Erika Assarsson

Summary

Affiliation: La Jolla Institute for Allergy and Immunology
Country: USA

Publications

  1. ncbi request reprint 2B4 co-stimulation: NK cells and their control of adaptive immune responses
    Erika Assarsson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, F59, Karolinska University Hospital Huddinge, S 14186 Stockholm, Sweden
    Mol Immunol 42:419-23. 2005
  2. ncbi request reprint NK cells stimulate proliferation of T and NK cells through 2B4/CD48 interactions
    Erika Assarsson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Huddinge University Hospital, SE 141 86 Stockholm, Sweden
    J Immunol 173:174-80. 2004
  3. ncbi request reprint Severe defect in thymic development in an insertional mutant mouse model
    Erika Assarsson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    J Immunol 178:5018-27. 2007
  4. ncbi request reprint 2B4/CD48-mediated regulation of lymphocyte activation and function
    Erika Assarsson
    Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Immunol 175:2045-9. 2005
  5. pmc Definition of epitopes and antigens recognized by vaccinia specific immune responses: their conservation in variola virus sequences, and use as a model system to study complex pathogens
    Alessandro Sette
    Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA
    Vaccine 27:G21-6. 2009
  6. pmc Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?
    Maya F Kotturi
    Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA
    Immunome Res 5:3. 2009
  7. pmc TiArA: a virtual appliance for the analysis of Tiling Array data
    Jason A Greenbaum
    Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
    PLoS ONE 5:e9993. 2010
  8. ncbi request reprint Cytokine-induced killer T cells kill immature dendritic cells by TCR-independent and perforin-dependent mechanisms
    Pramod S Joshi
    Department of Pathology and Comprehensive Cancer Center, The Ohio State University Medical Center, 129 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210, USA
    J Leukoc Biol 80:1345-53. 2006
  9. ncbi request reprint A quantitative analysis of the variables affecting the repertoire of T cell specificities recognized after vaccinia virus infection
    Erika Assarsson
    Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA
    J Immunol 178:7890-901. 2007
  10. ncbi request reprint Memory CD8+ T cells provide an early source of IFN-gamma
    Taku Kambayashi
    Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Immunol 170:2399-408. 2003

Collaborators

Detail Information

Publications10

  1. ncbi request reprint 2B4 co-stimulation: NK cells and their control of adaptive immune responses
    Erika Assarsson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, F59, Karolinska University Hospital Huddinge, S 14186 Stockholm, Sweden
    Mol Immunol 42:419-23. 2005
    ..In the current article, we discuss the role of 2B4 in the development of adaptive immune responses and the role of NK-T cell interactions in these responses...
  2. ncbi request reprint NK cells stimulate proliferation of T and NK cells through 2B4/CD48 interactions
    Erika Assarsson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Huddinge University Hospital, SE 141 86 Stockholm, Sweden
    J Immunol 173:174-80. 2004
    ....
  3. ncbi request reprint Severe defect in thymic development in an insertional mutant mouse model
    Erika Assarsson
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    J Immunol 178:5018-27. 2007
    ..The Tg66 mice may serve as a useful model to identify genes regulating thymic epithelial cell differentiation, thymic development, and function...
  4. ncbi request reprint 2B4/CD48-mediated regulation of lymphocyte activation and function
    Erika Assarsson
    Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    J Immunol 175:2045-9. 2005
    ..Thus, the 2B4 molecule is more multifunctional than previously understood. In this study, we delineate the current view of 2B4-CD48 interactions among lymphocytes and other cells...
  5. pmc Definition of epitopes and antigens recognized by vaccinia specific immune responses: their conservation in variola virus sequences, and use as a model system to study complex pathogens
    Alessandro Sette
    Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA
    Vaccine 27:G21-6. 2009
    ..Finally, we find that the vast majority of VACV epitopes are conserved in variola virus (VARV), thus suggesting that the epitopes defined herein also have relevance for the efficacy of VACV as a smallpox vaccine...
  6. pmc Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?
    Maya F Kotturi
    Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA
    Immunome Res 5:3. 2009
    ..This limited overlap raised questions about the suitability of using HLA Tg mice as a model system to map human T cell responses to a complex viral pathogen. The present study was designed to investigate this issue in more detail...
  7. pmc TiArA: a virtual appliance for the analysis of Tiling Array data
    Jason A Greenbaum
    Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America
    PLoS ONE 5:e9993. 2010
    ..Genomic tiling arrays have been described in the scientific literature since 2003, yet there is a shortage of user-friendly applications available for their analysis...
  8. ncbi request reprint Cytokine-induced killer T cells kill immature dendritic cells by TCR-independent and perforin-dependent mechanisms
    Pramod S Joshi
    Department of Pathology and Comprehensive Cancer Center, The Ohio State University Medical Center, 129 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210, USA
    J Leukoc Biol 80:1345-53. 2006
    ..Moreover, CIK T cell activation by mDC and their destruction of iDC are independent of the TCR. The cytotoxicity of CIK T cells to iDC is perforin-dependent. Our data have revealed an important regulatory role of CIK cells...
  9. ncbi request reprint A quantitative analysis of the variables affecting the repertoire of T cell specificities recognized after vaccinia virus infection
    Erika Assarsson
    Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA
    J Immunol 178:7890-901. 2007
    ..This suggested that additional factors, including immunoregulatory mechanisms, restrict the repertoire of T cell specificities after vaccinia infection by a factor of at least 10...
  10. ncbi request reprint Memory CD8+ T cells provide an early source of IFN-gamma
    Taku Kambayashi
    Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Immunol 170:2399-408. 2003
    ..Taken together, these results suggest that in response to bacterial and viral products, memory T cells may contribute to innate immunity by providing an early non-Ag-specific source of IFN-gamma...