E S Tasheva

Summary

Affiliation: Kansas State University
Country: USA

Publications

  1. pmc Expression studies of osteoglycin/mimecan (OGN) in the cochlea and auditory phenotype of Ogn-deficient mice
    Robin E Williamson
    Department of Genetics, Harvard Medical School, Boston, MA, USA
    Hear Res 237:57-65. 2008
  2. ncbi request reprint Mimecan/osteoglycin-deficient mice have collagen fibril abnormalities
    Elena S Tasheva
    Division of Biology, Kansas State University, Manhattan, KS 66506 4901, USA
    Mol Vis 8:407-15. 2002
  3. ncbi request reprint Analysis of transcriptional regulation of the small leucine rich proteoglycans
    Elena S Tasheva
    Kansas State University, Division of Biology, Manhattan, KS 66506 4901, USA
    Mol Vis 10:758-72. 2004
  4. ncbi request reprint Analysis of the expression of chondroadherin in mouse ocular and non-ocular tissues
    Elena S Tasheva
    Kansas State University, Division of Biology, Manhattan, KS 66506 4901, USA
    Mol Vis 10:544-54. 2004
  5. ncbi request reprint Differentially expressed genes in the lens of mimecan-null mice
    Elena S Tasheva
    Kansas State University, Division of Biology, Manhattan, KS 66506 4901, USA
    Mol Vis 10:403-16. 2004
  6. ncbi request reprint Interferon-gamma regulation of the human mimecan promoter
    Elena S Tasheva
    Division of Biology, Kansas State University, Manhattan 66506 4901, USA
    Mol Vis 9:277-87. 2003
  7. ncbi request reprint The UV responsive elements in the human mimecan promoter: a functional characterization
    Elena S Tasheva
    Kansas State University, Division of Biology, Manhattan, KS 66506 4901, USA
    Mol Vis 9:1-9. 2003
  8. ncbi request reprint Expression and localization of leucine-rich B7 protein in human ocular tissues
    Elena S Tasheva
    Division of Biology, Kansas State University, Manhattan, KS 66506 4901, USA
    Mol Vis 11:452-60. 2005
  9. ncbi request reprint Analysis of the promoter region of human mimecan gene
    Elena S Tasheva
    Division of Biology, Ackert Hall, Kansas State University, Manhattan, KS 66506 4901, USA
    Biochim Biophys Acta 1575:123-9. 2002
  10. ncbi request reprint Transcriptional activation of bovine mimecan by p53 through an intronic DNA-binding site
    E S Tasheva
    Division of Biology, Kansas State University, Manhattan 66506 4901, USA
    Biochim Biophys Acta 1517:333-8. 2001

