MICHAEL VAN DOREN JOHNSTON

Summary

Affiliation: Kennedy Krieger Institute
Country: USA

Publications

  1. ncbi request reprint Recent progress in the neurology of learning: memory molecules in the developing brain
    M V Johnston
    Johns Hopkins University School of Medicine and Kennedy Krieger Institute, Baltimore, MD 21205, USA
    J Dev Behav Pediatr 20:50-6. 1999
  2. doi request reprint Diffusion tensor imaging of white matter and developmental outcome
    Michael V Johnston
    Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Departments of Neurology, Pediatrics, and Physical Medicine and Rehabilitation, 707 N Broadway, Baltimore, MD 21205, USA
    Pediatrics 122:656-7. 2008
  3. pmc Plasticity and injury in the developing brain
    Michael V Johnston
    Department of Neurology, Kennedy Krieger Institute and Johns Hopkins University, School of Medicine, 707 North Broadway, Baltimore, MD 21205, USA
    Brain Dev 31:1-10. 2009
  4. pmc Education of a child neurologist: developmental neuroscience relevant to child neurology
    Michael V Johnston
    Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Semin Pediatr Neurol 18:133-8. 2011
  5. ncbi request reprint Sex and the pathogenesis of cerebral palsy
    Michael V Johnston
    Kennedy Krieger Institute and The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Dev Med Child Neurol 49:74-8. 2007
  6. ncbi request reprint Neurobiology of Rett syndrome
    Michael V Johnston
    Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Child Neurol 18:688-92. 2003
  7. ncbi request reprint Clinical disorders of brain plasticity
    Michael V Johnston
    Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, 707 North Broadway, Baltimore, MD 21205, USA
    Brain Dev 26:73-80. 2004
  8. ncbi request reprint Cerebral palsy
    Michael V Johnston
    Kennedy Krieger Institute and Department of Neurology, Johns Hopkins University School of Medicine, 707 North Broadway, Baltimore, MD 21205, USA
    Neuromolecular Med 8:435-50. 2006
  9. ncbi request reprint Models of cerebral palsy: which ones are best?
    Michael V Johnston
    Department of Neurology, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Child Neurol 20:984-7. 2005
  10. ncbi request reprint Rett syndrome and neuronal development
    Michael V Johnston
    Department of Neurology, Kennedy Krieger Institute, Baltimore, MD 21205, USA
    J Child Neurol 20:759-63. 2005

Research Grants

  1. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    Michael Johnston; Fiscal Year: 2005
  2. RESEARCH TRAINING IN BRAIN INJURY REHABILITATION
    Michael Johnston; Fiscal Year: 2007
  3. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    Michael Johnston; Fiscal Year: 2007
  4. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    Michael Johnston; Fiscal Year: 2009
  5. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    Michael Johnston; Fiscal Year: 2001
  6. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    Michael Johnston; Fiscal Year: 1993
  7. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    MICHAEL VAN DOREN JOHNSTON; Fiscal Year: 2010

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Recent progress in the neurology of learning: memory molecules in the developing brain
    M V Johnston
    Johns Hopkins University School of Medicine and Kennedy Krieger Institute, Baltimore, MD 21205, USA
    J Dev Behav Pediatr 20:50-6. 1999
    ..Genetic defects in those pathways appear to be responsible for several human retardation and learning disability syndromes, including Coffin-Lowry syndrome and neurofibromatosis...
  2. doi request reprint Diffusion tensor imaging of white matter and developmental outcome
    Michael V Johnston
    Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Departments of Neurology, Pediatrics, and Physical Medicine and Rehabilitation, 707 N Broadway, Baltimore, MD 21205, USA
    Pediatrics 122:656-7. 2008
  3. pmc Plasticity and injury in the developing brain
    Michael V Johnston
    Department of Neurology, Kennedy Krieger Institute and Johns Hopkins University, School of Medicine, 707 North Broadway, Baltimore, MD 21205, USA
    Brain Dev 31:1-10. 2009
    ..This new information about the molecular pathways involved in brain plasticity and injury are leading to insights that will provide better therapies for pediatric neurological disorders...
