Sergio Waxman

Summary

Affiliation: Lahey Clinic
Country: USA

Publications

  1. ncbi request reprint Intravascular imaging of atherosclerotic human coronaries in a porcine model: a feasibility study
    Sergio Waxman
    Department of Medicine and the Center for Translational Cardiovascular Research, Tufts New England Medical Center, Boston, MA, USA
    Int J Cardiovasc Imaging 24:37-44. 2008
  2. ncbi request reprint Rationale and use of near-infrared spectroscopy for detection of lipid-rich and vulnerable plaques
    Sergio Waxman
    Department of Cardiovascular Medicine, Lahey Clinic, Burlington, MA, USA
    J Nucl Cardiol 14:719-28. 2007
  3. doi request reprint Near-infrared spectroscopy for plaque characterization
    Sergio Waxman
    Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts 01805, USA
    J Interv Cardiol 21:452-8. 2008
  4. ncbi request reprint Detection and treatment of vulnerable plaques and vulnerable patients: novel approaches to prevention of coronary events
    Sergio Waxman
    Department of Cardiovascular Medicine, Lahey Clinic, 41 Mall Rd, Burlington, MA 01805, USA
    Circulation 114:2390-411. 2006
  5. doi request reprint In vivo validation of a catheter-based near-infrared spectroscopy system for detection of lipid core coronary plaques: initial results of the SPECTACL study
    Sergio Waxman
    Lahey Clinic, Burlington, Massachusetts 01805, USA
    JACC Cardiovasc Imaging 2:858-68. 2009
  6. ncbi request reprint High yellow color intensity by angioscopy with quantitative colorimetry to identify high-risk features in culprit lesions of patients with acute coronary syndromes
    Fumiyuki Ishibashi
    Lahey Clinic Medical Center, Burlington, MA, USA
    Am J Cardiol 100:1207-11. 2007
  7. doi request reprint Endothelial progenitor cells delivered into the pericardial space incorporate into areas of ischemic myocardium
    Adam J Saltzman
    Division of Cardiology, Tufts Medical Center, Boston, MA, USA
    Cardiovasc Revasc Med 11:241-8. 2010
  8. pmc Performance of reduced bit-depth acquisition for optical frequency domain imaging
    BRIAN D GOLDBERG
    Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom St, Boston, MA 02114, USA
    Opt Express 17:16957-68. 2009
  9. ncbi request reprint Low power ultrasound delivered through a PTCA-like guidewire: preclinical feasibility and safety of a novel technology for intracoronary thrombolysis
    Sung W Choi
    Division of Cardiology, Center for Translational Cardiovascular Research, Tufts New England Medical Center, Boston, Massachusetts, USA
    J Interv Cardiol 19:87-92. 2006
  10. ncbi request reprint Topographic association of angioscopic yellow plaques with coronary atherosclerotic plaque: assessment with quantitative colorimetry in human coronary artery autopsy specimens
    Fumiyuki Ishibashi
    Lahey Clinic Medical Center, 41 Mall Road, Burlington, MA 01805, USA
    Int J Cardiovasc Imaging 24:1-5. 2008

