Ruth Welti

Summary

Affiliation: Kansas State University
Country: USA

Publications

  1. ncbi request reprint Plant lipidomics: discerning biological function by profiling plant complex lipids using mass spectrometry
    Ruth Welti
    Kansas Lipidomics Research Center, Division of Biology, Kansas State University, Manhattan, KS 66506, USA
    Front Biosci 12:2494-506. 2007
  2. ncbi request reprint Profiling membrane lipids in plant stress responses. Role of phospholipase D alpha in freezing-induced lipid changes in Arabidopsis
    Ruth Welti
    Division of Biology, Ackert Hall, Kansas State University, Manhattan, Kansas 66506, USA
    J Biol Chem 277:31994-2002. 2002
  3. ncbi request reprint Electrospray ionization tandem mass spectrometry scan modes for plant chloroplast lipids
    Ruth Welti
    Division of Biology, Kansas State University, Ackert Hall, Manhattan, KS 66506 4901, USA
    Anal Biochem 314:149-52. 2003
  4. pmc Direct infusion mass spectrometry of oxylipin-containing Arabidopsis membrane lipids reveals varied patterns in different stress responses
    Hieu Sy Vu
    Kansas Lipidomics Research Center, Division of Biology, Kansas State University, Manhattan, Kansas 66506, USA
    Plant Physiol 158:324-39. 2012
  5. ncbi request reprint The plasma membrane-bound phospholipase Ddelta enhances freezing tolerance in Arabidopsis thaliana
    Weiqi Li
    Department of Biochemistry, Kansas State University, Manhattan, Kansas 66506 3702, USA
    Nat Biotechnol 22:427-33. 2004
  6. ncbi request reprint Rapid characterization of the fatty acyl composition of complex lipids by collision-induced dissociation time-of-flight mass spectrometry
    Steven Wynn Esch
    Kansas Lipidomics Research Center, Division of Biology, Kansas State University, Manhattan, KS 66506, USA
    J Lipid Res 48:235-41. 2007
  7. ncbi request reprint Quantitative profiling of polar glycerolipid species from organs of wild-type Arabidopsis and a phospholipase Dalpha1 knockout mutant
    Shivakumar Pattada Devaiah
    Department of Biochemistry, Kansas State University, Manhattan, KS 66506, USA
    Phytochemistry 67:1907-24. 2006
  8. pmc Wounding stimulates the accumulation of glycerolipids containing oxophytodienoic acid and dinor-oxophytodienoic acid in Arabidopsis leaves
    Christen M Buseman
    Division of Biology, Kansas State University, Manhattan, 66506, USA
    Plant Physiol 142:28-39. 2006
  9. pmc Suppression of phospholipase Dγs confers increased aluminum resistance in Arabidopsis thaliana
    Jian Zhao
    Department of Biochemistry, Kansas State University, Manhattan, Kansas, United States of America
    PLoS ONE 6:e28086. 2011
  10. pmc Enhanced seed viability and lipid compositional changes during natural ageing by suppressing phospholipase Dα in soybean seed
    Junghoon Lee
    Department of Plant Pathology, Kansas State University, Manhattan, KS, USA
    Plant Biotechnol J 10:164-73. 2012

Collaborators

  • Jyoti Shah
  • Xuemin Wang
  • Jian Zhao
  • Gerald H Lushington
  • Kathrin Schrick
  • Ivan Baxter
  • Eric Maréchal
  • C B Rajashekar
  • Junping Chen
  • Sherry D Fleming
  • Cunxi Wang
  • Lloyd W Sumner
  • Marie Laure Fauconnier
  • Mee Len Chye
  • Ping Ouyang
  • Kent D Chapman
  • John K Zehmer
  • D DellaPenna
  • F F Hsu
  • Mary R Roth
  • Maoyin Li
  • Pamela Tamura
  • Xiangqing Pan
  • Giorgis Isaac
  • Junghoon Lee
  • Todd D Williams
  • Ashis Nandi
