Research Topics
Genomes and GenesSpecies | Anny H XiangSummaryAffiliation: Kaiser Permanente Country: USA Publications
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Detail Information
Publications
Genetics of gestational diabetes mellitus and type 2 diabetesRichard M Watanabe
Department of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, CA 90089-9011, USA
Diabetes Care 30:S134-40. 2007- Detailed physiological characterization of the development of type 2 diabetes in Hispanic women with prior gestational diabetes mellitusAnny H Xiang
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Diabetes 59:2625-30. 2010..To identify physiological and clinical variables associated with development of type 2 diabetes up to 12 years after pregnancies complicated by gestational diabetes... - Self-reported physical activity is associated with β-cell function in Mexican American adultsZhanghua Chen
Division of Biostatistics, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Diabetes Care 36:638-44. 2013..To examine the association between self-reported physical activity (PA) and diabetes-related quantitative traits... 
Racial and ethnic disparities in diabetes risk after gestational diabetes mellitusA H Xiang
Department of Research and Evaluation, Kaiser Permanente Southern California, 100 S Los Robles, 5th Floor, Pasadena, CA 91101, USA
Diabetologia 54:3016-21. 2011..To investigate racial/ethnic disparities in diabetes risk after gestational diabetes mellitus (GDM)...- Effect of pioglitazone on progression of subclinical atherosclerosis in non-diabetic premenopausal Hispanic women with prior gestational diabetesAnny H Xiang
Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, United States
Atherosclerosis 199:207-14. 2008..Pioglitazone slows progression of subclinical atherosclerosis in young Hispanic women at increased risk for type 2 diabetes... 
Effect of thiazolidinedione treatment on progression of subclinical atherosclerosis in premenopausal women at high risk for type 2 diabetesAnny H Xiang
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Room 6602 GNH, 1200 North State Street, Los Angeles, California 90089-9317, USA
J Clin Endocrinol Metab 90:1986-91. 2005..Troglitazone reduced the progression of subclinical atherosclerosis via a mechanism that involved unmeasured mediators of atherosclerosis, either in the circulation or directly in the arterial wall...- Pharmacological treatment of insulin resistance at two different stages in the evolution of type 2 diabetes: impact on glucose tolerance and beta-cell functionAnny H Xiang
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
J Clin Endocrinol Metab 89:2846-51. 2004..These findings highlight the role of insulin resistance in the genesis of progressive beta-cell dysfunction during the evolution of type 2 diabetes... - Replication of calpain-10 genetic association with carotid intima-media thicknessMark O Goodarzi
Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Atherosclerosis 205:503-5. 2009..A prior study in Hispanics found association of haplotypes in the diabetes gene calpain-10 (CAPN10) with carotid artery intima-media thickness (CIMT). This study sought to replicate this association in an independent cohort... - Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican AmericansXia Li
Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine of USC, Los Angeles, California, USA
Obesity (Silver Spring) 17:729-36. 2009..066) and disposition index (DI) (Bonferroni P = 0.072). We conclude that rs11705701 in IGF2BP2 is associated with body fat and this effect on body fat influences insulin resistance which may contribute to T2DM risk... - Effect of pioglitazone on pancreatic beta-cell function and diabetes risk in Hispanic women with prior gestational diabetesAnny H Xiang
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, USA
Diabetes 55:517-22. 2006.... - Declining beta-cell compensation for insulin resistance in Hispanic women with recent gestational diabetes mellitus: association with changes in weight, adiponectin, and C-reactive proteinAnny H Xiang
Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles, California, USA
Diabetes Care 33:396-401. 2010..To identify factors associated with declining beta-cell compensation for insulin resistance... - Coordinate changes in plasma glucose and pancreatic beta-cell function in Latino women at high risk for type 2 diabetesAnny H Xiang
Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles, CA, USA
Diabetes 55:1074-9. 2006..Only relatively late in this process do glucose levels rise rapidly and into the diabetic range... - Evidence for sex-specific associations between variation in acid phosphatase locus 1 (ACP1) and insulin sensitivity in Mexican-AmericansYu Hsiang Shu
Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine of the University of Southern California, Los Angeles, California 90033, USA
J Clin Endocrinol Metab 94:4094-102. 2009..Acid phosphatase locus 1 (ACP1) is a low molecular weight tyrosine phosphatase that has been shown to be an important regulator of insulin receptor signaling... - A longitudinal study of lipids and blood pressure in relation to method of contraception in Latino women with prior gestational diabetes mellitusAnny H Xiang
Keck School of Medicine, University of Southern California, Department of Preventive Medicine, 1540 Alcazar St, CHP 222, Los Angeles, CA 90033, USA
Diabetes Care 30:1952-8. 2007..To investigate the effect of nonhormonal contraception (NHC), combination oral contraception (COC), and depo-medroxyprogesterone acetate (DMPA) on lipids and blood pressure in women with recent gestational diabetes mellitus (GDM)... - Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucoseXia Li
Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Diabetes 58:2946-53. 2009..GCK rs1799884 and G6PC2 rs560887 have been independently associated with fasting glucose, but their interaction on glucose-insulin relationships is not well characterized... - Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican AmericansMary Helen Black
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar St, CHP 220, Los Angeles, CA 90089 9011, USA
Diabetes 57:1048-56. 2008.... - Carotid intima-media thickness (cIMT) cosegregates with blood pressure and renal function in hypertensive Hispanic familiesYi Chun Chen
Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
Atherosclerosis 198:160-5. 2008..Since cIMT is correlated with hypertension and microalbuminuria, we tested the hypothesis that there is a genetic basis for the observed relationship between cIMT, blood pressure (BP), and renal function within high risk families... - Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic womenThomas A Buchanan
Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
Diabetes 51:2796-803. 2002..The protective effect was associated with the preservation of pancreatic beta-cell function and appeared to be mediated by a reduction in the secretory demands placed on beta-cells by chronic insulin resistance... - Long-acting injectable progestin contraception and risk of type 2 diabetes in Latino women with prior gestational diabetes mellitusAnny H Xiang
Keck School of Medicine, University of Southern California, Department of Preventive Medicine, 1540 Alcazar St, CHP 222, Los Angeles, CA 90033, USA
Diabetes Care 29:613-7. 2006.... - Insulin resistance and preeclampsia in gestational diabetes mellitusMartin N Montoro
Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, USA
Diabetes Care 28:1995-2000. 2005..To compare the degree of insulin resistance in women with gestational diabetes mellitus (GDM) who do and do not develop preeclampsia... - Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican AmericansRichard M Watanabe
Division of Biostatistics, Department of Preventive Medicine, Keck School of Medicine, The University of Southern California, Los Angeles, California 90089 9011, USA
Diabetes 56:1481-5. 2007..We examined variation in a 0.1-Mb region surrounding marker DG10S478 for association with diabetes-related quantitative traits in 132 Mexican-American families of a proband with previous gestational diabetes mellitus (GDM)... - Gestational diabetes mellitusThomas A Buchanan
Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90089 9317, USA
J Clin Invest 115:485-91. 2005..Thus, GDM provides a unique opportunity to study the early pathogenesis of diabetes and to develop interventions to prevent the disease... - Deterioration in cardiometabolic risk markers in obese women during depot medroxyprogesterone acetate usePenina Segall-Gutierrez
Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Contraception 85:36-41. 2012..The purpose of this 18-week prospective experimental study was to compare the impact of subcutaneous depot medroxyprogesterone acetate (DMPA-SC) on cardiometabolic markers in obese and normal-weight women... - Clinical outcomes of pregnancies complicated by mild gestational diabetes mellitus differ by combinations of abnormal oral glucose tolerance test valuesMary Helen Black
Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA
Diabetes Care 33:2524-30. 2010.... - A better index of body adiposityRichard N Bergman
Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Obesity (Silver Spring) 19:1083-9. 2011..It can be used in the clinical setting even in remote locations with very limited access to reliable scales. The BAI estimates %adiposity directly... - The relative contribution of prepregnancy overweight and obesity, gestational weight gain, and IADPSG-defined gestational diabetes mellitus to fetal overgrowthMary Helen Black
Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA
Diabetes Care 36:56-62. 2013.... - Use of medications to prevent type 2 diabetesThomas A Buchanan
Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
Curr Diab Rep 5:237-9. 2005 - The linear cutting stapler may reduce surgical time and blood loss with muscle transection: a pilot studyDaniel C Allison
Division of Musculoskeletal Oncology, Southern California Permanente Medical Group, 1011 Baldwin Park Boulevard, Baldwin Park, CA, 91706, USA
Clin Orthop Relat Res 467:2859-64. 2009..LEVEL OF EVIDENCE: Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence... - Gestational diabetes mellitus: risks and management during and after pregnancyThomas A Buchanan
Division of Endocrinology and Diabetes, Department of Medicine, Keck School of Medicine of the University of Southern California, 2250 Alcazar Street, CSC 205, Los Angeles, CA 90033, USA
Nat Rev Endocrinol 8:639-49. 2012..Family planning enables optimization of health in subsequent pregnancies. Breastfeeding may reduce obesity in children and is recommended. Families should be encouraged to help children adopt lifestyles that reduce the risk of obesity... - Heritability of subclinical atherosclerosis in Latino families ascertained through a hypertensive parentAnny H Xiang
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles 90033, USA
Arterioscler Thromb Vasc Biol 22:843-8. 2002..Heritability is particularly evident in younger family members, suggesting that acquired factors contribute progressively to IMT variability with aging...