Edward C Lauterbach

Summary

Country: USA

Publications

  1. pmc The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences and the Department of Internal Medicine, Neurology Section, Mercer University School of Medicine, 1400 Coleman Avenue, Macon, GA 31201, USA
    Parkinsons Dis 2012:753548. 2012
  2. pmc Neuroprotective effects of psychotropic drugs in Huntington's disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, 655 First Street, Macon, GA 31201, USA
    Int J Mol Sci 14:22558-603. 2013
  3. ncbi request reprint Toward a more precise, clinically--informed pathophysiology of pathological laughing and crying
    Edward C Lauterbach
    Departments of Psychiatry and Internal Medicine Neurology, Mercer University School of Medicine, 655 First Street, Macon, GA 31201, USA Electronic address
    Neurosci Biobehav Rev 37:1893-916. 2013
  4. doi request reprint Psychotropics regulate Skp1a, Aldh1a1, and Hspa8 transcription--potential to delay Parkinson's disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Neurology Section, Mercer University School of Medicine, Macon, GA 31201, USA
    Prog Neuropsychopharmacol Biol Psychiatry 40:236-9. 2013
  5. doi request reprint An extension of hypotheses regarding rapid-acting, treatment-refractory, and conventional antidepressant activity of dextromethorphan and dextrorphan
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, 1550 College Street, Macon, GA 31201, United States
    Med Hypotheses 78:693-702. 2012
  6. doi request reprint Psychotropic drug effects on gene transcriptomics relevant to Parkinson's disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, GA 31201, USA
    Prog Neuropsychopharmacol Biol Psychiatry 38:107-15. 2012
  7. doi request reprint Psychotropic drug effects on gene transcriptomics relevant to Alzheimer disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, GA 31201, USA
    Alzheimer Dis Assoc Disord 26:1-7. 2012
  8. ncbi request reprint Switching to duloxetine remits ziprasidone - associated urinary incontinence and improves neuropsychiatric behavior in dementia: possible relationship of incontinence to 5HT2 receptor blockade
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, GA, USA
    Psychopharmacol Bull 42:99-105. 2009
  9. doi request reprint Dextromethorphan as a potential rapid-acting antidepressant
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, 1550 College Street, Macon, GA 31201, USA
    Med Hypotheses 76:717-9. 2011
  10. doi request reprint Differential pharmacological responses of catatonia-like signs in frontotemporal dementia
    Edward C Lauterbach
    Mercer University School of Medicine, Macon, GA 31201, USA
    Neurocase 16:436-50. 2010

