Leon H Kircik

Summary

Affiliation: Kathleen D. Schaum and Associates
Country: USA

Publications

  1. ncbi request reprint Utilization of narrow-band ultraviolet light B therapy and etanercept for the treatment of psoriasis (UNITE): efficacy, safety, and patient-reported outcomes
    Leon Kircik
    Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, USA
    J Drugs Dermatol 7:245-53. 2008
  2. ncbi request reprint A nonsteroidal lamellar matrix cream containing palmitoylethanolamide for the treatment of atopic dermatitis
    Leon Kircik
    Indiana University, Indianapolis, IN, USA
    J Drugs Dermatol 9:334-8. 2010
  3. ncbi request reprint Doxycycline and minocycline for the management of acne: a review of efficacy and safety with emphasis on clinical implications
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY, USA
    J Drugs Dermatol 9:1407-11. 2010
  4. ncbi request reprint Harnessing the anti-inflammatory effects of topical dapsone for management of acne
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY, USA
    J Drugs Dermatol 9:667-71. 2010
  5. ncbi request reprint Salicylic Acid 6% in an ammonium lactate emollient foam vehicle in the treatment of mild-to-moderate scalp psoriasis
    Leon Kircik
    Physicians Skin Care, Louisville, KY, USA
    J Drugs Dermatol 10:270-3. 2011
  6. ncbi request reprint Topical calcipotriene 0.005% and betamethasone dipropionate 0.064% maintains efficacy of etanercept after step-down dose in patients with moderate-to-severe plaque psoriasis: results of an open label trial
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY and bIndiana University School of Medicine, Indianapolis, IN, USA
    J Drugs Dermatol 10:878-82. 2011
  7. ncbi request reprint Efficacy and safety of topical calcitriol 3 microg/g ointment, a new topical therapy for chronic plaque psoriasis
    Leon Kircik
    Indiana University School of Medicine, Louisville, KY, USA
    J Drugs Dermatol 8:s9-16. 2009
  8. ncbi request reprint Scalp psoriasis
    Leon H Kircik
    Mount Sinai Medical Center, NewYork, NY, USA
    J Drugs Dermatol 9:s101-5. 2010
  9. ncbi request reprint Tretinoin microsphere gel pump 0.04% versus tazarotene cream 0.05% in the treatment of mild-to-moderate facial acne vulgaris
    Leon H Kircik
    Mount Sinai School of Medicine, New York, NY, USA
    J Drugs Dermatol 8:650-4. 2009
  10. ncbi request reprint Comparative efficacy and safety results of two topical combination acne regimens
    Leon H Kircik
    Mount Sinai School of Medicine, New York, NY, USA
    J Drugs Dermatol 8:624-30. 2009

