Research Topics
| Richard W NestoSummaryAffiliation: Lahey Clinic Country: USA Publications
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Detail Information
Publications
C-reactive protein, its role in inflammation, Type 2 diabetes and cardiovascular disease, and the effects of insulin-sensitizing treatment with thiazolidinedionesR Nesto
Department of Cardiovascular Medicine, Lahey Clinic, Burlington, MA 01805, USA
Diabet Med 21:810-7. 2004....
Beyond low-density lipoprotein: addressing the atherogenic lipid triad in type 2 diabetes mellitus and the metabolic syndromeRichard W Nesto
Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts 02493, USA
Am J Cardiovasc Drugs 5:379-87. 2005....
Obesity: a major component of the metabolic syndromeRichard W Nesto
Department of Cardiovascular Medicine, Harvard Medical School, Lahey Clinic Medical Center, Burlington, Massachusetts 01805, USA
Tex Heart Inst J 32:387-9. 2005
Managing cardiovascular risk inpatients with metabolic syndromeRichard W Nesto
Department of Cardiovascular Medicine, Lahey Clinical Medical Center, Burlington, Massachusetts 01805, USA
Clin Cornerstone 7:46-51. 2005....
Guiding clinical decisions on abdominal obesity and cardiometabolic riskRichard W Nesto
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, 41 Mall Road, Burlington, MA 01805, USA
Clin Cornerstone 9:43-52; discussion 53-4. 2009..However, the benefits associated with the pharmacologic management of weight loss must be weighed against the potential for drug-related adverse events...
In vivo validation of a catheter-based near-infrared spectroscopy system for detection of lipid core coronary plaques: initial results of the SPECTACL studySergio Waxman
Lahey Clinic, Burlington, Massachusetts 01805, USA
JACC Cardiovasc Imaging 2:858-68. 2009..To determine whether catheter-based near-infrared spectroscopy (NIRS) signals obtained with a novel catheter-based system from coronaries of patients are similar to those from autopsy specimens and to assess initial safety of NIRS device...
Prevalence of metabolic syndrome in patients < or =45 years of age with acute myocardial infarction having percutaneous coronary interventionEugene H Chung
Lahey Clinic Medical Center, Burlington, Massachusetts, USA
Am J Cardiol 100:1052-5. 2007..The prevalence of smoking, male gender, and family history of premature coronary artery disease were the same for the 2 groups. In conclusion, MS was highly prevalent in this population of young patients with acute myocardial infarction...
High yellow color intensity by angioscopy with quantitative colorimetry to identify high-risk features in culprit lesions of patients with acute coronary syndromesFumiyuki Ishibashi
Lahey Clinic Medical Center, Burlington, MA, USA
Am J Cardiol 100:1207-11. 2007..Coronary angioscopy with quantitative colorimetry could be used to study the association between high-risk coronary lesions and future cardiovascular events...
Type 2 diabetes and coronary heart disease: focus on myocardial infarctionRodrigo M Lago
Lahey Clinic Medical Center, 41 Mall Road, Burlington, MA 01805, USA
Curr Diab Rep 9:73-8. 2009..Aggressive medical therapy and careful modulation of glucose metabolism in the acute and follow-up phase of a myocardial infarction may favorably influence outcome...
Clinical characteristics of tako-tsubo cardiomyopathyVenkatesan Vidi
Division of Internal Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts, USA
Am J Cardiol 104:578-82. 2009..It predominantly involves the apical portion of the left ventricle and patients with this condition have a favorable outcome with appropriate medical management. The precise cause remains unclear...
Myocardial infarction as a presentation of clinical in-stent restenosisAtasu K Nayak
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, MA 01805, USA
Circ J 70:1026-9. 2006..Renal failure and acute coronary syndromes at the initial procedure are associated with MI...
Implications of intensive glycemic control on cardiovascular disease: early reports from the ACCORD and ADVANCE TrialsShin Soo Yeon
Harvard Medical School, Boston, Massachusetts, USA
Rev Cardiovasc Med 9:1-4. 2008
Retroperitoneal hemorrhage from inferior epigastric artery: value of femoral angiography for detection and managementAkio Kawamura
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts 01805, USA
Catheter Cardiovasc Interv 68:267-70. 2006..We report on two cases of retroperitoneal bleeding from unintentional puncture of the inferior epigastric artery during cardiac catheterization. Femoral angiography is a valuable tool to promptly recognize this complication...
Myocardial glucose transport and utilization: a target for therapeutic interventionPremranjan P Singh
Harvard Medical School, Boston, MA and Lahey Clinic Medical Center, Burlington, Massachusetts, USA
Rev Cardiovasc Med 9:106-10. 2008..Optimization of cardiac metabolism could become a new target for therapeutic intervention in patients with ischemic heart disease and diabetes...
Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trialsRodrigo M Lago
Lahey Clinic Medical Center, Burlington, MA, USA
Lancet 370:1129-36. 2007..We aimed to examine the risk of congestive heart failure and of cardiac death in patients given TZDs...
Influence of diabetes and/or myocardial infarction on prevalence of abnormal T-wave alternansDavid T Martin
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, MA 01805, USA
Ann Noninvasive Electrocardiol 14:355-9. 2009..The presence of diabetes (DM) is associated with an increased risk of sudden death but there is limited data on the impact of DM and previous myocardial infarction (MI) on TWA prevalence...
Prevalence of newly diagnosed diabetes in clinical settingsRichard W Nesto
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts, USA
Rev Cardiovasc Med 7:S18-24. 2006..The prevalence of hyperglycemia in patients admitted with acute cardiovascular disease and the effect of hyperglycemia on outcome are reviewed...
Gastric volvulus presenting as an acute coronary syndromeSatish Sivasankaran
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts 01805, USA
Tex Heart Inst J 33:266-8. 2006
Cardiac resynchronization therapy reduces the risk of cardiac events in patients with diabetes enrolled in the multicenter automatic defibrillator implantation trial with cardiac resynchronization therapy (MADIT-CRT)David T Martin
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, MA 01805, USA
Circ Heart Fail 4:332-8. 2011..Data are limited regarding whether the presence of diabetes mellitus (DM) influences the benefit of cardiac resynchronization with defibrillator therapy (CRT-D) in heart failure (HF) patients...
Near-infrared spectroscopy for the detection of vulnerable coronary artery plaquesJay D Caplan
InfraReDx Inc, Burlington, Massachusetts 01803, USA
J Am Coll Cardiol 47:C92-6. 2006..Additional studies are planned to validate the ability of the technique to identify lipid-rich coronary artery plaques and ultimately link chemical characterization with subsequent occurrence of an acute coronary syndrome...
The relation of insulin resistance syndromes to risk of cardiovascular diseaseRichard W Nesto
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts, USA
Rev Cardiovasc Med 4:S11-8. 2003..This article reviews the relationship between diabetes and the risk of CVD...
Incidence of metabolic syndrome and insulin resistance in a population with organic erectile dysfunctionTina C Bansal
Center for Sexual Function/Endocrinology, Lahey Clinic Medical Center, Burlington, MA, USA
J Sex Med 2:96-103. 2005..Early detection of metabolic disease in patients with ED may be a gateway to the reduction endothelial dysfunction in younger men with increased cardiovascular risk but who present for treatment of ED alone...
Impact of glucose intolerance and insulin resistance on cardiac structure and function: sex-related differences in the Framingham Heart StudyMartin K Rutter
Framingham Heart Study, Burlington, Mass, USA
Circulation 107:448-54. 2003..Insulin resistance was associated with increased LV mass in women alone, but this relation was largely accounted for by obesity...
Pharmacological treatment and prevention of heart failure in the diabetic patientRichard W Nesto
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts, USA
Rev Cardiovasc Med 5:1-8. 2004..B-Blockers remain underused in the diabetic population despite overwhelming evidence of their efficacy in treating heart failure in patients with diabetes...
Impact of gender on in-hospital outcomes following contemporary percutaneous intervention for peripheral arterial diseaseAkio Kawamura
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, 41 Mall Road, Burlington, MA 01805, USA
J Invasive Cardiol 17:433-6. 2005..The purpose of this study was to assess the gender differences on in-hospital outcomes of patients undergoing PPAI...
Atheromatous plaque cap thickness can be determined by quantitative color analysis during angioscopy: implications for identifying the vulnerable plaqueAkira Miyamoto
Institute for Prevention of Cardiovascular Disease, Cardiovascular Division, Department of Medicine, Deaconess Hospital, Harvard Medical School, Boston, Massachusetts, USA
Clin Cardiol 27:9-15. 2004..75 to 0.88). CONCLUSION: Plaque cap thickness is a determinant of plaque color, and this can be assessed by quantitative colorimetry. Thus, plaque color by angioscopy may be useful for detecting vulnerable plaques...
Correlation between cardiovascular disease and diabetes mellitus: current conceptsRichard W Nesto
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts, USA
Am J Med 116:11S-22S. 2004..Such interventions may include well-established treatments for hypertension and dyslipidemia, diet improvements, weight loss, and exercise as well as novel pharmacologic interventions aimed at newly identified therapeutic targets...