  4. pmc Education of a child neurologist: developmental neuroscience relevant to child neurology
    Michael V Johnston
    Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Semin Pediatr Neurol 18:133-8. 2011
    ..This knowledge is increasingly being translated into therapies for previously untreatable disorders...
  5. ncbi request reprint Sex and the pathogenesis of cerebral palsy
    Michael V Johnston
    Kennedy Krieger Institute and The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Dev Med Child Neurol 49:74-8. 2007
    ..This information is relevant to understanding the pathogenesis of CP as well as to the design of future clinical trials of potential neuroprotective strategies...
  6. ncbi request reprint Neurobiology of Rett syndrome
    Michael V Johnston
    Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Child Neurol 18:688-92. 2003
    ..These findings are consistent with other evidence that Rett syndrome disrupts genetic programs that establish and refine synaptic connections...
  7. ncbi request reprint Clinical disorders of brain plasticity
    Michael V Johnston
    Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, 707 North Broadway, Baltimore, MD 21205, USA
    Brain Dev 26:73-80. 2004
    ....
  8. ncbi request reprint Cerebral palsy
    Michael V Johnston
    Kennedy Krieger Institute and Department of Neurology, Johns Hopkins University School of Medicine, 707 North Broadway, Baltimore, MD 21205, USA
    Neuromolecular Med 8:435-50. 2006
    ..Clinical trials indicate that mild hypothermia reduces death or disability in term infants following asphyxia and basic research suggests that this approach might be combined with pharmacological strategies in the future...
  9. ncbi request reprint Models of cerebral palsy: which ones are best?
    Michael V Johnston
    Department of Neurology, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Child Neurol 20:984-7. 2005
  10. ncbi request reprint Rett syndrome and neuronal development
    Michael V Johnston
    Department of Neurology, Kennedy Krieger Institute, Baltimore, MD 21205, USA
    J Child Neurol 20:759-63. 2005
    ..Taken together, this information supports the hypothesis that Rett syndrome is a genetic disorder of synapse development, especially synapses that use glutamate and GABA as neurotransmitters...
  11. ncbi request reprint Excitotoxicity in perinatal brain injury
    Michael V Johnston
    Kennedy Krieger Institute and Department of Neurology, Johns Hopkins University School of Medicine, 707 North Broadway, Baltimore, MD 21205, USA
    Brain Pathol 15:234-40. 2005
    ..Insight into the molecular pathways that mediate perinatal brain injuries could lead to therapeutic interventions...
  12. ncbi request reprint Brain plasticity in paediatric neurology
    Michael V Johnston
    Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Eur J Paediatr Neurol 7:105-13. 2003
    ..Information about these 'plasticity pathways' is useful for understanding their pathophysiology and potential therapy...
  13. ncbi request reprint MRI for neonatal encephalopathy in full-term infants
    Michael V Johnston
    Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Lancet 361:713-4. 2003
  14. ncbi request reprint Possible mechanisms in infants for selective basal ganglia damage from asphyxia, kernicterus, or mitochondrial encephalopathies
    M V Johnston
    Division of Neurology and Developmental Medicine, Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Child Neurol 15:588-91. 2000
    ..This hypothesis has implications for designing neuroprotective therapies and for treating associated chronic movement disorders...
  15. ncbi request reprint Neurobiology of hypoxic-ischemic injury in the developing brain
    M V Johnston
    Division of Neurology and Developmental Medicine and Neuroscience Laboratory, Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Pediatr Res 49:735-41. 2001
    ..The cascade of biochemical and histopathologic events triggered by hypoxic ischemia can extend for days to weeks after the insult is triggered, creating the potential for therapeutic interventions...
  16. ncbi request reprint Developmental disorders of activity dependent neuronal plasticity
    M V Johnston
    Kennedy Krieger Institute and Johns Hopkins University School of Medicine, 707 North Broadway, Baltimore, Maryland 21205, USA
    Indian J Pediatr 68:423-6. 2001
    ..Disruption of neuronal plasticity is a mechanism that may underlie a diverse group of neurodevelopmental disorders...