Collaborators

Detail Information

Publications23

  1. pmc Expression studies of osteoglycin/mimecan (OGN) in the cochlea and auditory phenotype of Ogn-deficient mice
    Robin E Williamson
    Department of Genetics, Harvard Medical School, Boston, MA, USA
    Hear Res 237:57-65. 2008
    ..Ogn-deficient mice, when analyzed by auditory brainstem response and distortion product otoacoustic emissions, have normal hearing thresholds...
  2. ncbi request reprint Mimecan/osteoglycin-deficient mice have collagen fibril abnormalities
    Elena S Tasheva
    Division of Biology, Kansas State University, Manhattan, KS 66506 4901, USA
    Mol Vis 8:407-15. 2002
    ....
  3. ncbi request reprint Analysis of transcriptional regulation of the small leucine rich proteoglycans
    Elena S Tasheva
    Kansas State University, Division of Biology, Manhattan, KS 66506 4901, USA
    Mol Vis 10:758-72. 2004
    ..The purpose of this study was to determine whether there is evidence for control elements, which could regulate the expression of these clusters coordinately...
  4. ncbi request reprint Analysis of the expression of chondroadherin in mouse ocular and non-ocular tissues
    Elena S Tasheva
    Kansas State University, Division of Biology, Manhattan, KS 66506 4901, USA
    Mol Vis 10:544-54. 2004
    ..This finding prompted us to explore the expression of Chad in other ocular and non-ocular tissues...
  5. ncbi request reprint Differentially expressed genes in the lens of mimecan-null mice
    Elena S Tasheva
    Kansas State University, Division of Biology, Manhattan, KS 66506 4901, USA
    Mol Vis 10:403-16. 2004
    ..Here, we sought to identify gene expression changes in the lens that are associated with the absence of mimecan...
  6. ncbi request reprint Interferon-gamma regulation of the human mimecan promoter
    Elena S Tasheva
    Division of Biology, Kansas State University, Manhattan 66506 4901, USA
    Mol Vis 9:277-87. 2003
    ..The purpose of this study was to investigate whether IFN-gamma affects mimecan gene expression and, if so, to determine the cis-elements and transcription factors that mediate its action...
  7. ncbi request reprint The UV responsive elements in the human mimecan promoter: a functional characterization
    Elena S Tasheva
    Kansas State University, Division of Biology, Manhattan, KS 66506 4901, USA
    Mol Vis 9:1-9. 2003
    ..Mimecan is an extracellular matrix proteoglycan that is abundantly expressed in the cornea. The purpose of this study was to determine and characterize the UV responsive regulatory elements of the human mimecan promoter...
  8. ncbi request reprint Expression and localization of leucine-rich B7 protein in human ocular tissues
    Elena S Tasheva
    Division of Biology, Kansas State University, Manhattan, KS 66506 4901, USA
    Mol Vis 11:452-60. 2005
    ..The purpose of this study was to determine the expression of leucine-rich B7 protein in human eye tissues and its subcellular localization in MG-63 cells...
  9. ncbi request reprint Analysis of the promoter region of human mimecan gene
    Elena S Tasheva
    Division of Biology, Ackert Hall, Kansas State University, Manhattan, KS 66506 4901, USA
    Biochim Biophys Acta 1575:123-9. 2002
    ....
  10. ncbi request reprint Transcriptional activation of bovine mimecan by p53 through an intronic DNA-binding site
    E S Tasheva
    Division of Biology, Kansas State University, Manhattan 66506 4901, USA
    Biochim Biophys Acta 1517:333-8. 2001
    ..In addition, we show absence of mimecan expression in different tumors and cancer cell lines, where p53 frequently is inactivated/mutated. Thus, this work provides novel information that links mimecan to the p53 network...
  11. ncbi request reprint Identification and characterization of conserved cis-regulatory elements in the human keratocan gene promoter
    E S Tasheva
    Division of Biology, Ackert Hall, Kansas State University, Manhattan, KS 66506 4901, USA
    Biochim Biophys Acta 1492:452-9. 2000
    ..Competition experiments indicate that the CTC factor and a protein that binds to the CAGA motif are likely to be among the multiple factors involved in the transcriptional regulation of the human Kera gene...
  12. ncbi request reprint Assignment of mimecan gene (OGN) to human chromosome band 9q22 by in situ hybridization
    E S Tasheva
    Division of Biology, Kansas State University, Manhattan 66506, USA
    Cytogenet Cell Genet 88:326-7. 2000