  • Shivakumar P Devaiah
  • Sunitha Shiva
  • Hieu Sy Vu
  • Steven Wynn Esch
  • Weiqi Li
  • Sara Maatta
  • Mary Roth
  • Ratnesh Chaturvedi
  • Richard Jeannotte
  • Yueyun Hong
  • Alexis A Sparks
  • Dongwon Kim
  • Christen M Buseman
  • Thilani Samarakoon
  • Harold N Trick
  • William T Schapaugh
  • Wenhua Zhang
  • Byron L Sparkes
  • Hiroshi Maeda
  • Cyrille Botté
  • Michael L Fitzgerald
  • Rene Bartz
  • Wenyu Yang
  • Shivakumar Pattada Devaiah
  • Kartikeya Krothapalli
  • Chunbo Qin
  • Zhenguo Zhou
  • Daya Sagar Nune
  • Mahesh Visvanathan
  • William W Bockus
  • Shantan Reddy Marepally
  • Nadezhda A Galeva
  • Jiarui Li
  • Kaleb Lowe
  • Brad Scheu
  • Emily E Archer Slone
  • Ernest Mui
  • Rima McLeod
  • Nadia Saïdani
  • Marie France Cesbron-Delauw
  • Monica Mondragon
  • Tammy L Sage
  • Ruiping Wang
  • Henri Vial
  • Ragiba Makandar
  • Jean Francois Dubremetz
  • Corinne Mercier
  • Lixia Li
  • Ricardo Mondragon
  • Barney Venables
  • Naifang Lu
  • Susan A Bell
  • Pingsheng Liu
  • Cari E Brown
  • Brian Seed
  • Mary McKee
  • Richard G W Anderson
  • Debbie Z Zhuang
  • Julie L Goss
  • Wen Hong Li
  • Ernst Heinz
  • Ramnik Xavier
  • Mason W Freeman

Detail Information

Publications41

  1. ncbi request reprint Plant lipidomics: discerning biological function by profiling plant complex lipids using mass spectrometry
    Ruth Welti
    Kansas Lipidomics Research Center, Division of Biology, Kansas State University, Manhattan, KS 66506, USA
    Front Biosci 12:2494-506. 2007
    ..Such lipidomic analyses have been used to uncover roles for lipids in plant response to stresses and to identify in vivo functions of genes involved in lipid metabolism...
  2. ncbi request reprint Profiling membrane lipids in plant stress responses. Role of phospholipase D alpha in freezing-induced lipid changes in Arabidopsis
    Ruth Welti
    Division of Biology, Ackert Hall, Kansas State University, Manhattan, Kansas 66506, USA
    J Biol Chem 277:31994-2002. 2002
    ....
  3. ncbi request reprint Electrospray ionization tandem mass spectrometry scan modes for plant chloroplast lipids
    Ruth Welti
    Division of Biology, Kansas State University, Ackert Hall, Manhattan, KS 66506 4901, USA
    Anal Biochem 314:149-52. 2003
  4. pmc Direct infusion mass spectrometry of oxylipin-containing Arabidopsis membrane lipids reveals varied patterns in different stress responses
    Hieu Sy Vu
    Kansas Lipidomics Research Center, Division of Biology, Kansas State University, Manhattan, Kansas 66506, USA
    Plant Physiol 158:324-39. 2012
    ..These data form the basis for a working hypothesis that the stress-specific signatures of ox-lipids, like those of oxylipins, are indicative of their functions...
  5. ncbi request reprint The plasma membrane-bound phospholipase Ddelta enhances freezing tolerance in Arabidopsis thaliana
    Weiqi Li
    Department of Biochemistry, Kansas State University, Manhattan, Kansas 66506 3702, USA
    Nat Biotechnol 22:427-33. 2004
    ....
  6. ncbi request reprint Rapid characterization of the fatty acyl composition of complex lipids by collision-induced dissociation time-of-flight mass spectrometry
    Steven Wynn Esch
    Kansas Lipidomics Research Center, Division of Biology, Kansas State University, Manhattan, KS 66506, USA
    J Lipid Res 48:235-41. 2007
    ..Good precision is obtained when data are acquired for approximately 1 min per sample...