Detail Information

Publications27

  1. pmc The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences and the Department of Internal Medicine, Neurology Section, Mercer University School of Medicine, 1400 Coleman Avenue, Macon, GA 31201, USA
    Parkinsons Dis 2012:753548. 2012
    ....
  2. pmc Neuroprotective effects of psychotropic drugs in Huntington's disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, 655 First Street, Macon, GA 31201, USA
    Int J Mol Sci 14:22558-603. 2013
    ..Clinical data consist of an uncontrolled lithium case series (n = 3) suggesting non-progression and a primarily negative double-blind, placebo-controlled clinical trial of lamotrigine. ..
  3. ncbi request reprint Toward a more precise, clinically--informed pathophysiology of pathological laughing and crying
    Edward C Lauterbach
    Departments of Psychiatry and Internal Medicine Neurology, Mercer University School of Medicine, 655 First Street, Macon, GA 31201, USA Electronic address
    Neurosci Biobehav Rev 37:1893-916. 2013
    ..Direct activation of the emotional pathway can result in EL and the laughing or crying of gelastic and dacrystic epilepsy. A criterion-based nosology of PLC and EL subtypes is offered. ..
  4. doi request reprint Psychotropics regulate Skp1a, Aldh1a1, and Hspa8 transcription--potential to delay Parkinson's disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Neurology Section, Mercer University School of Medicine, Macon, GA 31201, USA
    Prog Neuropsychopharmacol Biol Psychiatry 40:236-9. 2013
    ..These gene expression findings should be replicated by RT-PCR studies in humans and, if confirmed, these drugs should then be studied in animal models and PD patients...
  5. doi request reprint An extension of hypotheses regarding rapid-acting, treatment-refractory, and conventional antidepressant activity of dextromethorphan and dextrorphan
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, 1550 College Street, Macon, GA 31201, United States
    Med Hypotheses 78:693-702. 2012
    ..Clinical trials may increase our therapeutic armamentarium and our pharmacological understanding of treatment-refractory depression and antidepressant onset of action...
  6. doi request reprint Psychotropic drug effects on gene transcriptomics relevant to Parkinson's disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, GA 31201, USA
    Prog Neuropsychopharmacol Biol Psychiatry 38:107-15. 2012
    ..Effects of these drugs on PD risk gene transcription were therefore surveyed...
  7. doi request reprint Psychotropic drug effects on gene transcriptomics relevant to Alzheimer disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, GA 31201, USA
    Alzheimer Dis Assoc Disord 26:1-7. 2012
    ..This report provides an initial summary and framework to understand the potential impact of psychotropic drugs on AD-relevant genes...
  8. ncbi request reprint Switching to duloxetine remits ziprasidone - associated urinary incontinence and improves neuropsychiatric behavior in dementia: possible relationship of incontinence to 5HT2 receptor blockade
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, GA, USA
    Psychopharmacol Bull 42:99-105. 2009
    ..An understanding of incontinence pharmacology can help the clinician predict and manage this adverse event in treating patients with dementia...
  9. doi request reprint Dextromethorphan as a potential rapid-acting antidepressant
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, 1550 College Street, Macon, GA 31201, USA
    Med Hypotheses 76:717-9. 2011
    ..Clinical trials of dextromethorphan in depressive disorders, especially treatment-resistant depression, now seem warranted...
  10. doi request reprint Differential pharmacological responses of catatonia-like signs in frontotemporal dementia
    Edward C Lauterbach
    Mercer University School of Medicine, Macon, GA 31201, USA
    Neurocase 16:436-50. 2010
    ..Low-dose lorazepam and quetiapine required close monitoring...
  11. doi request reprint Mood and neurobehavioral correlates of cerebellar lesions
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, GA 31201, USA
    Cogn Behav Neurol 23:63-73. 2010
    ..The authors studied mood disorder and neurobehavioral correlates of solitary focal cerebellar (CB) lesions...
  12. doi request reprint Psychopharmacological neuroprotection in neurodegenerative disease: heuristic clinical applications
    Edward C Lauterbach
    Mercer University Center for Translational Studies in Alzheimer s, Parkinson s, and Neurodegenerative Diseases, Macon, GA 31201, USA
    J Neuropsychiatry Clin Neurosci 22:130-54. 2010
    ....
  13. doi request reprint Psychopharmacological neuroprotection in neurodegenerative diseases, part III: criteria-based assessment: a report of the ANPA committee on research
    Edward C Lauterbach
    Department of Psychiatry, Neurology Section, Mercer University School of Medicine, Macon, GA, USA
    J Neuropsychiatry Clin Neurosci 23:242-60. 2011
    ..These preliminary findings can lead to further clinical drug trials on the use of these well-known medications, not only for their psychotropic effects, but also for neuroprotection in NDDs...
  14. doi request reprint Psychopharmacological neuroprotection in neurodegenerative disease: assessing the preclinical data
    Edward C Lauterbach
    Mercer University Center for Translational Studies in Alzheimer s, Parkinson s, and Neurodegenerative Diseases, Macon, GA 31201, USA
    J Neuropsychiatry Clin Neurosci 22:8-18. 2010
    ..A search for clinical studies of neuroprotection revealed only a single study demonstrating putatively positive results for ropinirole. An agenda for research on potentially neuroprotective agent is provided...
  15. ncbi request reprint Differential DSM-III psychiatric disorder prevalence profiles in dystonia and Parkinson's disease
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, Georgia 31201, USA