Detail Information

Publications27

  1. ncbi request reprint Intravascular imaging of atherosclerotic human coronaries in a porcine model: a feasibility study
    Sergio Waxman
    Department of Medicine and the Center for Translational Cardiovascular Research, Tufts New England Medical Center, Boston, MA, USA
    Int J Cardiovasc Imaging 24:37-44. 2008
    ..To perform intravascular imaging of atherosclerotic human coronary conduits in an animal model under conditions of flow and cardiac motion that approximate those encountered in vivo...
  2. ncbi request reprint Rationale and use of near-infrared spectroscopy for detection of lipid-rich and vulnerable plaques
    Sergio Waxman
    Department of Cardiovascular Medicine, Lahey Clinic, Burlington, MA, USA
    J Nucl Cardiol 14:719-28. 2007
  3. doi request reprint Near-infrared spectroscopy for plaque characterization
    Sergio Waxman
    Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts 01805, USA
    J Interv Cardiol 21:452-8. 2008
    ..The final results of the clinical study will be submitted for publication. The potential clinical value of this NIR spectroscopy device is discussed...
  4. ncbi request reprint Detection and treatment of vulnerable plaques and vulnerable patients: novel approaches to prevention of coronary events
    Sergio Waxman
    Department of Cardiovascular Medicine, Lahey Clinic, 41 Mall Rd, Burlington, MA 01805, USA
    Circulation 114:2390-411. 2006
  5. doi request reprint In vivo validation of a catheter-based near-infrared spectroscopy system for detection of lipid core coronary plaques: initial results of the SPECTACL study
    Sergio Waxman
    Lahey Clinic, Burlington, Massachusetts 01805, USA
    JACC Cardiovasc Imaging 2:858-68. 2009
    ..To determine whether catheter-based near-infrared spectroscopy (NIRS) signals obtained with a novel catheter-based system from coronaries of patients are similar to those from autopsy specimens and to assess initial safety of NIRS device...
  6. ncbi request reprint High yellow color intensity by angioscopy with quantitative colorimetry to identify high-risk features in culprit lesions of patients with acute coronary syndromes
    Fumiyuki Ishibashi
    Lahey Clinic Medical Center, Burlington, MA, USA
    Am J Cardiol 100:1207-11. 2007
    ..Coronary angioscopy with quantitative colorimetry could be used to study the association between high-risk coronary lesions and future cardiovascular events...
  7. doi request reprint Endothelial progenitor cells delivered into the pericardial space incorporate into areas of ischemic myocardium
    Adam J Saltzman
    Division of Cardiology, Tufts Medical Center, Boston, MA, USA
    Cardiovasc Revasc Med 11:241-8. 2010
    ..Our objective was to determine whether autologous endothelial progenitor cells (EPCs) delivered into the pericardial space will migrate to and incorporate into ischemic myocardium in a porcine model...
  8. pmc Performance of reduced bit-depth acquisition for optical frequency domain imaging
    BRIAN D GOLDBERG
    Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom St, Boston, MA 02114, USA
    Opt Express 17:16957-68. 2009
    ..Images of a human coronary artery acquired in vivo at 8-bit depth are presented and compared with images at higher bit-depth acquisition...
  9. ncbi request reprint Low power ultrasound delivered through a PTCA-like guidewire: preclinical feasibility and safety of a novel technology for intracoronary thrombolysis
    Sung W Choi
    Division of Cardiology, Center for Translational Cardiovascular Research, Tufts New England Medical Center, Boston, Massachusetts, USA
    J Interv Cardiol 19:87-92. 2006
    ..Low power ultrasound delivered through an angioplasty-like guidewire may be effective for intracoronary thrombolysis. We evaluated the preclinical feasibility and safety of such wire...
  10. ncbi request reprint Topographic association of angioscopic yellow plaques with coronary atherosclerotic plaque: assessment with quantitative colorimetry in human coronary artery autopsy specimens
    Fumiyuki Ishibashi
    Lahey Clinic Medical Center, 41 Mall Road, Burlington, MA 01805, USA
    Int J Cardiovasc Imaging 24:1-5. 2008
    ..Further research using angioscopy could be of value to study the association of high-risk coronaries with acute coronary syndromes...
  11. ncbi request reprint Quantitative colorimetry of atherosclerotic plaque using the L*a*b* color space during angioscopy for the detection of lipid cores underneath thin fibrous caps
    Fumiyuki Ishibashi
    Center for Translational Cardiovascular Research, Tufts New England Medical Center, Boston, MA, USA
    Int J Cardiovasc Imaging 23:679-91. 2007
    ..The purpose of the present study was to test the ability of a quantitative colorimetric system to measure yellow color intensity of atherosclerotic plaques during angioscopy and to characterize the color of LCTCs...
  12. ncbi request reprint Update on coronary angioscopy: review of a 20-year experience and potential application for detection of vulnerable plaque
    Fumiyuki Ishibashi
    Department of Medicine, Cardiology, Lahey Clinic, Burlington, Massachusetts 01805, USA
    J Interv Cardiol 19:17-25. 2006
    ....
  13. ncbi request reprint Near-infrared spectroscopy for the detection of vulnerable coronary artery plaques
    Jay D Caplan
    InfraReDx Inc, Burlington, Massachusetts 01803, USA
    J Am Coll Cardiol 47:C92-6. 2006
    ..Additional studies are planned to validate the ability of the technique to identify lipid-rich coronary artery plaques and ultimately link chemical characterization with subsequent occurrence of an acute coronary syndrome...
  14. pmc Three-dimensional coronary artery microscopy by intracoronary optical frequency domain imaging
