data
    Inna Dubchak
    Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Bioinformatics 29:2059-61. 2013
  4. pmc RegTransBase--a database of regulatory sequences and interactions based on literature: a resource for investigating transcriptional regulation in prokaryotes
    Michael J Cipriano
    Department of Microbiology, University of California Davis, Davis, CA 95616, USA
    BMC Genomics 14:213. 2013
  5. pmc Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy
    Joseph Donfack
    Department of Human Genetics, The University of Chicago, Chicago, IL 60637, USA
    Respir Res 6:145. 2005
  6. pmc Reconstruction of regulatory and metabolic pathways in metal-reducing delta-proteobacteria
    Dmitry A Rodionov
    Institute for Information Transmission Problems, Russian Academy of Sciences, Bolshoi Karetny per, 19, Moscow 127994, Russia
    Genome Biol 5:R90. 2004
  7. pmc Extensive parallelism in protein evolution
    Georgii A Bazykin
    Life Sciences Institute and Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109 2216, USA
    Biol Direct 2:20. 2007
  8. pmc Comparative genomic reconstruction of transcriptional networks controlling central metabolism in the Shewanella genus
    Dmitry A Rodionov
    Sanford Burnham Medical Research Institute, La Jolla, California, USA
    BMC Genomics 12:S3. 2011
  9. pmc Short sequence motifs, overrepresented in mammalian conserved non-coding sequences
    Simon Minovitsky
    Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    BMC Genomics 8:378. 2007
  10. pmc SNP-VISTA: an interactive SNP visualization tool
    Nameeta Shah
    Institute for Data Analysis and Visualization, IDAV, Department of Computer Science, University of California, Davis, One ShieldsAve, Davis, CA 95616, USA
    BMC Bioinformatics 6:292. 2005

Detail Information

Publications58

  1. pmc Multiple whole genome alignments and novel biomedical applications at the VISTA portal
    Michael Brudno
    Department of Computer Science, Banting and Best Department of Medical Research, University of Toronto, 6 King s College Road, Toronto, ON, Canada M5S 3G4
    Nucleic Acids Res 35:W669-74. 2007
    ..Here we describe various algorithmic and functional improvements implemented in the VISTA portal over the last 2 years. The VISTA Portal is accessible at http://genome.lbl.gov/vista...
  2. pmc The genome portal of the Department of Energy Joint Genome Institute: 2014 updates
    Henrik Nordberg
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA
    Nucleic Acids Res 42:D26-31. 2014
    ..Here we describe major updates of the Genome Portal in the past 2 years with a specific emphasis on efficient handling of the rapidly growing amount of diverse genomic data accumulated in JGI. ..
  3. pmc Whole-Genome rVISTA: a tool to determine enrichment of transcription factor binding sites in gene promoters from transcriptomic data
    Inna Dubchak
    Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Bioinformatics 29:2059-61. 2013
    ..Results are exported in a BED format for rapid visualization in the UCSC genome browser. Flat files of mapped conserved sites and their genomic coordinates are also available for analysis with stand-alone software...
  4. pmc RegTransBase--a database of regulatory sequences and interactions based on literature: a resource for investigating transcriptional regulation in prokaryotes
    Michael J Cipriano
    Department of Microbiology, University of California Davis, Davis, CA 95616, USA
    BMC Genomics 14:213. 2013
    ..Additionally, confirming computationally inferred regulons by experimental data is critically important...
  5. pmc Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy
    Joseph Donfack
    Department of Human Genetics, The University of Chicago, Chicago, IL 60637, USA
    Respir Res 6:145. 2005
    ..Evolutionarily conserved sequences likely have biological function...
  6. pmc Reconstruction of regulatory and metabolic pathways in metal-reducing delta-proteobacteria
    Dmitry A Rodionov
    Institute for Information Transmission Problems, Russian Academy of Sciences, Bolshoi Karetny per, 19, Moscow 127994, Russia
    Genome Biol 5:R90. 2004
    ....
  7. pmc Extensive parallelism in protein evolution
    Georgii A Bazykin
    Life Sciences Institute and Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109 2216, USA
    Biol Direct 2:20. 2007
    ..However, parallel accumulation of identical changes is also common, especially in traits with only a small number of possible states...
  8. pmc Comparative genomic reconstruction of transcriptional networks controlling central metabolism in the Shewanella genus
    Dmitry A Rodionov
    Sanford Burnham Medical Research Institute, La Jolla, California, USA
    BMC Genomics 12:S3. 2011
    ..The comparative genomics approaches and computational identification of regulatory sites are useful for the in silico reconstruction of transcriptional regulatory networks in bacteria...
