MICHAEL KENNEY

Summary

Affiliation: Kansas State University
Country: USA

Publications

  1. ncbi request reprint Cold stress alters characteristics of sympathetic nerve discharge bursts
    M J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    J Appl Physiol 87:732-42. 1999
  2. ncbi request reprint Senescence alters blood flow responses to acute heat stress
    Michael J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USA
    Am J Physiol Heart Circ Physiol 286:H1480-5. 2004
  3. ncbi request reprint Forebrain and brain stem neural circuits contribute to altered sympathetic responses to heating in senescent rats
    Michael J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    J Appl Physiol 95:1986-93. 2003
  4. ncbi request reprint Role of paraventricular nucleus in regulation of sympathetic nerve frequency components
    Michael J Kenney
    Department of Anatomy and Physiology, Kansas State University, 1600 Denison Avenue, Manhattan, KS 66506, USA
    Am J Physiol Heart Circ Physiol 284:H1710-20. 2003
  5. ncbi request reprint Sympathoexcitation to intravenous interleukin-1beta is dependent on forebrain neural circuits
    Michael J Kenney
    Department of Anatomy and Physiology, Coles Hall Rm 228, Kansas State University, 1600 Denison Avenue, Manhattan, KS 66506, USA
    Am J Physiol Heart Circ Physiol 283:H501-5. 2002
  6. ncbi request reprint Sympathetic nerve regulation to heating is altered in senescent rats
    Michael J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Am J Physiol Regul Integr Comp Physiol 283:R513-20. 2002
  7. ncbi request reprint Altered frequency responses of sympathetic nerve discharge bursts after IL-1beta and mild hypothermia
    M J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan 66506, USA
    J Appl Physiol 93:280-8. 2002
  8. ncbi request reprint Interleukin-1 beta alters brown adipose tissue but not renal sympathetic nerve responses to hypothermia
    M J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Am J Physiol Heart Circ Physiol 281:H2441-5. 2001
  9. ncbi request reprint Paraventricular nucleus bicuculline alters frequency components of sympathetic nerve discharge bursts
    M J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Am J Physiol Heart Circ Physiol 281:H1233-41. 2001
  10. ncbi request reprint Renal sympathetic nerve regulation to heating is altered in rats with heart failure
    M J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Am J Physiol Heart Circ Physiol 280:H2868-75. 2001

Research Grants

  1. Sympathetic-Immune Interface: Central Sites & Function
    MICHAEL KENNEY; Fiscal Year: 2005
  2. SENESCENCE ALTERS SYMPATHETIC REGULATION TO HEAT STRESS
    MICHAEL KENNEY; Fiscal Year: 2004
  3. BRITE VETERINARY STUDENT PROGRAM
    Michael J Kenney; Fiscal Year: 2010

Collaborators

  • Yan Wang
  • T I Musch
  • Mark Weiss
  • SUSAN BARMAN
  • Bryan G Helwig
  • Richard J Fels
  • Chanran K Ganta
  • Ning Lu
  • Frank Blecha
  • Sujatha Parimi
  • Roman R Ganta
  • Kimberley G Hosking
  • Robin A Craig
  • Richard Cober
  • Christopher R Ross
  • Ling Zheng
  • Heather P Hoch

