Anny H Xiang

Summary

Affiliation: Kaiser Permanente
Country: USA

Publications

  1. pmc Genetics of gestational diabetes mellitus and type 2 diabetes
    Richard M Watanabe
    Department of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, CA 90089 9011, USA
    Diabetes Care 30:S134-40. 2007
  2. pmc Detailed physiological characterization of the development of type 2 diabetes in Hispanic women with prior gestational diabetes mellitus
    Anny H Xiang
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Diabetes 59:2625-30. 2010
  3. doi request reprint HOMA and Matsuda indices of insulin sensitivity: poor correlation with minimal model-based estimates of insulin sensitivity in longitudinal settings
    A H Xiang
    Department of Research and Evaluation, Kaiser Permanente Southern California, 100 S Los Robles, 5th Floor, Pasadena, CA, 91101, USA
    Diabetologia 57:334-8. 2014
  4. doi request reprint Longitudinal changes in insulin sensitivity and beta cell function between women with and without a history of gestational diabetes mellitus
    Anny H Xiang
    Department of Research and Evaluation, Kaiser Permanente Southern California, 100 South Los Robles, 5th Floor, Pasadena, CA, 91101, USA
    Diabetologia 56:2753-60. 2013
  5. doi request reprint Racial and ethnic disparities in diabetes risk after gestational diabetes mellitus
    A H Xiang
    Department of Research and Evaluation, Kaiser Permanente Southern California, 100 S Los Robles, 5th Floor, Pasadena, CA 91101, USA
    Diabetologia 54:3016-21. 2011
  6. pmc Effect of pioglitazone on progression of subclinical atherosclerosis in non-diabetic premenopausal Hispanic women with prior gestational diabetes
    Anny H Xiang
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, United States
    Atherosclerosis 199:207-14. 2008
  7. ncbi request reprint Pharmacological treatment of insulin resistance at two different stages in the evolution of type 2 diabetes: impact on glucose tolerance and beta-cell function
    Anny H Xiang
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 89:2846-51. 2004
  8. pmc Replication of calpain-10 genetic association with carotid intima-media thickness
    Mark O Goodarzi
    Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Atherosclerosis 205:503-5. 2009
  9. ncbi request reprint Effect of thiazolidinedione treatment on progression of subclinical atherosclerosis in premenopausal women at high risk for type 2 diabetes
    Anny H Xiang
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Room 6602 GNH, 1200 North State Street, Los Angeles, California 90089 9317, USA
    J Clin Endocrinol Metab 90:1986-91. 2005
  10. doi request reprint Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans
    Xia Li
    Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine of USC, Los Angeles, California, USA
    Obesity (Silver Spring) 17:729-36. 2009