  9. pmc Short sequence motifs, overrepresented in mammalian conserved non-coding sequences
    Simon Minovitsky
    Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    BMC Genomics 8:378. 2007
    ..CNSs differ from other genomic sequences in their nucleotide composition and must play important functional roles, which mostly remain obscure...
  10. pmc SNP-VISTA: an interactive SNP visualization tool
    Nameeta Shah
    Institute for Data Analysis and Visualization, IDAV, Department of Computer Science, University of California, Davis, One ShieldsAve, Davis, CA 95616, USA
    BMC Bioinformatics 6:292. 2005
    ..The program is available at http://genome.lbl.gov/vista/snpvista1...
  11. ncbi request reprint The computational challenges of applying comparative-based computational methods to whole genomes
    Inna Dubchak
    Lawrence Berkeley National Laboratory, National Energy Resesarch Scientific Computing Center, CA 94720, USA
    Brief Bioinform 3:18-22. 2002
    ....
  12. pmc Multi-species sequence comparison: the next frontier in genome annotation
    Inna Dubchak
    Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Genome Biol 4:122. 2003
    ....
  13. ncbi request reprint Recognition of a protein fold in the context of the Structural Classification of Proteins (SCOP) classification
    I Dubchak
    E O Lawrence Berkeley National Laboratory, University of California, Berkeley 94720, USA
    Proteins 35:401-7. 1999
    ..The method is applicable for the fold assignment of any protein sequence with or without significant sequence homology to known proteins. A WWW page for predicting protein folds is available at URL http://cbcg.lbl.gov/...
  14. pmc RegPrecise: a database of curated genomic inferences of transcriptional regulatory interactions in prokaryotes
    Pavel S Novichkov
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA, State Scientific Center GosNIIGenetika, Moscow 117545, Russia
    Nucleic Acids Res 38:D111-8. 2010
    ..Another section in the database represents the results of accurate regulon propagation to the closely related genomes...
  15. ncbi request reprint TreeQ-VISTA: an interactive tree visualization tool with functional annotation query capabilities
    Shengyin Gu
    Institute for Data Analysis and Visualization IDAV, Department of Computer Science, University of California, Davis, One Shields Ave, Davis, CA 95616, USA
    Bioinformatics 23:764-6. 2007
    ..AVAILABILITY: The program, detailed tutorial and examples are available online (http:/genome.lbl.gov/vista/TreeQVista)...
  16. ncbi request reprint VISTA : visualizing global DNA sequence alignments of arbitrary length
    C Mayor
    National Energy Research Scientific Computing Center Genome Sciences Department, Berkeley, CA 94720, USA
    Bioinformatics 16:1046-7. 2000
    ..It is currently available on the web, thus allowing for easy access by all researchers...
  17. ncbi request reprint Protein folding class predictor for SCOP: approach based on global descriptors
    I Dubchak
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA ildubchak
    Proc Int Conf Intell Syst Mol Biol 5:104-7. 1997
    ..It is shown that a specific amino acid's properties work completely differently on different folding classes. This creates the possibility of finding an individual set of descriptors that works best on a particular folding class...
  18. pmc Strategies and tools for whole-genome alignments
    Olivier Couronne
    Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Genome Res 13:73-80. 2003
    ..We describe the use of these tools to identify conserved non-coding regions between the human and mouse genomes, some of which have not been identified by other methods...
  19. pmc VISTA Enhancer Browser--a database of tissue-specific human enhancers
    Axel Visel
    Genomics Division, MS 84 171, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA
    Nucleic Acids Res 35:D88-92. 2007
    ..These experimentally validated training sets are expected to provide a basis for a wide range of downstream computational and functional studies of enhancer function...
  20. pmc Multiple whole-genome alignments without a reference organism
    Inna Dubchak
    Genome Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Genome Res 19:682-9. 2009
    ..Our whole-genome multiple alignments are available through the VISTA Browser at http://genome.lbl.gov/vista/index.shtml...
  21. pmc The integrated microbial genomes (IMG) system
    Victor M Markowitz
    Biological Data Management and Technology Center, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA, USA
    Nucleic Acids Res 34:D344-8. 2006
    ..IMG allows users to focus their analysis on subsets of genes and genomes of interest and to save the results of their analysis. IMG is available at http://img.jgi.doe.gov...
