Research Topics
| Michael D EzekowitzSummaryAffiliation: Lankenau Institute for Medical Research Country: USA Publications
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Detail Information
Publications
Stroke prevention in atrial fibrillation: anticoagulants and antithromboticsMichael D Ezekowitz
Drexel University College of Medicine, 245 North 15th Street MS 470, Room 6608 NCB, Philadelphia, PA 19102, USA
Am Heart Hosp J 2:31-5. 2004..It is highly likely that alternatives to warfarin for stroke prevention will be available in the future and will likely result in a higher utilization rate of anticoagulants in patients with atrial fibrillation...
A randomized trial of budiodarone in paroxysmal atrial fibrillationMichael D Ezekowitz
Lankenau Medical Center, Medical Science Building, Wynnewood, PA 19096, USA
J Interv Card Electrophysiol 34:1-9. 2012..The aim of this study was to investigate the preliminary safety and efficacy of three doses of budiodarone in patients with paroxysmal atrial fibrillation...- Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study)Michael D Ezekowitz
Lankenau Institute for Medical Research and The Heart Center, Wynnewood, PA, USA
Am J Cardiol 100:1419-26. 2007..The 2 highest doses of dabigatran suppress D-dimer concentrations. Serious liver toxicity was not seen. The significance of the increase of DTB2 concentrations in dabigatran-treated patients needs resolution... - Rationale and design of RE-LY: randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatranMichael D Ezekowitz
Lankenau Institute for Medical Research and The Heart Center, Wynnewood, PA, USA
Am Heart J 157:805-10, 810.e1-2. 2009..The worldwide site distribution and broad range of stroke risk further increase the general applicability of the trial. Results are expected in 2009... - The evolving field of stroke prevention in patients with atrial fibrillationMichael D Ezekowitz
Lankenau Institute for Medical Research, 100 Lancaster Avenue, Wynnewood, PA 19096, USA
Stroke 41:S17-20. 2010..Dabigatran is the first agent to show superiority over warfarin for stroke prevention in atrial fibrillation, raising the standard for newer agents... - Dabigatran and warfarin in vitamin K antagonist-naive and -experienced cohorts with atrial fibrillationMichael D Ezekowitz
Lankenau Institute for Medical Research, 100 Lancaster Ave, Suite G36, Wynnewood, PA 19096, USA
Circulation 122:2246-53. 2010..The comparison of anticoagulants dabigatran and warfarin might be most equitable in vitamin K antagonist (VKA)-naive patients... - Dabigatran in atrial fibrillation: pharmacology and clinical trialsMichael D Ezekowitz
Lankenau Institute for Medical Research, 100 Lancaster Avenue, Suite G36, Wynnewood, PA, 19096, USA
J Interv Card Electrophysiol 32:173-80. 2011..Dabigatran, therefore, is the first novel anticoagulant to offer an alternative to warfarin... - Dabigatran versus warfarin in patients with atrial fibrillation: an analysis of patients undergoing cardioversionRangadham Nagarakanti
Louisiana State University School of Medicine, New Orleans, LA, USA
Circulation 123:131-6. 2011..The Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial compared dabigatran 110 mg BID (D110) and 150 mg BID (D150) with warfarin for stroke prevention in 18 113 patients with nonvalvular atrial fibrillation... - Combination antiplatelet therapy for secondary stroke prevention: enhanced efficacy or double trouble?M Haris U Usman
Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, USA
Am J Cardiol 103:1107-12. 2009..Aspirin plus ER-DP has a greater bleeding rate than clopidogrel but a lower rate than aspirin (< or =325 mg/day) alone... - Secondary prevention in concurrent coronary artery, cerebrovascular, and chronic kidney disease: focus on pharmacological therapyLawrence A Notaro
Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA
Cardiovasc Ther 27:199-215. 2009..There are no data supporting the use of aspirin plus clopidogrel in patients with CKD who develop ACS. Aspirin plus clopidogrel is contraindicated for stroke prevention... - Images in cardiovascular medicine. The case of a disappearing left atrial appendage thrombus: direct visualization of left atrial thrombus migration, captured by echocardiography, in a patient with atrial fibrillation, resulting in a strokeAmit Parekh
Lankenau Institute for Medical Research, 100 Lancaster Ave, Wynnewood, PA 19096-3425, USA
Circulation 114:e513-4. 2006 - Department of Veterans Affairs Cooperative Studies Program Clinical Trial comparing combined warfarin and aspirin with aspirin alone in survivors of acute myocardial infarction: primary results of the CHAMP studyLouis D Fiore
Department of Veterans Affairs Cooperative Studies Program Coordinating Center, West Haven, Connecticut, USA
Circulation 105:557-63. 2002..CONCLUSIONS: In post-myocardial infarction patients, warfarin therapy (at a mean international normalized ratio of 1.8) combined with low-dose aspirin did not provide a clinical benefit beyond that achievable with aspirin monotherapy... - Warfarin therapy and systolic hypertension in men with atrial fibrillationSubramanian Krishnan
Department of Medicine, University of Connecticut School of Medicine, Farmington, Connecticut 06516, USA