Detail Information

Publications39

  1. pmc Genetics of gestational diabetes mellitus and type 2 diabetes
    Richard M Watanabe
    Department of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, CA 90089 9011, USA
    Diabetes Care 30:S134-40. 2007
  2. pmc Detailed physiological characterization of the development of type 2 diabetes in Hispanic women with prior gestational diabetes mellitus
    Anny H Xiang
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Diabetes 59:2625-30. 2010
    ..To identify physiological and clinical variables associated with development of type 2 diabetes up to 12 years after pregnancies complicated by gestational diabetes...
  3. doi request reprint HOMA and Matsuda indices of insulin sensitivity: poor correlation with minimal model-based estimates of insulin sensitivity in longitudinal settings
    A H Xiang
    Department of Research and Evaluation, Kaiser Permanente Southern California, 100 S Los Robles, 5th Floor, Pasadena, CA, 91101, USA
    Diabetologia 57:334-8. 2014
    ....
  4. doi request reprint Longitudinal changes in insulin sensitivity and beta cell function between women with and without a history of gestational diabetes mellitus
    Anny H Xiang
    Department of Research and Evaluation, Kaiser Permanente Southern California, 100 South Los Robles, 5th Floor, Pasadena, CA, 91101, USA
    Diabetologia 56:2753-60. 2013
    ..The aim of the study was to compare longitudinal changes in insulin sensitivity (SI) and beta cell function between women with and without a history of gestational diabetes mellitus (GDM)...
  5. doi request reprint Racial and ethnic disparities in diabetes risk after gestational diabetes mellitus
    A H Xiang
    Department of Research and Evaluation, Kaiser Permanente Southern California, 100 S Los Robles, 5th Floor, Pasadena, CA 91101, USA
    Diabetologia 54:3016-21. 2011
    ..To investigate racial/ethnic disparities in diabetes risk after gestational diabetes mellitus (GDM)...
  6. pmc Effect of pioglitazone on progression of subclinical atherosclerosis in non-diabetic premenopausal Hispanic women with prior gestational diabetes
    Anny H Xiang
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, United States
    Atherosclerosis 199:207-14. 2008
    ..Pioglitazone slows progression of subclinical atherosclerosis in young Hispanic women at increased risk for type 2 diabetes...
  7. ncbi request reprint Pharmacological treatment of insulin resistance at two different stages in the evolution of type 2 diabetes: impact on glucose tolerance and beta-cell function
    Anny H Xiang
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 89:2846-51. 2004
    ..These findings highlight the role of insulin resistance in the genesis of progressive beta-cell dysfunction during the evolution of type 2 diabetes...
  8. pmc Replication of calpain-10 genetic association with carotid intima-media thickness
    Mark O Goodarzi
    Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Atherosclerosis 205:503-5. 2009
    ..A prior study in Hispanics found association of haplotypes in the diabetes gene calpain-10 (CAPN10) with carotid artery intima-media thickness (CIMT). This study sought to replicate this association in an independent cohort...
  9. ncbi request reprint Effect of thiazolidinedione treatment on progression of subclinical atherosclerosis in premenopausal women at high risk for type 2 diabetes
    Anny H Xiang
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Room 6602 GNH, 1200 North State Street, Los Angeles, California 90089 9317, USA
    J Clin Endocrinol Metab 90:1986-91. 2005
    ..Troglitazone reduced the progression of subclinical atherosclerosis via a mechanism that involved unmeasured mediators of atherosclerosis, either in the circulation or directly in the arterial wall...
  10. doi request reprint Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans
    Xia Li
    Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine of USC, Los Angeles, California, USA
    Obesity (Silver Spring) 17:729-36. 2009
    ..066) and disposition index (DI) (Bonferroni P = 0.072). We conclude that rs11705701 in IGF2BP2 is associated with body fat and this effect on body fat influences insulin resistance which may contribute to T2DM risk...
  11. ncbi request reprint Coordinate changes in plasma glucose and pancreatic beta-cell function in Latino women at high risk for type 2 diabetes
    Anny H Xiang
    Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles, CA, USA
    Diabetes 55:1074-9. 2006
    ..Only relatively late in this process do glucose levels rise rapidly and into the diabetic range...
  12. pmc Effect of pioglitazone on pancreatic beta-cell function and diabetes risk in Hispanic women with prior gestational diabetes
    Anny H Xiang
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, USA
    Diabetes 55:517-22. 2006
    ....
  13. pmc Declining beta-cell compensation for insulin resistance in Hispanic women with recent gestational diabetes mellitus: association with changes in weight, adiponectin, and C-reactive protein
    Anny H Xiang
    Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles, California, USA
    Diabetes Care 33:396-401. 2010
    ..To identify factors associated with declining beta-cell compensation for insulin resistance...