  13. ncbi request reprint Assignment of keratocan gene (KERA) to human chromosome band 12q22 by in situ hybridization
    E S Tasheva
    Division of Biology, Kansas State University, Manhattan 66506, USA
    Cytogenet Cell Genet 88:244-5. 2000
  14. ncbi request reprint Structure and sequence of the gene encoding human keratocan
    E S Tasheva
    Division of Biology, Kansas State University, Manhattan 66506 4901, USA
    DNA Seq 10:67-74. 1999
    ..This evolutionary conservation between the keratocan proteins as well as the restricted expression of Kera gene in cornea suggests that this molecule might be important in developing and maintaining corneal transparency...
  15. ncbi request reprint The bovine mimecan gene. Molecular cloning and characterization of two major RNA transcripts generated by alternative use of two splice acceptor sites in the third exon
    E S Tasheva
    Division of Biology, Kansas State University, Manhattan, Kansas 66506 4901, USA
    J Biol Chem 274:18693-701. 1999
    ..We demonstrated that their expression is differentially modulated in a temporal manner by basic fibroblast growth factor...
  16. ncbi request reprint Cloning, characterization and tissue-specific expression of the gene encoding bovine keratocan, a corneal keratan sulfate proteoglycan
    E S Tasheva
    Division of Biology, Kansas State University, Manhattan, KS 66506 4901, USA
    Gene 218:63-8. 1998
    ..This restricted expression in eye tissues, as well as the unique modification of keratocan with long keratan sulfate chains in cornea, suggests that this molecule may be important in developing and maintaining corneal transparency...
  17. ncbi request reprint Differential splicing and alternative polyadenylation generate multiple mimecan mRNA transcripts
    E S Tasheva
    Division of Biology, Kansas State University, Manhattan, Kansas 66506 4901, USA
    J Biol Chem 272:32551-6. 1997
    ..Possible roles for this previously undetected degree of diversity of mimecan RNA isoforms transcribed in the same tissue are discussed...
  18. ncbi request reprint Mimecan, the 25-kDa corneal keratan sulfate proteoglycan, is a product of the gene producing osteoglycin
    J L Funderburgh
    Division of Biology, Kansas State University, Manhattan, Kansas 66506 4901, USA
    J Biol Chem 272:28089-95. 1997
    ..The multiple size protein products of this gene appear to result from in situ proteolytic processing and/or alternative splicing of mRNA. The name mimecan is proposed for this gene and its products...
  19. ncbi request reprint Detection and quantification of sulfated disaccharides from keratan sulfate and chondroitin/dermatan sulfate during chick corneal development by ESI-MS/MS
    Yuntao Zhang
    Division of Biology, Kansas State University, Manhattan, KS 66506, USA
    Invest Ophthalmol Vis Sci 46:1604-14. 2005
    ..To identify and quantify changes in keratan sulfate (KS) and chondroitin/dermatan sulfate (CS/DS) sulfated disaccharides in the developing chick cornea using electrospray ionization tandem mass spectrometry (ESI-MS/MS)...
  20. ncbi request reprint Analysis of keratan sulfate oligosaccharides by electrospray ionization tandem mass spectrometry
    Yuntao Zhang
    Division of Biology, Kansas State University, Manhattan, KS 66506, USA
    Anal Chem 77:902-10. 2005
    ....
  21. pmc Proteomic analysis of potential keratan sulfate, chondroitin sulfate A, and hyaluronic acid molecular interactions
    Abigail H Conrad
    Division of Biology, Kansas State University, Manhattan, Kansas 66506 4901, USA
    Invest Ophthalmol Vis Sci 51:4500-15. 2010
    ..This study asked which of the proteins that may regulate keratocytes or corneal nerve growth cone immigration interact with corneal GAGs...
  22. ncbi request reprint Regulation of human RPS14 transcription by intronic antisense RNAs and ribosomal protein S14
    E S Tasheva
    Division of Biology, Kansas State University, Manhattan 66506 4901
    Genes Dev 9:304-16. 1995
    ..In light of these data, we propose a model for fine regulation of human RPS14 transcription that involves RPS14 intron 1 antisense RNAs as positive effectors and S14 protein as a negative effector...
  23. pmc Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass
    Enrico Petretto
    Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK
    Nat Genet 40:546-52. 2008
    ..Taken together, these data implicate Ogn as a key regulator of LVM in rats, mice and humans, and suggest that Ogn modifies the hypertrophic response to extrinsic factors such as hypertension and aortic stenosis...