  17. ncbi request reprint Neurobiology of Rett syndrome: a genetic disorder of synapse development
    M V Johnston
    Kennedy Krieger Institute and Johns Hopkins University, Baltimore, MD 21205, USA
    Brain Dev 23:S206-13. 2001
    ..We hypothesize that a major effect of mutations in the MeCP2 protein is to cause age-related disruption of synaptic proliferation and pruning in the first decade of life...
  18. ncbi request reprint Excitotoxicity in neonatal hypoxia
    M V Johnston
    Division of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, Maryland 21205, USA
    Ment Retard Dev Disabil Res Rev 7:229-34. 2001
    ..Understanding the complex molecular networks triggered by an excitotoxic insult in the neonate provides insight into patterns of selective neuronal vulnerability and potential therapeutic strategies...
  19. ncbi request reprint Mechanisms of hypoxic neurodegeneration in the developing brain
    Michael V Johnston
    Department of Neurology and Pediatrics and Kenedy Kreger Research Institute, John Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Neuroscientist 8:212-20. 2002
    ..Although these molecular changes enhance the developing brain's capacity for plasticity by helping to prune redundant synapses and neurons, they can become "Achilles heels" in the face of a brain energy crisis...
  20. ncbi request reprint Injury and plasticity in the developing brain
    Michael V Johnston
    Department of Neurology and Developmental Medicine, Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Exp Neurol 184:S37-41. 2003
  21. pmc Treatment advances in neonatal neuroprotection and neurointensive care
    Michael V Johnston
    Hugo W Moser Research Institute, at Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Lancet Neurol 10:372-82. 2011
    ..The search is on to discover adjuvant treatments that can further enhance the effects of hypothermia...
  22. doi request reprint Plasticity in the developing brain: implications for rehabilitation
    Michael V Johnston
    Departments of Neurology, Pediatrics and Physical Medicine and Rehabilitation, Kennedy Krieger Institute and Johns Hopkins University School of Medicine, 707 North Broadway, Baltimore, MD 21205, USA
    Dev Disabil Res Rev 15:94-101. 2009
    ..Plasticity is also influenced by genetic factors such as mutations in brain-derived neuronal growth factor. Understanding brain plasticity provides a basis for developing better therapies to improve outcome from acquired brain injuries...
  23. pmc Gabapentin neuroprotection and seizure suppression in immature mouse brain ischemia
    Beatrix S Traa
    Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, Maryland 21205, USA
    Pediatr Res 64:81-5. 2008
    ..When analyzed by animal sex, the data suggest that gabapentin may more effectively reduce acute seizures and injury in male pups vs. female pups...
  24. pmc Impact of age and strain on ischemic brain injury and seizures after carotid ligation in immature mice
    Anne M Comi
    Hugo W Moser Research Institute at Kennedy Krieger, Baltimore, MD 21205, USA
    Int J Dev Neurosci 27:271-7. 2009
    ..We also found that the age at which ligation is performed and genetic strain have a strong influence on the severity of injury...
  25. ncbi request reprint Strain variability, injury distribution, and seizure onset in a mouse model of stroke in the immature brain
    Anne M Comi
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Dev Neurosci 27:127-33. 2005
    ....
  26. ncbi request reprint A new model of stroke and ischemic seizures in the immature mouse
    Anne M Comi
    Department of Neurology, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Pediatr Neurol 31:254-7. 2004
    ..This new model should be useful for examining the pathogenesis of stroke in the immature brain and the potential contribution of seizures to final outcome...
  27. ncbi request reprint Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress
    Yasushi Teshima
    Institute of Molecular Cardiobiology, The Johns Hopkins University, Baltimore, MD 21205, USA
    Stroke 34:1796-802. 2003
    ..However, the precise mechanisms of this protection are not well established. We hypothesized that mitoK(ATP) channel openers prevent apoptosis by preserving mitochondrial membrane potential...
