Hang Chang

Summary

Affiliation: Lawrence Berkeley National Laboratory
Country: USA

Publications

  1. ncbi Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Med Imaging 32:670-82. 2013
  2. ncbi Multireference level set for the characterization of nuclear morphology in glioblastoma multiforme
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Biomed Eng 59:3460-7. 2012
  3. ncbi Graphical methods for quantifying macromolecules through bright field imaging
    Hang Chang
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Bioinformatics 25:1070-5. 2009
  4. ncbi Morphometic analysis of TCGA glioblastoma multiforme
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
    BMC Bioinformatics 12:484. 2011
  5. ncbi Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture
    Ju Han
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
    PLoS Comput Biol 6:e1000684. 2010
  6. ncbi Iterative voting for inference of structural saliency and characterization of subcellular events
    Bahram Parvin
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Image Process 16:615-23. 2007
  7. ncbi Multidimensional profiling of cell surface proteins and nuclear markers
    Ju Han
    Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    IEEE/ACM Trans Comput Biol Bioinform 7:80-90. 2010
  8. ncbi Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ions
    Torsten Groesser
    Lawrence Berkeley National Laboratory, Life Sciences Division, Department of Cancer and DNA Damage Responses, Berkeley, CA 94720, USA
    Int J Radiat Biol 87:696-710. 2011
  9. ncbi Identification of fluorescent compounds with non-specific binding property via high throughput live cell microscopy
    Sangeeta Nath
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
    PLoS ONE 7:e28802. 2012

Detail Information

Publications9

  1. ncbi Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Med Imaging 32:670-82. 2013
    ..lbl.gov for correlation with TCGA molecular data. The website also provides an interface for panning and zooming of whole mount tissue sections with/without overlaid segmentation results for quality control...
  2. ncbi Multireference level set for the characterization of nuclear morphology in glioblastoma multiforme
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Biomed Eng 59:3460-7. 2012
    ..Experimental results show a superior performance of the proposed method in comparison with present state of art techniques...
  3. ncbi Graphical methods for quantifying macromolecules through bright field imaging
    Hang Chang
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Bioinformatics 25:1070-5. 2009
    ..Compared to classical non-negative matrix factorization, proposed method: (i) improves color decomposition, (ii) has a better noise immunity, (iii) is more invariant to initial conditions and (iv) has a superior computing performance...
  4. ncbi Morphometic analysis of TCGA glioblastoma multiforme
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
    BMC Bioinformatics 12:484. 2011
    ..Thus far, analysis is limited to Glioblastoma Multiforme (GBM) and kidney renal clear cell carcinoma tissue sections. The final results are being distributed for subtyping and linking the histology sections to the genomic data...
  5. ncbi Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture
    Ju Han
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
    PLoS Comput Biol 6:e1000684. 2010
    ..Specifically, PPARgamma has been associated with the invasive stellate morphological phenotype, which corresponds to triple-negative pathobiology. PPARgamma has been validated through two supporting biological assays...
  6. ncbi Iterative voting for inference of structural saliency and characterization of subcellular events
    Bahram Parvin
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Image Process 16:615-23. 2007
    ..Iterative voting has been implemented in both 2-D and 3-D for multi image analysis...
  7. ncbi Multidimensional profiling of cell surface proteins and nuclear markers
    Ju Han
    Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    IEEE/ACM Trans Comput Biol Bioinform 7:80-90. 2010
    ..We demonstrate that multidimensional representations of cell-by-cell phenotypes improve predictive and visualization capabilities among different treatment groups, and identify hidden variables...
  8. ncbi Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ions
    Torsten Groesser
    Lawrence Berkeley National Laboratory, Life Sciences Division, Department of Cancer and DNA Damage Responses, Berkeley, CA 94720, USA
    Int J Radiat Biol 87:696-710. 2011
    ..1) foci formation and removal in proliferating and non-proliferating human mammary epithelial cells (HMEC) after exposure to sparsely and densely ionising radiation under different cell culture conditions...
  9. ncbi Identification of fluorescent compounds with non-specific binding property via high throughput live cell microscopy
    Sangeeta Nath
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
    PLoS ONE 7:e28802. 2012
    ..The non-stickiness property is particularly important for imaging intracellular receptors due to the equilibria involved...