  7. ncbi request reprint Quantitative profiling of polar glycerolipid species from organs of wild-type Arabidopsis and a phospholipase Dalpha1 knockout mutant
    Shivakumar Pattada Devaiah
    Department of Biochemistry, Kansas State University, Manhattan, KS 66506, USA
    Phytochemistry 67:1907-24. 2006
    ....
  8. pmc Wounding stimulates the accumulation of glycerolipids containing oxophytodienoic acid and dinor-oxophytodienoic acid in Arabidopsis leaves
    Christen M Buseman
    Division of Biology, Kansas State University, Manhattan, 66506, USA
    Plant Physiol 142:28-39. 2006
    ..The rapid accumulation of high levels of galactolipid species containing OPDA-OPDA and OPDA-dnOPDA in wounded leaves is consistent with these lipids being the primary products of plastidic oxylipin biosynthesis...
  9. pmc Suppression of phospholipase Dγs confers increased aluminum resistance in Arabidopsis thaliana
    Jian Zhao
    Department of Biochemistry, Kansas State University, Manhattan, Kansas, United States of America
    PLoS ONE 6:e28086. 2011
    ..Our results suggest that PLDγs play a role in membrane lipid modulation under Al stress and that high activities of PLDγs negatively modulate plant tolerance to Al...
  10. pmc Enhanced seed viability and lipid compositional changes during natural ageing by suppressing phospholipase Dα in soybean seed
    Junghoon Lee
    Department of Plant Pathology, Kansas State University, Manhattan, KS, USA
    Plant Biotechnol J 10:164-73. 2012
    ..The data demonstrate that, during natural ageing, PLDα affects the soybean phospholipid profile and the TAG profile. Suppression of PLD activity in soybean seed has potential for improving seed quality during long-term storage...
  11. pmc The Arabidopsis thaliana dihydroxyacetone phosphate reductase gene SUPPRESSSOR OF FATTY ACID DESATURASE DEFICIENCY1 is required for glycerolipid metabolism and for the activation of systemic acquired resistance
    Ashis Nandi
    Division of Biology and Molecular, Cellular, and Developmental Biology Program, Kansas State University, Manhattan, Kansas 66506 4901
    Plant Cell 16:465-77. 2004
    ..Plastid glycerolipid composition was altered in the sfd1 mutant plant, suggesting that SFD1 is involved in lipid metabolism and that an SFD1 product lipid(s) is important for the activation of SAR...
  12. pmc Double knockouts of phospholipases Dzeta1 and Dzeta2 in Arabidopsis affect root elongation during phosphate-limited growth but do not affect root hair patterning
    Maoyin Li
    Department of Biochemistry, Kansas State University, Manhattan, Kansas 66506, USA
    Plant Physiol 140:761-70. 2006
    ..These results indicate that PLDzeta1 and PLDzeta2 play a role in regulating root development in response to nutrient limitation...
  13. pmc Levels of Arabidopsis thaliana Leaf Phosphatidic Acids, Phosphatidylserines, and Most Trienoate-Containing Polar Lipid Molecular Species Increase during the Dark Period of the Diurnal Cycle
    Sara Maatta
    Division of Biology, Kansas Lipidomics Research Center, Kansas State University Manhattan, KS, USA
    Front Plant Sci 3:49. 2012
    ..The polar lipid compositional changes are considered in relation to recent data that demonstrate phosphatidylcholine acyl editing...
  14. doi request reprint Arabidopsis phospholipase Dβ1 modulates defense responses to bacterial and fungal pathogens
    Jian Zhao
    Department of Biochemistry, Kansas State University, Manhattan, KS 66506, USA
    New Phytol 199:228-40. 2013
    ..PLDβ1 is responsible for most of the increase in PA production in response to necrotrophic B. cinerea and virulent Pst DC3000 infection, but contributes less to avirulent Pst DC3000 (avrRpt2)-induced PA production...