Detail Information

Publications33

  1. ncbi request reprint Utilization of narrow-band ultraviolet light B therapy and etanercept for the treatment of psoriasis (UNITE): efficacy, safety, and patient-reported outcomes
    Leon Kircik
    Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, USA
    J Drugs Dermatol 7:245-53. 2008
    ..Etanercept and narrow-band ultraviolet light B (NB-UVB) are widely used to treat this disease...
  2. ncbi request reprint A nonsteroidal lamellar matrix cream containing palmitoylethanolamide for the treatment of atopic dermatitis
    Leon Kircik
    Indiana University, Indianapolis, IN, USA
    J Drugs Dermatol 9:334-8. 2010
    ....
  3. ncbi request reprint Doxycycline and minocycline for the management of acne: a review of efficacy and safety with emphasis on clinical implications
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY, USA
    J Drugs Dermatol 9:1407-11. 2010
    ....
  4. ncbi request reprint Harnessing the anti-inflammatory effects of topical dapsone for management of acne
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY, USA
    J Drugs Dermatol 9:667-71. 2010
    ..Data suggest the vehicle formulation enhances healing and contributes to tolerability, making topical dapsone 5% gel a worthwhile anti-inflammatory treatment for many patients with mild-to-moderate acne vulgaris...
  5. ncbi request reprint Salicylic Acid 6% in an ammonium lactate emollient foam vehicle in the treatment of mild-to-moderate scalp psoriasis
    Leon Kircik
    Physicians Skin Care, Louisville, KY, USA
    J Drugs Dermatol 10:270-3. 2011
    ..Salicylic acid 6% emollient foam provides a useful option in the treatment of psoriasis that is highly effective, well tolerated and acceptable to patients...
  6. ncbi request reprint Topical calcipotriene 0.005% and betamethasone dipropionate 0.064% maintains efficacy of etanercept after step-down dose in patients with moderate-to-severe plaque psoriasis: results of an open label trial
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY and bIndiana University School of Medicine, Indianapolis, IN, USA
    J Drugs Dermatol 10:878-82. 2011
    ..005% and betamethasone dipropionate 0.064% combination ointment, approved for the treatment of psoriasis, to sustain the original efficacy of etanercept by augmenting response to the 50 mg/week SC dose, thus stabilizing the disease...
  7. ncbi request reprint Efficacy and safety of topical calcitriol 3 microg/g ointment, a new topical therapy for chronic plaque psoriasis
    Leon Kircik
    Indiana University School of Medicine, Louisville, KY, USA
    J Drugs Dermatol 8:s9-16. 2009
    ..Calcitriol ointment offers considerable flexibility for use in a variety of monotherapy and combination therapy regimens for patients with psoriasis...
  8. ncbi request reprint Scalp psoriasis
    Leon H Kircik
    Mount Sinai Medical Center, NewYork, NY, USA
    J Drugs Dermatol 9:s101-5. 2010
    ..05%, and reports that CP shampoo is safe and efficacious in the long-term management of scalp psoriasis. A new foam formulation of coal tar is shown to be cosmetically acceptable and easier to apply...
  9. ncbi request reprint Tretinoin microsphere gel pump 0.04% versus tazarotene cream 0.05% in the treatment of mild-to-moderate facial acne vulgaris
    Leon H Kircik
    Mount Sinai School of Medicine, New York, NY, USA
    J Drugs Dermatol 8:650-4. 2009
    ..1875). Skin dryness, peeling and pruritus were significantly less in the TMG PUMP group as early as week 4. Adverse events related to study treatment were rare in both groups and all resolved upon discontinuation of study medication...
  10. ncbi request reprint Comparative efficacy and safety results of two topical combination acne regimens
    Leon H Kircik
    Mount Sinai School of Medicine, New York, NY, USA
    J Drugs Dermatol 8:624-30. 2009
    ..While both regimens were safe and effective, regimen BPO/C+RAM yielded a more rapid onset of effect versus regimen CPT+BPO against both non-inflammatory and inflammatory lesions. Both treatment regimens were well-tolerated...
  11. ncbi request reprint Treatment of moderate to severe plaque psoriasis with concomitant efalizumab and narrow-band ultraviolet B phototherapy
    Leon H Kircik
    Department of Dermatology, Indiana University Medical Center, Indianapolis, IN, USA
    J Drugs Dermatol 7:947-52. 2008