  22. pmc IMG/M: a data management and analysis system for metagenomes
    Victor M Markowitz
    Biological Data Management and Technology Center, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, USA
    Nucleic Acids Res 36:D534-8. 2008
    ..IMG/M provides IMG's comparative data analysis tools extended to handle metagenome data, together with metagenome-specific analysis tools. IMG/M is available at http://img.jgi.doe.gov/m...
  23. doi request reprint Obtaining comparative genomic data with the VISTA family of computational tools
    Igor Ratnere
    Lawrence Berkeley National Laboratory, Berkeley, California, USA
    Curr Protoc Bioinformatics . 2009
    ....
  24. pmc The integrated microbial genomes (IMG) system in 2007: data content and analysis tool extensions
    Victor M Markowitz
    Biological Data Management and Technology Center, Genomics Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, USA
    Nucleic Acids Res 36:D528-33. 2008
    ..IMG is provided by the DOE-Joint Genome Institute (JGI) and is available from http://img.jgi.doe.gov...
  25. ncbi request reprint Automatic discovery of sub-molecular sequence domains in multi-aligned sequences: a dynamic programming algorithm for multiple alignment segmentation
    E P Xing
    Center for Bioinformatics and Computational Genomics, NERSC, Berkeley, CA 94720, USA
    J Theor Biol 212:129-39. 2001
    ..This algorithm facilitates the automation of sequence-based molecular structural and evolutionary analyses through statistical modeling and high performance computation...
  26. pmc Computational analysis of candidate intron regulatory elements for tissue-specific alternative pre-mRNA splicing
    M Brudno
    National Energy Research Scientific Computing Center and Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Nucleic Acids Res 29:2338-48. 2001
    ..Our results indicate that this element plays a much wider role than previously appreciated in the regulated tissue-specific splicing of many alternative exons...
  27. pmc AVID: A global alignment program
    Nick Bray
    Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Genome Res 13:97-102. 2003
    ..The tools we have developed for the alignment comparisons, as well as the AVID program, are publicly available. See Web Site References section for AVID Web address and Web addresses for other programs discussed in this paper...
  28. pmc ATGC: a database of orthologous genes from closely related prokaryotic genomes and a research platform for microevolution of prokaryotes
    Pavel S Novichkov
    Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Nucleic Acids Res 37:D448-54. 2009
    ..The ATGC database will be regularly updated following new releases of the NCBI RefSeq. The database is hosted by the Genomics Division at Lawrence Berkeley National laboratory and is publicly available at http://atgc.lbl.gov...
  29. ncbi request reprint SNPs in putative regulatory regions identified by human mouse comparative sequencing and transcription factor binding site data
    Poulabi Banerjee
    Genome Sciences Department, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Mamm Genome 13:554-7. 2002
  30. pmc rVista for comparative sequence-based discovery of functional transcription factor binding sites
    Gabriela G Loots
    Genome Sciences Department, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Genome Res 12:832-9. 2002
    ....
  31. pmc The genome of the Western clawed frog Xenopus tropicalis
    Uffe Hellsten
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA
    Science 328:633-6. 2010
    ..The genome exhibits substantial shared synteny with human and chicken over major parts of large chromosomes, broken by lineage-specific chromosome fusions and fissions, mainly in the mammalian lineage...
  32. pmc RegPredict: an integrated system for regulon inference in prokaryotes by comparative genomics approach
    Pavel S Novichkov
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Nucleic Acids Res 38:W299-307. 2010
    ..An interactive web interface of RegPredict integrates and presents diverse genomic and functional information about the candidate regulon members from several web resources. RegPredict is freely accessible at http://regpredict.lbl.gov...
  33. ncbi request reprint Phylo-VISTA: interactive visualization of multiple DNA sequence alignments
    Nameeta Shah
    Center for Image Processing and Integrated Computing, Department of Computer Science, One Shields Avenue, University of California, Davis, CA 95616 8562, USA
    Bioinformatics 20:636-43. 2004
    ..To be efficient these visualization algorithms must support the ability to accommodate consistently a wide range of evolutionary distances in a comparison framework based upon phylogenetic relationships...
  34. ncbi request reprint In vivo enhancer analysis of human conserved non-coding sequences
    Len A Pennacchio
    US Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA
    Nature 444:499-502. 2006
    ....
  35. ncbi request reprint VISTA family of computational tools for comparative analysis of DNA sequences and whole genomes
    Inna Dubchak
    Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
    Methods Mol Biol 338:69-89. 2006
    ..The web page http://genome.lbl.gov/vista/ serves as a portal for access to all VISTA tools. Our support group can be reached by email at vista@lbl.gov...
