- Ultra-deep mutant spectrum profiling: improving sequencing accuracy using overlapping read pairsHaiyin Chen-Harris
Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA, USA
BMC Genomics 14:96. 2013..The challenge however, is to accurately model the errors in the sequencing data and differentiate real viral mutations, particularly those that exist at low frequencies, from sequencing errors...
- Ultra-deep sequencing of intra-host rabies virus populations during cross-species transmissionMonica K Borucki
Lawrence Livermore National Laboratory, Livermore, California, United States of America
PLoS Negl Trop Dis 7:e2555. 2013..These results suggest that analysis of rare variants within a viral population may yield clues to ancestral genomes and identify rare variants that have the potential to be selected for if environment conditions change. ..
- The role of viral population diversity in adaptation of bovine coronavirus to new host environmentsMonica K Borucki
Lawrence Livermore National Laboratory, Livermore, CA, USA
PLoS ONE 8:e52752. 2013....