    ..Efalizumab therapy and narrow-band ultraviolet B (NB-UVB) phototherapy have different mechanisms of action; combined therapy may be more effective than either treatment alone in treating moderate to severe plaque psoriasis...
  12. ncbi request reprint Safety of a novel gel formulation of clindamycin phosphate 1.2%-tretinoin 0.025%: results from a 52-week open-label study
    Leon H Kircik
    Indiana University School of Medicine, Indianapolis, USA
    Cutis 82:358-66. 2008
    ..The CLIN/RA gel fixed-dose combination provided minimal adverse events and a favorable safety profile for 2 agents with established efficacy for the treatment of acne vulgaris...
  13. ncbi request reprint Optimizing topical therapies for treating psoriasis: a consensus conference
    Joshua A Zeichner
    Mount Sinai Medical Center, New York, New York, USA
    Cutis 86:5-31; quiz 32. 2010
    ..Therapeutic considerations also should focus on adherence, improving QOL, and promoting a good patient-physician relationship...
  14. ncbi request reprint Comparative study of the efficacy and tolerability of a unique topical scar product vs white petrolatum following shave biopsies
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY, USA
    J Drugs Dermatol 12:86-90. 2013
    ..This scar product may be useful in hastening the healing of cutaneous shave biopsies and reducing the stinging/burning and itching associated with the normal healing process...
  15. ncbi request reprint Treatment of mild-to-moderate chronic hand dermatitis with clobetasol propionate 0.05% EF foam: results from an open-label study
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY, USA
    J Drugs Dermatol 10:1398-402. 2011
    ..To assess the safety and efficacy of clobetasol propionate 0.05% emulsion formulation (EF) foam in subjects with mild-to-moderate chronic hand dermatitis...
  16. ncbi request reprint Safety and efficacy of two anti-acne/anti-aging treatments in subjects with photodamaged skin and mild to moderate acne vulgaris
    Leon H Kircik
    Physicians Skin Care, PLLC, Louiseville, KY 40217, USA
    J Drugs Dermatol 11:737-40. 2012
    ..The novel, non-prescription formulation includes several ingredients shown to target factors underlying the pathogenesis of acne vulgaris while also addressing multiple components in the pathophysiology of skin aging...
  17. ncbi request reprint Histologic improvement in photodamage after 12 months of treatment with tretinoin emollient cream (0.02%)
    Leon H Kircik
    Physicians Skin Care, PLLC, Louisville, KY 40217, USA
    J Drugs Dermatol 11:1036-40. 2012
    ..02% for the treatment of moderate to severe facial photodamage...
  18. ncbi request reprint Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: a 16-week, baseline-controlled study
    Leon H Kircik
    Indiana University School of Medicine, Indianapolis, IN, USA
    J Drugs Dermatol 10:586-90. 2011
    ..This pilot study demonstrates the efficacy of topical AzA gel 15% when applied twice daily for the reduction of both acne and PIH. J..
  19. ncbi request reprint Anti-TNF agents for the treatment of psoriasis
    Leon H Kircik
    Indiana University Medical Center, Indianapolis, Indiana, USA
    J Drugs Dermatol 8:546-59. 2009
    ..Treatment strategies--which include topical treatment, phototherapy, methtrexate, cyclosporine and acitretin--also encompass several biologic agents that target immune mediators associated with the condition...
  20. ncbi request reprint Clocortolone pivalate: a topical corticosteroid with a unique structure
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY, USA
    J Drugs Dermatol 12:s3-4. 2013
    ..Clocortolone pivalate 0.1% cream is a well-formulated and versatile therapeutic option to consider for many of our patients with steroid-responsive dermatoses...
  21. ncbi request reprint The treatment of inflammatory facial dermatoses with topical corticosteroids: focus on clocortolone pivalate 0.1% cream
    Leon H Kircik
    Indiana University School of Medicine, Indianapolis, IN, USA
    J Drugs Dermatol 11:1194-8. 2012
    ....
  22. ncbi request reprint Transepidermal water loss (TEWL) and corneometry with hydrogel vehicle in the treatment of atopic dermatitis: a randomized, investigator-blind pilot study
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY, USA
    J Drugs Dermatol 11:180-4. 2012
    ....
  23. ncbi request reprint Safety and efficacy evaluation of tretinoin cream 0.02% for the reduction of photodamage: a pilot study
    Leon H Kircik
    Mount Sinai Medical Center, New York, NY, USA