  36. ncbi request reprint An experimental metagenome data management and analysis system
    Victor M Markowitz
    Biological Data Management and Technology Center, Lawrence Berkeley National Lab, USA
    Bioinformatics 22:e359-67. 2006
    ..IMG/M provides tools and viewers for analyzing both metagenomes and isolate genomes individually or in a comparative context. IMG/M is available at http://img.jgi.doe.gov/m...
  37. pmc A correlation with exon expression approach to identify cis-regulatory elements for tissue-specific alternative splicing
    Debopriya Das
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Nucleic Acids Res 35:4845-57. 2007
    ..We propose that Fox and CELF proteins play major roles in enforcing the muscle-specific alternative splicing program, facilitating expression of unique isoforms of cytoskeletal proteins critical to muscle cell function...
  38. ncbi request reprint Multi-class protein fold recognition using support vector machines and neural networks
    C H Ding
    NERSC Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720, USA
    Bioinformatics 17:349-58. 2001
    ..Overall, recognition systems achieve 56% fold prediction accuracy on a protein test dataset, where most of the proteins have below 25% sequence identity with the proteins used in training...
  39. ncbi request reprint Comparative analysis and visualization of genomic sequences using VISTA browser and associated computational tools
    Inna Dubchak
    Lawrence Berkeley National Laboratory, USA
    Methods Mol Biol 395:3-16. 2007
    ..VISTA portal (http://genome.lbl.gov/vista) provides access to all these tools...
  40. pmc The splicing regulatory element, UGCAUG, is phylogenetically and spatially conserved in introns that flank tissue-specific alternative exons
    Simon Minovitsky
    Life Sciences Division and Genomics Division, Lawrence Berkeley National Laboratory Berkeley, CA 94720, USA
    Nucleic Acids Res 33:714-24. 2005
    ..We further speculate that highly conserved UGCAUG-binding protein(s) related to the recently described Fox-1 splicing factor play a critical role in mediating this specificity...
  41. pmc Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors
    Sarah De Val
    Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94158 2517, USA
    Cell 135:1053-64. 2008
    ..Finally, we show that FOX:ETS motifs are present in many known endothelial-specific enhancers and that this motif is an efficient predictor of endothelial enhancers in the human genome...
  42. ncbi request reprint Conservation patterns in different functional sequence categories of divergent Drosophila species
    Dmitri Papatsenko
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA
    Genomics 88:431-42. 2006
    ..We discuss how restraining conservation patterns may help in mapping functional sequence categories and improve genome annotation...
  43. pmc A computational approach to identify genes for functional RNAs in genomic sequences
    R J Carter
    Computational and Theoretical Biology Department, Physical Biosciences Division, National Energy Research Scientific Computing Center, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Nucleic Acids Res 29:3928-38. 2001
    ..Public access to our RNA gene predictions and an interface for user predictions is available via the web...
  44. ncbi request reprint The DNA sequence and biology of human chromosome 19
    Jane Grimwood
    Stanford Human Genome Center, Department of Genetics, Stanford University School of Medicine, 975 California Avenue, Palo Alto, California 94304, USA
    Nature 428:529-35. 2004
    ....
  45. ncbi request reprint Genome sequence of the Brown Norway rat yields insights into mammalian evolution
    Richard A Gibbs
    Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, MS BCM226, One Baylor Plaza, Houston, Texas 77030, USA lt http www hgsc bcm tmc edu
    Nature 428:493-521. 2004
    ....
  46. pmc Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution
    Stephen Richards
    Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston Texas 77030, USA
    Genome Res 15:1-18. 2005
    ..Overall, a pattern of repeat-mediated chromosomal rearrangement, and high coadaptation of both male genes and cis-regulatory sequences emerges as important themes of genome divergence between these species of Drosophila...
  47. pmc Automated whole-genome multiple alignment of rat, mouse, and human
    Michael Brudno
    Department of Computer Science, Stanford University, Stanford, California 94305, USA
    Genome Res 14:685-92. 2004
    ..5% of human nucleotides within all alignments agree with the synteny map. The alignments are publicly available online, with visualization through the novel Multi-VISTA browser that we also present...
  48. pmc Characterization of evolutionary rates and constraints in three Mammalian genomes
    Gregory M Cooper
    Department of Genetics, Stanford University, Stanford, California 94305, USA
    Genome Res 14:539-48. 2004
    ..At least 5% of the human genome is under substantial constraint, most of which is noncoding...