Diabetes, hyperglycemia, and the cardiologist: a call to action for optimizing care. IntroductionRichard W Nesto
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts, USA
Rev Cardiovasc Med 7:S1-2. 2006
Targeting the use of glycoprotein IIb/IIIa antagonists--the diabetic patientHans K Meier-Ewert
Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts, USA
Rev Cardiovasc Med 3:S20-7. 2002..The ACC/AHA 2002 guidelines for the management of acute coronary syndromes recommend the use of abciximab in diabetic patients undergoing stent implantation...
A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in CaucasiansXiaowei Ma
Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA
Hum Mol Genet 13:2197-205. 2004..In conclusion, this comprehensive study of CD36 variability indicates that the common polymorphisms at this locus modulate lipid metabolism and cardiovascular risk in Caucasians...
Modifications of coronary risk factorsJeanine Albu
The New York Obesity Research Center, St Luke s Roosevelt Hospital Center, University Hospital of Columbia University, College of Physicians and Surgeons, Columbia University, New York, New York 10025, USA
Am J Cardiol 97:41G-52G. 2006....
The insulin resistance syndrome and coronary artery diseaseDavid M Kendall
International Diabetes Center, Park Nicollet Clinic, 3800 Park Nicollet Blvd, St Louis Park, MN 55416, USA
Coron Artery Dis 14:335-48. 2003..A proposed approach to the management of patients with the insulin resistance syndrome is discussed...
Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003Richard W Nesto
Circulation 108:2941-8. 2003
Cardiometabolic risk and risk management. IntroductionRichard W Nesto
Clin Cornerstone 8:9-10. 2007
Antiplatelet therapy in populations at high risk of atherothrombosisDavid P Faxon
Section of Cardiology, Department of Medicine, University of Chicago, 5841 S Maryland Ave, Room B 608, MC 6080, Chicago, IL 60637, USA
J Natl Med Assoc 98:711-21. 2006....
Primary prevention of cardiovascular diseases in people with diabetes mellitus: a scientific statement from the American Heart Association and the American Diabetes AssociationJohn B Buse
University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
Diabetes Care 30:162-72. 2007..This statement will attempt to harmonize the recommendations of both organizations where possible but will recognize areas in which AHA and ADA recommendations differ...
Glucose, insulin, and potassium for metabolic support in acute myocardial infarction: is the jury still out?Howard J Broder
Division of Cardiology, Cedars Sinai Medical Center, Los Angeles, California, USA
Rev Cardiovasc Med 7:S44-50. 2006....
Diabetes and residual risk of coronary heart diseaseRichard W Nesto
Nat Clin Pract Endocrinol Metab 3:71. 2007
The platelet in diabetes: focus on prevention of ischemic eventsJohn A Colwell
Diabetes Center, Medical University of South Carolina, Charleston, South Carolina, USA
Diabetes Care 26:2181-8. 2003..Recent studies support the use of clopidogrel in addition to standard therapy, as well as the use of GpIIb-IIIa inhibitors in ACS patients...
Implications and treatment of acute hyperglycemia in the setting of acute myocardial infarctionStuart W Zarich
Division of Cardiovascular Medicine, Bridgeport Hospital, Yale University School of Medicine, New Haven, Conn, USA
Circulation 115:e436-9. 2007
Ischemia imaging and plaque imaging in diabetes: Complementary tools to improve cardiovascular risk management: Response to Raggi et alMartin K Rutter
Diabetes Care 29:1187; author reply 1188. 2006
Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes AssociationRichard W Nesto
American Diabetes Association
Diabetes Care 27:256-63. 2004
Primary prevention of cardiovascular diseases in people with diabetes mellitus: a scientific statement from the American Heart Association and the American Diabetes AssociationJohn B Buse
University of North Carolina, USA
Circulation 115:114-26. 2007..This statement will attempt to harmonize the recommendations of both organizations where possible but will recognize areas in which AHA and ADA recommendations differ...
Diabetes and hypertensionRodrigo M Lago
Nat Clin Pract Endocrinol Metab 3:667. 2007
Cardiac abnormalities in diabetic patients with neuropathy: effects of aldose reductase inhibitor administrationBrian F Johnson
Pfizer Research, Groton, Connecticut, USA
Diabetes Care 27:448-54. 2004..There was no change in resting diastolic filling rates in either group. CONCLUSIONS: Diabetic patients with neuropathy have LV abnormalities that can be stabilized and partially reversed by ARI treatment...
The CHARISMA trial and the REACH registry outcomesDavid P Faxon
J Natl Med Assoc 98:1713. 2006