  15. pmc Steryl glucoside and acyl steryl glucoside analysis of Arabidopsis seeds by electrospray ionization tandem mass spectrometry
    Kathrin Schrick
    Division of Biology, 116 Ackert Hall, Kansas State University, Manhattan, KS 66506 4901, USA
    Lipids 47:185-93. 2012
    ..The results indicate that these glucosyltransferases account for much of the accumulation of the sterol conjugates in wild-type Arabidopsis seeds...
  16. doi request reprint Arabidopsis thaliana membrane lipid molecular species and their mass spectral analysis
    Thilani Samarakoon
    Kansas Lipidomics Research Center, Division of Biology, Kansas State University, Manhattan, KS, USA
    Methods Mol Biol 918:179-268. 2012
    ..Additionally, the identities of over 500 reported membrane lipid molecular species are assembled...
  17. doi request reprint Phospholipid and triacylglycerol profiles modified by PLD suppression in soybean seed
    Junghoon Lee
    Department of Plant Pathology, Kansas State University, Manhattan, KN, USA
    Plant Biotechnol J 9:359-72. 2011
    ..This would be consistent with PLD playing a positive role in that conversion. The data indicate that soybean PLD attenuation is a potentially useful approach to altering properties of edible and industrial soybean lecithin...
  18. ncbi request reprint Lipid species profiling: a high-throughput approach to identify lipid compositional changes and determine the function of genes involved in lipid metabolism and signaling
    Ruth Welti
    Division of Biology, Kansas State University, Manhattan, Kansas 66506, USA
    Curr Opin Plant Biol 7:337-44. 2004
    ....
  19. pmc The oleate-stimulated phospholipase D, PLDdelta, and phosphatidic acid decrease H2O2-induced cell death in Arabidopsis
    Wenhua Zhang
    Department of Biochemistry, Kansas State University, Manhattan, Kansas 66506, USA
    Plant Cell 15:2285-95. 2003
    ..These results demonstrate that activation of oleate-stimulated PLDdelta constitutes an important step in the plant response to H2O2 and increasing plant stress tolerance...
  20. doi request reprint Lipidomic analysis of plant membrane lipids by direct infusion tandem mass spectrometry
    Sunitha Shiva
    Division of Biology, Kansas Lipidomics Research Center, Kansas State University, Manhattan, KS, USA
    Methods Mol Biol 1009:79-91. 2013
    ..The mass spectral data are processed and combined, using the Web application LipidomeDB Data Calculation Environment, to create a lipid profile...
  21. pmc Arabidopsis sfd mutants affect plastidic lipid composition and suppress dwarfing, cell death, and the enhanced disease resistance phenotypes resulting from the deficiency of a fatty acid desaturase
    Ashis Nandi
    Division of Biology, Kansas State University, Manhattan, Kansas 66506, USA
    Plant Cell 15:2383-98. 2003
    ..Because the levels of plastid complex lipid species containing hexadecatrienoic acid are depressed in all of the sfd ssi2 npr1 plants, we propose that these lipids are involved in the manifestation of the ssi2-conferred phenotypes...
  22. ncbi request reprint New mass-spectrometry-based strategies for lipids
    Giorgis Isaac
    Division of Biology, Ackert Hall, Kansas State University, Manhattan, KS 66506, USA
    Genet Eng (N Y) 28:129-57. 2007
    ..Time-of-flight secondary ion mass spectrometry (TOF-SIMS) is particularly suited for imaging of tissues and cells...
  23. pmc Intestinal lipid alterations occur prior to antibody-induced prostaglandin E2 production in a mouse model of ischemia/reperfusion
    Byron L Sparkes
    University of Hertfordshire, Hatfield, England, UK Division of Biology, Kansas State University, Manhattan, KS 66506, USA
    Biochim Biophys Acta 1801:517-25. 2010
    ..These data indicate that IR-induced intestinal damage requires antibodies for Cox-2 stimulated PGE(2) production but not for production of lysoPC and free AA...