    J Drugs Dermatol 11:83-90. 2012
    ..Clinical studies as well as histologic data maintain that tretinoin improves the appearance of photodamage; however, the long-term benefits of tretinoin 0.02% in moderate to severe photodamage have not been established...
  24. ncbi request reprint Importance of vehicles in acne therapy
    Leon H Kircik
    Indiana University School of Medicine, Indianapolis, IN, USA
    J Drugs Dermatol 10:s17-23. 2011
    ....
  25. ncbi request reprint Efficacy and tolerability of retapamulin 1% ointment for the treatment of infected atopic dermatitis: a pilot study
    Leon H Kircik
    Physicians Skin Care, PLLC, Louisville, KY 40217, USA
    J Drugs Dermatol 11:858-60. 2012
    ..Retapamulin 1% ointment is a unique topical antibiotic formulation that may be a suitable option for the treatment of clinically infected AD...
  26. ncbi request reprint Observational evaluation of sertaconazole nitrate cream 2% in the treatment of pruritus related to tinea pedis
    Leon H Kircik
    Mount Sinai Medical Center, New York, New York, USA
    Cutis 84:279-83. 2009
    ..Furthermore, early and rapid relief of symptoms, as seen in this study, may encourage patients to continue therapy for the full recommended period of 4 to 6 weeks, thereby reducing the risk for relapse that leads to chronic disease...
  27. doi request reprint An open-label, single-center pilot study to determine the antifungal activity of a new nonsteroidal cream (Promiseb Topical Cream) after 7 days of use in healthy volunteers
    Leon Kircik
    Department of Dermatology, Indiana University Medical Center, Bloomington, IN 47405 7000, USA
    Clin Dermatol 27:S44-7. 2009
    ..03). This pilot study shows the nonsteroidal topical cream has antifungal activities. Further exploration into its potential as a therapeutic alternative for seborrheic dermatitis is warranted...
  28. ncbi request reprint Study of trolamine-containing topical emulsion for wound healing after shave biopsy
    Leon H Kircik
    Mount Sinai Medical Center, New York, New York, USA
    Cutis 83:326-32. 2009
    ..These data indicate that 4 weeks of treatment with trolamine-containing topical emulsion promotes rapid healing and is safe and well-tolerated in patients who undergo shave biopsies...
  29. ncbi request reprint Use of etanercept for psoriatic arthritis in the dermatology clinic: the Experience Diagnosing, Understanding Care, and Treatment with Etanercept (EDUCATE) study
    Alice B Gottlieb
    Department of Dermatology, Tufts New England Medical Center, Boston, MA 02111 1533, USA
    J Dermatolog Treat 17:343-52. 2006
    ..To assess the efficacy and tolerability of etanercept to treat psoriatic arthritis...
  30. ncbi request reprint Community-based trial results of combination clindamycin 1%--benzoyl peroxide 5% topical gel plus tretinoin microsphere gel 0.04% or 0.1% or adapalene gel 0.1% in the treatment of moderate to severe acne
    Leon Kircik
    Indiana University, Indianapolis, USA
    Cutis 80:10-4. 2007
    ..This study investigated the efficacy and safety of combination therapy with clindamycin 1%-BPO 5% topical gel plus tretinoin microsphere (RAM) gel 0.04% or 0.1% or adapalene (AP) gel 0.1% in moderate to severe acne...
  31. ncbi request reprint Comparative efficacy and safety results of topical hemostatic powder and sterile compressed foam sponge in second intention healing following Mohs micrographic surgery
    Leon Kircik
    Indiana University, Indianapolis, IN, USA
    J Drugs Dermatol 9:137-40. 2010
    ..By week 12, wound size was reduced by a median of 182 mm2 in group 1 and 161.5 mm2 in group 2. A case series of subjects treated with THP following 4-mm punch biopsies is also discussed...
  32. ncbi request reprint The evolving role of therapeutic shampoos for targeting symptoms of inflammatory scalp disorders
    Leon Kircik
    Physicians Skin Care, Louisville, KY 40217, USA
    J Drugs Dermatol 9:41-8. 2010
    ..These findings suggest that high-potency corticosteroid shampoos may provide an important option for topical corticosteroid therapy in dermatologic conditions affecting the scalp...
  33. ncbi request reprint A novel hydrogel vehicle formulated for the treatment of atopic dermatitis
    Leon Kircik
    Indiana University School of Medicine, Madison, IN, USA
    J Drugs Dermatol 6:718-22. 2007
    ..Patient and physician preference surveys suggest that the novel properties of this vehicle may aid in patient compliance with AD therapy...