  49. ncbi request reprint The amphioxus genome and the evolution of the chordate karyotype
    Nicholas H Putnam
    Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA
    Nature 453:1064-71. 2008
    ..These genome-scale events shaped the vertebrate genome and provided additional genetic variation for exploitation during vertebrate evolution...
  50. pmc RegTransBase--a database of regulatory sequences and interactions in a wide range of prokaryotic genomes
    Alexei E Kazakov
    Institute for Information Transmission Problems, RAS Bolshoi Karetny pereulok 19, Moscow, 127994, Russia
    Nucleic Acids Res 35:D407-12. 2007
    ..RegTransBase also contains manually created position weight matrices (PWM) that can be used to identify candidate regulatory sites in over 60 species. RegTransBase is available at http://regtransbase.lbl.gov...
  51. pmc Integrative annotation of 21,037 human genes validated by full-length cDNA clones
    Tadashi Imanishi
    Integrated Database Group, Biological Information Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan
    PLoS Biol 2:e162. 2004
    ..The H-InvDB platform represents a substantial contribution to resources needed for the exploration of human biology and pathology...
  52. ncbi request reprint Glocal alignment: finding rearrangements during alignment
    Michael Brudno
    Department of Computer Science, Stanford University, Stanford, CA 94305, USA
    Bioinformatics 19:i54-62. 2003
    ....
  53. pmc Cross-species sequence comparisons: a review of methods and available resources
    Kelly A Frazer
    Perlegen Sciences, Mountain View, California 94043, USA
    Genome Res 13:1-12. 2003
    ..In this review, we outline the strategy for choosing DNA sequences from different species for comparative analyses and describe the methods used and the resources publicly available for these studies...
  54. pmc The Chlamydomonas genome reveals the evolution of key animal and plant functions
    Sabeeha S Merchant
    Department of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, CA 90095, USA
    Science 318:245-50. 2007
    ....
  55. ncbi request reprint Initial sequencing and comparative analysis of the mouse genome
    Robert H Waterston
    Genome Sequencing Center, Washington University School of Medicine, Campus Box 8501, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA
    Nature 420:520-62. 2002
    ....
  56. pmc VISTA: computational tools for comparative genomics
    Kelly A Frazer
    Perlegen Sciences, Inc, 2021 Stierlin Court, Mountain View, CA 94043, USA
    Nucleic Acids Res 32:W273-9. 2004
    ..We illustrate capabilities of the VISTA site by the analysis of a 180 kb interval on human chromosome 5 that encodes for the kinesin family member 3A (KIF3A) protein...
  57. pmc The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation
    Brian Palenik
    Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA 92093 0202, USA
    Proc Natl Acad Sci U S A 104:7705-10. 2007
    ..As reported here, selenoenzymes, novel fusion proteins, and loss of some major protein families including ones associated with chromatin are likely important adaptations for achieving a small cell size...
  58. ncbi request reprint Comparative genomics approaches to study organism similarities and differences
    Liping Wei
    Nexus Genomics, Inc, 229 Polaris Ave, Suite 6, Mountain View, CA 94043, USA
    J Biomed Inform 35:142-50. 2002
    ..We also briefly review the currently available computational tools in comparative genomics such as algorithms for genome-scale sequence alignment, gene identification, and nonhomology-based function prediction...

Research Grants6

  1. Comparative Genomics of Non-Coding Regions to Facilitate Translational Research
    Inna Dubchak; Fiscal Year: 2010
    ..This platform will be widely available to clinical investigators through the NIH-supported i2b2 clinical research chart. ..
  2. COMPARATIVE GENOMIC ANALYSIS OF CARDIOVASCULAR GENE REGU
    Inna Dubchak; Fiscal Year: 2003
    ..6) The establishment of an educational program for cardiovascular researchers in the use of genomic databases and tools. ..
  3. Comparative genomics with the VISTA/LAGAN computational system
    Inna Dubchak; Fiscal Year: 2007
    ..The target users of these resources will continue to be biomedical researchers, and thus focus will be placed on generating tools and databases that will be easy to use with readily interpretable results. ..
  4. Comparative Genomics of Non-Coding Regions to Facilitate Translational Research
    Inna Dubchak; Fiscal Year: 2009
    ..This platform will be widely available to clinical investigators through the NIH-supported i2b2 clinical research chart. ..
  5. Comparative genomics with the VISTA/LAGAN computational system
    Inna Dubchak; Fiscal Year: 2009
    ..The target users of these resources will continue to be biomedical researchers, and thus focus will be placed on generating tools and databases that will be easy to use with readily interpretable results. ..