Detail Information

Publications20

  1. ncbi request reprint Cold stress alters characteristics of sympathetic nerve discharge bursts
    M J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    J Appl Physiol 87:732-42. 1999
    ..We conclude that hypothermia profoundly alters the organization of neural circuits involved in regulation of sympathetic nerve outflow to selected regional circulations...
  2. ncbi request reprint Senescence alters blood flow responses to acute heat stress
    Michael J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USA
    Am J Physiol Heart Circ Physiol 286:H1480-5. 2004
    ..These results demonstrate a marked attenuation in heating-induced vascular conductance changes in senescent rats, suggesting an important functional consequence for the attenuated SND responses to heating in aged rats...
  3. ncbi request reprint Forebrain and brain stem neural circuits contribute to altered sympathetic responses to heating in senescent rats
    Michael J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    J Appl Physiol 95:1986-93. 2003
    ..These results support the concept that aging alters the functional organization of pathways regulating SND and arterial blood pressure responses to acute heating...
  4. ncbi request reprint Role of paraventricular nucleus in regulation of sympathetic nerve frequency components
    Michael J Kenney
    Department of Anatomy and Physiology, Kansas State University, 1600 Denison Avenue, Manhattan, KS 66506, USA
    Am J Physiol Heart Circ Physiol 284:H1710-20. 2003
    ....
  5. ncbi request reprint Sympathoexcitation to intravenous interleukin-1beta is dependent on forebrain neural circuits
    Michael J Kenney
    Department of Anatomy and Physiology, Coles Hall Rm 228, Kansas State University, 1600 Denison Avenue, Manhattan, KS 66506, USA
    Am J Physiol Heart Circ Physiol 283:H501-5. 2002
    ....
  6. ncbi request reprint Sympathetic nerve regulation to heating is altered in senescent rats
    Michael J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Am J Physiol Regul Integr Comp Physiol 283:R513-20. 2002
    ..These results demonstrate an attenuated responsiveness of sympathetic neural circuits to heating in senescent F344 rats...
  7. ncbi request reprint Altered frequency responses of sympathetic nerve discharge bursts after IL-1beta and mild hypothermia
    M J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan 66506, USA
    J Appl Physiol 93:280-8. 2002
    ..These data demonstrate functional plasticity in sympathetic neural circuits and suggest complex relationships between immune products and SND regulation...
  8. ncbi request reprint Interleukin-1 beta alters brown adipose tissue but not renal sympathetic nerve responses to hypothermia
    M J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Am J Physiol Heart Circ Physiol 281:H2441-5. 2001
    ..These data suggest that IL-1 beta alters IBAT SND responses to acute and sustained hypothermia...
  9. ncbi request reprint Paraventricular nucleus bicuculline alters frequency components of sympathetic nerve discharge bursts
    M J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Am J Physiol Heart Circ Physiol 281:H1233-41. 2001
    ..We conclude that PVN GABA(A) receptor antagonism profoundly alters the frequency components in sympathetic nerves...
  10. ncbi request reprint Renal sympathetic nerve regulation to heating is altered in rats with heart failure
    M J Kenney
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Am J Physiol Heart Circ Physiol 280:H2868-75. 2001
    ..These results demonstrate a marked attenuation in the responsiveness of renal SND to heating in HF rats and suggest that HF alters the organization of neural pathways mediating SND responses to heating...
  11. ncbi request reprint Aging alters regulation of visceral sympathetic nerve responses to acute hypothermia
    Bryan G Helwig
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Am J Physiol Regul Integr Comp Physiol 291:R573-9. 2006
    ....
  12. ncbi request reprint Central angiotensin II-enhanced splenic cytokine gene expression is mediated by the sympathetic nervous system
    Chanran K Ganta
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas, USA
    Am J Physiol Heart Circ Physiol 289:H1683-91. 2005
    ....
  13. ncbi request reprint Hyperthermia-enhanced splenic cytokine gene expression is mediated by the sympathetic nervous system
    Chanran K Ganta
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Physiol Genomics 19:175-83. 2004
    ..These results support the hypothesis that hyperthermia-induced activation of splenic SND enhances splenic cytokine gene expression...
  14. ncbi request reprint Central interleukin-1beta antibody increases renal and splenic sympathetic nerve discharge
    Ning Lu
    Department of Anatomy and Physiology, Kansas State University, 1600 Denison Avenue, Manhattan, KS 66506, USA
    Am J Physiol Heart Circ Physiol 284:H1536-41. 2003
    ..These results suggest that under the conditions of the present experiments central neural IL-1beta plays a role in the tonic regulation of SND and arterial blood pressure...
  15. ncbi request reprint Hypothermia-enhanced splenic cytokine gene expression is independent of the sympathetic nervous system
    Chanran K Ganta
    Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas 66506, USA
    Am J Physiol Regul Integr Comp Physiol 291:R558-65. 2006
    ..These results suggest that hypothermia-enhanced splenic cytokine gene expression is independent of splenic SND...
  16. pmc Inhibition of RVLM synaptic activation at peak hyperthermia reduces visceral sympathetic nerve discharge
    Kimberley G Hosking
    Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USA
    Auton Neurosci 150:104-10. 2009
    ..5 degrees C) than normothermia (38 degrees C). These findings demonstrate that maintenance of sympathetic activation at peak hyperthermia is dependent on the integrity of RVLM neural circuits...
  17. ncbi request reprint Central Tempol alters basal sympathetic nerve discharge and attenuates sympathetic excitation to central ANG II
    Ning Lu
    Dept of Anatomy and Physiology, Coles Hall 228, Kansas State Univ, 1600 Denison Ave, Manhattan, KS 66506, USA
    Am J Physiol Heart Circ Physiol 287:H2626-33. 2004
    ..These results demonstrate that icv Tempol administration influences central sympathetic neural circuits in a dose-dependent manner and attenuates SND responses to central ANG II infusion...
  18. pmc Central nervous system administration of interleukin-6 produces splenic sympathoexcitation
    Bryan G Helwig
    Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, United States
    Auton Neurosci 141:104-11. 2008
    ..These results demonstrate that icv IL-6 administration increases splenic SND, an effect likely achieved via signaling mechanisms originating in the periventricular cells...
  19. ncbi request reprint Increased interleukin-6 receptor expression in the paraventricular nucleus of rats with heart failure
    Bryan G Helwig
    Department of Anatomy and Physiology, Coles Hall 228, Kansas State University, 1600 Denison Ave, Manhattan, KS 66506, USA
    Am J Physiol Regul Integr Comp Physiol 292:R1165-73. 2007
    ..Rather the increased IL-6 levels characteristic of HF may alter PVN-mediated physiological responses via enhanced expression of the IL-6R...
  20. ncbi request reprint Methods of analysis and physiological relevance of rhythms in sympathetic nerve discharge
    Susan M Barman
    Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824, USA
    Clin Exp Pharmacol Physiol 34:350-5. 2007
    ....

Research Grants11

  1. Sympathetic-Immune Interface: Central Sites & Function
    MICHAEL KENNEY; Fiscal Year: 2005
    ..Ultimately, these findings may allow for the design of intervention strategies in immune regulation fostering robust and appropriate communication between the immune and nervous systems. ..
  2. SENESCENCE ALTERS SYMPATHETIC REGULATION TO HEAT STRESS
    MICHAEL KENNEY; Fiscal Year: 2004
    ..The proposed studies will, for the first time, advance the hypothesis that the working strategies employed by sympathetic neural circuits to respond to heat stress are modified by aging. ..
  3. BRITE VETERINARY STUDENT PROGRAM
    Michael J Kenney; Fiscal Year: 2010
    ..The proposed training program will encourage veterinary students to pursue this career path. ..