  28. pmc Chronic brain injury and behavioral impairments in a mouse model of term neonatal strokes
    Shilpa D Kadam
    Department of Neurology and Developmental Medicine, Hugo W Moser Research Institute at Kennedy Krieger, Baltimore, MD 21205, USA
    Behav Brain Res 197:77-83. 2009
    ..Overall, our results demonstrate that ischemia induced by our neonatal stroke model produces behavioral deficits that are consistent with the brain injury...
  29. ncbi request reprint Dextromethorphan protects male but not female mice with brain ischemia
    Anne M Comi
    Departments of aNeurology and Developmental Medicine bNeuroscience, Kennedy Krieger Research Institute Departments of cNeurology dPediatrics eNeuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Neuroreport 17:1319-22. 2006
    ..These results suggest that dextromethorphan neuroprotection against ischemic injury in the immature brain is sex-dependent...
  30. pmc Sensory and motor deficits in children with cerebral palsy born preterm correlate with diffusion tensor imaging abnormalities in thalamocortical pathways
    Alexander H Hoon
    Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD 21205, USA
    Dev Med Child Neurol 51:697-704. 2009
    ..We investigated the relationship between DTI-observed thalamocortical (posterior thalamic radiation) injury, motor (corticospinal tract) injury, and sensorimotor function...
  31. ncbi request reprint Neonatal electrolytic lesions of the basal forebrain stunt plasticity in mouse barrel field cortex
    Akira Nishimura
    Neuroscience Laboratory, The Kennedy Krieger Research Institute, 707 North Broadway, Baltimore, MD 21205, USA
    Int J Dev Neurosci 20:481-9. 2002
    ..Cortex 8 (1998) 63]. These results suggest that cholinergic inputs play a role in regulating plasticity as well as in the morphogenesis of mouse sensory-motor cortex...
  32. ncbi request reprint Protective effect of erythropoietin in neonatal hypoxic ischemia in mice
    Hiroko Matsushita
    Kennedy Krieger Research and Johns Hopkins School of medicine, Baltimore, MD 21205, USA
    Neuroreport 14:1757-61. 2003
    ..To our knowledge, this is the first report demonstrating persistent neuroprotective effects of erythropoietin in neonatal mice...
  33. doi request reprint Neural stem cells reduce brain injury after unilateral carotid ligation
    Anne M Comi
    Division of Neurology and Developmental Medicine, Kennedy Krieger Institute, and Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    Pediatr Neurol 38:86-92. 2008
    ..Neural stem cells have the potential to ameliorate ischemic injury in the immature brain, although tumor development is a serious concern...
  34. ncbi request reprint Clinical variability in Rett syndrome
    Sakkubai Naidu
    Department of Neurogenetics, Kennedy Krieger Institute, Baltimore, MD 21205, USA
    J Child Neurol 18:662-8. 2003
    ....
  35. ncbi request reprint Minocycline worsens hypoxic-ischemic brain injury in a neonatal mouse model
    Masahiro Tsuji
    Kennedy Krieger Research Institute, Baltimore, MD 21205, USA
    Exp Neurol 189:58-65. 2004
    ..However, it is important to examine this drug carefully before clinical use in human infants, taking our data in the mouse model into consideration...
  36. ncbi request reprint Immature mouse unilateral carotid ligation model of stroke
    Anne M Comi
    Department of Neurology, Kennedy Krieger Institute, Johns Hopkins University, Baltomore, MD 21205, USA
    J Child Neurol 20:980-3. 2005
    ..In addition, more work is needed to delineate the long-term consequences of the insult in this new model...
  37. ncbi request reprint Noninvasive assessment of brain injury in a canine model of hypothermic circulatory arrest using magnetic resonance spectroscopy
    Christopher J Barreiro
    Division of Cardiac Surgery, Kennedy Krieger Research Institute, Baltimore, Maryland, USA
    Ann Thorac Surg 81:1593-8. 2006
    ..We demonstrated that noninvasive measurement of NAA:Cho with magnetic resonance spectroscopy facilitates assessment of neuronal injury after HCA and allows for evaluation of neuroprotective strategies...
