William H Gaasch

Summary

Affiliation: Lahey Clinic
Country: USA

Publications

  1. doi request reprint Left ventricular structural remodeling in health and disease: with special emphasis on volume, mass, and geometry
    William H Gaasch
    Department of Cardiovascular Medicine, Lahey Clinic, 14 Mall Road, Burlington, Massachusetts 01805, USA
    J Am Coll Cardiol 58:1733-40. 2011
  2. ncbi request reprint Left ventricular diastolic dysfunction and diastolic heart failure
    William H Gaasch
    Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts 01805, USA
    Annu Rev Med 55:373-94. 2004
  3. doi request reprint Distribution of left ventricular ejection fraction in patients with ischemic and hypertensive heart disease and chronic heart failure
    William H Gaasch
    Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts, USA
    Am J Cardiol 104:1413-5. 2009
  4. doi request reprint Patterns of structural and functional remodeling of the left ventricle in chronic heart failure
    William H Gaasch
    Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts, USA
    Am J Cardiol 102:459-62. 2008
  5. doi request reprint Prevalence and clinical characteristics of nondilated cardiomyopathy and the effect of atrial fibrillation
    Alexander Doumas
    Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts
    Am J Cardiol 105:884-7. 2010
  6. ncbi request reprint Diagnostic criteria for diastolic heart failure
    R Frederick Yturralde
    Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, MA 01805, USA
    Prog Cardiovasc Dis 47:314-9. 2005
  7. ncbi request reprint Anthropometric normalization of left ventricular size in chronic mitral regurgitation
    Roshan K Mathew
    Echocardiography Laboratory, Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts 01805, USA
    Am J Cardiol 91:762-4. 2003
  8. ncbi request reprint Regurgitant lesions of the aortic and mitral valves: considerations in determining the ideal timing of surgical intervention
    Edmund A Bermudez
    Lahey Clinic, Burlington, MA 01805, USA
    Heart Fail Clin 2:473-82. 2006
  9. ncbi request reprint Contractile behavior of the left ventricle in diastolic heart failure: with emphasis on regional systolic function
    Gerard P Aurigemma
    Division of Cardiology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Circulation 113:296-304. 2006
  10. ncbi request reprint Left ventricular systolic performance, function, and contractility in patients with diastolic heart failure
    Catalin F Baicu
    Division of Cardiology, Department of Medicine, Medical University of South Carolina and RHJ Department of Veterans Affairs Medical Center, Charleston, SC 29425, USA
    Circulation 111:2306-12. 2005