Am J Hypertens 18:1592-9. 2005..However, it is possible that subjects at higher baseline cardiovascular risk may be more susceptible to the chronic effects of warfarin on arterial hemodynamics... - Combination antithrombotic therapy with antiplatelet agents and anticoagulants for patients with atherosclerotic heart diseaseHeidar Arjomand
Division of Cardiology, Department of Medicine, MCP Hahnemann University Hospitals, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA
J Invasive Cardiol 16:271-8. 2004..0-2.5) in high-risk patients with atherosclerotic heart disease. Combination therapy increases the risk of minor and major bleeding, but not intracranial bleeding... - Anticoagulation in the elderlyAbhay J Dhond
Department of Medicine, Drexel University College of Medicine, Philadelphia, PA 19102, USA
Am J Geriatr Cardiol 12:243-50. 2003.... - Anticoagulation interruptus: not without riskMichael D Ezekowitz
Circulation 110:1518-9. 2004 - The increasing need for anticoagulant therapy to prevent stroke in patients with atrial fibrillationMichael D Ezekowitz
Department of Medicine, Drexel University College of Medicine, Philadelphia, PA 19102, USA
Mayo Clin Proc 79:904-13. 2004.... - Comparison of sotalol versus amiodarone in maintaining stability of sinus rhythm in patients with atrial fibrillation (Sotalol-Amiodarone Fibrillation Efficacy Trial [Safe-T])Steven N Singh
Division of Cardiology, Veterans Affairs Medical Center, Washington, DC 20422, USA
Am J Cardiol 92:468-72. 2003..SAFE-T had randomized 665 patients when enrollment terminated on October 31, 2001. Follow-up of patients continued until October 31, 2002, for a maximum period of 54 months and a minimum period of 12 months for all patients... - Anticoagulation in management of atrial fibrillationMichael D Ezekowitz
Department of Medicine, Drexel University College of Medicine, 245 N 15th Street, Mail Stop 487, Philadelphia, PA 19102, USA
Curr Opin Cardiol 18:26-31. 2003.... - Cholesterol-induced thrombogenicity of the vessel wall: inhibitory effect of fluvastatinMarina Camera
Department of Pharmacological Sciences, University of Milan, Italy
Thromb Haemost 87:748-55. 2002..Fluvastatin treatment reduces the prothrombotic tendency by inhibiting TF synthesis... - Anticoagulation management of valve replacement patientsMichael D Ezekowitz
Department of Medicine, MCP Hahnemann University, Philadelphia, Pennsylvania, USA
J Heart Valve Dis 11:S56-60. 2002..In patients who are hemodynamically stable, thrombolytic therapy is recommended initially... - The impact of patient self-testing of prothrombin time for managing anticoagulation: rationale and design of VA Cooperative Study #481--the Home INR Study (THINRS)David B Matchar
Health Services Research Field Program, Duke University Medical Center, Center for Clinical Health Policy Research, VA Medical Center, 2200 W Main St, Suite 220, Durham, NC, 27705, USA
J Thromb Thrombolysis 19:163-72. 2005..To assess the effect of PST frequency on TTR and other outcomes, at selected sites patients randomized to perform PST are assigned one of three test frequencies (weekly, twice weekly, or once every four weeks)... - Epidemiology and management of new-onset atrial fibrillationKhalid Abusaada
Department of Medicine, Drexel University School of Medicine, Philadelphia, Pennsylvania, USA
Am J Manag Care 10:S50-7. 2004..This article will describe in detail the acute management of AF as well as its epidemiology... - ACC/AHA/Physician Consortium 2008 Clinical Performance Measures for Adults with Nonvalvular Atrial Fibrillation or Atrial Flutter: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and the PhysiciN A Mark Estes
J Am Coll Cardiol 51:865-84. 2008 - ACC/AHA/Physician Consortium 2008 clinical performance measures for adults with nonvalvular atrial fibrillation or atrial flutter: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and the PhysiciN A Mark Estes
Circulation 117:1101-20. 2008 - Letter regarding article by Connolly et al, "Challenges of establishing new antithrombotic therapies in atrial fibrillation"Michael D Ezekowitz
Circulation 117:e149; author reply e150. 2008 - Maintaining sinus rhythm--making treatment better than the diseaseMichael D Ezekowitz
N Engl J Med 357:1039-41. 2007 - Amiodarone versus sotalol for atrial fibrillationBramah N Singh
Department of Veterans Affairs Medical Center, West Los Angeles, Calif 90073, USA
N Engl J Med 352:1861-72. 2005..The optimal pharmacologic means to restore and maintain sinus rhythm in patients with atrial fibrillation remains controversial... - Review of antiplatelet therapy in secondary prevention of cerebrovascular events: a need for direct comparisons between antiplatelet agentsDara G Jamieson
University of Pennsylvania Penn Neurological Institute, USA
J Cardiovasc Pharmacol Ther 10:153-61. 2005.... - Quality of life and exercise performance in patients in sinus rhythm versus persistent atrial fibrillation: a Veterans Affairs Cooperative Studies Program SubstudySteven N Singh
Department of Veterans Affairs Medical Center, Washington, DC 20422, USA
J Am Coll Cardiol 48:721-30. 2006..The purpose of this study was to determine quality of life (QOL) and exercise performance (EP) in patients with persistent atrial fibrillation (AF) converted to sinus rhythm (SR) compared with those remaining in or reverting to AF...