    Guillermo J Tearney
    Wellman Center for Photomedicine, Massachusetts General Hospital, Department of Pathology, Harvard Medical School, Boston, Massachusetts 02114, USA
    JACC Cardiovasc Imaging 1:752-61. 2008
    ..We present the first clinical experience with intracoronary optical frequency domain imaging (OFDI) in human patients...
  15. doi request reprint Comparison of procedural times, success rates, and safety between left versus right radial arterial access in primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction
    Peter Larsen
    Department of Interventional Cardiology, Lahey Clinic Medical Center, Burlington, Massachusetts 01803, USA
    Catheter Cardiovasc Interv 78:38-44. 2011
    ....
  16. ncbi request reprint Plaque disruption and thrombus in Ambrose's angiographic coronary lesion types
    Sergio Waxman
    Division of Cardiology, New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts 02111, USA
    Am J Cardiol 92:16-20. 2003
    ..We conclude that Ambrose's type II eccentric stenoses and angiographically complex lesions are strongly associated with disrupted plaques and/or thrombus as assessed by angioscopy in patients and represent unstable plaque substrates...
  17. doi request reprint Clinical characteristics of tako-tsubo cardiomyopathy
    Venkatesan Vidi
    Division of Internal Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts, USA
    Am J Cardiol 104:578-82. 2009
    ..It predominantly involves the apical portion of the left ventricle and patients with this condition have a favorable outcome with appropriate medical management. The precise cause remains unclear...
  18. doi request reprint Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation
    Guillermo J Tearney
    The Massachusetts General Hospital and the Wellman Center for Photomedicine, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 59:1058-72. 2012
    ....
  19. ncbi request reprint Single-center experience with the TandemHeart percutaneous ventricular assist device to support patients undergoing high-risk percutaneous coronary intervention
    Wael Al-Husami
    Lahey Clinic Medical Center, 41 Mall Rd Burlington, MA 01805, USA
    J Invasive Cardiol 20:319-22. 2008
    ..The TandemHeart percutaneous ventricular assist device (THpVAD) may be able to provide the necessary circulatory support required to enhance procedural success and patient safety during high-risk PCI...
  20. ncbi request reprint Potent antifibrillatory effects of intrapericardial nitroglycerin in the ischemic porcine heart
    Kapil Kumar
    Harvard Medical School, Boston, Massachusetts, USA
    J Am Coll Cardiol 41:1831-7. 2003
    ..We investigated the antiarrhythmic effects of intrapericardial nitroglycerin (NTG) during acute myocardial ischemia in the porcine heart...
  21. ncbi request reprint Determination of in vivo velocity and endothelial shear stress patterns with phasic flow in human coronary arteries: a methodology to predict progression of coronary atherosclerosis
    Charles L Feldman
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Mass 02115, USA
    Am Heart J 143:931-9. 2002
    ....
  22. ncbi request reprint Angioscopy and ischemic heart disease
    Adam J Saltzman
    Cardiovascular Division, Department of Internal Medicine, Tufts New England Medical Center, 750 Washington Street, Boston, MA 02111, USA
    Curr Opin Cardiol 17:633-7. 2002
    ..Because of its ability to detect superficial lipid pools, angioscopy may be valuable for the detection of vulnerable plaques...
  23. ncbi request reprint Multiple yellow plaques assessed by angioscopy with quantitative colorimetry in patients with myocardial infarction
    Shigenobu Inami
    Chiba Hokusoh Hospital, Nippon Medical School, Chiba, Japan
    Circ J 72:399-403. 2008
    ....
  24. ncbi request reprint Late coronary stent thrombosis: early vs. late stent thrombosis in the stent era
    Fenwei Wang
    Department of Internal Medicine, Division of Cardiology, University of Texas Medical Branch at Galveston, 301 University Boulevard, Galveston, TX 77555, USA
    Catheter Cardiovasc Interv 55:142-7. 2002
    ..Further studies are required to determine whether longer-term poststent pharmacological treatment may decrease or prevent this complication...
  25. ncbi request reprint From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II
    Morteza Naghavi
    The Center for Vulnerable Plaque Research, University of Texas Houston, The Texas Heart Institute, and President Bush Center for Cardiovascular Health, Memorial Hermann Hospital, Houston, USA
    Circulation 108:1772-8. 2003
    ..We encourage healthcare policy makers to promote translational research for screening and treatment of vulnerable patients...
  26. ncbi request reprint Effect of rosiglitazone on restenosis after coronary stenting in patients with type 2 diabetes
    Abdulfatah Osman
    Division of Cardiology, University of Texas Medical Branch, Galveston, Texas, USA
    Am Heart J 147:e23. 2004
    ..Thiazolidinediones have been shown to have an antiproliferative vascular effect in experimental models. We sought to study the effect of rosiglitazone on in-stent restenosis in patients with established type 2 diabetes...
  27. ncbi request reprint From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I
    Morteza Naghavi
    The Center for Vulnerable Plaque Research, University of Texas Houston, The Texas Heart Institute, and President Bush Center for Cardiovascular Health, Memorial Hermann Hospital, Houston, USA
    Circulation 108:1664-72. 2003
    ..We encourage healthcare policy makers to promote translational research for screening and treatment of vulnerable patients...