Hang Chang

Summary

Affiliation: Lawrence Berkeley National Laboratory
Country: USA

Publications

  1. ncbi request reprint Characterization of tissue histopathology via predictive sparse decomposition and spatial pyramid matching
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
    Med Image Comput Comput Assist Interv 16:91-8. 2013
  2. pmc Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Med Imaging 32:670-82. 2013
  3. pmc Multireference level set for the characterization of nuclear morphology in glioblastoma multiforme
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Biomed Eng 59:3460-7. 2012
  4. pmc Graphical methods for quantifying macromolecules through bright field imaging
    Hang Chang
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Bioinformatics 25:1070-5. 2009
  5. pmc Morphometic analysis of TCGA glioblastoma multiforme
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
    BMC Bioinformatics 12:484. 2011
  6. pmc Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture
    Ju Han
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
    PLoS Comput Biol 6:e1000684. 2010
  7. doi request reprint Multidimensional profiling of cell surface proteins and nuclear markers
    Ju Han
    Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    IEEE/ACM Trans Comput Biol Bioinform 7:80-90. 2010
  8. ncbi request reprint Iterative voting for inference of structural saliency and characterization of subcellular events
    Bahram Parvin
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Image Process 16:615-23. 2007
  9. pmc Identification of fluorescent compounds with non-specific binding property via high throughput live cell microscopy
    Sangeeta Nath
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
    PLoS ONE 7:e28802. 2012
  10. doi request reprint Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ions
    Torsten Groesser
    Lawrence Berkeley National Laboratory, Life Sciences Division, Department of Cancer and DNA Damage Responses, Berkeley, CA 94720, USA
    Int J Radiat Biol 87:696-710. 2011

Detail Information

Publications11

  1. ncbi request reprint Characterization of tissue histopathology via predictive sparse decomposition and spatial pyramid matching
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
    Med Image Comput Comput Assist Interv 16:91-8. 2013
    ..The novelties of our approach are: (i) extensibility to different tumor types; (ii) robustness in the presence of wide technical and biological variations; and (iii) scalability with varying training sample size...
  2. pmc Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Med Imaging 32:670-82. 2013
    ..lbl.gov for correlation with TCGA molecular data. The website also provides an interface for panning and zooming of whole mount tissue sections with/without overlaid segmentation results for quality control...
  3. pmc Multireference level set for the characterization of nuclear morphology in glioblastoma multiforme
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Biomed Eng 59:3460-7. 2012
    ..Experimental results show a superior performance of the proposed method in comparison with present state of art techniques...
  4. pmc Graphical methods for quantifying macromolecules through bright field imaging
    Hang Chang
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Bioinformatics 25:1070-5. 2009
    ..Compared to classical non-negative matrix factorization, proposed method: (i) improves color decomposition, (ii) has a better noise immunity, (iii) is more invariant to initial conditions and (iv) has a superior computing performance...
  5. pmc Morphometic analysis of TCGA glioblastoma multiforme
    Hang Chang
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
    BMC Bioinformatics 12:484. 2011
    ..Thus far, analysis is limited to Glioblastoma Multiforme (GBM) and kidney renal clear cell carcinoma tissue sections. The final results are being distributed for subtyping and linking the histology sections to the genomic data...
  6. pmc Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture
    Ju Han
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
    PLoS Comput Biol 6:e1000684. 2010
    ..Specifically, PPARgamma has been associated with the invasive stellate morphological phenotype, which corresponds to triple-negative pathobiology. PPARgamma has been validated through two supporting biological assays...
  7. doi request reprint Multidimensional profiling of cell surface proteins and nuclear markers
    Ju Han
    Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    IEEE/ACM Trans Comput Biol Bioinform 7:80-90. 2010
    ..We demonstrate that multidimensional representations of cell-by-cell phenotypes improve predictive and visualization capabilities among different treatment groups, and identify hidden variables...
  8. ncbi request reprint Iterative voting for inference of structural saliency and characterization of subcellular events
    Bahram Parvin
    Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    IEEE Trans Image Process 16:615-23. 2007
    ..Iterative voting has been implemented in both 2-D and 3-D for multi image analysis...
  9. pmc Identification of fluorescent compounds with non-specific binding property via high throughput live cell microscopy
    Sangeeta Nath
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
    PLoS ONE 7:e28802. 2012
    ..The non-stickiness property is particularly important for imaging intracellular receptors due to the equilibria involved...
  10. doi request reprint Persistence of γ-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to γ-rays or iron ions
    Torsten Groesser
    Lawrence Berkeley National Laboratory, Life Sciences Division, Department of Cancer and DNA Damage Responses, Berkeley, CA 94720, USA
    Int J Radiat Biol 87:696-710. 2011
    ..1) foci formation and removal in proliferating and non-proliferating human mammary epithelial cells (HMEC) after exposure to sparsely and densely ionising radiation under different cell culture conditions...
  11. pmc Integrated profiling of three dimensional cell culture models and 3D microscopy
    Cemal Cagatay Bilgin
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Bioinformatics 29:3087-93. 2013
    ..However, they also introduce significant computational challenges, with the main barriers being the effects of growth conditions, fixations and inherent complexities in segmentation that need to be resolved in the 3D volume...