  24. pmc Lipidomic analysis of Toxoplasma gondii reveals unusual polar lipids
    Ruth Welti
    Kansas Lipidomics Research Center, Division of Biology, Kansas State University, Manhattan, Kansas 66506, USA
    Biochemistry 46:13882-90. 2007
    ..Combined with T. gondii genomic data, these lipidomic data will assist in elucidation of metabolic pathways for lipid biosynthesis in this important human pathogen...
  25. pmc Lipid profiles in wheat cultivars resistant and susceptible to tan spot and the effect of disease on the profiles
    Dongwon Kim
    Department of Plant Pathology, Kansas State University, Manhattan 66506, USA
    Phytopathology 103:74-80. 2013
    ..These findings suggest that lipid composition of wheat leaves may be a determining factor in the resistance response of cultivars to tan spot...
  26. pmc Weight Loss via exercise with controlled dietary intake may affect phospholipid profile for cancer prevention in murine skin tissues
    Ping Ouyang
    Department of Human Nutrition, Kansas State University, Manhattan, KS 66506, USA
    Cancer Prev Res (Phila) 3:466-77. 2010
    ....
  27. ncbi request reprint Lipid and oxylipin profiles during aging and sprout development in potato tubers (Solanum tuberosum L.)
    Marie Laure Fauconnier
    Unité de Chimie Générale et Organique, Faculte Universitaire des Sciences Agronomiques de Gembloux, Passage des Déportés 2, B 5030, Gembloux, Belgium
    Biochim Biophys Acta 1633:118-26. 2003
    ..The decrease in the amount of linoleic acid in complex lipids correlates well with the amount of 9-HPOD and colneleic acid produced...
  28. pmc Phospholipase Dalpha3 is involved in the hyperosmotic response in Arabidopsis
    Yueyun Hong
    Department of Biology, University of Missouri, St Louis, Missouri 63121, USA
    Plant Cell 20:803-16. 2008
    ..These data suggest that PLDalpha3 positively mediates plant responses to hyperosmotic stresses and that increased PLDalpha3 expression and associated lipid changes promote root growth, flowering, and stress avoidance...
  29. ncbi request reprint AtPLAI is an acyl hydrolase involved in basal jasmonic acid production and Arabidopsis resistance to Botrytis cinerea
    Wenyu Yang
    Department of Biology, University of Missouri, St Louis, Missouri 63121, USA
    J Biol Chem 282:18116-28. 2007
    ..The study shows that AtPLAI is an acyl hydrolase, rather than a specific phospholipase A. AtPLAI is involved in basal JA production and Arabidopsis resistance to the necrotrophic fungus B. cinerea...
  30. ncbi request reprint Differential degradation of extraplastidic and plastidic lipids during freezing and post-freezing recovery in Arabidopsis thaliana
    Weiqi Li
    Kunming Institute of Botany, Chinese Academy of Sciences, 132 Lanhei Road, Kunming 650204, China
    J Biol Chem 283:461-8. 2008
    ..These data suggest a negative role for PLDalpha1 and a positive role for PLDdelta in freezing tolerance...
  31. ncbi request reprint Signaling functions of phosphatidic acid
    Xuemin Wang
    Department of Biology, University of Missouri, St Louis, MO 63121, USA
    Prog Lipid Res 45:250-78. 2006
    ..The regulatory processes in which PA has been implicated include signaling pathways in cell growth, proliferation, reproduction, and responses to hormones and biotic and abiotic stresses...
  32. ncbi request reprint Potato tuber phospholipids contain colneleic acid in the 2-position
    Marie Laure Fauconnier
    Unité de Chimie Générale et Organique, Faculte Universitaire des Sciences Agronomiques de Gembloux, Passage des Déportés 2, B 5030 Gembloux, Belgium
    FEBS Lett 538:155-8. 2003
    ..Exact mass analysis of its fragments confirmed the identity of palmitoyl,colneloyl phosphatidylinositol. To our knowledge, this work represents the first identification of a colneleoyl phospholipid...