Collaborators

Detail Information

Publications20

  1. doi request reprint Left ventricular structural remodeling in health and disease: with special emphasis on volume, mass, and geometry
    William H Gaasch
    Department of Cardiovascular Medicine, Lahey Clinic, 14 Mall Road, Burlington, Massachusetts 01805, USA
    J Am Coll Cardiol 58:1733-40. 2011
    ..Considering all patients with LV hypertrophy as a homogenous group is inconsistent with our understanding of the various remodeling patterns that are discussed in this review...
  2. ncbi request reprint Left ventricular diastolic dysfunction and diastolic heart failure
    William H Gaasch
    Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts 01805, USA
    Annu Rev Med 55:373-94. 2004
    ..g., venous congestion), and the second is to eliminate or reduce the factors responsible for diastolic dysfunction (e.g., myocardial hypertrophy, fibrosis, and ischemia)...
  3. doi request reprint Distribution of left ventricular ejection fraction in patients with ischemic and hypertensive heart disease and chronic heart failure
    William H Gaasch
    Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts, USA
    Am J Cardiol 104:1413-5. 2009
    ..In conclusion, the observed bimodal distribution of EF in patients with chronic HF is a reflection of 2 HF phenotypes with different underlying pathophysiologic features...
  4. doi request reprint Patterns of structural and functional remodeling of the left ventricle in chronic heart failure
    William H Gaasch
    Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts, USA
    Am J Cardiol 102:459-62. 2008
    ..In conclusion, these patterns of remodeling encompass a wide spectrum of geometric changes with different clinical and pathophysiologic features and possibly different management strategies...
  5. doi request reprint Prevalence and clinical characteristics of nondilated cardiomyopathy and the effect of atrial fibrillation
    Alexander Doumas
    Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts
    Am J Cardiol 105:884-7. 2010
    ..45 had nondilated cardiomyopathy, often with LV hypertrophic remodeling and/or AF. An improvement in LV function can be expected in many patients with nondilated cardiomyopathy, particularly those with AF...
  6. ncbi request reprint Diagnostic criteria for diastolic heart failure
    R Frederick Yturralde
    Department of Cardiovascular Medicine, Lahey Clinic Medical Center, Burlington, MA 01805, USA
    Prog Cardiovasc Dis 47:314-9. 2005
    ..The diagnosis is confirmed if there is evidence of ventricular hyperthrophy and/or concentric remodeling, left atrial enlargement, or laboratory evidence of diastolic dysfunction...
  7. ncbi request reprint Anthropometric normalization of left ventricular size in chronic mitral regurgitation
    Roshan K Mathew
    Echocardiography Laboratory, Department of Cardiovascular Medicine, Lahey Clinic, Burlington, Massachusetts 01805, USA
    Am J Cardiol 91:762-4. 2003
  8. ncbi request reprint Regurgitant lesions of the aortic and mitral valves: considerations in determining the ideal timing of surgical intervention
    Edmund A Bermudez
    Lahey Clinic, Burlington, MA 01805, USA
    Heart Fail Clin 2:473-82. 2006
  9. ncbi request reprint Contractile behavior of the left ventricle in diastolic heart failure: with emphasis on regional systolic function
    Gerard P Aurigemma
    Division of Cardiology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Circulation 113:296-304. 2006
  10. ncbi request reprint Left ventricular systolic performance, function, and contractility in patients with diastolic heart failure
    Catalin F Baicu
    Division of Cardiology, Department of Medicine, Medical University of South Carolina and RHJ Department of Veterans Affairs Medical Center, Charleston, SC 29425, USA
    Circulation 111:2306-12. 2005
    ..Whether and to what extent these abnormalities in diastolic function occur in association with abnormalities in LV systolic performance, function, and contractility has not been investigated thoroughly...
  11. ncbi request reprint Heart failure in pressure overload hypertrophy. The relative roles of ventricular remodeling and myocardial dysfunction
    Gavin R Norton
    Laboratory of Cardiovascular Pathophysiology, Department of Physiology, University of the Witwatersrand, Johannesburg, South Africa
    J Am Coll Cardiol 39:664-71. 2002
    ..We sought to explore the relative contributions of ventricular remodeling and myocardial dysfunction to heart failure in pressure overload hypertrophy (POH)...
  12. ncbi request reprint Lack of relationship between Doppler indices of diastolic function and left ventricular pressure transients in patients with definite diastolic heart failure
    Gerard P Aurigemma
    Department of Medicine, Division of Cardiology, University of Massachusetts Medical School, Worcester, Mass 01655, USA
    Am Heart J 148:E12. 2004
    ..The purpose of this study was to compare invasive with noninvasive indices of diastolic function in a well-defined group of patients with diastolic dysfunction and a history of diastolic heart failure...
  13. ncbi request reprint Symptoms and left ventricular size and function in patients with chronic aortic regurgitation
    William H Gaasch
    J Am Coll Cardiol 41:1325-8. 2003
  14. ncbi request reprint Diastolic heart failure--abnormalities in active relaxation and passive stiffness of the left ventricle
    Michael R Zile
    Cardiology Division, Department of Medicine, Gazes Cardiac Research Institute, Medical University of South Carolina, Charleston 29425, USA
    N Engl J Med 350:1953-9. 2004
    ..It has traditionally been thought that the pathophysiological cause of heart failure in these patients is an abnormality in the diastolic properties of the left ventricle; however, this hypothesis remains largely unproven...
  15. ncbi request reprint Usefulness of clinical variables, echocardiography, and levels of brain natriuretic peptide and norepinephrine to distinguish systolic and diastolic causes of acute heart failure
    Craig S Vinch
    Division of Cardiology, Department of Medicine, The University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 91:1140-3. 2003
  16. ncbi request reprint Heart failure in aortic stenosis - improving diagnosis and treatment
    Michael R Zile
    Cardiology Division, Department of Medicine, Gazes Cardiac Research Institute, Medical University of South Carolina, Charleston, USA
    N Engl J Med 348:1735-6. 2003
  17. doi request reprint Cardiopulmonary exercise variables in diastolic versus systolic heart failure
    Mary Jane Farr
    Division of Cardiology, Columbia University, New York, New York, USA
    Am J Cardiol 102:203-6. 2008
    ..3, diastolic HF vs systolic HF). In conclusion, the CPX response in patients with diastolic HF and systolic HF is markedly abnormal and indistinguishable with regard to peak VO(2) and ventilation despite marked differences in the LV EF...
  18. ncbi request reprint Assessment of left ventricular diastolic function and recognition of diastolic heart failure
    William H Gaasch
    Circulation 116:591-3. 2007
  19. ncbi request reprint Clinical practice. Diastolic heart failure
    Gerard P Aurigemma
    Division of Cardiology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    N Engl J Med 351:1097-105. 2004
  20. ncbi request reprint Low flow-low gradient aortic stenosis: the pathologist weighs in
    Gerard P Aurigemma
    J Am Coll Cardiol 44:1856-8. 2004