  14. pmc High-fat diet is associated with obesity-mediated insulin resistance and β-cell dysfunction in Mexican Americans
    Mary Helen Black
    Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA
    J Nutr 143:479-85. 2013
    ..These findings suggest that high-fat diets may contribute to increased adiposity and concomitant insulin resistance and β-cell dysfunction in Mexican Americans...
  15. pmc Evidence for sex-specific associations between variation in acid phosphatase locus 1 (ACP1) and insulin sensitivity in Mexican-Americans
    Yu Hsiang Shu
    Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine of the University of Southern California, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 94:4094-102. 2009
    ..Acid phosphatase locus 1 (ACP1) is a low molecular weight tyrosine phosphatase that has been shown to be an important regulator of insulin receptor signaling...
  16. ncbi request reprint A longitudinal study of lipids and blood pressure in relation to method of contraception in Latino women with prior gestational diabetes mellitus
    Anny H Xiang
    Keck School of Medicine, University of Southern California, Department of Preventive Medicine, 1540 Alcazar St, CHP 222, Los Angeles, CA 90033, USA
    Diabetes Care 30:1952-8. 2007
    ..To investigate the effect of nonhormonal contraception (NHC), combination oral contraception (COC), and depo-medroxyprogesterone acetate (DMPA) on lipids and blood pressure in women with recent gestational diabetes mellitus (GDM)...
  17. pmc Self-reported physical activity is associated with β-cell function in Mexican American adults
    Zhanghua Chen
    Division of Biostatistics, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Diabetes Care 36:638-44. 2013
    ..To examine the association between self-reported physical activity (PA) and diabetes-related quantitative traits...
  18. ncbi request reprint Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans
    Mary Helen Black
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar St, CHP 220, Los Angeles, CA 90089 9011, USA
    Diabetes 57:1048-56. 2008
    ....
  19. pmc Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose
    Xia Li
    Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Diabetes 58:2946-53. 2009
    ..GCK rs1799884 and G6PC2 rs560887 have been independently associated with fasting glucose, but their interaction on glucose-insulin relationships is not well characterized...
  20. ncbi request reprint Carotid intima-media thickness (cIMT) cosegregates with blood pressure and renal function in hypertensive Hispanic families
    Yi Chun Chen
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Atherosclerosis 198:160-5. 2008
    ..Since cIMT is correlated with hypertension and microalbuminuria, we tested the hypothesis that there is a genetic basis for the observed relationship between cIMT, blood pressure (BP), and renal function within high risk families...
  21. ncbi request reprint Insulin resistance and preeclampsia in gestational diabetes mellitus
    Martin N Montoro
    Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, USA
    Diabetes Care 28:1995-2000. 2005
    ..To compare the degree of insulin resistance in women with gestational diabetes mellitus (GDM) who do and do not develop preeclampsia...
  22. ncbi request reprint Long-acting injectable progestin contraception and risk of type 2 diabetes in Latino women with prior gestational diabetes mellitus
    Anny H Xiang
    Keck School of Medicine, University of Southern California, Department of Preventive Medicine, 1540 Alcazar St, CHP 222, Los Angeles, CA 90033, USA
    Diabetes Care 29:613-7. 2006
    ....
  23. ncbi request reprint Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women
    Thomas A Buchanan
    Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Diabetes 51:2796-803. 2002
    ..The protective effect was associated with the preservation of pancreatic beta-cell function and appeared to be mediated by a reduction in the secretory demands placed on beta-cells by chronic insulin resistance...
  24. pmc Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans
    Richard M Watanabe
    Division of Biostatistics, Department of Preventive Medicine, Keck School of Medicine, The University of Southern California, Los Angeles, California 90089 9011, USA
    Diabetes 56:1481-5. 2007
    ..We examined variation in a 0.1-Mb region surrounding marker DG10S478 for association with diabetes-related quantitative traits in 132 Mexican-American families of a proband with previous gestational diabetes mellitus (GDM)...
  25. ncbi request reprint Genetic variation in MTNR1B is associated with gestational diabetes mellitus and contributes only to the absolute level of beta cell compensation in Mexican Americans
    Jie Ren
    Department of Preventive Medicine, Keck School of Medicine of USC, 2250 Alcazar St, Los Angeles, CA, 90089 9073, USA
    Diabetologia 57:1391-9. 2014
    ..We hypothesised that variation in MTNR1B contributes to the absolute level of a diabetes-related trait, temporal rate of change in that trait, or both...
  26. doi request reprint Metabolic syndrome is less likely to resolve in Hispanics and non-Hispanic blacks after bariatric surgery
    Karen J Coleman
    Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena and Department of Metabolic and Bariatric Medicine, Kaiser Permanente Southern California Panorama City Medical Center, Panorama City
    Ann Surg 259:279-85. 2014
    ..To determine predictors of metabolic syndrome and its resolution in a large, ethnically diverse adult population undergoing bariatric surgery...
  27. pmc Gestational diabetes mellitus
    Thomas A Buchanan
    Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90089 9317, USA
    J Clin Invest 115:485-91. 2005
    ..Thus, GDM provides a unique opportunity to study the early pathogenesis of diabetes and to develop interventions to prevent the disease...
  28. pmc Gestational diabetes mellitus, maternal obesity, and adiposity in offspring
    Kathleen A Page
    Department of Medicine, Keck School of Medicine, The University of Southern California, Los Angeles, CA Electronic address
    J Pediatr 164:807-10. 2014
    ..To determine the effects of maternal gestational diabetes mellitus (GDM) on offspring adiposity in a well-characterized cohort of Mexican American mother-child pairs...
  29. pmc The relative contribution of prepregnancy overweight and obesity, gestational weight gain, and IADPSG-defined gestational diabetes mellitus to fetal overgrowth
    Mary Helen Black
    Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA
    Diabetes Care 36:56-62. 2013
    ....
  30. doi request reprint Deterioration in cardiometabolic risk markers in obese women during depot medroxyprogesterone acetate use
    Penina Segall-Gutierrez
    Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Contraception 85:36-41. 2012
    ..The purpose of this 18-week prospective experimental study was to compare the impact of subcutaneous depot medroxyprogesterone acetate (DMPA-SC) on cardiometabolic markers in obese and normal-weight women...
  31. pmc Clinical outcomes of pregnancies complicated by mild gestational diabetes mellitus differ by combinations of abnormal oral glucose tolerance test values
    Mary Helen Black
    Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA
    Diabetes Care 33:2524-30. 2010
    ....
  32. pmc Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans
    Mark O Goodarzi
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA Medical Genetics Research Institute, Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, California, USA
    Obesity (Silver Spring) 22:1157-64. 2014
    ..The GUARDIAN (Genetics UndeRlying DIAbetes in HispaNics) consortium is described, along with heritability estimates and genetic and environmental correlations of insulin sensitivity and metabolic clearance rate of insulin (MCRI)...
  33. pmc A better index of body adiposity
    Richard N Bergman
    Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Obesity (Silver Spring) 19:1083-9. 2011
    ..It can be used in the clinical setting even in remote locations with very limited access to reliable scales. The BAI estimates %adiposity directly...
  34. ncbi request reprint Use of medications to prevent type 2 diabetes
    Thomas A Buchanan
    Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    Curr Diab Rep 5:237-9. 2005
  35. doi request reprint Racial and ethnic differences in time to treatment for patients with localized prostate cancer
    Kimberly R Porter
    Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA 91101, USA
    Urology 81:283-7. 2013
    ..To investigate the racial/ethnic differences in the time to treatment among patients with prostate cancer...
  36. pmc The linear cutting stapler may reduce surgical time and blood loss with muscle transection: a pilot study
    Daniel C Allison
    Division of Musculoskeletal Oncology, Southern California Permanente Medical Group, 1011 Baldwin Park Boulevard, Baldwin Park, CA, 91706, USA
    Clin Orthop Relat Res 467:2859-64. 2009
    ....
  37. ncbi request reprint Associations between Physical Activity and 30-Day Readmission Risk in Chronic Obstructive Pulmonary Disease
    Huong Q Nguyen
    1 Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California
    Ann Am Thorac Soc 11:695-705. 2014
    ..Although it is possible that lower physical activity is a reflection of worse disease, promoting and supporting physical activity is a promising strategy to reduce the risk of readmission. ..
  38. ncbi request reprint Heritability of subclinical atherosclerosis in Latino families ascertained through a hypertensive parent
    Anny H Xiang
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles 90033, USA
    Arterioscler Thromb Vasc Biol 22:843-8. 2002
    ..Heritability is particularly evident in younger family members, suggesting that acquired factors contribute progressively to IMT variability with aging...
  39. doi request reprint Gestational diabetes mellitus: risks and management during and after pregnancy
    Thomas A Buchanan
    Division of Endocrinology and Diabetes, Department of Medicine, Keck School of Medicine of the University of Southern California, 2250 Alcazar Street, CSC 205, Los Angeles, CA 90033, USA
    Nat Rev Endocrinol 8:639-49. 2012
    ..Family planning enables optimization of health in subsequent pregnancies. Breastfeeding may reduce obesity in children and is recommended. Families should be encouraged to help children adopt lifestyles that reduce the risk of obesity...