    J Neuropsychiatry Clin Neurosci 16:29-36. 2004
    ..These findings are considered in light of previous results and in terms of the differences in pallidothalamic physiologies in dystonia and PD. These data suggest distinctive profiles of psychiatric disorders in dystonia and PD...
  16. ncbi request reprint Catatonia and CPK elevation in neurosyphilis: role of plural pharmacodynamic mechanisms
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, GA, USA
    Psychopharmacol Bull 42:53-63. 2009
    ..To report catatonia in neurosyphilis with elevated creatine phosphokinase (CPK) and to understand the pharmacodynamics of catatonia...
  17. ncbi request reprint Correlates of generalized anxiety and panic attacks in dystonia and Parkinson disease
    Edward C Lauterbach
    Departments of Psychiatry and Behavioral Sciences, Internal Medicine Neurology, and Radiology and Family Medicine and Community Medicine of Mercer University School of Medicine, Macon, Georgia 31201, USA
    Cogn Behav Neurol 16:225-33. 2003
    ..To determine prevalences of generalized anxiety, generalized anxiety disorder, panic attacks, and panic disorder in primary dystonia (n = 28) and Parkinson disease (n = 28) and to explore their clinical correlates...
  18. ncbi request reprint The cognitive correlates of functional status: a review from the Committee on Research of the American Neuropsychiatric Association
    Donald R Royall
    Department of Psychiatry, UTHSCSA, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    J Neuropsychiatry Clin Neurosci 19:249-65. 2007
    ..Better integration of cognitive and functional assessments would offer greater clinical utility. However, psychometric batteries may have to be redesigned to maximize their capacity to capture the variance in functional outcomes...
  19. ncbi request reprint The value of quantitative electroencephalography in clinical psychiatry: a report by the Committee on Research of the American Neuropsychiatric Association
    Kerry L Coburn
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, Georgia 31201, USA
    J Neuropsychiatry Clin Neurosci 18:460-500. 2006
    ..As a clinical laboratory test, qEEG's cautious use is recommended in attentional and learning disabilities of childhood, and in mood and dementing disorders of adulthood...
  20. ncbi request reprint Unexplained transient hyperphosphatemia is more common in acute psychiatric disorders than in acute medical-surgical conditions
    Ali Ahmadi
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, 655 First Street, Macon, Georgia 31201, USA
    Psychiatry Res 117:237-43. 2003
    ..These data extend previous findings by linking UTHP to acute psychiatric disturbances across varied psychiatric diagnoses independent of hypercalcemia. Potential explanations include trazodone administration and transient hypocalcemia...
  21. ncbi request reprint The neuropsychiatry of Parkinson's disease and related disorders
    Edward C Lauterbach
    Division of Adult and Geriatric Psychiatry, Mercer University School of Medicine, 655 First Street, Macon, GA 31201, USA
    Psychiatr Clin North Am 27:801-25. 2004
    ..Future research in these Parkinsonian disorders should target the characterization of neuropsychiatric sequelae and their treatment...
  22. ncbi request reprint Cognitive substrates and their treatments in neurodegenerative diseases
    Edward C Lauterbach
    Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, 655 First Street, Macon, Georgia 31201, USA
    Neurol India 54:246-7. 2006
  23. ncbi request reprint The differential diagnosis of pseudobulbar affect (PBA). Distinguishing PBA among disorders of mood and affect. Proceedings of a roundtable meeting
    David B Arciniegas
    Neuropsychiatry Service, Department of Psychiatry, University of Colorado School of Medicine, Denver, Colorado 80211, USA
    CNS Spectr 10:1-14; quiz 15-6. 2005
    ..The material presented in this monograph will help clinicians better recognize, diagnose, and treat PBA, and will form a foundation for understanding and interpreting future studies of this condition...
  24. doi request reprint Antibasal ganglia antibodies, immunomodulation, and antibiotics in "poststreptococcal" adult neuropsychiatric disorders: not yet ready for "prime time"
    Antonio L Teixeira
    Cogn Behav Neurol 21:124-5. 2008
  25. ncbi request reprint Neuropsychiatric complications of traumatic brain injury: a critical review of the literature (a report by the ANPA Committee on Research)
    Edward Kim
    Bristol Myers Squibb Company, Neuroscience Medical Strategy, 777 Scudders Mill Road, Plainsboro, NJ 08536, USA
    J Neuropsychiatry Clin Neurosci 19:106-27. 2007
    ..Larger multicenter prospective studies using standardized diagnostic instruments are needed to further clarify the nosology, risk factors, and clinical course of these disorders. Specific directions for research are provided...
  26. doi request reprint An evidence-based review of the psychopathology of frontotemporal dementia: a report of the ANPA Committee on Research
    Mario F Mendez
    Department of Neurology and Psychiatry, UCLA, USA
    J Neuropsychiatry Clin Neurosci 20:130-49. 2008
    ..The results of this review highlight the distinct neuropsychiatric manifestations of frontotemporal dementia and the need to reconsider the current diagnostic criteria for this disorder...
  27. ncbi request reprint Executive control function: a review of its promise and challenges for clinical research. A report from the Committee on Research of the American Neuropsychiatric Association
    Donald R Royall
    The University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    J Neuropsychiatry Clin Neurosci 14:377-405. 2002
    ..The prevalence and severity of ECF deficits in many disorders remain to be determined, and treatment has been attempted in only a few disorders. Much more research in these areas is necessary...