  38. ncbi request reprint Valproic acid prevents brain injury in a canine model of hypothermic circulatory arrest: a promising new approach to neuroprotection during cardiac surgery
    Jason A Williams
    Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Kennedy Krieger Institute, Baltimore, Maryland, USA
    Ann Thorac Surg 81:2235-41; discussion 2241-2. 2006
    ..We used valproate in our canine model of hypothermic circulatory arrest to evaluate its neuroprotective benefit in complex cardiac surgical cases...
  39. pmc Alpha II-spectrin breakdown products serve as novel markers of brain injury severity in a canine model of hypothermic circulatory arrest
    Eric S Weiss
    Division of Cardiac Surgery, Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Ann Thorac Surg 88:543-50. 2009
    ..We measured cerebrospinal fluid alpha II-spectrin breakdown products (alphaII-SBDPs) in a canine model of hypothermic circulatory arrest (HCA) and cardiopulmonary bypass...
  40. pmc Hypoxic-ischemic encephalopathy in the term infant
    Ali Fatemi
    Kennedy Krieger Institute, Department of Neurology, Johns Hopkins Medical Institutions, 707 N Broadway, Baltimore, MD 21205, USA
    Clin Perinatol 36:835-58, vii. 2009
    ..Despite all these advances, therapeutic interventions are still limited. In this article the authors discuss several molecular pathways involved in hypoxia-ischemia, and potential therapeutic targets...
  41. ncbi request reprint MeCP2 expression and function during brain development: implications for Rett syndrome's pathogenesis and clinical evolution
    Walter E Kaufmann
    Center for Genetic Disorders of Cognition and Behavior, Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, MD 21211, USA
    Brain Dev 27:S77-S87. 2005
    ..Two models are proposed for explaining general and regional neuronal abnormalities in RTT and the phenotypical outcome of MeCP2 dysfunction, respectively...
  42. pmc Glutamate excitotoxicity mediates neuronal apoptosis after hypothermic circulatory arrest
    Elaine E Tseng
    Division of Cardiac Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Ann Thorac Surg 89:440-5. 2010
    ..This study was undertaken to determine whether glutamate receptor antagonism reduces nitric oxide formation and neuronal apoptosis after hypothermic circulatory arrest...
  43. pmc Ischemic stroke in children with critical illness: a poor prognostic sign
    Lori C Jordan
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Pediatr Neurol 36:244-6. 2007
    ..Mortality resulted primarily from the underlying illness. Prognosis after stroke is markedly worsened in children with premorbid critical illness...
  44. ncbi request reprint Activity-dependent expression of Egr1 mRNA in somatosensory cortex of developing rats
    Ramesh C Patra
    Kennedy Krieger Research Institute, Baltimore, Maryland 21205, USA
    J Neurosci Res 78:235-44. 2004
    ....
  45. ncbi request reprint Oral baclofen in cerebral palsy: possible seizure potentiation?
    Donna E Hansel
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Pediatr Neurol 29:203-6. 2003
    ..Further study of the effects of baclofen on seizures is warranted...
  46. pmc Hawley H. Seiler Resident Award. Transcriptional profile of brain injury in hypothermic circulatory arrest and cardiopulmonary bypass
    Jeremiah G Allen
    Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Ann Thorac Surg 89:1965-71. 2010
    ..Canine genome sequencing allows profiling of genomic changes after HCA and CPB alone. We hypothesize that gene regulation will increase with increased severity of injury...
  47. ncbi request reprint Brain glucose metabolism in Rett Syndrome
    Patricia M Villemagne
    Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 0807, USA
    Pediatr Neurol 27:117-22. 2002
    ..This pattern differs from those described in Down syndrome, autism, and Alzheimer's disease...
  48. ncbi request reprint Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia
    David J Caparrelli
    Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Ann Thorac Surg 74:838-44; discussion 844-5. 2002
    ..We hypothesized that similar endogenous mechanisms exist in the spinal cord and that diazoxide, a potent mitoKATP opener, could reduce neurologic injury after aortic cross-clamping in a model of spinal cord ischemia...