  33. pmc Quantitative profiling of Arabidopsis polar glycerolipids in response to phosphorus starvation. Roles of phospholipases D zeta1 and D zeta2 in phosphatidylcholine hydrolysis and digalactosyldiacylglycerol accumulation in phosphorus-starved plants
    Maoyin Li
    Department of Biology, University of Missouri, St Louis, Missouri 63121, USA
    Plant Physiol 142:750-61. 2006
    ..The results suggest that hydrolysis of phosphatidylcholine by PLD zetas during phosphorus starvation contributes to the supply of inorganic phosphorus for cell metabolism and diacylglycerol moieties for galactolipid synthesis...
  34. ncbi request reprint ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol
    Michael L Fitzgerald
    Lipid Metabolism Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Lipid Res 48:621-32. 2007
    ..They also demonstrate the utility of the Abca3 null mouse as a model for a devastating human disease...
  35. ncbi request reprint Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid traffic
    Rene Bartz
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9039, USA
    J Lipid Res 48:837-47. 2007
    ..These results suggest that droplets play a central role in ether lipid metabolism and intracellular lipid traffic...
  36. doi request reprint Simultaneous quantification of major phytohormones and related compounds in crude plant extracts by liquid chromatography-electrospray tandem mass spectrometry
    Xiangqing Pan
    Department of Biology, University of Missouri, St Louis, MO 63121, United States
    Phytochemistry 69:1773-81. 2008
    ..Structurally diverse compounds from complicated biological matrices are determined with high selectivity and sensitivity...
  37. pmc Tocopherols modulate extraplastidic polyunsaturated fatty acid metabolism in Arabidopsis at low temperature
    Hiroshi Maeda
    Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Cell 20:452-70. 2008
    ..These results provide biochemical and genetic evidence that plastid-synthesized tocopherols modulate ER PUFA metabolism early in the LT adaptation response of Arabidopsis...
  38. doi request reprint Subcellular localization and dynamics of a digalactolipid-like epitope in Toxoplasma gondii
    Cyrille Botté
    Unité Mixte de Recherche 5168, Centre National de la Recherche Scientifique Commissariat à l Energie, Institut de Recherches en Technologies et Sciences pour le Vivant, 38058 Grenoble, France
    J Lipid Res 49:746-62. 2008
    ..DGLE was detected in other Apicomplexa (i.e., Neospora, Plasmodium, Babesia, and Cryptosporidium)...
  39. ncbi request reprint Plastid omega3-fatty acid desaturase-dependent accumulation of a systemic acquired resistance inducing activity in petiole exudates of Arabidopsis thaliana is independent of jasmonic acid
    Ratnesh Chaturvedi
    Department of Biological Sciences, University of North Texas, Denton, TX 76203, USA
    Plant J 54:106-17. 2008
    ..In addition, JA did not co-purify with the SAR-inducing activity confirming that JA is not the mobile signal in SAR...
  40. ncbi request reprint Enhancing seed quality and viability by suppressing phospholipase D in Arabidopsis
    Shivakumar P Devaiah
    Department of Biology, University of Missouri, St Louis, MO 63121, USA
    Plant J 50:950-7. 2007
    ..A high level of PLDalpha1 is detrimental to seed quality, and attenuation of PLDalpha1 expression has the potential to improve oil stability, seed quality and seed longevity...
  41. pmc Electrospray ionization multiple stage quadrupole ion-trap and tandem quadrupole mass spectrometric studies on phosphatidylglycerol from Arabidopsis leaves
    Fong Fu Hsu
    Mass Spectrometry Resource, Division of Endocrinology, Diabetes, Metabolism, and Lipid Research, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
    J Am Soc Mass Spectrom 18:783-90. 2007
    ..This low-energy tandem mass spectrometric approach also permits the structures of the Arabidopsis PGs that consist of two isomeric structures to be unveiled...