  49. doi request reprint Aicardi syndrome mimicking intrauterine hydrocephalus
    Deivasumathy Muthugovindan
    Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Brain Dev 31:638-40. 2009
    ..Aicardi syndrome most commonly comes to medical attention because of seizures later in infancy...
  50. ncbi request reprint PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury
    Henrik Hagberg
    Perinatal Center, Sahlgrenska University Hospital, Goteborg, Sweden
    J Neurochem 90:1068-75. 2004
    ..The results indicate that hypoxia-ischemia activates Poly(ADP-ribose) polymerase-1 in the neonatal brain and that the sex of the animal strongly influences its role in the pathogenesis of brain injury...
  51. ncbi request reprint Gene expression profiling: a new tool for pediatric neurology?
    Michael V Johnston
    Curr Opin Neurol 18:89-90. 2005
  52. ncbi request reprint Fresh ideas for treating developmental cognitive disorders
    Michael V Johnston
    Curr Opin Neurol 19:115-8. 2006
  53. doi request reprint Invited article: Residency Review Committee for neurology: structure and function
    Ronald Kanner
    Albert Einstein College of Medicine, New Hyde Park, NY, USA
    Neurology 71:452-6. 2008
  54. ncbi request reprint Congenital heart disease and brain injury
    Michael V Johnston
    N Engl J Med 357:1971-3. 2007
  55. ncbi request reprint Global gene expression in the developing rat brain after hypoxic preconditioning: involvement of apoptotic mechanisms?
    Malin Gustavsson
    Department of Physiology, Sahlgrenska Academy, Goteborg University, Goteborg, Sweden
    Pediatr Res 61:444-50. 2007
    ....
  56. ncbi request reprint Pilot study to determine the hemodynamic safety and feasibility of magnesium sulfate infusion in children with severe traumatic brain injury
    Joanne E Natale
    Research Center for Genetic Medicine, Children s National Medical Center, Washington, DC, USA
    Pediatr Crit Care Med 8:1-9. 2007
    ....
  57. ncbi request reprint Vascular response to hypoxic preconditioning in the immature brain
    Malin Gustavsson
    Perinatal Center, Department of Physiology, Sahlgrenska Academy, Goteborg University, Goteborg, Sweden
    J Cereb Blood Flow Metab 27:928-38. 2007
    ..In conclusion, hypoxic PC upregulates vascular genes, increases vascular density and attenuates the decrease of CBF during a subsequent HI, which could contribute to tolerance...

Research Grants21

  1. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    Michael Johnston; Fiscal Year: 2005
    ..These studies are important for developing practical ways to salvage brain tissue in infants and young children who have suffered hypoxic-ischemic injuries. ..
  2. RESEARCH TRAINING IN BRAIN INJURY REHABILITATION
    Michael Johnston; Fiscal Year: 2007
    ..A weekly series of seminars, rounds, lectures and didactic course work brings together trainees to learn core information about neurorehabilitation in children. ..
  3. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    Michael Johnston; Fiscal Year: 2007
    ..Detailed information about the molecular pathways that mediate cell death from hypoxia-ischemia is critically important for developing and testing neuroprotective interventions. ..
  4. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    Michael Johnston; Fiscal Year: 2009
    ..Detailed information about the molecular pathways that mediate cell death from hypoxia-ischemia is critically important for developing and testing neuroprotective interventions. ..
  5. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    Michael Johnston; Fiscal Year: 2001
    ..The information gained from these experiments is very important for developing practical neuroprotective therapies for fetuses, infants and young children. ..
  6. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    Michael Johnston; Fiscal Year: 1993
  7. NEUROTRANSMITTER INJURY MECHANISMS IN DEVELOPING BRAIN
    MICHAEL VAN DOREN JOHNSTON; Fiscal Year: 2010
    ..Detailed information about the molecular pathways that mediate cell death from hypoxia-ischemia is critically important for developing and testing neuroprotective interventions. ..